Publication Date:
2003-07-19
Description:
The principles underlying human hemispheric specialization are poorly understood. We used functional magnetic resonance imaging of letter and visuospatial decision tasks with identical word stimuli to address two unresolved problems. First, hemispheric specialization depended on the nature of the task rather than on the nature of the stimulus. Second, analysis of frontal candidate regions for cognitive control showed increased coupling between left anterior cingulate cortex (ACC) and left inferior frontal gyrus during letter decisions, whereas right ACC showed enhanced coupling with right parietal areas during visuospatial decisions. Cognitive control is thus localized in the same hemisphere as task execution.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Stephan, Klaas E -- Marshall, John C -- Friston, Karl J -- Rowe, James B -- Ritzl, Afra -- Zilles, Karl -- Fink, Gereon R -- 077029/Wellcome Trust/United Kingdom -- New York, N.Y. -- Science. 2003 Jul 18;301(5631):384-6.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Institute of Medicine (IME), Research Centre Julich, 52425 Julich, Germany.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/12869765" target="_blank"〉PubMed〈/a〉
Keywords:
Adult
;
Brain/*physiology
;
Brain Mapping
;
*Cognition
;
Functional Laterality
;
Gyrus Cinguli/physiology
;
Humans
;
*Language
;
Magnetic Resonance Imaging
;
Male
;
Parietal Lobe/physiology
;
Prefrontal Cortex/physiology
;
Space Perception
;
Visual Perception
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
