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  • 1
    Online Resource
    Online Resource
    Coronary Artery Disease: Therapeutics and Drug Discovery (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Cardiology. ; Therapeutics. ; Heart Surgery. ; Pharmacology. ; Cardiology. ; Therapeutics. ; Cardiac Surgery.
    Description / Table of Contents: Coronary Artery Disease: From Mechanism to Clinical Practice -- Evidence in guidelines for treatment of coronary artery disease -- Revascularization For Coronary Artery Disease: Principle And Challenges -- Antithrombotic drugs: pharmacology and perspectives -- Lipid modifying drugs: pharmacology and perspectives -- Anti-hypertensive drugs: pharmacology and perspectives -- Pharmaceutical treatment for Heart failure -- Drug discovery for coronary artery disease.
    Abstract: This book provides an overview of the etiology of coronary artery disease and focuses on the main therapies and drug interventions currently available. It highlights drug pharmacology and therapeutic challenges, with a special emphasis on the underlying principles of available therapeutics and the on-going development of drugs for coronary artery disease. The book is divided into eight chapters, the first of which describes the classical mechanism of coronary artery disease and its clinical presentations. Chapter 2 lists the principles of and related evidence on the prevention and treatment of coronary artery disease. This includes diet and lifestyle management, and guidelines for the treatment of acute coronary syndrome and stable coronary artery disease. In turn, Chapter 3 describes revascularization treatments, covering percutaneous coronary interventions, coronary artery bypass grafts and thrombolysis. This chapter also addresses the main therapeutic challenges. The following chapters provide an overview of three major categories of coronary artery disease drugs, which target thrombosis (Chapter 4), lipid metabolism (Chapter 5), and hypertension (Chapter 6). Heart failure constitutes the major health burden in the late stage of coronary artery disease; accordingly, current heart failure therapeutics and related drug pharmacology are described in Chapter 7. In closing, Chapter 8 provides a summary of on-going clinical trials for coronary artery disease drug development and discusses a number of promising areas in which intensive research into new therapeutics is being pursued. Given its scope, the book will be of interest to clinicians, medical students and research scientists, as well as to pharmaceutical professionals who are seeking new therapies and drugs for coronary artery disease and related disorders.
    Type of Medium: Online Resource
    Pages: IX, 339 p. 7 illus., 4 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811525179
    Series Statement: Advances in Experimental Medicine and Biology, 1177
    URL: https://doi.org/10.1007/978-981-15-2517-9
    DOI: 10.1007/978-981-15-2517-9
    DDC: 615
    Language: English
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  • 2
    Online Resource
    Online Resource
    Pediatric Pharmacotherapy (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Pediatrics. ; Pharmacology. ; Pediatrics.
    Description / Table of Contents: Anti-epileptic drugs in pediatrics -- Current and new therapies for Duchenne Muscular Dystrophy -- Lysosomal diseases -- Mitochondriopathies -- Endocrinology thyroid, pituitary, growth stimulant, growth reduction -- Bone disease – bisphosphonates -- Diabetes type 1 and 3 (insulin; sulfonylurea; others) -- Diabetes type 2 (metformin etc.) -- Dermatology – part 1 urticaria, atopic dermatitis -- Dermatology part 2, ichtyosis, psoriasis -- Cardiovascular part 1- catcholamines, inotropic -- Cardiovascular part 2 – antiarhythmica, anti hypertensives -- Nephrology – dialysis -- How to use drugs in obese children and adolescents -- Haematology – CSFs, erythropoietin -- Antiretroviral/HIV -- Clinical pharmacology and pharmacometrics to better understand physiological changes during pregnancy and neonatal life -- Antihelminth treatment -- Inflammatory bowel disease -- Constipation; laxatives -- Psychiatric diseases in children and adolescents -- Oncology – cell reducing agents part 1, part 2, part 3 -- Immunosuppressants – organ transplantation -- Bone marrow/stem cell transplantation -- Narcotic sparing approaches and the shift towards paracetamol in neonatal intensive care -- Disorders of puberty: pharmacotherapeutic strategies for management.
    Abstract: This volume provides readers with the most updated scientific information on the efficacy and safety of medicines for children and adolescents. The book enriches the understanding of pediatric pharmacotherapy for health professionals, regulatory agencies, pharmaceutical companies and learned societies. It contains important information on the pharmacodynamics and pharmacokinetics of drugs. It summarizes the latest investigations on the effects of pharmacological treatments in relation to and dependent on age, gender, fat mass and disease status. Therefore and importantly, this volume reviews the latest data on how pharmacotherapy has to be adjusted and personalized in regards to stages of development and during the pediatric lifespan from neonate through adolescence. In addition, the topic of rare diseases and special challenges for pharmacotherapy will be included and will provide readers with the necessary knowledge to handle complex diseases and treatment strategies especially in relation to pharmacotherapy of rare and orphan diseases.
    Type of Medium: Online Resource
    Pages: VIII, 538 p. 1 illus. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030504946
    Series Statement: Handbook of Experimental Pharmacology, 261
    URL: https://doi.org/10.1007/978-3-030-50494-6
    DOI: 10.1007/978-3-030-50494-6
    DDC: 615
    Language: English
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  • 3
    Online Resource
    Online Resource
    Reactive Oxygen Species : Network Pharmacology and Therapeutic Applications (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Cardiology. ; Neurosciences. ; Clinical biochemistry. ; Pharmacology. ; Cardiology. ; Neuroscience. ; Medical Biochemistry.
    Description / Table of Contents: Part I: ROS Revisited: Changing the Focus from Oxidative Stress and Redox Biology to Redox Medicine -- Demystifying oxidative stress -- Oxidants in Physiological Processes -- Network Medicine-Based Unbiased Disease Modules for Drug and Diagnostic Target Identification in ROSopathies -- Part II Targeting antioxidant responses -- Development of Telintra as an Inhibitor of Glutathione S-Transferase P -- Perspectives on the Clinical Development of NRF2-Targeting Drugs -- Part III: Inhibiting ROS formation and toxification -- NOX Inhibitors: From Bench to Naxibs to Bedside -- Nitric Oxide Synthase Inhibitors into the Clinic at Last -- Xanthine Oxidoreductase Inhibitors -- Monoamine Oxidase Inhibitors: From Classic to New Clinical Approaches -- Inhibition of Myeloperoxidase -- Part IV: Stimulating/substituting ROS -- Effects of Mammalian Thioredoxin Reductase Inhibitors -- Cardiovascular Therapeutic Potential of the Redox Siblings, Nitric Oxide (NO•) and Nitroxyl (HNO), in the Setting of Reactive Oxygen Species Dysregulation -- Tetrahydrobiopterin and Nitric Oxide Synthase Recouplers -- Part V: Repairing ROS damage -- Soluble Guanylate Cyclase Stimulators and Activators – Peter Sander -- Inhibitors of Advanced Glycation End Product (AGE) Formation and Accumulation.
    Abstract: Reactive oxygen species (ROS) have been implicated in almost every human disease phenotype, without much, if any, therapeutic consequence foremost exemplified by the failure of the so-called anti-oxidants. This book is a game changer for the field and many clinical areas such as cardiology and neurology. The term ‘oxidative stress’ is abandoned and replaced with a systems medicine and network pharmacology-based mechanistic approach to disease. The ROS-related drugs discussed here target either ROS- forming or ROS -modifying enzymes for which there is strong clinical evidence. In addition, ROS targets are included as they jointly participate in causal mechanisms of disease. This approach is transforming the ROS field and represents a breakthrough in redox medicine indicating a path to patient benefit. In the coming years more targets and drugs may be discovered, but the approach will remain the same and this book will thus become, and for many years remain, the leading reference for ROSopathies and their treatment by network pharmacology. Chapter "Soluble Guanylate Cyclase Stimulators and Activators" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Type of Medium: Online Resource
    Pages: VIII, 425 p. 70 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030685102
    Series Statement: Handbook of Experimental Pharmacology, 264
    URL: https://doi.org/10.1007/978-3-030-68510-2
    DOI: 10.1007/978-3-030-68510-2
    DDC: 615
    Language: English
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  • 4
    Online Resource
    Online Resource
    Organotypic Models in Drug Development (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Medical genetics. ; Pathology. ; Pharmacology. ; Clinical Genetics. ; Pathology.
    Description / Table of Contents: Inflammatory skin disease models in vitro and in animals – predictability for drug development -- Neural In Vitro Models for Studying Substances Acting on the Central Nervous System -- Quality of commercial tissues Standardised Reconstructed Skin Models in Toxicology and Pharmacology: State of the Art and Future Development -- Human-Derived In Vitro Models Used for Skin Toxicity Testing Under REACh -- Disease Models: Lung models for testing drugs against inflammation and infection -- In Vitro Models of the Blood-Brain Barrier -- How Qualification of 3D Disease Models Cuts the Gordian Knot in Preclinical Drug Development -- The CAM Assay as an Alternative In Vivo Model for Drug Testing -- Organotypic Models in Drug Development “Tumor Models and Cancer Systems Biology for the Investigation of Anticancer Drugs and Resistance Development -- Tissue Engineering for Musculoskeletal Regeneration and Disease Modeling -- Immunocompetent human intestinal models in preclinical drug development -- Engineered Heart Muscle Models in Phenotypic Drug Screens.
    Abstract: This book provides latest findings in organotypic models in drug development and provides the scientific resonance needed in an emerging field of research in disciplines, such as molecular medicine, physiology, and pathophysiology. Today the research on human-based test systems has gained major interest and funding in the EU and the US has increased over the last years. Moreover, so-called 3R (reduce, replace, refine animal experiments) centres have been established worldwide.
    Type of Medium: Online Resource
    Pages: VIII, 323 p. 70 illus., 37 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030700638
    Series Statement: Handbook of Experimental Pharmacology, 265
    URL: https://doi.org/10.1007/978-3-030-70063-8
    DOI: 10.1007/978-3-030-70063-8
    DDC: 615
    Language: English
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  • 5
    Online Resource
    Online Resource
    Vaccination Strategies Against Highly Variable Pathogens (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Diseases. ; Virology. ; Immunology. ; Human physiology. ; Pharmacology. ; Diseases. ; Virology. ; Immunology. ; Human Physiology.
    Description / Table of Contents: Successful Vaccines -- Immunogenicity and Immunodominance in Antibody Responses -- Immunogen Design -- Adjuvants -- Tools to screen vaccines -- Targeting glycans on human pathogens for vaccine design -- BnAbs and highly antigenically variable pathogens.
    Abstract: Vaccines against antigenically stable pathogens, or pathogens that only exist in a limited number of serotypes, have been very successful in the past and have drastically decreased the incidence and lethality of many diseases. However, when it comes to highly variable pathogens or viruses that exist in multiple serotypes, the traditional methods for vaccine development have reached their limits. This volume highlights the development of vaccines against such challenging pathogens. Novel approaches for immunogen design, including structure-guided vaccine development and vaccines targeting glycans, as well as adjuvants and animal models used for testing possible vaccine candidates are outlined and discussed in detail. Given its scope, the book will appeal to scientists in the fields of infectious diseases, microbiology and medicine. .
    Type of Medium: Online Resource
    Pages: VII, 180 p. 16 illus., 15 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030580049
    Series Statement: Current Topics in Microbiology and Immunology, 428
    URL: https://doi.org/10.1007/978-3-030-58004-9
    DOI: 10.1007/978-3-030-58004-9
    DDC: 615
    Language: English
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  • 6
    Online Resource
    Online Resource
    Drug Stability and Chemical Kinetics (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Pharmacology. ; Pharmaceutics.
    Description / Table of Contents: 1 Principles of pharmaceutical analysis in drug stability and chemical kinetics -- 2 Guidelines for drug stability and stability testing -- 3 Chemical kinetics and its applications in drug stability -- 4 Methods and protocols for drug stability studies -- 5 Physical basis of degradation of pharmaceutical products -- 6 Role of microbiological degradation on drug stability -- 7 Role of decomposition on drug stability -- 8 Role of catalysis in drug stability -- 9 Analytical techniques for the assessment of drug stability -- 10 Stability of pharmaceutical products -- 11 Role of kinetic models in drug stability -- 12 Stability studies of vaccines -- 13 Stability studies of proteinous compounds -- 14 Stability studies of extemporaneous pharmaceutical products -- 15 Stability studies of parenteral products -- 16 Stability studies of solid dosage forms.
    Abstract: This book comprehensively reviews drug stability and chemical kinetics: how external factors can influence the stability of drugs, and the reaction rates that trigger these effects. Explaining the important theoretical concepts of drug stability and chemical kinetics, and providing numerous examples in the form of illustrations, tables and calculations, the book helps readers gain a better understanding of the rates of reactions, order of reactions, types of degradation and how to prevent it, as well as types of stability studies. It also offers insights into the importance of the rate at which the drug is degraded and/or decomposed under various external and internal conditions, including temperature, pH, humidity and light. This book is intended for researchers, PhD students and scientists working in the field of pharmacy, pharmacology, pharmaceutical chemistry, medicinal chemistry and biopharmaceutics. .
    Type of Medium: Online Resource
    Pages: XIV, 284 p. 22 illus., 13 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811564260
    URL: https://doi.org/10.1007/978-981-15-6426-0
    DOI: 10.1007/978-981-15-6426-0
    DDC: 615
    Language: English
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  • 7
    Online Resource
    Online Resource
    Handbook of 200 Medicinal Plants : A Comprehensive Review of Their Traditional Medical Uses and Scientific Justifications (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Pharmacy. ; Medicinal chemistry. ; Pharmacology. ; Pharmacy. ; Medicinal Chemistry.
    Description / Table of Contents: Abelmoschus maschatus -- Abrus precatorius -- Abutilon indicum -- Acacia catechu -- Acacia nilotica (A. arabica) -- Achillea millefolium -- Achyranthes aspera -- Aconitum napellus -- Acorus calamus -- Adiantum venustum (Adiantun capillus-veneris) -- Aegle marmelos -- Agrimonia eupatorium.-Alhagi maurorum -- Alkanna tinctoria -- Allium cepa -- Allium sativum -- Aloe vera -- Alpinia galangal -- Alpinia officinarum -- Alstonia scholaris -- Althaea officinalis -- Ammi majus -- Anacardium occidentale -- Anacyclus pyrethrum -- Andrographis paniculata -- Anethum graveolens -- Anthemis nobilis -- Apium graveolens -- Argemone Mexicana -- Aristolochia bracteolata -- Aristolochia fontanesii (A. longa) -- Aristolochia indica -- Aristolochia rotunda -- Artemisia absinthium -- Artemisia vulgaris -- Asparagus adscendens -- Asparagus officinalis -- Asparagus racemosus -- Atropa belladonna -- Azadirachta indica -- Bacopa monnieri -- Bauhinia tomentosa -- Berberis Aristata -- Berberis vulgaris -- Bombyx mori -- Borago officinalis -- Boswellia serrata -- Brassica nigra -- Butea monosperma -- Caccinia macranthera var. glauca (C. glauca) -- Caesalpinia bonduc (Caesalpinia bonducella) -- Cannabis sativa -- Capparis spinosa -- Cardiospermum halicacabum -- Carthamus tinctorius -- Carum carvi -- Cassia fistula -- Catharanthus roseus -- Celastrus paniculatus -- Centaurea behen -- Centella asiatica -- Chamaecrista absus (Cassia absus) -- Chamaemelum nobile (Anthemis nobilis) -- Cheilocostus speciosus (Costus Speciosus) -- Cichorium intybus -- Cinnamomum camphora -- Cinnamomum cassia -- Cinnamomum verum (C. zeylanicum) -- Citrullus colocynthis -- Clitoria ternatea -- Colchicum autumnale -- Colchicum luteum -- Commiphora gileadensis (C. opobalsamum) -- Commiphora myrrha -- Commiphora wightii (C. mukul) -- Convolvulus scammonia -- Cotoneaster nummularius -- Crocus sativus -- Croton tiglium -- Cullen corylifolium (Psoralea corylifolia) -- Cuminum cyminum -- Curcuma aromatica -- Curcuma longa -- Curcuma zedoaria -- Cuscuta chinensis -- Cuscuta reflexa -- Cydonia oblonga -- Cymbopogon schoenanthus -- Cyperus rotundus -- Datura stramonium -- Delphinium denudatum -- Dolichousnea longissimi (Usnea longissima) -- Doronicum pardalianches -- Embelia ribes -- Euphorbia hirta -- Euphorbia resinifera -- Ferula assa-foetida -- Ficus carica -- Ficus racemosa -- Foeniculum vulgare -- Fumaria officinalis -- Gentiana lutea -- Glycyrrhiza glabra -- Gymnema sylvestre -- Helleborus niger -- Hemidesmus Indicus -- Hibiscus rosa-sinensis -- Holarrhena pubescens (Holarrhena antidysenterica) -- Hyoscyamus niger -- Hyssopus officinalis -- Illicium verum -- Iris germanica -- Juniperus communi -- Justicia adhatoda (Adhatoda vasica) -- Lactuca sativa -- Lavandula stoechas -- Lawsonia inermis -- Lepidium sativum -- Linum usitatissimum -- Lupinus albus -- Malva sylvestris -- Marrubium vulgare -- Matricaria chamomilla -- Melia azedarach -- Melilotus officinalis -- Melissa officinalis -- Mesua ferrea -- Momordica charantia -- Moringa oleifera -- Myristica fragrans -- Myrtus communis -- Nageia nagi -- Nepeta cataria -- Nigella sativa -- Ocimum basilicum -- Ocimum gratissimum -- Ocimum tenuiflorum (Ocimum sanctum -- Operculina turpethum -- Paeonia emodi -- Pandanus odorifer (Pandanus Odoratissimus) -- Papaver somniferum -- Persicaria bistorta -- Phyllanthus emblica (Emblica officinalis) -- Picrorhiza kurroa -- Pimpinella anisum -- Piper cubeba -- Piper nigrum -- Pistacia lentiscus -- Plantago major -- Plantago ovata -- Plumbago zeylanica -- Polygonum aviculare -- Portulaca oleracea -- Quercus infectoria -- Rauvolfia serpentina -- Rheum emodi -- Rheum officinale -- Ricinus communis -- Rubia cordifolia -- Rumex vesicarius -- Ruta graveolens -- Salix caprea -- Salvia officinalis -- Santalum album -- Saussurea lappa -- Semecarpus anacardium -- Senna alexandrina -- Senna occidentalis -- Senna tora -- Sida cordifolia -- Smilax china;- Solanum americanum (S. nigrum) -- Sterculia urens -- Strychnos nux-vomica -- Swertia chirata -- Symplocos racemosa -- Syzygium cumini (Eugenia jambolana) -- Tamarindus indica -- Taraxacum officinale -- Taxus baccata -- Tephrosia purpurea -- Terminalia bellirica -- Terminalia chebula -- Thymus vulgaris -- Tinospora cordifolia -- Trachyspermum ammi (Ptychotis coptica) -- Tribulus terrestris -- Trigonella foenum-graecum -- Tussilago farfara -- Valeriana jatamansi (Nardostachys jatamansi) -- Verbena officinalis -- Vernonia anthelmintica (Baccharoides anthelmintica) -- Vigna unguiculata (Dolichos biflorus) -- Viola odorata -- Viscum album -- Withania somnifera -- Wrightia tinctoria -- Zingiber officinale -- Zingiber zerumbet -- Ziziphus jujuba -- Abbreviations -- Glossary -- Ayurvedic Terms of Diseases -- List of Referenced Books -- Index.
    Abstract: This book is designed to provide pharmacologists and researchers of natural products a comprehensive review of 200 medicinal plants, their vernacular names in various languages and their medicinal uses around the world, and in some cases, a historical perspective. Chemical constituents of each plant with the putative active constituent, and available up to date pharmacological studies (until 2017 on PubMed) with each medical activity explored and its relationship with traditional uses, are described for each plant. Any variations in chemical constituents and their effects on pharmacological studies outcome have been highlighted. All clinical trials conducted, with sufficient details, have been included. Nationalities and racial identities of participants of clinical trials are identified to impress upon the social, cultural and dietary influences on the clinical outcomes. Toxicity studies and potential interactions with prescribed drugs, and full spectrum of references are included.
    Type of Medium: Online Resource
    Pages: XXX, 2156 p. 199 illus., 198 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030168070
    URL: https://doi.org/10.1007/978-3-030-16807-0
    DOI: 10.1007/978-3-030-16807-0
    DDC: 615
    Language: English
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  • 8
    Online Resource
    Online Resource
    Therapeutic Applications of Dopamine D3 Receptor Function : New Insight After 30 Years Of Research (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Neurosciences. ; Psychiatry. ; Pharmacology. ; Neuroscience. ; Psychiatry.
    Description / Table of Contents: Preface -- A Historic Review of the D3 Dopamine System from D3 Cloning to Clinical Trials in Schizophrenia and Drug Addiction -- Location, Location, Location: The Expression of D3 Dopamine Receptors in the Nervous System -- Recent Advances in Dopamine D3 Receptor Heterodimers: Focus on Dopamine D3 and D1 Receptor-Receptor Interaction and Striatal Function -- Involvement of DA D3 Receptor and Mitochondrial Functions in Structural Neuroplasticity of the Emotional Brain Circuits: Possible Role in Depression -- Dopamine D3 Receptor in Parkinson Disease: A Prognosis Biomarker and an Intervention Target -- Dopamine D3 Receptors: A Potential Target to Treat Motivational Deficits in Parkinson’s Disease -- Therapeutic Challenges of Cognitive Dysfunctions in Neuropsychiatric Disorders: Focus on the Dopamine D3 Receptor -- Dopamine D3 Receptor in Stimulant and Opiate Use Disorders -- The Role of D3 Dopamine-Receptors in Nicotine Dependence: A Synthesis of the Pre-Clinical and Clinical Literature -- The Dopamine D3 receptor in Food Addiction -- The Dopamine D3 Receptor Pharmacology and the Therapeutic Use of D3 Receptor Ligands in Schizophrenia -- D3 receptors and Restless Legs Syndrome -- D3 receptors and PET imaging.
    Abstract: The CTBN volume Therapeutic Applications of Dopamine D3 Receptor Function reviews the state of the knowledge on the dopamine D3 receptor and its role in human behavior and disease (i.e.: neuropsychiatric illnesses including schizophrenia, mood disorders, Parkinson’s disease, restless legs syndrome, addictions and substance use disorders). The volume is written by leading experts across multidisciplinary areas (imaging, biobehavioral testing and clinical trials, preclinical models / molecular pharmacology) converging on the therapeutic implications / potential of the D3 receptor. The D3 dopamine receptor is a member of the D2-like family of G protein-coupled receptors. It was cloned and characterized almost 25 years ago. A key feature of the D3 dopamine receptor system, which has attracted considerable attention, is its anatomical localization remarkably restricted to the limbic circuitry. This has spurred the hypothesis that D3 involvement could contribute to the pathophysiology of neuropsychiatric disorders (or to some features of neuropsychiatric disorders), including but not limited to psychosis, addictions and substance abuse, mood and movement disorders.
    Type of Medium: Online Resource
    Pages: VIII, 275 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031230585
    Series Statement: Current Topics in Behavioral Neurosciences, 60
    URL: https://doi.org/10.1007/978-3-031-23058-5
    DOI: 10.1007/978-3-031-23058-5
    DDC: 615
    Language: English
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  • 9
    Online Resource
    Online Resource
    Approaching Complex Diseases : Network-Based Pharmacology and Systems Approach in Bio-Medicine (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Bioinformatics. ; Oncology. ; Medicine Philosophy. ; Pharmacology. ; Computational and Systems Biology. ; Oncology. ; Philosophy of Medicine.
    Description / Table of Contents: Chapter 1. Revisiting the concept of human disease (Mariano Bizzarri, Mirko Minini, and Noemi Monti) -- Chapter 2. Dynamical aspects of pharmacokinetic/pharmacodynamics and quantitative systems pharmacology models (Ioannis Loisios-Konstantinidis, Panteleimon D. Mavroudis, Panos Macheras) -- Chapter 3. The efficiency of multi-target drugs: a network approach (Lucas N. Alberca, Alan Talevi) -- Chapter 4. Mining Complex Biomedical Literature for Actionable Knowledge on Rare Diseases (Vinicius M. Alvesa, Stephen J. Capuzzia, Nancy Baker, Eugene N. Muratov, Alexander Trospsha, and Anthony J. Hickey) -- Chapter 5. Big Data, Personalized Medicine and Network Pharmacology: beyond the current paradigms (Alessandro Giuliani and Virginia Todde) -- Chapter 6. Epigenetic Control Using Small Molecules in Cancer (Tomohiro Kozako, Yukihiro Itoh, Shinichiro Honda, Takayoshi Suzuki) -- Chapter 7. Multiscale Modelling of Cancer: Micro-, Meso- and Macro-scales of Growth and Spread (Mark AJ Chaplain) -- Chapter 8. Precision Oncology vs Phenotypic approaches in the management of cancer: a case for the postmitotic state (Armando Aranda-Anzaldo and Myrna A.R. Dent) -- Chapter 9. Migrastatics - anti-metastatic drugs targeting cancer cell invasion (Aneta Gandalovičová , Daniel Rosel , Jan Brábek) -- Chapter 10. Critical steps in Epithelial-Mesenchymal transition as target for cancer treatment (Evgeny V. Denisov, Mohit Kumar Jolly, Vitaly P. Shubin, Alexey S. Tsukanov, Nadezhda V. Cherdyntseva) -- Chapter 11. Targeting the tumor-associated macrophages for ‘normalizing’ cancer (Julia Kzhyshkowska) -- Chapter 12. Tumor Reversion induced by embryo and oocyte extracts (Sara Proietti, Andrea Pensotti and Alessandra Cucina) -- Chapter 13. Trabectedin, a drug acting on both cancer cells and the tumor microenvironment (Paola Allavena, Manuela Liguori, Cristina Belgiovine) -- Chapter 14. Advances in Characterizing Recently-identified Molecular Actions of Melatonin: Clinical Implications (Russel J. Reiter, Ramaswamy Sharma, Sergio A. Rosales-Corral, Ana Coto-Montes, Jose Antonio Boga, Jerry Vriend) -- Chapter 15. Multitarget activities of Inositol and Inositol Hexakisphosphate (Ivana Vucenik) -- Chapter 16. Integration of Phytochemicals and Phytotherapy into Cancer Precision Medicine (Nadire Özenver and Thomas Efferth) -- Chapter 17. Synergistic Effects of Chinese Herbal Medicine and Biological Networks (Deep Jyoti Bhuyan, Saumya Perera1, Kirandeep Kaur, Muhammad A. Alsherbiny, Mitchell Low, Sai-Wang Seto, Chun-Guang Li, Xian Zhou) -- Chapter 18. Medicinal herbs: its therapeutic use in obstetrics and gynaecology (Irene Orbe, Daniel Paz, Leyre Pejenaute, Andrea Puente, Laura Diaz de Alda, Sandra Yague, Iñaki Lete) -- Chapter 19. Overcoming Antibiotic Resistance: New Perspectives (Matteo Bassetti, Elda Righi).
    Abstract: This volume – for pharmacologists, systems biologists, philosophers and historians of medicine – points to investigate new avenues in pharmacology research, by providing a full assessment of the premises underlying a radical shift in the pharmacology paradigm. The pharmaceutical industry is currently facing unparalleled challenges in developing innovative drugs. While drug-developing scientists in the 1990s mostly welcomed the transformation into a target-based approach, two decades of experience shows that this model is failing to boost both drug discovery and efficiency. Selected targets were often not druggable and with poor disease linkage, leading to either high toxicity or poor efficacy. Therefore, a profound rethinking of the current paradigm is needed. Advances in systems biology are revealing a phenotypic robustness and a network structure that strongly suggest that exquisitely selective compounds, compared with multitarget drugs, may exhibit lower than desired clinical efficacy. This appreciation of the role of polypharmacology has significant implications for tackling the two major sources of attrition in drug development, efficacy and toxicity. Integrating network biology and polypharmacology holds the promise of expanding the current opportunity space for druggable targets.
    Type of Medium: Online Resource
    Pages: XVI, 483 p. 49 illus., 41 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030328573
    Series Statement: Human Perspectives in Health Sciences and Technology, 2
    URL: https://doi.org/10.1007/978-3-030-32857-3
    DOI: 10.1007/978-3-030-32857-3
    DDC: 615
    Language: English
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  • 10
    Online Resource
    Online Resource
    Pharmacology of Potassium Channels (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Human physiology. ; Neurosciences. ; Pharmacology. ; Human Physiology. ; Neuroscience.
    Description / Table of Contents: Comparison of K+ Channel families -- High-resolution structures of K+ channels -- Pharmacological approaches to studying potassium channels -- Cardiac K+ channels and channelopathies -- Cardiac hERG K+ channel as safety and pharmacological target -- Pharmacology of A-type K+ channels -- Kv7 channels and hyperexcitability disorders -- Pharmacological activation of neuronal voltage-gated Kv7/KCNQ/M-channels for potential therapy of epilepsy and pain -- Potassium channels in cancer -- Kir channel molecular physiology, pharmacology and therapeutic implications -- The pharmacology of ATP-sensitive K+ channels (KATP) -- Calcium-activated K+ channels (KCa) and therapeutic implications -- The Pharmacology of two-pore domain potassium channels -- Control of biophysical and pharmacological properties of potassium channels by ancillary subunits -- Peptide toxins targeting KV channels -- Therapeutic antibodies targeting potassium ion channels.
    Abstract: The aim of the present book is to comprehensively review current advances in understanding of genetics, structural biology, pharmacology of potassium channels and their roles in disease as well as to identify current gaps in knowledge. The ultimate goal is to provide a scientific foundation for better understanding of modulatory mechanisms and pharmacology of potassium channels and to use this understanding to drive future drug discovery. This book will be a must-have for academic and industrial scientists interested in physiology, pharmacology, pathology and structure-functional relationships of ion channels. The book will also be helpful for lecturers and students in the college and university classrooms, as well as for anyone interested in the state-of-the art in modern cell biology, physiology and pharmacology. .
    Type of Medium: Online Resource
    Pages: VIII, 545 p. 70 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030840525
    Series Statement: Handbook of Experimental Pharmacology, 267
    URL: https://doi.org/10.1007/978-3-030-84052-5
    DOI: 10.1007/978-3-030-84052-5
    DDC: 615
    Language: English
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  • 11
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    Online Resource
    Nutritional Toxicology (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Nutrition   . ; Food science. ; Pharmacology. ; Nutrition. ; Food Science.
    Description / Table of Contents: 1 Preface -- 2 Effects of Nutrients/nutrition on Toxicants/toxicity -- 3 Effects of Xenobiotics on Nutrition -- 4 Effects of Antinutritional Factors on the Digestibility, Bioavailability and Quality of Protein -- 5 Natural Toxicants Originating from Food/Diet -- 6 Food contaminants -- 7 Food additives -- 8 Food contact materials -- 9 Genetically modified food -- 10 Tolerable upper limits of nutrients -- 11 Risk assessment and Risk-benefit assessment -- 12 Nutrients/Nutrition and Drug Interaction -- 13 Phytochemicals and Health -- 14 Adverse Effects of Phytochemicals.
    Abstract: This book provides a broad overview of the chemicals in food that have the potential to induce adverse health effects. Nutritional Toxicology is an interaction of nutrition, toxicology, biochemistry and food science, etc. Its main research scope involves the effects of nutrients on metabolisms of toxicants and their mechanisms, the interaction of the toxicants and contaminants originated from diet with nutrients and nutrition process, the adverse health outcome of nutrients excess, as well as methodology of research and related food and nutrition regulation process. Also the risk assessment of toxicants and contaminants in foods, and risk benefit assessment of nutrients (dietary supplementation) has become an emerging topic. This book provides novel and provocative insights into the fields of nutrition, food science and toxicology. It also offers a state-of-the-art report on recent discoveries concerning nutritional toxicology and where the field is going. It mainly focuses on advances made over the past 20 years. It will benefit graduate students, researchers and food and nutrition related regulation parties.
    Type of Medium: Online Resource
    Pages: X, 384 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811908729
    URL: https://doi.org/10.1007/978-981-19-0872-9
    DOI: 10.1007/978-981-19-0872-9
    DDC: 615
    Language: English
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  • 12
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    Online Resource
    Network Pharmacology (2021)
    Singapore :Springer Nature Singapore :
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    Keywords: Pharmacology. ; Pharmacy. ; Bioinformatics. ; Pharmacology. ; Pharmacy. ; Bioinformatics.
    Description / Table of Contents: Chapter 1. 'Network Target' Theory and Network Pharmacology -- Chapter 2. Application of Network Pharmacology Based on Artificial Intelligence Algorithm in Drug R & D -- Chapter 3. Commonly used Network Pharmacology Database -- Chapter 4. Commonly used Network Pharmacology Software -- Chapter 5. Network Pharmacology and TCM Modernization Case Studies -- Chapter 6. Network Pharmacology and Modern Drug R & D Cases -- Chapter 7. Drug-based Network Pharmacology Practice Process -- Chapter 8. Disease-based Network Pharmacology Practice Process -- Chapter 9. Drug-disease-based Network Pharmacology Practice Process.
    Abstract: This book introduces “network pharmacology” as an emerging frontier subject of systematic drug research in the era of artificial intelligence and big data. Network Pharmacology is an original subject of fusion system biology, bioinformatics, network science and other related disciplines. It emphasizes on starting from the overall perspective of the system level and biological networks, the analysis of the laws of molecular association between drugs and their treatment objects, reveals the systematic pharmacological mechanisms of drugs, and guides the research and development of new drugs and clinical diagnosis and treatment. After it was proposed, network pharmacology has been paid attention by researchers, and it has been rapidly developed and widely used. In order to systematically reveal the biological basis of diagnosis and treatment in traditional Chinese medicine and modern medicine, we proposed a new concept of "network target" for the first time, which has become the core theory of "network pharmacology". The core principle of a network target is to construct a biological network that can be used to decipher complex diseases. The network is then used as the therapeutic target, to which multicomponent remedies are applied. This book mainly includes four parts: 1) The concept and theory of network pharmacology; 2) Common analysis methods, databases and software in network pharmacological research; 3) Typical cases of traditional Chinese medicine modernization and modern drug research based on network pharmacology; 4) Network pharmacology practice process based on drugs and diseases.
    Type of Medium: Online Resource
    Pages: XVII, 468 p. 163 illus., 119 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811607530
    URL: https://doi.org/10.1007/978-981-16-0753-0
    DOI: 10.1007/978-981-16-0753-0
    DDC: 615
    Language: English
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  • 13
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    Online Resource
    Environment and Female Reproductive Health (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Midwifery. ; Public health. ; Pharmacology. ; Midwifery. ; Public Health.
    Description / Table of Contents: Part I Environmental Harmful Factors -- 1 Introduction to Environmental Harmful Factors -- Part II Female Reproductive Processes and Diseases -- 2 Introduction of Female Reproductive Processes and Reproductive Diseases -- Part III Effects of Environmental Factors on Reproductive Process -- 3 The Influence of Environmental Factors on Ovarian Function, Follicular Genesis, and Oocyte Quality -- 4 Effects of environment and lifestyle factors on premature ovarian failure -- 5 Effects of Environment and Lifestyle Factors on Anovulatory Disorder -- 6 Effects of Cigarette Smoking on Preimplantation Embryo Development -- 7 Toxicical effects of BPDE on dysfunctions of female trophoblast cells -- 8 The Roles of Stress-Induced Immune Response in Female Reproduction -- 9 Effects of Environmental EDCs on Oocyte Quality, Embryo Development and the Outcome in Human IVF Process -- Part IV Effects of Environmental Factors on Reproductive Diseases -- 10 Effects of environmental endocrine-disrupting chemicals on female reproductive health -- 11 Definition and Multiple Factors of Recurrent Spontaneous Abortion -- 12 The Variations of Metabolic Detoxification Enzymes Lead to Recurrent Miscarriage and their Diagnosis Strategy -- Part V Effects of Environmental Factors on Fertility Preservation -- 13 The Effects of Negative Elements in Environment and Cancer on Female Reproductive System.
    Abstract: This book will focus on the harmful effect of environmental toxins on female reproductive health. Reproduction is the basis of the continuation of human beings, and environment is the basis of human survival. However, environmental pollution has become a potential risk factor for human reproductive health, which not only leads to many chronic diseases, but also causes certain harm to reproductive health. Compared to male reproduction, female reproductive process is more complex, the reproductive system is more fragile, and is more vulnerable to be damaged. The aim of this book is to review the research progress, to address the challenges, and to stimulate the development in the direction of environment and female reproductive health.
    Type of Medium: Online Resource
    Pages: XI, 313 p. 13 illus., 10 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789813341876
    Series Statement: Advances in Experimental Medicine and Biology, 1300
    URL: https://doi.org/10.1007/978-981-33-4187-6
    DOI: 10.1007/978-981-33-4187-6
    DDC: 615
    Language: English
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  • 14
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    Online Resource
    Organic Cation Transporters in the Central Nervous System (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Human physiology. ; Molecular biology. ; Pharmacology. ; Human Physiology. ; Molecular Biology.
    Description / Table of Contents: General Overview of Organic Cation Transporters in Brain -- Organic Cation Transporter Expression and Function in the CNS -- Genetic and Epigenetic Regulation of Organic Cation Transporters -- Experimental Methods for Investigating Uptake 2 Processes In Vivo -- Substrates and inhibitors of OCTs and PMAT and therapeutic implications -- Organic Cation Transporters in Brain Histamine Clearance: Physiological and Psychiatric Implications -- Organic Cation Transporters in Brain Catecholamine Homeostasis -- The Interaction of Organic Cation Transporters 1-3 and PMAT with Psychoactive Substances -- Organic Cation Transporters in Psychiatric Disorders -- Organic Cation Transporters and Nongenomic Glucocorticoid Action -- Brain Plasma Membrane Monoamine Transporter in Health and Disease -- Regulation of Neurogenesis by Organic Cation Transporters: Potential Therapeutic Implications -- Organic Cation Transporter (OCT/OCTN) Expression at Brain Barrier Sites: Focus on CNS Drug Delivery.
    Abstract: Rapidly growing interest in the role of organic cation transporters (OCTs) and plasma membrane monoamine transporter (PMAT) in central monoamine homeostasis makes this book especially timely, given its thematic alignment with the role of OCTs and PMAT in CNS. This book discusses latest insights into the field laying an emphasis on health, disease and therapeutics. The chapter, “General Overview of Organic Cation Transporters in Brain”, of this book is available open access under a CC BY 4.0 license at link.springer.com.
    Type of Medium: Online Resource
    Pages: XII, 328 p. 70 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030829841
    Series Statement: Handbook of Experimental Pharmacology, 266
    URL: https://doi.org/10.1007/978-3-030-82984-1
    DOI: 10.1007/978-3-030-82984-1
    DDC: 615
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  • 15
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    Online Resource
    The Carbonic Anhydrases: Current and Emerging Therapeutic Targets (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Clinical biochemistry. ; Pharmacy. ; Pharmacology. ; Medical Biochemistry. ; Pharmacy.
    Description / Table of Contents: Dedication -- Preface.-The carbonic anhydrases in health and disease -- Carbonic anhydrase isozymes as diagnostic biomarkers and therapeutic targets -- Targeting carbonic anhydrases in vascular and pulmonary disease -- Carbonic anhydrase inhibitors in ophthalmology: glaucoma and macular oedema -- Targeting carbonic anhydrase isozymes in the treatment of neurological disorders -- Potential of carbonic anhydrase inhibitors in the treatment of oxidative stress and diabetes -- An overview of carbonic anhydrase-related neoplasms -- The carbonic anhydrase IX interactome and the regulation of cancer progression -- Carbonic anhydrase IX: current and emerging therapies -- Carbonic anhydrase inhibitors: designing isozyme-specific inhibitors as therapeutic agents -- Carbonic anhydrase inhibitors: identifying therapeutic cancer agents through virtual screening -- Targeting carbonic anhydrase IX in tumour imaging and theranostic cancer therapy.
    Abstract: This volume assembles and integrates the wealth of diverse information that is now accumulating in this burgeoning field. The existing and potential therapeutic applications of targeting CA cover a remarkably wide-range of diseases and disorders and have generated increasing and extensive interest in recent years. Its inter-disciplinary approach embraces both the most up-to-date therapeutic application of CA-targeting and the latest research data that will provide a platform for the development of novel applications. The interested audience comprises scientists and clinicians from many relevant disciplines within science and medicine.
    Type of Medium: Online Resource
    Pages: XII, 288 p. 38 illus., 22 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030795115
    Series Statement: Progress in Drug Research, 75
    URL: https://doi.org/10.1007/978-3-030-79511-5
    DOI: 10.1007/978-3-030-79511-5
    DDC: 615
    Language: English
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  • 16
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    Online Resource
    Pharmacology of the WNT Signaling System (2021)
    Cham :Springer International Publishing :
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    Keywords: Pharmacology. ; Physiology. ; Oncology. ; Neurosciences. ; Developmental biology. ; Pharmacology. ; Physiology. ; Oncology. ; Neuroscience. ; Developmental Biology and Stem Cells.
    Description / Table of Contents: Pharmacological thinking in WNT signaling -- Controlling WNT Signaling Specificity and implications for targeting WNTs pharmacologically -- WNTs on exosomes -- Strategies to target LRPs in WNT signaling -- Targeting the receptor tyrosine kinase ROR1 by small molecules -- Assessing WNT binding and Frizzled activation employing genetically encoded, biophysical sensors -- Disheveled proteins as crucial mediators of WNT signaling -- Destruction complex and regulation of CTNNB1 -- Strategies to therapeutically target WNT/PCP like signaling in disease -- Mining natural compounds to target WNT signaling - from mushrooms to corals -- FZD7 as a therapeutic target in intestinal cancer -- Targeting oncogenic WNT signaling with WNT derived peptides -- Targeting WNT signaling in lung pathology -- The role of WNT signaling in osteoarthritis and the therapeutic potential of its pharmacological targeting -- WNT signaling in Alzheimers disease and other neurodegenerative disorders - opportunities for therapy? -- Targeting WNT signaling as a risk.
    Abstract: This book reflects the state of the art of our understanding of the WNT signaling system, which comprises a network of signaling pathways initiated by the secreted WNT lipoglycoproteins, which are crucial for embryonal development, stem cell regulation, tissue homeostasis and repair. Dysfunction of this evolutionarily conserved signaling system leads to many diseases including developmental disorders, diverse forms of cancer, fibrosis, neurodegenerative disease and many more. The WNT signaling system is built upon 19 mammalian, secreted WNT lipoglycoproteins that interact with a plethora of distinct receptors, such as the G protein-coupled receptors called Frizzleds (FZD1-10), LDL receptor-like proteins (LRP5/6), receptor tyrosine kinases (ROR1, 2, RYK and PTK7). In addition, WNT pathways are tightly regulated by many secreted and cell-intrinsic negative regulators, such as soluble FZD-related proteins (SFRPs), Dickkopfs (DKKs), WNT-inhibitory proteins, TIKI, RNF43 and more. Understanding the basic mechanism in terms of receptor-ligand interaction, receptor selectivity, signal initiation and desensitization remain poorly understood, even though substantial advances have been made the recent years. Due to the involvement of the WNT signaling system in human disease, it appears obvious to target diverse branches pharmacologically and therapeutically. However, given the complexity of the system and its importance for stem cell regulation and tissue maintenance, therapy comes with obvious risks for severe side effects. The field is addressing the challenge to identify suitable targets and selective compounds for therapy allowing disease-selective therapeutic effects and balancing unwanted side effects. This book summarizes the current understanding of the basic and applied pharmacology in the WNT signaling system and bridges disciplines such as pharmacology, physiology, neurosciences, oncology and drug development.
    Type of Medium: Online Resource
    Pages: VIII, 422 p. 70 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030854997
    Series Statement: Handbook of Experimental Pharmacology, 269
    URL: https://doi.org/10.1007/978-3-030-85499-7
    DOI: 10.1007/978-3-030-85499-7
    DDC: 615
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  • 17
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    Online Resource
    The Art of Carbohydrate Analysis (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Chemistry, Organic. ; Food science. ; Biotechnology. ; Pharmacology. ; Organic Chemistry. ; Food Science. ; Biotechnology.
    Description / Table of Contents: Chapter 1 The World of Carbohydrates -- Chapter 2 Basic Knowledge of Glycobiology -- Chapter 3 Carbohydrates involved in Diseases -- Chapter 4 Detection of Carbohydrate by Colorimetric Methods -- Chapter 5. Analytical Techniques to Study Carbohydrates -- Chapter 6 Monosaccharide Composition Analysis -- Chapter 7 Carbohydrate Analysis of Glycoconjugates -- Chapter 8 Structural Characterization of Released Glycans -- Chapter 9 Analysis of Sialic Acids -- Chapter 10 Carbohydrate Microarray Technology -- Chapter 11 Analysis of Carbohydrates by Mass Spectrometry -- Chapter 12 Analysis of Carbohydrates by Nuclear Magnetic -- Chapter 13 Glycobioinformatics -- Chapter 14 Concluding Remarks. .
    Abstract: The growing importance of glycobiology and carbohydrate chemistry in modern biotechnology and the pharmaceutical industry makes accurate carbohydrate analysis indispensable. This book provides the principles and protocols of various fundamental carbohydrate analysis methods. Choice of method is entirely dependent upon the type of material being investigated (biological samples, food products, etc.), and the level of structural detail required, i.e. sugar content, compositional analysis, linkages between the sugar components, or the total chemical structure of a given molecule. Full structural characterization of carbohydrate chains requires significant time, resources, and skill in several methods of analysis; no single technique can address all glycan analysis needs. This book summarizes several existing analytical techniques (both chemical and physical) in an introductory volume designed for the non-expert researcher or novice scientist. While background in carbohydrate chemistry is assumed, all information necessary to understanding the described techniques is addressed in the text.
    Type of Medium: Online Resource
    Pages: XXV, 350 p. 117 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030777913
    Series Statement: Techniques in Life Science and Biomedicine for the Non-Expert,
    URL: https://doi.org/10.1007/978-3-030-77791-3
    DOI: 10.1007/978-3-030-77791-3
    DDC: 615
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  • 18
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    Online Resource
    Polypharmacology : Principles and Methodologies (2022)
    Cham :Springer International Publishing :
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    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Drug delivery systems. ; Neuropharmacology. ; Pharmacology. ; Pharmaceutics. ; Drug Delivery. ; Neuropharmacology.
    Description / Table of Contents: PART I. Polypharmacology as a New Branch of Pharmacology: Concept and Principles -- Basics of Polypharmacology -- Polypharmacology in Clinical Applications: Multitarget Multidrug-combination (MTMD-C) -- Polypharmacology in Clinical Applications: Multitarget Multidrug-single-formulation (MTMD-SF) -- Polypharmacology in Clinical Applications: Multitarget Single-drug (MTSD) -- Polypharmacology in Drug Discovery: Designed Epigenetic MTSD and Small-molecule MTSD -- Anti-cancer Polypharmacology -- Cardiovascular Polypharmacology -- Neuronal Polypharmacology -- Pulmonary Polypharmacology -- Polypharmacology of Metabolic Disease -- Polypharmacology of Infectious Disease -- Polypharmacology of Inflammation -- Anti-psychotics Polypharmacology -- Anti-aging Polypharmacology -- Polypharmacology in Drug Repurposing -- Polypharmacology and Unintended Drug Promiscuity -- Polypharmacology Pharmacokinetics -- The Future of Polypharmacology -- PART II. Polypharmacology in New Drug Development: Strategies and Protocols -- Designed MTSD Discovery Process -- Designed MTSD Discovery Strategies -- Designed MTSD Discovery Technologies -- Designed MTSD Discovery Databases -- Designed MTSD Target Deconvolution.-Designed MTSD Target Validation -- Designed MTSD Lead Identification and Optimization -- Designed MTSD Discovery Protocols -- Natural Products in MTSD Discovery -- Polypharmacology Procedures for Drug Repurposing -- Polypharmacology Procedures for Drug Promiscuity Discovery.
    Abstract: There is a growing interest in unmet needs for the development of a new discipline in drug discovery and in university education on Polypharmacology. However, there has not been a book with the comprehensive compilation of basic knowledge and advanced methodology on Polypharmacology. This book aims to meet the needs of making Polypharmacology a new sub-discipline of Pharmacology, not only being a hot area of pharmacological research and education but also a new paradigm for drug discovery. It contains the contents covering the entire scope of Polypharmacology including systemic in-depth exposition of basic knowledge, novel concepts, innovative technologies, and translational and clinical applications by showcasing state-of-the-art strategies and step-by-step instructions of cutting-edge methods. The contents of Polypharmacology targets broad readerships including scientists in pharmacology research and drug development, and university teachers and graduates in medical school or school of pharmacy. Rich in illustrations and tables to showcase readers for better understanding the concepts and technologies related to Polypharmacology; Provides comprehensive, systemic, holistic, and explicit explanations and discussion of the fundamental knowledge, background information, conceptual evolution, and updated methodology, as well as in-depth mechanisms behind the knowledge and methodology of Polypharmacology; Main emphasis on rationally designed Polypharmacology or “multi-target, single-drug (MTD)” pharmacology, which represents the major future direction of Polypharmacology and Pharmacology; Describes the clinical applications of Polypharmacology to various human diseases in the clinical and preclinical settings; Contains a wide collection of the state-of-the-art Polypharmacology technologies applicable to the designed MTD discovery and the step-by-step descriptions of drug discovery process applying Polypharmacology principles and methodologies.
    Type of Medium: Online Resource
    Pages: XXV, 856 p. 12 illus., 9 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031049989
    URL: https://doi.org/10.1007/978-3-031-04998-9
    DOI: 10.1007/978-3-031-04998-9
    DDC: 615
    Language: English
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  • 19
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    Online Resource
    Advanced Drug Delivery Strategies for Targeting Chronic Inflammatory Lung Diseases (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Nanobiotechnology. ; Biomedical engineering. ; Drug delivery systems. ; Pharmaceutical chemistry. ; Pharmacology. ; Nanobiotechnology. ; Biomedical Engineering and Bioengineering. ; Drug Delivery. ; Pharmaceutics.
    Description / Table of Contents: Chapter 1. An introduction to respiratory diseases and an emerging need for efficient drug delivery systems -- Chapter 2. Inflammatory respiratory diseases: Correlation between Lung cancer and CoVid-19 -- Chapter 3. Advancements in translational respiratory research using nanotechnology -- Chapter 4. Chemical moieties as advanced therapeutics for targeting respiratory disorders -- Chapter 5. Phytochemicals and their nanoformulations targeted for pulmonary diseases -- Chapter 6. Nanocarriers: an advanced and highly effective approach for targeting chronic lung diseases -- Chapter 7. Vesicular drug delivery systems in respiratory diseases -- Chapter 8. Nanoparticles in chronic respiratory diseases -- Chapter 9. Applications of nanotechnology in pulmonary disease diagnosis -- Chapter 10. Nanotechnology in pulmonary disease diagnosis -- Chapter 11. Recent trends in Nanomedicine for diagnosis and treatment of pulmonary diseases -- Chapter 12. Strategies for enhanced drug targeting to inflamed lungs: Novel perspectives -- Chapter 13. Solid-Lipid Nanocarriers (SLN’s) based drug delivery for treating various pulmonary diseases -- Chapter 14. Microparticles, microspheres and microemulsions as pulmonary drug delivery systems for the treatment of respiratory diseases -- Chapter 15. Microparticles, microspheres and microemulsions in respiratory diseases -- Chapter 16. Advanced drug delivery systems targeting the immune system at cellular level in chronic respiratory diseases -- Chapter 17. Targeted Micellar Systems for Pulmonary Disease Intervention -- Chapter 18. Polymeric and inorganic nanoparticles targeting chronic respiratory diseases -- Chapter 19. Mucoadhesive drug delivery system in chronic respiratory diseases -- Chapter 20. Liposomal Drug Delivery: Therapeutic Applications in Chronic Respiratory Diseases -- Chapter 21. Biologics and vaccines for nasal and pulmonary drug delivery -- Chapter 22. Drug delivery systems for respiratory infections -- Chapter 23. Cell and Gene Therapies for Chronic Inflammatory Lung Diseases - Emerging Technological Trends and Advancements in Respiratory Medicine -- Chapter 24. Targeting biofilms in respiratory diseases using novel drug delivery systems -- Chapter 25. Advanced nanomaterials for drug delivery in chronic respiratory disorders -- Chapter 26. Emerging technological trends and advancements in respiratory medicine -- Chapter 27. Pulmonary pharmacokinetics and Biophysics -- Chapter 28. Clinical trials on novel advanced drugs for chronic respiratory disorders.
    Abstract: This book describes the growing clinical and healthcare relevance of nano-therapeutics in treating respiratory diseases. It begins with a brief introduction on the different types of nanoparticles in respiratory disease conditions. It further discusses the current trends in understanding the disease pathology using different in vitro and in vivo models, which are important towards the onsite clinical applications and development of new therapeutics. The book includes exciting topics such as formulation of these nanoparticles, targeting various organelles etc. It also describes the future prospects and challenges in the field. Different chapters are written by researchers actively working in the area of pulmonary diseases. This book is designed to address the requirements of both beginners and specialized scientists involved in pulmonary research. The contents include basic concepts followed by advanced state-of-art monitoring and treatment of diseases. The book is meant for researchers and industry experts in nanotechnology, pharmaceutical sciences and drug design.
    Type of Medium: Online Resource
    Pages: X, 655 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811643927
    URL: https://doi.org/10.1007/978-981-16-4392-7
    DOI: 10.1007/978-981-16-4392-7
    DDC: 615
    Language: English
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  • 20
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    Online Resource
    Data Monitoring Committees (DMCs) : Past, Present, and Future (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Medical sciences. ; Drug development. ; Medicine Research. ; Biology Research. ; Pharmaceutical chemistry. ; Biometry. ; Toxicology. ; Pharmacology. ; Preclinical Research. ; Biomedical Research. ; Pharmaceutics. ; Biostatistics. ; Medical Toxicology.
    Description / Table of Contents: Introduction-.What is a DMC?-. Is a DMC required?-. Who is On the DMC?-. What are the Legal and Ethical Aspects of DMC?-. How does the DMC work with SDAC and Sponsor and External Groups ? -- What Does a DMC Meeting Look Like -- What data is used for DMC outputs and who programs? -- What is Included in DMC Outputs? -- What does the DMC final DMC outputs look like and how is it delivered? -- What Types of Safety Outputs Does the DMC Receive? -- What types of efficacy outputs does the DMC receive? -- What types of other outputs does the DMC receive? -- What About In-Between DMC Meetings -- What types of formal interim analyses does the DMC review? -- What does the paperwork from meetings look like? -- How does the DMC assess risk-benefit for their decision making? -- What are some examples? -- Conclusions.
    Abstract: This book provides an overview of Data Monitoring Committees - what was done in the past, what is currently being done, and thoughts on improvements for the future. Previous works focused primarily on large cardiovascular studies (where DMCs originated more than 30 years ago) but updated references are needed that discuss smaller, more flexible studies in areas such as oncology. The authors have attended ~800 DMC meetings from ~200 distinct studies across all areas of clinical studies (oncology, rheumatology, rare diseases, cardiology, immunology, etc.) This wide range of expertise will be used, as well as the expertise that comes from working with virtually every large biotech/pharma and CRO for DMC work. The reader of the book will know when DMCs are needed or helpful, how to form the DMC, how to work with external CROs and with sponsor teams and the DMC to create needed DMC outputs, how the DMC meetings are conducted, and - especially for DMC members - what are considerations within the Closed Session to review safety/efficacy outputs to assess risk/benefit to make appropriate recommendations that protect the patient safety and trial integrity. This is a practical hands-on book on how to decide if a DMC is necessary, how to form the DMC, how to smoothly create the necessary materials for the DMC and have smooth running DMC meetings. There is no specialized training in school about how DMCs work - frequently people may have been in industry for many years without ever needing to work with a DMC. This book is the helpful reference for those new to these DMCs. The DMC work is critical to be correctly implemented as the implications of it are so great. This book provides the following: Thorough instructions on the steps needed to form and implement a Data Monitoring Committee for clinical trial evaluation; Includes practical and hands-on information on DMC implementation; Discusses a wide range of clinical trial – by phase and therapeutic area.
    Type of Medium: Online Resource
    Pages: XII, 111 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031287602
    URL: https://doi.org/10.1007/978-3-031-28760-2
    DOI: 10.1007/978-3-031-28760-2
    DDC: 615
    Language: English
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  • 21
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    Macrophage Targeted Delivery Systems : Basic Concepts and Therapeutic Applications (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Cytology. ; Toxicology. ; Immunology. ; Pharmacology. ; Pharmaceutics. ; Cell Biology. ; Toxicology. ; Immunology.
    Description / Table of Contents: Part I Anatomy, Physiology and Pharmacology of Macrophages -- Introduction to Anatomy and Physiology of Macrophages from Drug Delivery Perspective -- Introduction to Pharmacology of Macrophages from Drug Delivery Perspective -- Mechanisms and Ways of Macrophage Delivery -- Macrophage Associated Disorders: Pathophysiology, Treatment Challenges and Possible Solutions -- Understanding Macrophage Associated Diseases and Applications of Nano Drug Delivery Systems -- Part II Polymeric Nanoparticles for Macrophage Targeting -- Targeting of Macrophages: Basic and therapeutic Role of Polymeric Nanoparticles -- Polymeric Nanoparticles Based Drug and Gene Delivery to Macrophages -- Surface Modification of Nanoparticles for Macrophage Targeting -- Part III Lipid Nanoparticles for Macrophage Targeting -- Liposomes as Delivery System for Macrophage Targeting -- Solid Lipid Nanoparticles Based Drug and Gene Delivery to Macrophages -- In vivo Fate of Colloidal Carriers Undergoing Macrophage Targeting -- Nanoparticle-based Theranostics for Macrophage-associated Diseases -- Part IV Targeting Macrophages for Treatment of Various Diseases -- Tumor Associated Macrophages as Therapeutic Target for Drug/immune Therapy of Cancer -- Macrophage Targeting for Therapy of Autoimmune Diseases -- Macrophage Targeting for Therapy of Cardiovascular Diseases (CVD) -- Macrophage targeting for therapy of intracellular infections -- Targeting Drugs and Nucleic Acids to Macrophages for Therapy of Inflammatory Diseases -- Macrophage Targeted Chemotherapy for Tuberculosis and other Respiratory Disease. -- Part V Specific Formulations and Clinical Trials on Macrophage Targeted Delivery -- Nano- and Microparticles Based Dry Powder Inhalers for Pulmonary Macrophage Drug Delivery -- Recent Trends in Clinical Studies on Macrophage Targeted Delivery -- Future Directions and Challenges in Macrophage Targeting. .
    Abstract: The proposed book is envisioned for the nascent and entry-level researchers who are interested to work in the field of drug delivery and its applications specifically for macrophage targeting. Macrophages have gained substantial attention as therapeutic targets for drug delivery considering their major role in health and regulation of diseases. Macrophage-targeted therapeutics have now added significant value to the lives and quality of life of patients, without undue adverse effects in multiple disease settings. We anticipate examining and integrating the role of macrophages in the instigation and advancement of various diseases. The major focus of the book is on recent advancements in various targeting strategies using delivery systems or nanocarriers followed by application of these nanocarriers for the treatment of macrophage associated disorders. Macrophage Targeted Delivery Systems is primarily targeted to Pharmaceutical Industry & Academia, Medical & Pharmaceutical Professionals, Undergraduate & Post graduate students and Research Scholars, Ph.D, post docs working in the field of medical and pharmaceutical sciences.
    Type of Medium: Online Resource
    Pages: XVIII, 556 p. 76 illus., 73 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030841645
    URL: https://doi.org/10.1007/978-3-030-84164-5
    DOI: 10.1007/978-3-030-84164-5
    DDC: 615
    Language: English
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  • 22
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    Online Resource
    Synbiotics for the Management of Cancer (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Cancer. ; Cancer Treatment. ; Pharmacology. ; Cancers. ; Cancer Therapy.
    Description / Table of Contents: Chapter 1_Introduction to Cancer -- Chapter 2_Effect of anticancer treatment approches on gut microbiota -- Chapter 3_Synbiotic: A promising approach for the treatment of cancer -- Chapter 4_Correlation between ROS and Synbiotics for effective treatment of cancer -- Chapter 5_Influence of synbiotics on inflammation and immune microenvironment for the treatment of cancer -- Chapter 6_Synbiotics in colorectal cancer -- Chapter 7_Synbiotics in cervical cancer -- Chapter 8_Synbiotics in prostate cancer -- Chapter 9_Synbiotics in gastric cancer -- Chapter 10_Synbiotics in lung cancer -- Chapter 11_Synbiotics in small cell pancretatic cancer -- Chapter 12_Synbiotics in breast cancer -- Chapter 13_Synbiotics in hepatocellular carcinoma -- Chapter 14_Synbiotics in ovarian cancer -- Chapter 15_Regulatory issues of synbiotics in cancer.
    Abstract: This book illustrates the significance of probiotics and prebiotics for the management of various types of cancers. The up-to-date chapters provide recent information about the effect of anticancer treatment approaches on gut microbiota, the correlation between ROS and synbiotics for effective cancer treatment, and the influence of synbiotics on inflammation and immune microenvironment for cancer treatment. It also describes the regulatory issues about synbiotics in the management of cancer. This book is an essential resource for scientists working in the field of cancer, pharmaceutical & clinical sciences, and cancer clinicians. This book is also very useful for undergraduate and postgraduate students of Pharmacy and Biotechnology and medical researchers, mainly working in microbiology, immunology, and cancer biology.
    Type of Medium: Online Resource
    Pages: XVII, 340 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811975509
    URL: https://doi.org/10.1007/978-981-19-7550-9
    DOI: 10.1007/978-981-19-7550-9
    DDC: 615
    Language: English
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  • 23
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    Online Resource
    Recent Advances in Pharmaceutical Innovation and Research (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Drug delivery systems. ; Nanobiotechnology. ; Pharmacology. ; Pharmaceutics. ; Drug Delivery. ; Nanobiotechnology.
    Description / Table of Contents: Part 1. Pharmaceutical Innovation and Research -- Chapter 1. Innovation in stabilization of biopharmaceuticals -- Chapter 2. Concepts in pharmacogenomics: tools and applications -- Chapter 3. Pharmacogenetics–a new approach for the selection of the right drug -- Chapter 4. Meeting the unmet challenges of pharmaceutical research using artificial intelligence -- Chapter 5. Pharmaceutical innovation and research in ayurved -- Chapter 6. Ayurveda intervention in perimenopausal syndrome -- Part 2. Drug Discovery and Development -- Chapter 7. Innovative strategies in drug discovery and pharmacoinformatics -- Chapter 8. Advances in peptide synthesis -- Chapter 9. Peptidomimetics in Medicinal Chemistry: The Art of Transforming Peptides to Drugs -- Chapter 10. Diverse Pharmacological Activities of 4-aminoquinoline and its Derivatives -- Chapter 11. Thiourea catalysts for synthesis of active pharmaceutical ingredients -- Chapter 12. The Chemistry and Pharmacology of Mandarin Orange -- Chapter 13. Recent progress in the pharmacology of phytoestrogens: emerging neuromodulators for treating anxiety and depression -- Chapter 14. Next-generation cell-based therapies to combat metastaticbrain tumor -- Chapter 15. Pharmacokinetics and Pharmacodynamics: Fundamentals and Role(s) in Drug Discovery and Development -- Chapter 16. An update on pharmacokinetic models -- Chapter 17. Pharmacodynamics: Basics and Applications in Drug Research -- Part 3. Drug Delivery and Nanotechnology -- Chapter 18. Technological innovations in pharmaceutical drug nanocrystals -- Chapter 19. Fixed Dose Combinations: Innovations and Research -- Chapter 20. Significance of Intranasal Drug Delivery Systems: Recent Trends and Clinical Investigations in Brain Disorders -- Chapter 21. Current challenges and nanotechnology-based pharmaceutical approaches for the treatment and control of visceral leishmaniasis -- Chapter 22. Polymeric Nanoparticles-based Drug Delivery Systems for Anticancer Therapy. Chapter 23. Carbon nanotubes: a review of toxicity and applicability in biomedical applications -- Chapter 24. Recent trends in topical herbal nanotherapeutics for psoriasis -- Part 4. Pharmaceutical Microbiology -- Chapter 25. Antibiotics: past, present, future, and clinical pipeline -- Chapter 26. Innovative strategies to tackle antimicrobial resistance -- Chapter 27. Molecular and mechanistic insights of yeast flocculation -- Chapter 28. Management of hepatitis virus C: current and future treatments -- Chapter 29. Tuberculosis: experimental models, innovations and challenges -- Chapter 30. Targeting outer membrane to tackle multi-drug resistant bacterial pathogens -- Chapter 31. Diphtheria-A Paradigmatic Vaccine Preventable Toxigenic Disease with Changing Epidemiology -- Chapter 32. Emerging and re-emerging infections: an overview.
    Abstract: This book covers several important aspects of pharmaceutical research and innovations. It presents important topics on drug delivery, novel microsponge, nanocrystals, polymeric nanoparticles, peptide synthesis, biopharmaceuticals, pharmacodynamics, yeast flocculation, neuromodulators, innovative drug discovery, pharmacoinformatics, aminoquinoline, thiourea crystals for API synthesis, FDCs and formulations research, ayurveda and natural products, and innovations to militate anti-microbial resistance (AMR). A chapter is devoted to the applications of Artificial Intelligence and Machine Learning in diverse sectors of the pharmaceutical industry, including drug discovery and development, drug repurposing, and improving pharmaceutical productivity. The book also reviews the role of pharmacogenomics and pharmacogenetics in drug development and precision medicine. Further, the book presents an updated summary of recent advances in the fields of nanomedicines and nano-based drug delivery systems. This book is useful to pharmaceutical sciences students, researchers, educators, and professionals in the pharmaceutical industry to understand the intricacies of new drug research and innovations.
    Type of Medium: Online Resource
    Pages: XXI, 770 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819923021
    URL: https://doi.org/10.1007/978-981-99-2302-1
    DOI: 10.1007/978-981-99-2302-1
    DDC: 615
    Language: English
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  • 24
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    Online Resource
    Block Co-polymeric Nanocarriers: Design, Concept, and Therapeutic Applications (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Nanobiotechnology. ; Drug delivery systems. ; Pharmacology. ; Nanobiotechnology. ; Drug Delivery.
    Description / Table of Contents: Ch 1 Introduction to block co-polymers -- Ch 2 Role of block co-polymers in drug delivery -- Ch 3 Role of block co-polymers in enhancement of poor solubility of drugs -- Ch 4 Synthesis and Self–assembly of block copolymers -- Ch 5 Role of block co-polymers in treatment of brain disorders -- Ch 6 Role of block co-polymers in treatment of neurodegenerative disorders -- Ch 7 Role of block co-polymers in colon cancer -- Ch 8 Role of block co-polymers in lung cancer -- Ch 9 Role of block co-polymers in IBD -- Ch 10 Role of block co-polymers in vaccine -- Ch 11 Role of block co-polymers in treatment of GIT disorders -- Ch 12 Role of block co-polymers in topical drug delivery -- Ch 13 Role of block co-polymers in targeted drug delivery -- Ch 14 Role of block co-polymers in ocular drug delivery -- Ch 15 Role of block co-polymeric micelles in drug delivery -- Ch 16 Applications of block co-polymers as Stimuli Responsive Copolymers -- Ch 17 Patented block co-polymers for various Therapeutics Applications.
    Abstract: This book focuses on current advancements in the field of block copolymers and covers design, concept, and various therapeutic applications in the drug delivery. It also reviews the use of block copolymers in drug delivery applications from the development of sustained release products to smart polymeric delivery systems such as stimuli-responsive polymeric systems, for example, thermosensitive, redox-sensitive, photo-sensitive, and enzyme-sensitive. The book further discusses the nano assemblies from amphiphilic block copolymers as nanomedicine platforms for diagnosis and therapy due to their relatively small size, high drug loading capacity, controlled drug release, in vivo stability, and prolonged blood circulation. The chapters also review the various patents and ongoing clinical trials on the applications, covering several important new concepts and findings in the field of block copolymers. The book is aimed at researchers, academicians, and industrial scientists involved in the development of drug-delivery systems based on polymers.
    Type of Medium: Online Resource
    Pages: XVII, 429 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819969173
    URL: https://doi.org/10.1007/978-981-99-6917-3
    DOI: 10.1007/978-981-99-6917-3
    DDC: 615
    Language: English
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  • 25
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    Online Resource
    Pharmacology of Immunotherapeutic Drugs (2020)
    Cham :Springer International Publishing :
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    Keywords: Pharmacology. ; Immunology. ; Pharmacology. ; Immunology.
    Description / Table of Contents: Preface Chapter 1: Overview of the Immune System and its Pharmacological Targets -- Chapter 2: Modulation of the Innate Immune System -- Chapter 3: Modulation of the Adaptive Immune System -- Chapter 4: Respiratory Disorders of the Immune System and their Pharmacological Treatment -- Chapter 5: Inflammation of the Skin and its therapeutic topics -- Chapter 6: Inflammatory Diseases of the Gastrointestinal Tract and Pharmacological Treatments -- Chapter 7: Mechanisms of Autoimmunity and Pharmacologic Treatments -- Chapter 8: Transplantation: Immunologic Principles and Pharmacologic Agents -- Chapter 9: Immunopathogenesis, Immunization, and Treatment of Infectious Diseases -- Chapter 10: Cancer Immunotherapy.
    Abstract: Medicine has entered a golden age in which therapeutic agents are becoming widely available due to advances in basic science and technology. As such, many drugs have been developed that target inflammatory processes and/or the immune system. This book is intended for health professionals examining the modulation of inflammation by immunotherapeutic drugs. The immune system fills the primordial role of host defense and resistance to infections with pathogenic microorganisms. Several hematopoietic-derived cells constituting the innate and adaptive immune systems cooperate to provide barriers for microbial colonization and/or promote pathogen destruction within the host. Conversely, many immune cells are also involved in the pathogenesis and propagation of chronic inflammatory diseases. The beginning of this book details various components of the immune system including the cell types, lymphoid tissues, soluble cytokines and surface molecules that are essential for host defense. Breakdowns in immune tolerance, or dysregulated immune responses to antigens derived from self tissues or innocuous sources, can lead to the development of autoimmunity or chronic inflammatory diseases. Pathophysiologic roles for the immune system are detailed in corresponding chapters on autoimmunity, epithelial surfaces (lungs, skin, intestine), and transplantation, with special emphasis placed on immunotherapeutic drug targets. The last section of the book focuses on treatments that stimulate our immune system to specifically target and fight infectious diseases and cancer. In each chapter, the medications used to treat various diseases/conditions in terms of their mechanism of action and other pharmacologic properties are discussed in detail. Chapters begin with a table showing drug names and classifications. The importance of basic science and clinical trials cannot be understated in the context of drug development. As such, the discovery of certain medications that had a lasting impact in medicine and pharmacy are highlighted in chapter subsections named “Bench to Bedside.” Several clinical applications of immunotherapeutic drugs are described within end-of -chapter case studies including practice questions. The Pharmacology of Immunotherapeutic Drugs is a reference for immunologists and clinicians (medical doctors, pharmacists, nurses) examining the modulation of inflammatory processes by a variety of medications targeting the cells and mediators of our immune system.
    Type of Medium: Online Resource
    Pages: XIX, 399 p. 118 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030199227
    URL: https://doi.org/10.1007/978-3-030-19922-7
    DOI: 10.1007/978-3-030-19922-7
    DDC: 615
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  • 26
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    Online Resource
    Biomedical Applications and Toxicity of Nanomaterials (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Nanobiotechnology. ; Nanomedicine. ; Pharmacology. ; Nanobiotechnology. ; Nanomedicine and Nanotoxicology.
    Description / Table of Contents: Chapter 1. Macroporous cryogel-based systems for water treatment applications and Safety: nanocomposite-based cryogels and bacteria-based bioreactors -- Chapter 2. One dimensional Semiconducting Nanomaterials: Toxicity and Clinical Applications -- Chapter 3. Prospects of Safe use of Nanomaterials in Biomedicalapplications -- Chapter 4. Hyaluronic acid-based nanotechnologies for delivery and treatment -- Chapter 5. Theranostics nanomaterials for safe cancer treatment -- Chapter 6. Cardiovascular safety assessment of new chemical entities: current perspective and emerging technologies -- Chapter 7. Toxicology of pharmaceutical products during drug development -- Chapter 8. Safety and Risk assessment of food items -- Chapter 9. Non toxic Natural products as regulators of tumour suppressor gene function -- Chapter 10. Advancements in the safety of Plant medicine: Back to nature -- Chapter 11. Chemicals and their interaction in the aquaculture system -- Chapter 12. Zebrafish as a biomedical model to define developmental origins of chemical toxicity -- Chapter 13. Green synthesis of non toxic nanoparticles -- Chapter 14. Synthesis, characterisation and safety of titanium oxide nanoparticles -- Chapter 15. Characterisation of non toxic nanomaterials for biological applications -- Chapter 16. Toxicity assessment of nanoparticle -- Chapter 17. Safety of nanoparticles: emphasis on antimicrobial properties -- Chapter 18. Quantum dots for imaging and its safety -- Chapter 19. Genotoxicity evaluation of nanosized materia -- Chapter 20. Scaffoldmaterials and toxicity -- Chapter 21 Biological Safety and Cellular interactions of nanoparticles -- Chapter 22. Role of artificial intelligence in the toxicity prediction of drugs -- Chapter 23. Chemicals and rodent models for the safety study of alzheimer’s disease -- Chapter 24. Mitochondria-targeted liposomal delivery in Parkinson's disease: safety concerns -- Chapter 25. Routes of Nano-drug Administration and Nano-based drug delivery system and toxicity -- Chapter 26. Green Synthesised silver nanoparticles phytotoxicity and applications in agriculture: An overview -- Chapter 27 status of safety concerns of microplastic detection strategies -- Chapter 28. Impact of insecticides on man and environment.
    Abstract: This book covers the recent trends on the biological applications of nanomaterials, methods for their preparation, and techniques for their characterization. Further, the book examines the fundamentals of nanotoxicity, methods to assess the toxicity of engineered nanomaterials, approaches to reduce toxicity during synthesis. It also provides an overview of the state of the art in the application of Artificial intelligence-based methodologies for evaluation of toxicity of drugs and nanoparticles. The book further discusses nanocarrier design, routes of various nanoparticle administration, nano based drug delivery systems, and the toxicity challenges associated with each drug delivery method. It presents the latest advances in the interaction of nanoparticles with the cellular environment and assess nanotoxicity of these engineered nanoparticles. The book also explores the comparative and mechanistic genotoxicity assessment of the nanomaterials. This book is useful source of information for industrial practitioners, policy makers, and other professionals in the fields of toxicology, medicine, pharmacology, food, and drugs.
    Type of Medium: Online Resource
    Pages: XVIII, 768 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811978340
    URL: https://doi.org/10.1007/978-981-19-7834-0
    DOI: 10.1007/978-981-19-7834-0
    DDC: 615
    Language: English
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  • 27
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    Online Resource
    Pharmacology of Drug Stereoisomers (2022)
    Singapore :Springer Nature Singapore :
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    Keywords: Pharmacology. ; Medicinal chemistry. ; Pharmaceutical chemistry. ; Biotechnology. ; Biochemical engineering. ; Pharmacology. ; Medicinal Chemistry. ; Pharmaceutics. ; Biotechnology. ; Bioprocess Engineering.
    Description / Table of Contents: Preface -- General principles of chirality -- Quantitative methods of analysing chirality drugs - Chirality and pharmacokinetics -- Drugs regulating the function of peripheral nervous system -- In silico search for chiral drug compounds.
    Abstract: The book is devoted to an important aspect of pharmacology and pharmaceutical chemistry, i.e. the significance of stereoisomerism of drugs for their biological effect from the point of view of their pharmacokinetics, pharmacodynamics and toxicology. The authors review the landmarks in the development of stereochemistry and stereopharmacology. Present-day IUPAC terminology is discussed; general issues of stereoisomerism are considered including separation of racemic mixtures and asymmetric synthesis of isomers, methods of quantifying the isomers of a drug in biological material. The authors put special emphasis on general problems of the influence of stereoisomerism on pharmacological and adverse effects of drugs. A classification of drugs based on stereochemical properties of their isomers is proposed. Possibilities of interaction of stereoisomers in racemic mixtures are discussed. A considerable portion of the book is devoted to pharmacological action of the main groups of drugs whose structure includes asymmetric atoms (that is, drugs with several isomers). Detailed attention is paid to advisability of developing single isomer drugs and to the specifics of their study at the stage of preclinical and clinical trials.
    Type of Medium: Online Resource
    Pages: XI, 207 p. 174 illus., 6 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811923203
    Series Statement: Progress in Drug Research, 76
    URL: https://doi.org/10.1007/978-981-19-2320-3
    DOI: 10.1007/978-981-19-2320-3
    DDC: 615
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  • 28
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    Online Resource
    Rabies and Rabies Vaccines (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Virology. ; Immunology. ; Pharmacology. ; Virology. ; Immunology.
    Description / Table of Contents: Rabies Life Cycle, Transmission and Pathogenesis -- History of Rabies and Rabies Vaccines -- Rabies vaccines for wildlife -- Human Rabies Vaccines -- Rabies vaccines, prophylactic, Peru -- Rabies Prevention in Asia: Institutionalizing Implementation Capacities -- Passive Immunity in Rabies Prophylaxis -- Rabies Little Virus Against Powerful Innate Immunity -- Novel Rabies Vaccines -- Assessing the potency of inactivated veterinary vaccines and oral live vaccines against rabies -- WHO Perspective on Rabies.
    Abstract: This book reviews the recent advances in rabies research and rabies vaccine development. The reader is introduced to biology and pathology of the virus, causing agents and the history of rabies vaccination. The book presents regional rabies prophylaxis programs and discusses vaccination strategies for wildlife and humans. Further, innate immune response as well as antibody response to rabies are examined. All chapters are written by renowned experts in rabies research, some of them part of the WHO Collaboration Centre for Rabies Surveillance and Research. The book targets researchers and health professionals working in Virology, Veterinary Medicine and Biomedicine. .
    Type of Medium: Online Resource
    Pages: VII, 205 p. 15 illus., 12 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030210847
    URL: https://doi.org/10.1007/978-3-030-21084-7
    DOI: 10.1007/978-3-030-21084-7
    DDC: 615
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  • 29
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    Online Resource
    Principles of Forensic Toxicology (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Forensic sciences. ; Medical jurisprudence. ; Pharmacology. ; Forensic Science. ; Forensic Medicine.
    Description / Table of Contents: Part 1: Introduction -- Post Mortem Forensic Toxicology -- Human Performance Toxicology -- Drug-Facilitated Sexual Assault -- Forensic Drug Testing -- Performance enhancing Drug Testing -- Drug Testing in Pain Management -- Pharmacokinetics and Pharmacodynamics -- Part II. Specimen Preparation -- Spectrophotometry -- Chromatography -- Derivatization -- Immunoassy -- Mass Spectrometry -- Quantitation -- Method Validation -- Measurement Uncertainty and Traceability -- Statistics in Forensic Toxicology -- Part III Analytes -- Alcohol -- Benzodiazapines -- Gammahydroxybutyric acid,- Miscellaneous Central Nervous System Depressants -- Opioids -- Cocanie -- Cannabis -- Amphetamines-Sympathomimetic Amines,- Hallucinogens and Psychedelics -- Antidepressants and Neuroleptics -- Miscellaneous Therapeutic Drugs -- Carbon Monoxide/Cyanide -- Inhalants -- Metals -- Part III Special Topics -- Stability of Drugs of Abuse in Biological Systems -- Postmortem Redistribution of Drugs -- Postmortem Clinical Testing -- Pharmacogenomics -- Hair Drug Testing -- Oral Fluid Testing -- Meconium Drug Testing -- Drugs in Embalmed Tissues.
    Abstract: The fifth edition of the best-selling Principles in Forensic Toxicology continues in the tradition of excellence in academic publishing. With over 10 years of classroom-tested and continually updated content, the new edition contains significant updates and 7 new chapters on new topics including drug-facilitated crimes, derivatization, quantitation, measurement uncertainty/traceability, statistics, oral fluid testing, and drugs in embalmed specimens. Part One covers the major sub-disciplines of forensic toxicology in addition to pharmacological concepts. Part Two addresses specimen preparation, laboratory testing and instrumental analysis, while Part Three discusses common analytes including cocaine, opioids, alcohol, and marijuana. Adopted for courses in many of the top universities for forensic science and used by respected medical examiner’s offices and crime laboratories worldwide, Principles of Forensic Toxicology prepares the next generation of forensic toxicologists and continues to be an important reference in professional practice.
    Type of Medium: Online Resource
    Pages: XIII, 691 p. 188 illus., 23 illus. in color. , online resource.
    Edition: 5th ed. 2020.
    ISBN: 9783030429171
    URL: https://doi.org/10.1007/978-3-030-42917-1
    DOI: 10.1007/978-3-030-42917-1
    DDC: 615
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  • 30
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    Online Resource
    Recent Advances in Therapeutic Drug Monitoring and Clinical Toxicology (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Toxicology. ; Pharmaceutical chemistry. ; Pharmacology. ; Toxicology. ; Pharmaceutics.
    Description / Table of Contents: Therapeutic and toxic concentration of drugs in biological matrices -- Analytical techniques for therapeutic drug monitoring and clinical toxicology -- Plasma therapeutic drug monitoring and clinical toxicology -- Dried blood spots in therapeutic drug monitoring and toxicology -- The role of artificial intelligence in therapeutic drug monitoring and clinical toxicity -- Therapeutic drug monitoring and optimal pharmacotherapy with medicines of narrow therapeutic index -- Therapeutic drug monitoring (TDM) and toxicological studies in alternative biological matrices -- Analyzing data from therapeutic drug monitoring, pharmacokinetics, and clinical toxicology studies -- Reducing toxicity in critically ill patients by using therapeutic drug monitoring -- Quality assurance of samples for therapeutic drug monitoring and clinical toxicology -- Therapeutic drug monitoring and toxicology of anticancer drugs -- Therapeutic drug monitoring and toxicology of immunosuppressant -- Therapeutic drug monitoring and toxicology: relevance of measuring metabolites -- Recent advances in nanosensors for Therapeutic Drug Monitoring (TDM) -- Organ toxicity by immunosuppressive drugs in solid organ transplantation -- Artificial intelligence-based techniques to assess drug toxicity in drug induced liver injury (DILI) disease -- Drug dose and therapy individualization -- Models for drug individualization: patient to population level -- Toxicity evaluation of nanomedicine -- Biochemical indices of drug toxicity -- Therapeutic drug monitoring and clinical toxicology: challenges and future directions.
    Abstract: This book gives an overview of therapeutic drug monitoring (TDM) and its clinical application. It also highlights recent advances in toxicological studies, as they relate to therapeutic drug monitoring. This is one of the few books available on the market that covers TDM. Therapeutic drug monitoring (TDM) is a clinical decision-making tool that enables dosage regimen adjustments based on clinical and laboratory measurements. TDM not only involves the measuring of drug concentrations but also interpretation of the results. There is a strong correlation between drug concentrations in body fluids and outcome than between dose and outcome. The chapters include coverage of analytical techniques, pharmacokinetics, therapeutic indices, artificial intelligence and recent advances in toxicological studies. The book fills a gap in published literature and provides reliable information on; Analytical techniques in TDM and clinical toxicology TDM and pharmacokinetic studies TDM of drugs with narrow therapeutic indices Artificial intelligence in TDM and clinical toxicology Future directions and challenges .
    Type of Medium: Online Resource
    Pages: XVIII, 381 p. 43 illus., 41 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031123986
    URL: https://doi.org/10.1007/978-3-031-12398-6
    DOI: 10.1007/978-3-031-12398-6
    DDC: 615
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  • 31
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    From PharmD to Industry : A Fellowship Guide (2023)
    Cham :Springer Nature Switzerland :
    Details
    Keywords: Pharmacology. ; Pharmacy. ; Career education. ; Pharmacology. ; Pharmacy. ; Career Skills.
    Description / Table of Contents: Fellowship 101 -- The First Professional Year (P1) -- The Second Professional Year (P2) -- The Third Professional Year (P3) -- The Fourth Professional Year (P4) -- Midyear Applications, Interviews, and Receptions -- Transitioning from Student to Fellow -- Navigating the Virtual Landscape.
    Abstract: For many Doctor of Pharmacy (PharmD) candidates, post-graduate training is a highly prestigious and sought after experience that can further one’s pre-existing education. Some of these post-graduate training opportunities include but are not limited to pharmacy residencies, pharmaceutical industry fellowships, and PhD/Masters programs. There is a large gap in the current Doctor of Pharmacy curriculum about pharmaceutical industry fellowship programs and potential pharmaceutical industry opportunities. Through the eyes of current industry fellows and professionals, this book serves as a resource to learn more about fellowship opportunities and their respective application processes. In addition, this manual aims to provide a clear and concise roadmap to achieving a career in industry through a fellowship program. Whether you are a current student pharmacist, post-graduate pharmacy trainee (pharmacy resident), or industry professional, this manual addresses the current landscape of industry fellowship programs, an overview of industry opportunities, and a glimpse into what being a fellow entails. Readers of this book can expect to gain: An overview of pharmaceutical industry fellowship programs and opportunities Helpful advice and insight from current fellows and industry professionals A streamlined pathway to navigating the fellowship application process An understanding of the journey from being a student, to achieving a fellowship, to becoming an industry professional This book bridges the gap in education surrounding pharmaceutical industry fellowships and pharmacy careers in industry and increases access to first-hand information and real-world perspectives of current professionals to provide a firm foundation for those interested in pursuing a career in industry or learning more about fellowship programs.
    Type of Medium: Online Resource
    Pages: XIX, 92 p. 4 illus., 3 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031357879
    Series Statement: SpringerBriefs in Pharmaceutical Science & Drug Development,
    URL: https://doi.org/10.1007/978-3-031-35787-9
    DOI: 10.1007/978-3-031-35787-9
    DDC: 615
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  • 32
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    Online Resource
    Contract Research and Development Organizations-Their History, Selection, and Utilization (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Pharmacy. ; Pharmacology. ; Pharmacy.
    Description / Table of Contents: Introduction -- History of CROs: Including CRO Snapshots and a CRO Genealogy Chart -- The Pharmaceutical Development Process & Testing Requirements -- The Medical Device Development Process & Testing Requirements -- Functions and Types of CROs -- Labs in China and India -- Selection of CROs -- Study Directors and PIs -- Nuts and Bolts of Study Performance SCG/CBS -- Electronic Reporting Requirements (SEND & eCTD) -- Study and Project Monitoring -- Contracting, Pricing, and Cost of Works Performed by CROs -- Consultants and their Role -- Building Relationships: Maximizing your return on Expectations with a CRO -- Common Problems and their Solutions -- Appendices: A Toxicology Labs B Medical Device Labs C Phase I Labs D Analytical Labs E GMP Contract Facilities F Formulation G Dosage Forms H Clinical Testing I Regulatory Services J Forms and Checklists -- K Specialized Services -- L Consultants Known to be In-Practice -- Index. .
    Abstract: This volume provides a complete update of all the materials in prior volumes on the subject (including current directories to testing labs and other support establishments worldwide), while adding substantial new material on the following topics: · The history of CROs, including snapshots of CROs and a genealogy chart making clear where they came from and where they went. · Study directors and principal investigators. · The nuts and bolts of study performance. · Electronic reporting requirements – SEND and eCTD (required for NDA, BLA, ANDA, and IND submissions). · Consultants and their roles. · An expanded examination of common problems and their solutions. This book boasts complete directories to the global universe of operating labs – where they are, how to contact them, and what they do (including special capabilities). Additionally, checklists for qualifying labs and manufacturing facilities – and for auditing studies and projects at such facilities – are included. It is directed at those in industry (specifically directed at those working for companies using CRO services) but will also be of interest to scientists or administrators working in research organizations themselves. In this case, the contents of this new work are essential to the target reader because the work, regulations, and actors (CROs) have evolved and changed at a rapid pace in the 10 years since the earlier volume that the author published. Likewise, the companies using these services have come to all be almost completely dependent on outsourcing. The earlier texts remain the only source of their kind (paper or electronic) on the field and the only noncommercial guide to the global industry and this volume provides a complete update.
    Type of Medium: Online Resource
    Pages: XIII, 519 p. 19 illus., 1 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030430733
    URL: https://doi.org/10.1007/978-3-030-43073-3
    DOI: 10.1007/978-3-030-43073-3
    DDC: 615
    Language: English
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    Toll-like Receptors in Health and Disease (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Immunology. ; Inflammation. ; Pharmacology. ; Immunology. ; Inflammation.
    Description / Table of Contents: Intracellular TLRs (TLR3, TLR7, and TRL9) in host defense or TLRs in mast cells -- Toll-like receptors as drug targets in the intestinal epithelium -- Innate immune memory-priming, tolerance and exhaustion-in health and disease -- TLRs in brain immunity -- TLRs in cerebrovascular diseases -- TLRs in stem cells or progenitor cells -- TLRs in adaptive immunity -- Overview on TLRs in immunity -- TLR10 and its role in immunity.
    Abstract: The current book is focussed on the Toll-like receptors (TLRs), which are the first pattern recognition receptors (PRRs) discovered in humans. For example, TLR4 was first recognized in humans in 1997 as a PRR recognizing the Gram-negative bacterial lipopolysaccharide (LPS). This discovery revolutionized the field of innate immunity and filled the long-standing gap in the pathogen recognition by the immune system. Now, it is well established that humans have 10 (TLR1-TLR10) and mice have 12 (TLR1-TLR13) functional TLRs, excluding TLR10 that is present as a defective pseudogene. TLRs are present as both membrane-bound extracellular (TLR1, TLR2, TLR4, TLR5, TLR6, and TLR10) and intracellular (TLR3, TLR7, TLR8, and TLR9) PRRs in humans, which identify different pathogen or microbe-associated molecular patterns (PAMPs or MAMPs) and death or damage-associated molecular patterns (DAMPs) released by the host cells. A lot of development in the TLR biology has occurred in last 24 years since there first discovery in humans. The book is intended to describe their role in the host defence, human reproduction, non-infectious sterile inflammatory conditions, including brain immunity and cerebrovascular diseases, signaling mechanisms, adaptive immunity, and their targeting for drug development.
    Type of Medium: Online Resource
    Pages: VIII, 314 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031065125
    Series Statement: Handbook of Experimental Pharmacology, 276
    URL: https://doi.org/10.1007/978-3-031-06512-5
    DOI: 10.1007/978-3-031-06512-5
    DDC: 615
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    Prebiotics, Probiotics and Nutraceuticals (2022)
    Singapore :Springer Nature Singapore :
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    Keywords: Pharmacology. ; Clinical medicine Research. ; Medicine Research. ; Biology Research. ; Pharmacology. ; Clinical Research. ; Biomedical Research.
    Description / Table of Contents: Chapter 1. Potentiality of Probiotics in Inactivation of Tetrodotoxin -- Chapter 2. Therapeutic Strategy for the Deterrence of COVID-19 with Relevance to Probiotics -- Chapter 3. Plant based Bioactive compounds in Cancer Therapeutics -- Chapter 4. Therapeutic Strategy for the Deterrence of COVID-19 with Relevance to Probiotics -- Chapter 5. Probiotics as efficacious therapeutic option for treating gut-related diseases: molecular and immunobiological perspectives -- Chapter 6. The progressive development of probiotics, prebiotics, synbiotics research, and its multipurpose use in the ornamental fishery -- Chapter 7. The commercial perspective of probiotics, and bioremediating components in aquaculture pond management: A Case Study -- Chapter 8. Prebiotics as promising therapeutics for treating gut-related disorders : Biochemical and Molecular Perspectives -- Chapter 9. Prebiotics and Probiotics as Functional Foods: Prospect and Promises in Metabolic Diseases. Chapter 10. Implications of probiotics and prebiotics on immune functions -- Chapter 11. Recent Trends in Natural Medicines and Nutraceuticals Research -- Chapter 12. Nutraceuticals-are alternative to modern medicines- Chapter 13. Socio-Economic Study of Prospective of probiotic, prebiotic and synbiotic for sustainable development of aquaculture in Indian Sunderban -- Chapter 14. Drosophila melanogaster as an in-vivo model for the investigation of host microbiota interaction -- Chapter 15. Prospectives of Prebiotics, Probiotics and Synbiotics for Sustainable Development of Aquaculture.
    Abstract: The book titled ‘Prebiotics, Probiotics and Nutraceuticals’ is expected to direct many emerging research pathwaysneed at local and global levels for nutrition and food supplements for developing immunity for healthy life. This volume incorporates sixteen seminal papers on issue based research and their practical applications covering latest information and progress on different area of nutritional supplement research fight against disease. The book highlights the frontier issues and applications in nutritional biotechnology with wide coverage of the themes like Potentiality of Probiotics in Inactivation of Tetrodotoxin, Therapeutic Strategy for the Deterrence of COVID-19 with Relevance to Probiotics and Prospectives of Prebiotics, Probiotics and Synbiotics for Sustainable Development in Aquaculture.Plant based Bioactive compounds in Cancer Therapeutics, Recent Trends in Natural Medicines and Nutraceuticals Research, Probiotics as efficacious therapeutic option for treating gut-related diseases: molecular and immune-biological perspectives, The progressive development of probiotics, prebiotics, synbiotics research, and its multipurpose use in the ornamental fishery, The commercial perspective of probiotics, and bioremediating components in aquaculture pond management: A Case Study andPrebiotics as promising therapeutics for treating gut-related disorders : Biochemical and Molecular Perspectives. Prebiotics and Probiotics as Functional Foods: Prospect and Promises in Metabolic Diseases, Implications of probiotics and prebiotics on immune functions. Recent Trends in Natural Medicines and Nutraceuticals Research, Nutraceuticals are alternative to modern medicines, Socio-Economic Study of Prospective of probiotic, prebiotic and synbiotic for sustainable development of aquaculture in Indian Sunderban. This book will be very useful for the scholars, biotechnologists, agricultural scientists, nutritionist, medical doctors, researchers, teachers and students in the emerging field of biotechnology.
    Type of Medium: Online Resource
    Pages: XVI, 340 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811689901
    URL: https://doi.org/10.1007/978-981-16-8990-1
    DOI: 10.1007/978-981-16-8990-1
    DDC: 615
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    Botulinum Toxin Treatment in Surgery, Dentistry, and Veterinary Medicine (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Surgery. ; Dentistry. ; Veterinary medicine. ; Neurology . ; Orthopedic surgery. ; Pharmacology. ; Surgery. ; Dentistry. ; Veterinary Science. ; Neurology. ; Surgical Orthopedics.
    Description / Table of Contents: 1. History of development of botulinum toxin therapy in medical and surgical fields -- 2. Molecular structure and mechanisms of action of botulinum toxins as it pertains to clinical symptoms -- 3. Types of toxins in commercial use, their similarities and differences -- 4. A review of current Botulinum toxin treatment indications in medical field. - 5. Mechanisms of Analgesic effects of botulinum neurotoxins -- 6. Botulinum toxin treatment in Head and neck surgery -- 7. Botulinum toxin treatment of thoracic and abdominal surgery -- 8. Botulinum Toxin A in Abdominal Wall Reconstruction -- 9. Use of Botulinum toxin A in post-mastectomy breast reconstruction -- 10. Botulinum Toxins for Treatment of Pain in Orthopedic Disorders -- 11. Botulinum toxin for pediatric patients, Who? For what? When? -- 12. Botulinum Toxin Treatment in Plastic Surgery -- 13. Botulinum Toxin Treatment in Ophthalmology and Ophthalmic surgery -- 14. Botulinum Toxin Treatment in Gastrointestinal Disorders -- 15. Botulinum Toxin Treatment in Urological Disorders -- 16. Botulinum Toxin Treatment in Dentistry -- 17. Botulinum toxin treatment in Veterinary Medicine - Clinical implications -- 18. Future Perspectives of Botulinum Toxin Application In Dentistry.
    Abstract: All books on the market which have been written on the subject of botulinum toxin therapy focus on treatment of hyperactive movement disorders, autonomic dysfunction (bladder, sweat and salivary glands) and some pain indications (migraine). Reference to pre-or post -surgical indications are brief and often out-dated. No book has information on dentistry or veterinary medicine. This book provides up-to-date information on botulinum toxin therapy in surgical fields. It is also the only book in the market that provides information on botulinum toxin therapy in dentistry and veterinary medicine and furnishes the latest information. Botulinum Toxin Treatment in Surgery, Dentistry, and Veterinary Medicine appeals to many disciplines including surgery, dentistry and veterinary medicines well as appealing to neurologists and internists.
    Type of Medium: Online Resource
    Pages: VIII, 398 p. 70 illus., 60 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030506919
    URL: https://doi.org/10.1007/978-3-030-50691-9
    DOI: 10.1007/978-3-030-50691-9
    DDC: 615
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    Metabolomics and Its Impact on Health and Diseases (2023)
    Cham :Springer International Publishing :
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    Keywords: Pharmacology. ; Biochemical markers. ; Cytology. ; Analytical biochemistry. ; Pharmacology. ; Biomarkers. ; Cell Biology. ; Analytical Biochemistry.
    Description / Table of Contents: Preface -- Practical Aspects of NMR-Based Metabolomics -- Compound Identification in Mass Spectrometry-Based Metabolomics -- METABOLOMICS USING NMR – Avoiding the ‘Black-Box’ -- Natural products drug discovery: on silica or in silico?- Quantitative NMR Methods in Metabolomics -- Advancements in pulsed stable isotope resolved metabolomics -- Metabolomics in Cell Biology -- NMR-based metabolomics to evaluate individual response to treatments -- Pharmacometabolomics of Asthma as a road map to Precision Medicine -- Prospective metabolomic studies in precision medicine -- Chemotherapy-induced Peripheral Neuropathy -- Metabolomics of Respiratory Diseases.
    Abstract: This volume of the Handbook of Experimental Pharmacology, which celebrated its 100th anniversary in 2019, addresses the rapidly growing and evolving field of metabolomics. It has been compiled and designed to broaden and enrich your understanding as well as simplify a complicated picture of the diverse field of metabolomics. This is accomplished by chapters from experts in the field on basic principles as well as reviews and updates of analytical techniques. The variety and different perspectives of the NMR approaches are described in the chapters By David Wishart, Daniel Raftery and Ryan McKay, while mass spectrometry advances are covered by Charles R. Evans and Stefan Kempa. This book also reflects the state of the art in the application of metabolomics to cell biology (Marta Cascante and Ulrich Guenther) and chapters that share insights into the application of metabolomics in various diseases (Paola Turano and Claudio Luchinat, Rachel S. Kelly and Jessica Lasky-Su, Paige Lacy, and Angela Rogers. Relationships of metabolomics with drugs are highlighted by Robert Verpoorte (natural products drug discovery), by Oscar Millet and by Turano and Luchinat (perspectives in precision medicine) and by Daniel L. Hertz (drug-induced peripheral neuropathy). From the above list of diverse topics, we believe this book has interdisciplinary appeal and scholars with an interest in the role of metabolomics in achieving precision medicine will find it of particular or special interest.
    Type of Medium: Online Resource
    Pages: VIII, 384 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031268595
    Series Statement: Handbook of Experimental Pharmacology, 277
    URL: https://doi.org/10.1007/978-3-031-26859-5
    DOI: 10.1007/978-3-031-26859-5
    DDC: 615
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    Structure and Health Effects of Natural Products on Diabetes Mellitus (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Botanical chemistry. ; Bioorganic chemistry. ; Pharmacology. ; Plant Biochemistry. ; Bioorganic Chemistry.
    Description / Table of Contents: Chapter 1. Introduction of diabetes melitus and future prospects of natural products on diabetes melitus -- Chapter 2. Anoverview of hypoglycemic modern drugs -- Chapter 3. An overview of hypoglycemic biological drugs -- Chapter 4. An overview of hypoglycemic traditionaldrugs -- Chapter 5. Glycosides from natural sources in the treatment of diabetes mellitus -- Chapter 6. Isolation and Structure Elucidation of Hypoglycemic Compounds -- Chapter 7. Structural Characterization and Health Effects of Polysaccharides from Momordica charantia on Diabetes Mellitus -- Chapter 8. Effects of polysaccharides on reducing blood glucose based on gut microbiota alteration -- Chapter 9. An Overview of Polysaccharides and the influencefactors of Hypoglycemic Activity -- Chapter 10. Plant Secondary Metabolites with α-Glucosidase Inhibitory Activity. - Chapter 11. Rhinacanthin-C and Its Potential to Control Diabetes Mellitus -- Chapter 12. Regeneration of beta cells by inhibition of pro-apoptotic proteins through phytocompound in STZ induced diabetic albino wistar rats-invivo and insilico approach. - Chapter 13. Nitrogenous Compounds from Plant Origin in Management of -- Chapter 14. Plant Alkaloids with Antidiabetic Potential -- Chapter 15. The role of Alkaloids in the Management of Diabetes Mellitus -- Chapter 16. Traditional Indian Herbs for the Management of Diabetes Mellitus and their Herb-Drug Interaction Potentials: An Evidence-Based Review -- Chapter 17. Role of Micronutrients and Trace elements in Diabetes mellitus: A Review.
    Abstract: The purpose of this book is to introduce the classified chemical components of hypoglycemic compounds in natural products, summarize the recent research progress of natural products with hypoglycemic activity in the past 20 years, and provide the original analysis and development opinions of relevant scholars. Hypoglycemic compounds are to target diabetes mellitus, an important public health problem, one of four priority noncommunicable diseases (NCDs) targeted for action by world leaders. Diabetes mellitus is a common endocrine and metabolic disease, which not only causes physiological damage to patients' kidneys, cardiovascular and cerebrovascular vessels, peripheral blood vessels, nerves and eyes, but also causes mental and psychological pressure to patients. Due to the evidence that traditional medicine and natural herbal formula have advantages in treating diabetes, natural products with hypoglycemic activity have been studied extensively in recent years and have been accepted by many scholars all over the world. This book focuses on the progress on the study of the structure, hypoglycemic activities, structure-activity relationships and mechanism of a wide range of polysaccharides, flavonoids, saponins, alkaloids, terpenoids, polyphenols and other constituents. It will help students and researchers to understand current approaches and progress in the treatment of diabetes with natural products, which may also be beneficial to develop new hypoglycemic drugs.
    Type of Medium: Online Resource
    Pages: VIII, 307 p. 85 illus., 16 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811587917
    URL: https://doi.org/10.1007/978-981-15-8791-7
    DOI: 10.1007/978-981-15-8791-7
    DDC: 615
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    Pharmacology of Immunosuppression (2022)
    Cham :Springer International Publishing :
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    Keywords: Pharmacology. ; Human physiology. ; Immunology. ; Surgery. ; Pharmacology. ; Human Physiology. ; Immunology. ; Surgery.
    Description / Table of Contents: Review of the Pathophysiology of the Alloimmune response -- A Comprehensive Review of Calcineurin Inhibitors Used for Immunosuppression in Cardiac Transplantation -- Anti-proliferative Agents -- Mechanistic Target of Rapamycin (mTOR) Inhibitors -- Corticosteroids -- Induction therapy and antibodies -- Immunosuppression and Heart Transplantation -- Immunosuppression and Lung Transplantation -- Immunosuppression and renal transplant recipients -- Immunosuppression in Rheumatologic and Auto-immune Disease -- Immunosuppression in Bone Marrow Transplantation -- Immunosuppression in Multiple Sclerosis and Other Neurologic Disorders -- Novel immunosuppressive agents for the treatment of organ transplants -- Adverse Effects of Immunosuppression: Infections -- Malignancy: An Adverse Effect of Immunosuppression -- Adverse Effects of Immunosuppression:Nephrotoxicity, Hypertension and Metabolic Disease.
    Abstract: The goal of this book is to provide a guide and detailed review of immunosuppression in terms of molecular mechanisms of action, side effects and clinical trials that validated their utility. This includes their use in solid organ transplantation, bone marrow transplantation and autoimmune diseases and inflammatory diseases. This book is a critical review of these topics and a vital resource.
    Type of Medium: Online Resource
    Pages: VIII, 348 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031051180
    Series Statement: Handbook of Experimental Pharmacology, 272
    URL: https://doi.org/10.1007/978-3-031-05118-0
    DOI: 10.1007/978-3-031-05118-0
    DDC: 615
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    Evidence Based Validation of Traditional Medicines : A comprehensive Approach (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Medical microbiology. ; Medicinal chemistry. ; Pharmacovigilance. ; Pharmacology. ; Medical Microbiology. ; Medicinal Chemistry. ; Drug Safety and Pharmacovigilance.
    Description / Table of Contents: Chapter 1. Global Approach for Drug Discovery and Development from Indian Traditional Medicine -- Chapter 2. Bioactive Natural Leads TargetingCancer Cell Metabolism -- Chapter 3. Omics Technologies and Development of Anti-diabetic Therapies from Prospective Natural Products -- Chapter 4. Amaryllidaceae Alkaloids as Anti-inflammatory Agents Targeting Cholinergic Anti-inflammatory Pathway: Mechanisms and Prospects -- Chapter 5. Neurodegenerative Diseases and Small Molecule Protein Chaperone Activator of Natural Origin -- Chapter 6. Role of Phytomolecules on the Basic Biology of Aging -- Chapter 7. Role of phytomedicine in alleviating oxidative stress mediated vascular complications in diabetes -- Chapter 8. Plant Based -Secretase (BACE-1) Inhibitors: A Mechanistic Approach to Encounter Alzheimer's Disorder -- Chapter 9. Bioactive Compounds of Mangroves as Potent Drug and in Nanoparticle Synthesis - Play a Pivotal Role in Combating Human Pathogens. Chapter 10. Medicinal Plants: A Rich Source of Bioactive Molecules Used in Drug Development -- Chapter 11. Cell-based Assays in Natural Product-based Drug Discovery -- Chapter 12. Allelochemicals: An Emerging Tool for Weed Management -- Chapter 13. Secondary Metabolites of Higher Plants as Green Preservatives of Herbal Raw Materials and Their Active Principles During Postharvest Processing -- Chapter 14. Importance of Chromatography Techniques in Phytomedicine Research -- Chapter 15. Reverse Pharmacology – A Tool for Drug Discovery From Traditional Medicine -- Chapter 16. Role of Modern Biological Techniques in Evidence-Based Validation of Ayurvedic Herbometallic Preparations -- Chapter 17. HPTLC Fingerprinting analysis of Phytoconstituents from Indigenous Medicinal Plants -- Chapter 18. Climate Change,Geographical Location and Other Allied Triggering Factors Modulate the Standardization and Characterization of Traditional Medicinal Plants: AChallenges and Prospect for Phyto-Drug Development -- Chapter 19. Molecular Docking Studies of Plant-Derived Bioactive Compounds: A Comprehensive in silico Standardization Approach -- Chapter 20. Standardization and Quality Evaluation of Botanicals with Special Reference to Marker Components -- Chapter 21. Analytical Standardization of Haridra Formulation by UV-VIS Spectrophotometry and RP-HPLC -- Chapter 22. Ethnobotanical survey: the foundation to evidence based validation of medicinal plants -- Chapter 23. Phytotherapeutics: The Rising Role of Drug Transporters in Herb-Drug Interactions with Botanical Supplements -- Chapter 24. An Insight into Herb Interactions: Clinical Evidence Based Overview -- Chapter 25. Pharmacovigilance of Herbal Medicines: An Overview -- Chapter 26. Herbal Drugs: Efficacy, Toxicity and Safety Issues -- Chapter 27. Herbal Drug Patenting -- Chapter 28. Safety and Regulatory Issues on Traditional Medicine Entrusted Drug Discovery -- Chapter 29. Pharmacovigilance of Herbal Medicine: An Evolving Discipline -- Chapter 30. Toxicity Studies Related to Medicinal Plants -- Chapter 31. Herb-Drug Interactions -- Chapter 32. Plant Based Traditional Herbal Contraceptive Use in India: Safety and Regulatory Issues -- Chapter 33. Traditional Medicine Stability and Pharmacokinetic Issue -- Chapter 34. Pharmacovigilance: Methods in developing the safety and acceptability of traditional medicines -- Chapter 35. Zoopharmacognosy (Plant-Animal Interaction) -- Chapter 36. Significance of Stability and Pharmacokinetic issues in Traditional Medicine -- Chapter 37. Pharmaceutical Formulations Development Based on the Polymers Obtained from Edible Plants: An Excellent Approach for the Betterment in Health Care Services -- Chapter 38. Evaluation of bioactivity of green nanoparticles synthesized from traditionally used medicinal plants: a review -- Chapter 39. Physicochemical, Micromeritics, Biomedical and Pharmaceutical Applications of Assam Bora Rice Starch -- Chapter 40. Natural Excipients in Pharmaceutical Formulations -- Chapter 41. A Wonder Plant Withania: Pharmacological and Chemical Perspectives -- Chapter 42. Immunomodulators and Phyto Drugs -- Chapter 43. Combined Effects of Plant Extracts on Ovarian Cell Functioning -- Chapter 44. Pterocarpussantalinus: A Wonder Gift of Nature -- Chapter 45. Phytochemicals And Investigations On Traditionally Used Medicinal Mushrooms -- Chapter 46. A Review On Investigational Studies Of Marine Macroalgae Spogomorpha Indica L -- Chapter 47. Validation of Traditional Claim of Oxalis debilis Kunth., An Ethnomedicinal Plant from North-eastern Region of India -- Chapter 48. Traditional Herbal Medicine Practiced in Plateau-Fringe and Rarh Districts of West Bengal, India -- Chapter 49. Pharmacology and Mechanisms of Natural Medicine in Treatment of Type 2 Diabetes Mellitus -- Chapter 50. Indian Traditional Herbs and Alzheimer’s Disease: Integrating Ethnobotany and Phytotherapy. .
    Abstract: The demand for traditional medicines, herbal health products, herbal pharmaceuticals, nutraceuticals, food supplements and herbal cosmetics etc. is increasing globally due to the growing recognition of these products as mainly non-toxic, having lesser side effects, better compatibility with physiological flora, and availability at affordable prices. In the last century, medical science has made incredible advances all over the globe. In spite of global reorganization and a very sound history of traditional uses, the promotion of traditional medicine faces a number of challenges around the globe, primarily in developed nations. Regulation and safety is the high concern for the promotion of traditional medicine. Quality issues and quality control, pharmacogivilane, scientific investigation and validation, intellectual property rights, and biopiracy are some key issues that restrain the advancement of traditional medicine around the globe. This book contains diverse and unique chapters, explaining in detail various subsections like phytomolecule, drug discovery and modern techniques, standardization and validation of traditional medicine, and medicinal plants, safety and regulatory issue of traditional medicine, pharmaceutical excipients from nature, plants for future. The contents of the book will be useful for the academicians, researchers and people working in the area of traditional medicine. .
    Type of Medium: Online Resource
    Pages: XII, 1151 p. 378 illus., 125 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811581274
    URL: https://doi.org/10.1007/978-981-15-8127-4
    DOI: 10.1007/978-981-15-8127-4
    DDC: 615
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    From Obesity to Diabetes (2022)
    Cham :Springer International Publishing :
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    Keywords: Pharmacology. ; Metabolism Disorders. ; Pharmacology. ; Metabolic Disease.
    Description / Table of Contents: Part I Obesity. Epidemiology of Obesity -- The Circadian Clock and Obesity -- Nutrition and Microbiome -- From Obesity to Diabetes: The Role of the Adipose Organ -- Targeting Epicardial Fat in Obesity and Diabetes Pharmacotherapy -- The Enteroendocrine System in Obesity -- Insights from Studies of White Adipose Tissue Using Single-Cell Approaches -- Obesity-Related Insulin Resistance: The Central Role of Adipose Tissue Dysfunction -- Obesity, Senescence, and Senolytics -- Obesity and Obstructive Sleep Apnea -- Part II Diabetes and Complications. Inter-Organ Crosstalk in the Development of Obesity-Associated Insulin Resistance -- Islet Inflammation and β Cell Dysfunction in Type 2 Diabetes -- NAFLD and NASH: The Metabolically Diseased Liver -- Diabetic Kidney Disease: From Pathogenesis to Novel Treatment Possibilities -- Diabetic Peripheral Neuropathy -- Part III Lifestyle Modifications and Future Treatments. Weight Loss Strategies -- Physical Activity, Obesity and Weight Loss Maintenance -- Bariatric/Metabolic Surgery -- Drugs for Treating Obesity -- Novel Drugs for Diabetes Therapy -- Novel Approaches to Restore Pancreatic Beta-Cell Mass and Function -- Precision Medicine and Obesity -- Targeting the Enteroendocrine System for Treatment of Obesity.
    Abstract: Obesity is a major risk factor for the development of type 2 diabetes and its associated complications, a major socio-economic burden for health care systems. The worldwide prevalence of obesity doubled since 1980 and as a consequence the number of patients with diabetes has been continuously rising with more than 450 Mio. people suffering from this disease at the present time. Substantial progress has been made in understanding the molecular pathways leading from excessive fat accumulation to metabolic perturbation and finally diabetes manifestation. This edition of the "Handbook of Experimental Pharmacology" aims to analyze new insight into the pathophysiology of obesity, to decipher the complex links to diabetes and its complications, and to collect most recent information on new strategies for prevention and treatment of obesity and diabetes.
    Type of Medium: Online Resource
    Pages: VIII, 513 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030999957
    Series Statement: Handbook of Experimental Pharmacology, 274
    URL: https://doi.org/10.1007/978-3-030-99995-7
    DOI: 10.1007/978-3-030-99995-7
    DDC: 615
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    Immunity Boosting Medicinal Plants of the Western Himalayas (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Natural products. ; Botany. ; Ethnology. ; Pharmacology. ; Natural Products. ; Plant Science. ; Ethnography.
    Description / Table of Contents: 1. Introduction to Western Himalayas -- 2. Achillea millefolium L., Common Yarrow -- 3. Arisaema jacquemontii Blume, Jacquemont's Cobra Lily -- 4. Species of Arnebia genus found in the western Himalayas -- 5. Species of the Berberis genus found in the western Himalayas -- 6. Dactylorhiza hatagirea (D.Don) Soo – Himalayan Marsh Orchid -- 7. Fritillaria roylei Hook.f.: Himalayan Fritillary -- 8. Gentiana kurroo Royle: Himalayan Gentian -- 9. Habenaria intermedia D.Don and Habenaria edgeworthii Hook., f. ex Collett.: The Western Himalayan medicinal Plants -- 10. Humulus lupulus L.: Beer plant -- 11. Inula racemosa Hook. f. – Puskarmool: Its ethnobotanical uses, phytochemicals and pharmacological activities -- 12. Juniperus recurva Buch.-Ham. ex D.Don and Juniperus squamata D. Don: Himalayan Juniper -- 13. Lancea tibetica Hook.f. & Thomson: Ethnobotany, phytochemistry and pharmacology -- 14. Malaxis muscifera (Lindley) O. Kuntze. and Malaxis acuminata D. Don.: Jeevak -- 15. Picrorhiza kurroa Royle ex Benth.: Kutki -- 16. Species of the genus Polygonatum found in the Western Himalayas -- 17. Species of the genus Rhodiola found in the Western Himalayas -- 18. Saussurea lappa C.B. Clarke: Kushta/Kut -- 19. Saussurea lappa C.B. Clarke: Kushta/Kut -- 20. Species of the genus Selinum found in the western Himalayas -- 21. Swertia chirayita (Roxb. ex Flem.): Chirayata/Chiretta -- 22. Taxus wallichiana Zucc.: The Himalayan yew -- 23. Tribulus terrestris L.: Gokshur /Gokharu -- 24. Species the Genus Viola found in Western Himalayas.
    Abstract: This book presents a comprehensive guide to traditional immunity-boosting medicinal plants of the Himalayas, their traditional uses, phytochemistry, pharmacology, diversity, conversation, biotechnology, toxicology, as well as future prospective. All the chapters cover the latest advances in ethnobotany, phytochemistry, biochemistry, and biotechnology. The book offers a valuable asset for researchers and graduate students of chemistry, botany, biotechnology, microbiology, and the pharmaceutical sciences. The main purpose of the present book is to draw on the rich culture, folklore, and biodiversity of immunity-boosting medicinal plants of the Western Himalayas, with particular emphasis on the Indian Trans-Himalayan and Western Himalayan region. All the plants included in the present book are extensively used by the local tribes and people for their health-promoting properties from ancient times. This book will be a substantial contribution to the knowledge of the region and the country. Also, the book will be very useful to scientists, graduates, and undergraduates, along with researchers in the fields of natural products, herbal medicines, ethnobotany, pharmacology, chemistry, and biology. Further, it is an equally significant resource for a person working in different traditional medicinal systems; doctors (especially those engaged in Ayurveda, Chinese traditional medicinal system, Amchi, and allopathy); the pharmaceutical industry (for drug design and synthesis); biochemistry and biotechnology sciences; and the agricultural sciences. .
    Type of Medium: Online Resource
    Pages: XIX, 609 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811995019
    URL: https://doi.org/10.1007/978-981-19-9501-9
    DOI: 10.1007/978-981-19-9501-9
    DDC: 615
    Language: English
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    Online Resource
    Nanoformulations in Human Health : Challenges and Approaches (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Therapeutics. ; Pharmacology. ; Therapeutics.
    Description / Table of Contents: Nano-technological Platforms and Manipulations for the Emerging Ocular Manifestations -- Phytonanomedicines as Topical Alternatives for the Treatment of Skin Cancer -- Nano-sized Labile and Particulate Ingredients in Topical Formulations: A Strategic Approach Against Photoageing and Photocarcinogenisis -- Application of Biocompatible Nanocarriers in Glaucoma: Challenges and Advances -- Nano-carriers for Natural Therapeutics in the Management of Neuropathic Pain -- Advances in the Delivery of Therapeutic Peptides -- Nanoformulations and Their Role in Colon Targeting -- Theranostic Nanoformulations: Merging Diagnostics and Therapeutics -- The Role of Nanoformulations in Nose-To-Brain Drug Delivery -- Cubic Lyotropic Liquid Crystalline Nanostructures: A Versatile Platform for Delivery -- Preformulation Challenges: The Concept Behind the Selection, Design, and Preparation of Nanoformulations -- Nanoethosomes for Topical Fungal Therapeutics -- Comparison of Therapeutic Efficiency of Nanoformulations of Curcumin vs. Tetrahydrocurcumin in Various Disorders -- Nanomedicinal Approaches of Phytotherapeutics to Treat Alzheimers Disease -- Nanoparticulate Approaches to Exploit the Pathophysiology of Rheumatoid and Osteoarthritis -- Emerging Nanotechnology in Chronic Respiratory Diseases -- Conventional and Non-conventional Approaches of Site-specific Targeting of Therapeutics in Some Infectious Diseases and Metabolic Disorders -- Nanoformulations in Human Health Conditions: The Paradigm Shift -- Magnetic Nanoparticles Nanoformulation for Alternative Therapy of Cancer by Super-paramagnetic Hyperthermia -- Nano-weapons Against Tuberculosis -- Drug-Excipient Interactions in Nanoformulations with Special Focus on Impurity Control per ICH guidelines.
    Abstract: This book is an amalgamation of knowledge, experience, and expertise in various aspects of nanotechnology, by experts who are proficient in designing novel nanoformulations that are used in the treatment of various challenging and prevalent diseases. It is an exhaustive compilation of the multi-faceted arena of nanoformulations and the healthcare system that caters to the needs of academicians, scholars, researchers, etc. The most important aspect of the book covers various types of nanoformulations and their applications in the treatment of communicable and non-communicable diseases. Each chapter focuses on a particular nanoformulation as well as a disease including the pathophysiology of the disease, the current treatment modalities of diseases, the role of nanoformulation in treatment and other future aspects and directions for further work. Coverage includes neuropathic pain, colon targeting, nose-to-brain drug delivery, cancer, arthritis and tuberculosis.
    Type of Medium: Online Resource
    Pages: XVIII, 548 p. 106 illus., 91 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030418588
    URL: https://doi.org/10.1007/978-3-030-41858-8
    DOI: 10.1007/978-3-030-41858-8
    DDC: 615
    Language: English
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    Online Resource
    Emerging Technologies for Nanoparticle Manufacturing (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Nanotechnology. ; Nanochemistry. ; Pharmacology. ; Nanotechnology. ; Nanochemistry.
    Description / Table of Contents: Part 1 Introduction and Biomedical Applications of Nanoparticles -- 1. Introduction to Nanomaterials and Nanotechnology -- 2. Biomedical Applications of Nanoparticles -- Part II-Polymeric Nanoparticles -- 3. Nanocrystallization and Nanoprecipitation Technologies -- 4. Microfluidics Technology for Nanoparticles and Equipment-. 5. Production of Nanocomposites via Extrusion Techniques -- 6. The Use of Supercritical Fluids Technologies for Nanoparticle Production -- 7. Salting out and Ionic Gelation Manufacturing Techniques for Nanoparticles -- 8. Nanogel Synthesis by Irradiation of Aqueous Polymer Solutions -- 9. Cellulose acetate based nanofibers: Synthesis, Manufacturing and Applications -- 10. Production of nanofibers, environmental challenges and solutions -- Part III-Lipid Nanoparticles -- 11. High Pressure Homogenization Techniques for Nanoparticles -- 12. Solvent emulsification evaporation and solvent emulsification diffusion techniques for nanoparticles -- 13. Ultrasound Activated Nanoemulsions -- 14. Multiple Emulsions: Emphasizing on industrial applications -- 15. Membrane techniques for the preparation of nanomaterials -- 16. Self-assembling Lipid Nanoparticles/Nanosystems (SLNN) using Hydrophilic Solvents: Overview and Industrial Uses -- 17. Nanoemulsions – An emerging technology in drug delivery -- Part IV- Metallic Nanoparticles -- 18. Manufacturing techniques for carbon nanotubes, gold nanoparticles and silver nanoparticles -- 19. Radio frequency (RF) plasma-based Synthesis of metallic Nano particles for Biomedical Application -- 20. Techniques for accurate sizing of nanoparticles -- 21. Silver nanoparticles synthesis from cyanobacteria: Environmental and biomedical applications -- 22. Selenium Nanoparticles: Green Synthesis and Exploitation -- Part V- Quality control for nanoparticles -- 23. Practical guidelines for the characterization and quality control of nanoparticlesin the pharmaceutical industry -- Part VI-Challenges in scale-up production of nanoparticles -- 24. Nanomedicine Scale-Up Technologies: Feasibilities and Challenges -- 25. Patent survey on recent technology for nanoparticles -- Part VII-Injectable Nanosystems -- 26. Injectable Nanosystems and Inherent Nano-Serum Interactions -- Part VIII- Future directions and challenges -- 27. Current Challenges and Future Directions in Nanomedicine.
    Abstract: This book provides an overview of nanoparticle production methods, scale-up issues drawing attention to industrial applicability, and addresses their successful applications for commercial use. There is a need for a reference book which will address various aspects of recent progress in the methods of development of nanoparticles with a focus on polymeric and lipid nanoparticles, their scale-up techniques, and challenges in their commercialization. There is no consolidated reference book that discusses the emerging technologies for nanoparticle manufacturing. This book focuses on the following major aspects of emerging technologies for nano particle manufacturing. I. Introduction and Biomedical Applications of Nanoparticles II. Polymeric Nanoparticles III. Lipid Nanoparticles IV. Metallic Nanoparticles V. Quality Control for Nanoparticles VI. Challenges in Scale-Up Production of Nanoparticles VII. Injectable Nanosystems VIII. Future Directions and Challenges Leading scientists are selected as chapter authors who have contributed significantly in this field and they focus more on emerging technologies for nanoparticle manufacturing, future directions, and challenges. .
    Type of Medium: Online Resource
    Pages: XV, 611 p. 155 illus., 117 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030507039
    URL: https://doi.org/10.1007/978-3-030-50703-9
    DOI: 10.1007/978-3-030-50703-9
    DDC: 615
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  • 44
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    Online Resource
    Antiviral Drug Discovery and Development (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Pharmacy. ; Biotechnology. ; Pharmacology. ; Pharmacy. ; Biotechnology.
    Description / Table of Contents: 1 Antiviral Drugs Against Herpesviruses -- 2 An Update on Antiretroviral Therapy -- 3 Structural Insights to Human Immunodeficiency Virus (HIV-1) Targets and their Inhibition -- 4 LEDGINs, Inhibitors of the Interaction between HIV-1 Integrase and LEDGF/p75, are Potent Antivirals with a Potential to Cure HIV Infection -- 5 Moving Fast Towards Hepatitis B Virus Elimination -- 6 Discovery and Development of Antiviral Therapies for Chronic Hepatitis C Virus Infection -- 7 Phytoconstituents as Lead Compounds for Anti-dengue Drug Discovery -- 8 Anti-influenza Drug Discovery and Development: Targeting the Virus and its Host by all -- 9 Search, Identification and Design of Effective Antiviral Drugs against Pandemic Human Coronaviruses -- 10 Peptide Based Antiviral Drugs -- 11 Covalent Antiviral Agents -- 12 Safe-in-Man Broad Spectrum Antiviral Agents -- 13 Exploiting Ubiquitin ligases for Induced Target Degradation as an Antiviral Strategy. .
    Abstract: This book summarizes state-of-the-art antiviral drug design and discovery approaches starting from natural products to de novo design, and provides a timely update on recently approved antiviral drugs and compounds in advanced clinical development. Special attention is paid to viral infections with a high impact on the world population or highly relevant from the public health perspective (HIV, hepatitis C, influenza virus, etc.). In these chapters, limitations associated with adverse effects and emergence of drug resistance are discussed in detail. In addition to classical antiviral strategies, chapters will be dedicated to discuss the non-classical drug development strategies to block viral infection, for instance, allosteric inhibitors, covalent antiviral agents, or antiviral compounds targeting protein–protein interactions. Finally, current prospects for producing broad-spectrum antiviral inhibitors will be also addressed. The book is distinctive in providing the most recent update in the rapidly evolving field of antiviral therapeutics. Authoritative reviews are written by international scientists well known for their contributions in their topics of research, which makes this book suitable for researchers not only within the antiviral research community but also attractive to a broad audience in the drug discovery field. This book covers molecular structures and biochemical mechanisms mediating the antiviral effects, while discussing various ligand design strategies, which include traditional medicinal chemistry, computational chemistry, and chemical biology approaches. The book provides a comprehensive review of antiviral drug discovery and development approaches, particularly focusing on current innovations and future trends.
    Type of Medium: Online Resource
    Pages: XI, 357 p. 142 illus., 64 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811602672
    Series Statement: Advances in Experimental Medicine and Biology, 1322
    URL: https://doi.org/10.1007/978-981-16-0267-2
    DOI: 10.1007/978-981-16-0267-2
    DDC: 615
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  • 45
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    Voltage-gated Ca2+ Channels: Pharmacology, Modulation and their Role in Human Disease (2023)
    Cham :Springer International Publishing :
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    Keywords: Pharmacology. ; Medical genetics. ; Human physiology. ; Pharmacology. ; Medical Genetics. ; Human Physiology.
    Description / Table of Contents: Preface -- Part 1 Modulation -- Cav1.1Calcium Channel Signaling Complexes in Excitation–Contraction Coupling: Insights from Channelopathies -- Mechanisms of Vascular CaV1.2 Channel Regulation During Diabetic Hyperglycemia -- Sympathetic Nervous System Regulation of Cardiac Calcium Channels -- Modulation of CaV1.2 Channel Function by Interacting Proteins and Post-Translational Modifications: Implications in Cardiovascular Diseases and COVID-19 -- Part 2 Pharmacological Approaches -- Pathophysiological Roles of Auxiliary Calcium Channel α2δ Subunits -- Design and Applications of Genetically-Encoded Voltage-Dependent Calcium Channel Inhibitors -- Part 3 Disease insight from channelopathies: consequences for pharmacology and therapeutic strategies -- CACNA1C-Related Channelopathies -- CACNA1D-Related Channelopathies: From Hypertension to Autism -- CACNA1A-Related Channelopathies: Clinical Manifestations and Treatment Options -- CaV3.2 (CACNA1H) in Primary Aldosteronism,- CaV3.3 Channelopathies -- Pathophysiological Roles of Auxiliary Calcium Channel α2δ Subunits.
    Abstract: The aim of this volume is to summarize novel findings on the function, pathophysiology, and regulation of voltage-gated Ca2+ channels and on novel concepts of their pharmacological modulation. Impressive insights into the role of channel function and regulation have come from Ca2+ channelopathies affecting the pore-forming as well as accessory subunits and channel-interacting proteins. Moreover, the long-sought molecular basis for key regulatory pathways have been discovered as well as exciting concepts of their subtype-selective pharmacological modulation.
    Type of Medium: Online Resource
    Pages: XII, 316 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031384370
    Series Statement: Handbook of Experimental Pharmacology, 279
    URL: https://doi.org/10.1007/978-3-031-38437-0
    DOI: 10.1007/978-3-031-38437-0
    DDC: 615
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  • 46
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    Edible Plants in Health and Diseases : Volume II : Phytochemical and Pharmacological Properties (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Food science. ; Medicinal chemistry. ; Pharmacology. ; Food Science. ; Medicinal Chemistry.
    Description / Table of Contents: 1 Zingiber officinale - Its Ethanobotanical Uses, Phytochemistry and Pharmacology -- 2 An Insight in to the Phytochemistry, Traditional uses and Pharmacology of Ziziphus spina-christi (L) Willd. (Sidr): An Edible wild plant of Arabian Peninsula -- 3 Traditional Uses, Phytochemistry and Pharmacological Profile of Salvadora persica Linn -- 4 Phytochemistry, Pharmacology and Applications of Ocimum sanctum (Tulsi) -- 5 Nigella sativa: Its Ethnobotany, Phytochemistry and Pharmacology -- 6 A Review on Ethnomedicinal, Phytochemistry and Pharmacological Activities of Rumex hastatus D. Don -- 7 Chemical Composition and Biological Uses of Crocus sativus L.(Saffron) -- 8 Positive Health Benefits of Saponins from Edible Legumes: Phytochemistry and Pharmacology -- 9 Taraxcum officinale: The Esculent Dandelion as Herbal Medicine -- 10 Arctium lappa: A Review on its Phytochemistry and Pharmacology -- 12 Cichorium intybus: A Comprehensive Review on its Pharmacological Activity and Phytochemistry -- 13 Phytochemical and Pharmacological Properties of Picrorhiza kurroa -- 14 Lady's Purse (Capsella bursa-pastoris L.)-Current perspective on its ethanopharmacological, therapeutic potential and phytochemistry -- 15 Ethnopharmaology, Phytochemistry and Biological Activities of Achillea millefolium: A Comprehensive Review -- 16 A Review on Traditional Uses, Phytochemistry and Pharmacological Activities of Verbascum thapsus -- 17 Acorus calamus - A Review on Its Phytochemical and Pharmacological Profile.
    Abstract: The book provides essential information on some of the promising edible medicinal plants and how these possess both nutritional as well as therapeutic value. The significance of the edible plants in traditional medicine and the importance of the distribution of their chemical constituents are discussed systematically concerning the role of these plants in ethnomedicine in different regions of the world. The current volume deals with the individual plants' phytochemical and pharmacological properties, emphasizing human health. The title would demonstrate the value of natural edible plants and introduce readers to state-of-the-art developments and trends in omics-driven research. This book is a single-source scientific reference to explore the specific factors that contribute to these potential health benefits and discuss how to maximize those potential benefits. Chemists, food technologists, pharmacologists, phytochemists, and all professionals involved with quality control and standardization will find in this book a valuable and updated basis for their work.
    Type of Medium: Online Resource
    Pages: IX, 522 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811649592
    URL: https://doi.org/10.1007/978-981-16-4959-2
    DOI: 10.1007/978-981-16-4959-2
    DDC: 615
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  • 47
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    The Kappa Opioid Receptor (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Pharmacology.
    Description / Table of Contents: From the contents. Preface.-Part I: Molecular aspects of KOR -- Part II: Preclinical research on pharmacology of KOR agonists and antagonists in animals -- Part III: KOR agonists and antagonists in clinical use and in past and present clinical trials.
    Abstract: This book covers the latest knowledge in structure, signaling, and biochemical pharmacology of KOR as well as preclinical research and clinical applications (including clinical phase studies and approved for human use) of KOR compounds. It is divided up into the three parts: Molecular aspects of KOR, Preclinical research on pharmacology of KOR agonists and antagonists in animals and KOR agonists and antagonists in clinical use and in past and present clinical trials. The chapters "Biosensors monitor ligand-selective effects at kappa opioid receptors" and "The role of dynorphin and the kappa opioid receptor in schizophrenia and major depressive disorder: a translational approach" of this book are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Type of Medium: Online Resource
    Pages: XI, 577 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030890742
    Series Statement: Handbook of Experimental Pharmacology, 271
    URL: https://doi.org/10.1007/978-3-030-89074-2
    DOI: 10.1007/978-3-030-89074-2
    DDC: 615
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  • 48
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    Behavioral Neurobiology of GABAB Receptor Function (2022)
    Cham :Springer International Publishing :
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    Keywords: Pharmacology. ; Neurosciences. ; Psychiatry. ; Pharmacology. ; Neuroscience. ; Psychiatry.
    Abstract: It has been almost forty years since Norman G. Bowery discovered and named this “non-GABAA” receptor the GABAB receptor. It has been almost ten years since the last comprehensive book presentation focused on GABAB receptors. The main goal of this book is to provide the field with a contemporary and comprehensive perspective on the GABAB receptor, its physiological relevance, and its therapeutic potential. The volume is organized into introductory and special interest sections presented by experts who study the GABAB receptor from structural, signaling, pharmacologic, physiological, pathophysiological, and therapeutic perspectives. The book aims to appeal to a broad spectrum of biomedical and clinical scientists - any scholars with an interest in GABAB receptor. The editors hope readers find this work to be thought-provoking, instructive, and informative.
    Type of Medium: Online Resource
    Pages: VII, 329 p. 70 illus., 15 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030913359
    Series Statement: Current Topics in Behavioral Neurosciences, 52
    URL: https://doi.org/10.1007/978-3-030-91335-9
    DOI: 10.1007/978-3-030-91335-9
    DDC: 615
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  • 49
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    Marine Biomaterials : Drug Delivery and Therapeutic Applications (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Medicine Research. ; Biology Research. ; Biomaterials. ; Pharmacy. ; Biomedical engineering. ; Pharmacology. ; Biomedical Research. ; Biomaterials. ; Pharmacy. ; Translational Research. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: Chapter 1. Marine biopolymers for oral delivery of drug -- Chapter 2. Marine polymer based nanocarriers for drug delivery application -- Chapter 3. Alginate: A promising biopolymer in drug delivery system -- Chapter 4. Chitosan Based Nanocomposite as Targeted drug delivery Carrier -- Chapter 5. Marine Biopolymer Based Oral In situ Gel: Drug Delivery Applications -- Chapter 6. Marine biopolymers for transdermal drug delivery -- Chapter 7. Marine polysaccharides for skin drug delivery: hydrogels and microneedles solutions -- Chapter 8. Marine collagen: promising biomaterial in delivery of therapeutics for cancer therapy -- Chapter 9. Chitosan based gel for ocular drug delivery. Chapter 10. Marine based biopolymers for central nervous system drug delivery -- Chapter 11. Marine Biopolymers Based Anticancer Drug Delivery Systems -- Chapter 12. Marine-Derived polysaccharides: prospects for future pharmaceuticals and drug delivery systems.
    Abstract: This book is focused on marine based biomedical carriers for delivery of therapeutics. Marine biomaterials and bio-based carriers show wide applications in pharmaceutical as well as biomedical fields for delivery of small and large molecules. Biomaterial-based composites, scaffolds or matrix systems are promising systems for controlled and prolonged release of drug in target site and control the premature release of drugs or bioactive compounds. This book discusses the targeted delivery of drugs and therapeutic applications. It also describes the use of marine biopolymers in cancer therapy. Different chapters describe the tissue engineering techniques to develop these carriers. The marine biomaterial-based systems are widely used for tissue engineering, and biomedical imaging. This book is meant for industry experts, students and researchers in the area of pharmaceutical sciences, biomedical engineering and material science and pharmacology.
    Type of Medium: Online Resource
    Pages: X, 453 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811647871
    URL: https://doi.org/10.1007/978-981-16-4787-1
    DOI: 10.1007/978-981-16-4787-1
    DDC: 615
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  • 50
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    Online Resource
    Parkinsonism and the Environment (2022)
    Cham :Springer International Publishing :
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    Keywords: Pharmacology. ; Neurosciences. ; Pharmacology. ; Neuroscience.
    Description / Table of Contents: Experimental evidence for pesticide contribution in the pathogenesis of Parkinsonism: an update -- Epidemiological evidence for pesticide involvement in the etiology of Parkinson’s Disease: current state of affairs?” -- Manganese induced Parkinsonism: cellular and molecular mechanisms -- Manganese overexposures in occupational and environmental settings and Parkinsonism: where do we stand -- Aberrant dopamine metabolism as a focal point in the mechanism of environmental contaminant-induced dopaminergic dysfunction -- Emerging contaminants as contributors to Parkinsonism: focus on PhiPs -- Emerging contaminants as contributors to Parkinsonism: focus on PhiPs -- Protein kinase C-delta (PKC-delta): a major molecular target for disparate dopaminergic toxicants -- Environmental contribution to redox dyshomeostasis in Parkinsonism.
    Abstract: “The book is comprised of individual reviews with the common goal of providing up-to-date state of the knowledge information on the role the environment plays in the pathogenesis of parkinsonism. The reviews focus on recent advances in the quest of deciphering the molecular and cellular mechanisms of parkinsonian dysfunction, highlight specific emerging dopaminergic toxicants and an alternative experimental model to study the link between environmental exposures and parkinsonism, and provide an update from epidemiological and experimental points of view related to the pesticide exposures and parkinsonism/Parkinson’s Disease association. Foremost experts in their respective fields are the senior authors on each chapter and the book fills a critical void that now exists as a book of similar nature has not been published in the last 15 years. Researchers and clinicians with an interest in Parkinson's Disease and related disorders, as well as toxicologists, graduate students, and the general public who are interested in the contribution of environmental factors to neurological dysfunction are among the readership for this book.”.
    Type of Medium: Online Resource
    Pages: V, 158 p. 14 illus., 8 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030874513
    Series Statement: Molecular and Integrative Toxicology,
    URL: https://doi.org/10.1007/978-3-030-87451-3
    DOI: 10.1007/978-3-030-87451-3
    DDC: 615
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  • 51
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    Ethnopharmacology and Drug Discovery for COVID-19: Anti-SARS-CoV-2 Agents from Herbal Medicines and Natural Products (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Natural products. ; Nanobiotechnology. ; Bioinformatics. ; Diseases Causes and theories of causation. ; Molecular biology. ; Pharmacology. ; Natural Products. ; Nanobiotechnology. ; Bioinformatics. ; Pathogenesis. ; Molecular Biology.
    Description / Table of Contents: 1. COVID-19: An overview of virology, mutations, pathology, epidemiology, diagnosis, preventions and treatments -- 2. The recent development of therapeutic strategies against COVID-19 -- 3. Plant immunoenhancers: Promising ethnopharmacological candidates for anti-SARS-CoV-2 activity -- 4. Herbal formulations in fighting against the SARS-CoV-2 infection -- 5. Rejuvenation of traditional medicine in the 21st century against SARS-CoV-2 -- 6. Traditional herbal medicines and their active constituents in combating SARS-CoV-2 infection -- 7. Antiviral phytocompounds against animal-to-human transmittable SARS-CoV-2 -- 8. Plants-derived bioactive compounds as potential ACE-2 inhibitors against SARS-CoV-2 infection -- 9. Insights into in silico methods to explore plant bioactive substances in combating SARS-CoV-2 -- 10. Dietary plants, spices and fruits in curbing SARS-CoV-2 virulence -- 11. Therapeutic potential of selected medicinal plants for neurological disorders after the infection of COVID-19 -- 12. Glycyrrhizae Radix et Rhizoma (Gan Cao) for the management of COVID-19 -- 13. COVID-19-induced kidney disease: Ethnopharmacological intervention to ameliorate kidney damage and improve kidney function -- 14. Phytochemicals and nutraceuticals targeting SARS-CoV-2: An in silico analysis -- 15. Therapeutic and prophylactic effects of plant derivatives against SARS-CoV-2 -- 16. Therapeutic potential of essential oils against SARS-CoV-2 infection -- 17. Antiviral properties of South Indian plants against SARS-CoV-2 -- 18. Immune-boosting plants used in Turkish folk medicine and their potential against COVID-19 -- 19. A comparison study of medicinal plants used against SARS-CoV-2 and those recommended against malaria in Africa -- 20. Exploring the potential antiviral properties of Nigella sativa L. against SARS-CoV-2: Mechanisms and prospects -- .
    Abstract: This book presents a complete overview of COVID-19 and provides a series of in-depth analyses of the literature and a comprehensive discussion and perspectives on promising anti-SARS-CoV-2 agents based on the system of ethnopharmacology, which covers Chinese medicine, traditional medicines of India and Africa, Turkish folk medicine, essential oils, and some well-known medicinal plants. In this book, the current status of therapeutic strategies against COVID-19 was summarized and a perspective of potential options for the future was proposed. Based on ethnopharmacology, some well-established traditional herbal formulations and bioactive compounds with anti-virus activity were repurposed for managing COVID-19 and post-illness, including neurological disorders and kidney illness. Using drug discovery tools, promising immune enhancers were explored from phytochemicals against SARS-CoV-2. Nutraceuticals from dietary plants, spices, and fruits with anti-virus and antioxidant activities were recommended to prevent infection or severe illness caused by emerging variants. With the aid of systems pharmacology, researchers have gained insights into possible molecular mechanisms of anti-SARS-CoV-2 activity and have predicted a range of candidate compounds from medicinal plants to combat COVID-19. This book explores the current knowledge of drug discovery and ethnopharmacology for managing coronavirus diseases. The content proved the anti-SARS-CoV-2 activity from natural products and traditional herbal medicines. It contributes to the management of global public health and fits the goal of establishing “Good Health and Well-Being,” which is one of “The Sustainable Development Goals (SDGs) 2030".
    Type of Medium: Online Resource
    Pages: IX, 590 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819936649
    URL: https://doi.org/10.1007/978-981-99-3664-9
    DOI: 10.1007/978-981-99-3664-9
    DDC: 615
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    Novel Drug Targets With Traditional Herbal Medicines : Scientific and Clinical Evidence (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Toxicology. ; Pharmaceutical chemistry. ; Medicinal chemistry. ; Natural products. ; Pharmacology. ; Toxicology. ; Pharmaceutics. ; Medicinal Chemistry. ; Natural Products.
    Description / Table of Contents: Chapter 1: Achillea biebersteinii Afan -- Chapter 2: Aesculus hippocastanum L. -- Chapter 3: Berberis crataegina DC. -- Chapter 4: Calendula officinalis L. -- Chapter 5: Camellia sinensis (L.) Kuntze -- Chapter 6: Capsella bursa-pastoris (L.) Medik. -- Chapter 7: Capsicum annuum L. -- Chapter 8: Cedrus libani A.Rich. -- Chapter 9: Chelidonium majus L. -- Chapter 10: Cichorium intybus L. -- Chapter 11: Cistus laurifolius L. -- Chapter 12: Coriandrum sativum L. -- Chapter 13: Cornus mas L. -- Chapter 14: Curcuma longa L..-Chapter 15: Cydonia oblonga Mill. -- Chapter 16: Cynara scolymus L. -- Chapter 17: Equisetum arvense L. -- Chapter 18: Foeniculum vulgare Mill. -- Chapter 19: Fraxiınus ornus L. -- Chapter 20: Fumaria officinalis L. -- Chapter 21: Helichrysum plicatum DC. -- Chapter 22: Hyoscyamus niger L. -- Chapter 23: Juglans regia L. -- Chapter 24: Laurus nobilis L. -- Chapter 25: Liquidambar orientalis Miller -- Chapter 26: Matricaria chamomilla L. -- Chapter 27: Melissa officinalis L. -- Chapter 28: Momordica charantia L. -- Chapter 29: Nigella sativa L. -- Chapter 30: Olea europaea L. -- Chapter 31: Papaver somniferum L. -- Chapter 32: Rheum ribes L. -- Chapter 33: Rosa canina L. -- Chapter 34: Rosmarinus officinalis L. -- Chapter 35: Silybum marianum L. Gaertn. -- Chapter 36: Urtica dioica L -- Chapter 37: Valeriana officinalis L. -- Chapter 38: Viburnum opulus L.
    Abstract: This book collects information about the most popular ethnomedicinal plants, which are common in Turkey and around the world. It presents the ethnopharmacological records, in vivo and in vitro studies, side effects, chemical compositions and clinical studies of these medicinal plants. Its special focus is on the novel drug targets for disease and their possible mechanisms of action. It covers botanical descriptions the status of the plants, and food or drug interactions including precautions and warnings about the plants and the available market products. It provides an explanation of recorded and known plant administration dosages. Also, the gap between the traditional practice and scientific/clinical evidences in the use of ethnomedicinal plant is acknowledged. It is well known that traditional knowledge of the use of the medicinal plants in therapy is an important resource for the discovery of novel treatment options and drug targets. The main purpose of this book is to draw attention to ethnomedicinal plant species. Data on the therapeutic potentials of these medicinal plants can now be accessed from a single source. It provides an important resource for future research opportunities for harnessing the full potential of these plants.
    Type of Medium: Online Resource
    Pages: XII, 588 p. 119 illus., 43 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031077531
    URL: https://doi.org/10.1007/978-3-031-07753-1
    DOI: 10.1007/978-3-031-07753-1
    DDC: 615
    Language: English
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    Online Resource
    Herb-Drug Combinations : A New Complementary Therapeutic Strategy (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Pharmacy. ; Alternative medicine. ; Pharmacovigilance. ; Medicinal chemistry. ; Pharmacology. ; Pharmacy. ; Complementary and Alternative Medicine. ; Drug Safety and Pharmacovigilance. ; Medicinal Chemistry.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. Measuring Herb-drug interaction and Synergy -- Chapter 3. Herb-Herb and Food-drug interactions -- Chapter 4. Pharmacokinetic interactions in synergistic herb-drug combinations -- Chapter 5. Antagonistic Herb-drug interactions -- Chapter 6. Synergistic Herb-drug interactions against bacteria -- Chapter 7. Synergistic herb-drug interactions against tuberculosis -- Chapter 8. Synergistic herb-drug interactions against viral diseases -- Chapter 9. Synergistic herb interactions with cardiovascular drugs -- Chapter 10. Synergistic herb interactions with anticancer drugs -- Chapter 11. Synergistic herb interactions with antidiabetic drugs -- Chapter 12. Synergistic herb-drug interactions against obesity -- Chapter 13. Synergistic Herb-Drug Interactions in Neurological Disorders -- Chapter 14. Synergistic Herb-drug interactions with antifungal and antiparasitic agents -- Chapter 15. Computational methods to study herb-drug interactions -- Chapter 16. Regulations and guidelines involving synergistic plant-drug interactions -- Chapter 17. Clinical trials on synergistic herb-drug interactions -- Chapter 18. QFuture prospects on synergistic herb-drug interactions -- Chapter 19. Conclusion.
    Abstract: Plant extracts or their pure natural constituents have been used traditionally for thousands of years for treating diseases with considerable success in India and other Asian countries. In addition, they have also been used as complements or supplements with conventional medicine. This book discusses the latest research in the application of combination therapy, namely herbs and drugs, in the treatment of a range of communicable and non-communicable diseases to achieve a synergistic effect. This synergy may help in reducing the amount of drug, its toxicity, side effects, and development of resistance as well as improve its efficacy. The book also discusses the pharmacodynamic and pharmacokinetic parameters, experimental tools to determine the impact of combination, computational approaches to identify synergy, statistical analysis of data, and clinical and regulatory issues. The book is useful for researchers in the fields of pharmacology, pharmacy and medicinal chemistry and those working in pharmaceutical and nutraceutical industries. This book could open up new strategies to focus on multiple targets to combat complex diseases unlike the single targeted drugs that are being currently marketed by the pharmaceuticals industries.
    Type of Medium: Online Resource
    Pages: XV, 276 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811951251
    URL: https://doi.org/10.1007/978-981-19-5125-1
    DOI: 10.1007/978-981-19-5125-1
    DDC: 615
    Language: English
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    Sex and Gender Effects in Pharmacology (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Immunology. ; Neurology . ; Endocrinology. ; Cardiology. ; Pharmacology. ; Immunology. ; Neurology. ; Endocrinology. ; Cardiology.
    Description / Table of Contents: Part 1 Pharmacological Basic Principles -- The impact of sex and gender in medicine and pharmacology -- Sex differences in pharmacokinetics -- Clinical pharmacological considerations in transgender medicine -- Sex and gender differences in the pharmacology of the overactive urinary bladder -- Part 2 Pathologies of the Brain -- Sex differences in the evaluation and treatment of stroke -- Sex differences in pain and its treatment -- Therapeutics For Substance-Using Women: The Need To Elucidate Sex-Specific Targets For Better-Tailored Treatments -- Intersection of sex and depression: pathogenesis, presentation and treatments -- Biological and clinical implications of sex-specific differences in Alzheimer’s disease -- Part 3 Diabetes, metabolic diseases & cardiovascular risk -- Gender Differences In Cardiovascular Health: Hormonal Effects on Cardiovscular Risk And Management. - Sex Differences in Glucose Homeostasis -- Sex-gender-based differences in metabolic diseases -- Hypothalamic pituitary gonadal axis disorders impacting fertility in both sexes and the potential of kisspeptin-based therapies to treat them.
    Abstract: Biological sex and gender have a tremendous impact on the efficacy and safety of pharmacological interventions in virtually every disease state. This book presents a comprehensive and up-to-date overview on how sex-specific information is guiding the diagnosis and treatment of diseases affecting men and women, as well as of disease states that disproportionally affects women. Experts in various fields discuss both preclinical and clinical research that is contributing to a better understanding of the impact of sex in the presentation, etiology, treatment, and disease outcomes. Also discussed are the challenges encountered in implementing this growing body of knowledge into practice, as well as possible avenues to recognize and reduce health disparities between men and women so that therapeutic interventions are tailored and improved.
    Type of Medium: Online Resource
    Pages: VIII, 288 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031426483
    Series Statement: Handbook of Experimental Pharmacology, 282
    URL: https://doi.org/10.1007/978-3-031-42648-3
    DOI: 10.1007/978-3-031-42648-3
    DDC: 615
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    Transformation Processes of Metals in Urban Road Dust : Implications for Stormwater Reuse (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pollution. ; Water. ; Hydrology. ; Engineering geology. ; Pollution. ; Water. ; Geoengineering.
    Description / Table of Contents: Chapter 1: Metals in urban stormwater environments -- Chapter 2: Research design -- Chapter 3: Metal transformation and stormwater quality -- Chapter 4: Risk evaluation based on the metal transformation and bioavailability -- Chapter 5: Practical implications and recommendation for future research -- Appendices -- Index.
    Abstract: This book discusses the physicochemical changes (transformations) that metals deposited on urban road surfaces undergo during dry weather periods, in order to provide insights into their potential impacts on stormwater quality. Based on extensive field experiments, and laboratory and data analyses, it examines transformation characteristics of metals with respect to the particle size of road dust, antecedent dry days and land uses. Further, it proposes a new risk-assessment methodology, improving the original human health-risk indices based on the transformation characteristics and potential bioavailability of metals in order to evaluate the risks posed by metals in stormwater. This book is of interest to researchers and decision-makers developing appropriate pollution mitigation measures to enhance the quality of stormwater, targeting the effective reuse of stormwater in urban areas.
    Type of Medium: Online Resource
    Pages: VI, 50 p. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811520785
    Series Statement: SpringerBriefs in Water Science and Technology,
    URL: https://doi.org/10.1007/978-981-15-2078-5
    DOI: 10.1007/978-981-15-2078-5
    DDC: 363.73
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    Empty Buckets and Overflowing Pits : Urban Water and Sanitation Reforms in Sub-Saharan Africa – Acknowledging Decline, Preparing for the Unprecedented Wave of Demand (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pollution. ; Refuse and refuse disposal. ; Sociology, Urban. ; Economic policy. ; Developmental psychology. ; Medical sciences. ; Pollution. ; Waste Management/Waste Technology. ; Urban Sociology. ; Economic Policy. ; Developmental Psychology. ; Health Sciences.
    Description / Table of Contents: Part 1: Urban Water and Sanitation (W+S) - Separating fiction from reality -- Chapter 1. Introduction to urban W+S in the developing world -- Chapter 2. Considerations for general W+S issues -- Chapter 3. Beyond the usual debate -- PART 2: Design and validation of the sector development model -- Chapter 4. An effective orientation and approach for development -- Chapter 5. What sector reforms in four countries teach us? -- Chapter 6. Reasons for the different reform outcomes in the four countries -- Part 3: At least full buckets and clear pits on the way forward -- Chapter 7. Ending the ‘urban W+S divide’ by serving the poor -- Chapter 8. Conclusions: The quintessence of W+S sector reforms in Sub-Saharan Africa -- Chapter 9. Recommendations: Guidance to master the coming wave of challenges.
    Abstract: This book provides a multi-level and multi-dimensional insight into urban water and sanitation development by analyzing sector reforms in Africa. With the recent events in mind - water shortages in Cape Town, widespread cholera in Haiti, mass-migration from low-income countries, etc. – it elaborates a pressing topic which is directly linked to the precarious living conditions of the urban poor in the developing countries. It is urgent to acknowledge the proposed findings and recommendations of the book which will help to improve the situation of potential refugees in their home countries with a realistic vision for the development of the most basic of all life supporting services. So many efforts to reverse the negative trend in water and sanitation development have failed or targets have been repeatedly missed by far without notable consequences for decision makers on different levels and institutions. It has unnecessarily consumed many young lives, contributed to keep billions in poverty until today and fostered discrimination of women. The knowledge gap and the confusion in the sector lined out in the book becomes evident when a national leader in a low-income country declares a state of emergency in urban water and sanitation while at the same time global monitoring publishes an access figure for urban water of over 90% for the same country. It is time to change this with an effective sector development concept for our partner countries and a more realistic discourse on global level. The book argues for a sweeping rethinking and combines extended local knowledge, lessons learned from history in advanced countries and thorough research on reforms in Francophone and Anglophone developing countries. This was possible because the writer was working in Sub-Saharan partner countries for almost 30 years as an integrated long term advisor in different sector institutions (ministry, regulator, financing basket and different sizes of utilities) and had the opportunity to cooperate closely with the main development partners. The reader has the opportunity to obtain a comprehensive understanding of how the sector works and sector institutions in low-income countries function and can discover the reasons behind success and failures of reforms. The book also covers issues which have a significant influence on urban water and sanitation development but are hardly the subject of discussions. It helps to make the shortcomings of the water and sanitation discourse more apparent and assist institutions to move beyond their present perceptions and agendas. All of this makes the book different from other literature about urban water and sanitation in the developing world.
    Type of Medium: Online Resource
    Pages: XXII, 285 p. 24 illus., 3 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030313838
    Series Statement: Springer Water,
    URL: https://doi.org/10.1007/978-3-030-31383-8
    DOI: 10.1007/978-3-030-31383-8
    DDC: 363.73
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    Technological and Modern Irrigation Environment in Egypt : Best Management Practices & Evaluation (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pollution. ; Agriculture. ; Environmental management. ; Environment. ; Geographic information systems. ; Sustainability. ; Pollution. ; Agriculture. ; Environmental Management. ; Environmental Sciences. ; Geographical Information System. ; Sustainability.
    Description / Table of Contents: An Overview of Modern Irrigation system in Egypt -- Irrigation: Water Resources, Types and Common Problems in Egypt -- Need for Irrigation System Evaluation -- Evolution of irrigation system, tools and Technologies -- Smart Sensing System for Precision Irrigation -- Development of Recent Information on Irrigation Technology and Management.
    Abstract: This book gathers contributions on modern irrigation environments in Egypt from an environmental and agricultural perspective. Written by leading experts in the field, it discusses a wide variety of modern irrigation problems. In the context of water resources management in Egypt, one fundamental problem is the gap between growing water demand and limited supply. As such, improving irrigation systems and providing farmers with better control over water are crucial to increasing productivity. The book presents state-of-the-art technologies and techniques that can be effectively used to address a range of problems in modern irrigation, as well as the latest research advances. Focusing on water sensing and information technologies, automated irrigation technologies, and improved irrigation efficiency. It brings together a team of experts who share their personal experiences, describe the various applications, present recent advances, and discuss possibilities for interdisciplinary collaboration and implementing the techniques covered.
    Type of Medium: Online Resource
    Pages: X, 369 p. 66 illus., 45 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030303754
    Series Statement: Springer Water,
    URL: https://doi.org/10.1007/978-3-030-30375-4
    DOI: 10.1007/978-3-030-30375-4
    DDC: 363.73
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    Water Quality Index Prediction Using Multiple Linear Fuzzy Regression Model : Case Study in Perak River, Malaysia (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pollution. ; Water. ; Hydrology. ; Computational intelligence. ; Pollution. ; Water. ; Computational Intelligence.
    Description / Table of Contents: Introduction -- Fuzzy Multiple Linear Regression -- Water Quality Index (WQI) -- Data Collection and Study Sites -- Water Quality Index Using Fuzzy Regression.
    Abstract: This book addresses the prediction of the Water Quality Index (WQI) at Perak River, State of Perak, Malaysia, using a fuzzy multiple linear regression model to tackle the uncertainty in the measurements of six key parameters – dissolved oxygen (DO), biological oxygen demand (BOD), chemical oxygen demand (COD), suspended solids (SS), pH value (pH) and ammoniacal nitrogen (NH3-NL). Given its scope, the book is suitable for graduate students, researchers and water quality scientists.
    Type of Medium: Online Resource
    Pages: XII, 55 p. 18 illus., 16 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811534850
    Series Statement: SpringerBriefs in Water Science and Technology,
    URL: https://doi.org/10.1007/978-981-15-3485-0
    DOI: 10.1007/978-981-15-3485-0
    DDC: 363.73
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    Microbial Bioremediation & Biodegradation (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pollution. ; Environmental chemistry. ; Environmental engineering. ; Biotechnology. ; Bioremediation. ; Environmental health. ; Pollution. ; Environmental Chemistry. ; Environmental Engineering/Biotechnology. ; Environmental Health.
    Description / Table of Contents: Chapter 1. Bioremediation Approaches for Treatment of Pulp and Paper Industry Wastewater: Recent Advances and Challenges -- Chapter 2. Microbial remediation of Heavy Metals -- Chapter 3. Dyes: Effect on the Environment and Biosphere and Their Remediation Constraints -- Chapter 4. Microbial Bioremediation and Biodegradation of Hydrocarbons, Heavy Metals, and Radioactive Wastes in Solids and Wastewaters -- Chapter 5. Advancement of Omics: Prospects for Bioremediation of Contaminated Soils -- Chapter 6. Microbial Biotransformation of Hexavalent Chromium [Cr(VI)] in Tannery Wastewater -- Chapter 7. Bioremediation: A Low-Cost and Clean-Green Technology for Environmental Management -- Chapter 8. Microbial Degradation of Pharmaceuticals and Personal Care Products from Wastewater -- Chapter 9. Extremophiles: A Powerful Choice for Bioremediation of Toxic Oxyanions -- Chapter 10. Conventional and Nonconventional Biodegradation Technologies for Agro-Industrial Liquid Waste Management -- Chapter 11. White Rot Fungi: Nature’s Scavenger -- Chapter 12. Nanobioremediation: An Emerging Approach for a Cleaner Environment -- Chapter 13. Bioelectrochemical System for Bioremediation and Energy Generation -- Chapter 14. Ligninolysis: Roles of Microbes and Their Extracellular Enzymes -- Chapter 15. Biosorption of Heavy Metals by Cyanobacteria: Potential of Live and Dead Cells in Bioremediation -- Chapter 16. Bioremediation of pharmaceuticals in water and wastewater -- Chapter 17. Bioremediation Of Saline Soil by Cyanobacteria -- Chapter 18. Advancement in Treatment Technologies of Biopharmaceutical Industrial Effluents.-Chapter 19. Marine Bacteria: A Storehouse of Novel Compounds for Biodegradation -- Chapter 20. Energy-Efficient Anaerobic Ammonia Removal: From Laboratory to Full-Scale Application -- Chapter 21. Microbial Degradation of Natural and Synthetic Rubbers.-.
    Abstract: Microbial or biological degradation has long been the subject of active concern, and the rapid expansion and growing sophistication of various industries in the last century has significantly increased the volume and complexity of toxic residues of wastes. These can be remediated by plants and microbes, either natural origin or adapted for a specific purpose, in a process known as bioremediation. The interest in microbial biodegradation of pollutants has intensified in recent years in an attempt to find sustainable ways to clean contaminated environments. These bioremediation and biotransformation methods take advantage of the tremendous microbial catabolic diversity to degrade, transform or accumulate a variety of compounds, such as hydrocarbons, polychlorinated biphenyls, polaromatic hydrocarbons pharmaceutical substances, radionuclides and metals. Unlike conventional methods, bioremediation does not physically disturb the site. This book describes the basic principles of biodegradation and shows how these principles are related to bioremediation. Authored by leading, international environmental microbiologists, it discusses topics such as aerobic biodegradation, microbial degradation of pollutants, and microbial community dynamics. It provides valuable insights into how biodegration processes work and can be utilised for pollution abatement, and as such appeals to researchers and postgraduate students as well as experts in the field of bioremediation.
    Type of Medium: Online Resource
    Pages: IX, 550 p. 69 illus., 48 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811518126
    URL: https://doi.org/10.1007/978-981-15-1812-6
    DOI: 10.1007/978-981-15-1812-6
    DDC: 363.73
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    Atmospheric Reactive Nitrogen in China : Emission, Deposition and Environmental Impacts (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pollution. ; Environmental health. ; Sustainability. ; Biotic communities. ; Biodiversity. ; Pollution. ; Environmental Health. ; Sustainability. ; Ecosystems. ; Biodiversity.
    Description / Table of Contents: Chapter 1 Overview of atmospheric reactive nitrogen in China from a global perspective -- Part I Reactive nitrogen emission and deposition in China -- Chapter 2 Anthropogenic emissions of SO2, NOx and NH3 emissions in China -- Chapter 3 Monitoring nitrogen deposition in China -- Chapter 4 Modelling nitrogen deposition in China -- Chapter 5 Reactive nitrogen budgets in China -- Part II Contribution of atmospheric reactive nitrogen to China’s air pollution -- Chapter 6 Contribution of atmospheric reactive nitrogen to haze pollution in China -- Chapter 7 Contribution of reactive nitrogen to ozone pollution in China -- Chapter 8 Contribution of atmospheric nitrogen to acid deposition in China -- Part III Impacts of nitrogen deposition on China’s ecosystems Chapter 9 Impacts of nitrogen deposition on forest ecosystems in China -- Chapter 10 Impact of nitrogen deposition on China’s grassland ecosystems -- Chapter 11 Impact of nitrogen deposition on China’s desert ecosystems -- Chapter 12 Impact of nitrogen deposition on China’s lake ecosystems: Taking Lake Dianchi as an example -- Part IV Reactive N Regulation Chapter 13 Nitrogen regulation in China’s agricultural systems -- Chapter 14 National regulation of SO2 and NOX emissions in China.
    Abstract: Atmospheric reactive nitrogen (N) emissions, as an important component of global N cycle, have been significantly altered by anthropogenic activities, and consequently have had a global impact on air pollution and ecosystem services. Due to rapid agricultural, industrial, and urban development, China has been experiencing an increase in reactive N emissions and deposition since the late 1970s. Based on a literature review, this book summarizes recent research on: 1) atmospheric reactive N in China from a global perspective (Chapter 1); 2) atmospheric reactive N emissions, deposition and budget in China (Chapters 2-5); 3) the contribution of atmospheric reactive N to air pollution (e.g., haze, surface O3, and acid deposition) (Chapters 6-8); 4) the impacts of N deposition on sensitive ecosystems (e.g., forests, grasslands, deserts and lakes) (Chapters 9-12); and 5) the regulatory strategies for mitigation of atmospheric reactive N pollution from agricultural and non-agricultural sectors in China (Chapters 13-14). As such it offers graduate students, researchers, educators in agricultural, ecological and environmental sciences, and policy makers a glimpse of the environmental issues related to reactive N in China .
    Type of Medium: Online Resource
    Pages: XVII, 331 p. 99 illus., 72 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811385148
    URL: https://doi.org/10.1007/978-981-13-8514-8
    DOI: 10.1007/978-981-13-8514-8
    DDC: 363.73
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    Water Availability and Management in Mexico (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pollution. ; Statistics . ; Geology. ; Geographic information systems. ; Pollution. ; Statistics in Engineering, Physics, Computer Science, Chemistry and Earth Sciences. ; Geology. ; Geographical Information System.
    Description / Table of Contents: 1. Preface -- 2. Acknowledgment -- 3. Part I: Water Availability 1 Overview of the water condition in México -- 4. 2 Hydrological watersheads in Mexico. Division and legal definition -- 5. 3 The Groundwater condition in Mexico -- 6. 4 Runoff simulation under future climate change and uncertainty -- 7. 5 Hydraulic fracking of not conventional reservoirs in Mexico: The issue of water and waste control -- 8. Part II. Water Quality 6 Pollution in wastewater used for irrigation in the Mezquital Valley, México: case study -- 9. 7 Mining industry in Mexico: Recycling of flotation effluents to the process using anaerobic sulfate-reducing consortia in UASB reactors for the elimination dissolved metals -- 10. 8 Water body trophic state determinations. Case study Tecocomulco lagoon, Hidalgo, Mexico -- 11. 9 Water quality management for a sustainable supply. The diagnosis of the State of San Luis Potosi, Mexico -- 12. 10 The wetland of Cajititlán Lake severely deteriorated and in danger of dying out -- 13. 11 Water quality of the Nexapa River: a diagnosis -- 14. 12 Impacts on the groundwater quality that supplies the Puebla City by the effect of aquifer intensive exploitation -- 15. Part III: Water Allocation 13 Water resources allocation with supply and demand uncertainties -- 16. 14 An overview of aquaculture activity in Hidalgo state -- 17. 15 Drinking Water Services Situation by the Region in the State of Nuevo León, Mexico -- 18. 16 Population and tourism dynamics, its effects on the future demand for water. Case study from Los Cabos, Baja California Sur -- 19/ Part IV: Water Governance 17 Water governance in 16 Mexican National Parks -- 20. 18 Conflict in border condition: the dispute over the use of water in the Mexicali valley -- 21. 19 The institutional challenges of the municipalities of Zacatecas in the wastewater treatment -- 22. Part V: Water Management 20 The institutional challenges of the municipalities of Zacatecas in the wastewater treatment -- 23. 21 Improving environmental services of Candelaria River basin by restoring ecological connectivity -- 24. 22 Transdisciplinary approach to assessing socio-hydrological resilience in urban metropolitan environments: a Mexican perspective -- 25. 23 The 80% paradigm: An appointment with the sewage in Cuernavaca.
    Abstract: This book presents several complex case studies related to water management and planning in the context of pollution, growing demands, and global climate change in Mexico, but which are also relevant for other countries in Latin America. These concerns are of critical importance for policymakers who are coping with multiple conflicting interests. Water availability in Mexico is polarized, with abundant rainfall and large rivers in the south, and desert-like conditions in the north. The central region, which is the most industrialized, is overpopulated. Mexico City pours millions of cubic meters of “blackwater” into the northern valley daily and receives its clean water from the south. To address these unsustainable conditions, the world's 4th biggest water treatment plant went into operation in 2018. The water infrastructure and governance must satisfy the demands of all sectors, including agricultural, urban, and economic activities. At the same time, water resources are affected by drought, and climate change puts constraints on the supply. As such, regulation and monitoring are important when it comes to adherence to agreed plans and priorities. The book is divided into four sections. 1: Water Availability discusses quantitative aspects, such as supply, methods of calculation, and fracking. 2: Water Quality highlights pollution risks and diagnosis of water resources. 3: Water Allocation examines the sectoral demands and vulnerability due to unsustainable irrigation. 4: Water Management and Governance focuses on laws, urban rules, national parks, planning, and integrated water resources management, among other topics. The chapters include illustrative case studies in Mexico, such as basins, cities, reservoirs, and aquifers, water supply demand assessment, planning, and management.
    Type of Medium: Online Resource
    Pages: X, 516 p. 155 illus., 108 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030249625
    Series Statement: Water Science and Technology Library, 88
    URL: https://doi.org/10.1007/978-3-030-24962-5
    DOI: 10.1007/978-3-030-24962-5
    DDC: 363.73
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    The African Marine Litter Outlook (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Pollution. ; Refuse and refuse disposal. ; Water. ; Hydrology. ; Africa Economic conditions. ; Oceanography. ; Sustainability. ; Pollution. ; Waste Management/Waste Technology. ; Water. ; African Economics. ; Ocean Sciences. ; Sustainability.
    Description / Table of Contents: Chapter 1. Introduction to Marine Litter in Africa -- Chapter 2. Marine litter sources and distribution pathways -- Chapter 3. Impacts and Threats of Marine Litter to Africa Chapter -- Chapter 4. Legal and Policy Frameworks to address marine litter through improved livelihoods -- Chapter 5. The way forward, building upon-the-ground innovation.
    Abstract: This open access book provides a cross-sectoral, multi-scale assessment of marine litter in Africa with a focus on plastics. From distribution, to impacts on environmental and human health, this book looks at what is known scientifically. It includes a policy analysis of the instruments that currently exist, and what is needed to help Africa tackle marine litter—including local and transboundary sources. Across 5 chapters, experts from Africa and beyond have put together a summary of the scientific knowledge currently known about marine litter in Africa. The context of the African continent and future projections form a backdrop on which the scientific knowledge is built. This scientific knowledge incorporates quantities, distributions, and pathways of litter into the marine environment, highlighting where the impacts of marine litter are most felt in Africa. These impacts have widespread effects, with ecological, social, economic, and human health repercussions. While containing detailed scientific information, this book provides a sound knowledge base for policymakers, NGOs and the broader public.
    Type of Medium: Online Resource
    Pages: XXII, 224 p. 33 illus., 29 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031086267
    URL: https://doi.org/10.1007/978-3-031-08626-7
    DOI: 10.1007/978-3-031-08626-7
    DDC: 363.73
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    Fresh Water Pollution Dynamics and Remediation (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pollution. ; Water. ; Hydrology. ; Environmental engineering. ; Biotechnology. ; Bioremediation. ; Freshwater ecology. ; Marine ecology. ; Pollution. ; Water. ; Environmental Engineering/Biotechnology. ; Freshwater and Marine Ecology.
    Description / Table of Contents: The Concerns for Global Sustainability of Freshwater Ecosystems -- Freshwater Pollution: Effects on Aquatic Life and Human Health -- Freshwater contamination: sources and hazards to aquatic biota -- Correlation Between Pollution Trends of Freshwater Bodies and Bacterial Disease of Fish Fauna -- Impact of Pollution on Quality of Freshwater Ecosystems -- Heavy metal intrusion and accumulation in aquatic ecosystems -- Impact of climate change on freshwater ecosystem and its sustainable management -- Role of biotools in restoration of freshwater ecosystems Bioremediation -- A Sustainable and Emerging Tool for Restoration of Polluted Aquatic Ecosystems -- Biosorption as Environmentally Friendly Technique for Heavy Metal Removal from Wastewater -- Biotechnological interventions as an aquatic clean up tool -- Analysis of hydrology, sediment retention, biogenic-calcification and -scavenging as self-remediative lacustrine functions -- Remediation of pesticides through microbial and phytoremediation techniques -- Trends in Phyto-management of Aquatic Ecosystems and Evaluation of Factors Affecting Removal of Inorganic Pollutants from Water Bodies -- Urban Pond Ecosystems: Preservation and Management Through Phytoremediation -- Aquatic Pollution Stress and Role of Biofilms as Environment Cleanup Technology -- Wonders of Nanotechnology for Remediation of Polluted Aquatic Environs.
    Abstract: Freshwater is a finite resource and is being deteriorated directly and indirectly by anthropogenic pressures. Preserving the quality and availability of freshwater resources is becoming one of the most pressing environmental challenges on the international horizon. To ensure the preservation as well as availability of freshwater resources, there is a need to understand the ecology of the freshwater systems, pollution problems, their impacts, restoration techniques to be opted and the conservation measures. In this backdrop the present book on ‘Freshwater Pollution Dynamics and Remediation’ has been compiled. The book provides an understanding about the present state of art, pollution impacts including the changes in the environmental quality as well as the shift in the aquatic biological communities of the fragile freshwater ecosystems. Besides, the impact of deteriorating quality of the freshwater ecosystems on the animal and human health is also discussed in detail. This book provides a comprehensive account of the techniques based on updated research in biotechnology, bio-remediation, phyto-remediation and nano-bioremediation. The role of biosorpers and biofilms as a remediation tool has also been detailed. The book is a ready reference for researchers, scientists and educators who are involved in the freshwater pollution, remediation and management studies. The book editors with an expertise in diverse research fields in freshwater ecosystems have congregated the most inclusive research accounts on the freshwater pollution and remediation and thus developed a repository of diverse knowledge on the subject.
    Type of Medium: Online Resource
    Pages: XV, 339 p. 49 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811382772
    URL: https://doi.org/10.1007/978-981-13-8277-2
    DOI: 10.1007/978-981-13-8277-2
    DDC: 363.73
    Language: English
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    Online Resource
    Agricultural Implications of Fukushima Nuclear Accident (IV) : After 10 Years (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pollution. ; Agriculture. ; Radiation dosimetry. ; Forestry. ; Physiology. ; Environmental monitoring. ; Pollution. ; Agriculture. ; Radiation Dosimetry and Protection . ; Forestry. ; Animal Physiology. ; Environmental Monitoring.
    Description / Table of Contents: 1. An Overview of our research -- 2. Recovery of Food Production from Radioactive Contamination Caused by the Fukushima Nuclear Accident -- 3. Annual Reduction of Transfer Factors of Radiocesium from Soil to Rice Cultivated in a KCl Fertilized and Straw Plowed-in Paddy Field from 2015 to 2021 -- 4. Effects of radiocesium from suspended matter and fallout on agricultural products -- 5. Verification of Uptake and Transport Properties of Cesium in Hydroponically Cultivated Quercus Serrata -- 6. Candidates for breeding target genes related to cesium transport in plants after the Fukushima Daiichi Nuclear Power Plant accident -- 7. Evaluation of the Absorption of Different Forms of Cesium from Soil -- 8. Structure, Composition, and Physicochemical Properties of Radiocesium-Bearing Microparticles Emitted by the Fukushima Daiichi Nuclear Power Plant Accident -- 9. Verification of Effects on Crops and Surrounding Environment in Agriculture Using Radioactively Contaminated Grass Silage Compost Made by Aerobic Ultra-High Temperature Fermentation -- 10. Transport of 137Cs into Fruits after External Deposition onto Japanese Persimmon Trees -- 11. Progress Towards Managing Radiocesium Contamination in Orchards -- 12. Overview of Radiocesium Dynamics in Forests: First Decade and Future Perspectives -- 13. Toward the Estimation of Radiocesium Activity Concentration in Trunks of Coppiced Quercus Serrata: Leaf Availability Instead of Felling -- 14. Decomposition of Organic Matters in a Forest Floor Enhanced Downward Migration of Radioactive Cs after the Accident of the FDNPP -- 15. Effect of exchangeable and non-exchangeable potassium in soil on cesium uptake by Quercus serrata seedlings -- 16. Ten-year Transition of Radiocesium Contamination in Wild Mushrooms in the University of Tokyo Forests after the Fukushima Accident -- 17. Challenge to resume production of mushroom bed logs by potassium fertilizer application -- 18. Studies on the revitalization of radioactive-contaminated mushroom log forests: focus on shoots -- 19. Contribution of cesium-bearing microparticles to cesium in soil and river water of the Takase River watershed and their effect on the distribution coefficient -- 20. Global Fallout: Radioactive Materials from Atmospheric Nuclear Tests That Fell Half a Century Ago and Where to Find Them -- 21. Resilience Education Program in Iitate Village for the Young Generation.
    Abstract: This open access book presents the findings from on-site research into radioactive cesium contamination in various agricultural systems affected by the Fukushima Daiichi Nuclear Power Plant accident in March 2011. This fourth volume in the series reports on studies undertaken at contaminated sites such as farmland and forests, focusing on soil, water, mountain, agricultural products, and animals. It also provides additional data collected in the subsequent years to show how the radioactivity levels in agricultural products and their growing environments have changed with time and the route by which radioactive materials entered agricultural products as well as their movement between different components (e.g., soil, water, and trees) within an environmental system (e.g., forests). The book covers various topics, including radioactivity testing of food products; decontamination trials for rice and livestock production; the state of contamination in, trees, mushrooms, and timber; the dynamics of radioactivity distribution in paddy fields and upland forests; damage incurred by the forestry and fishery industries; and the change in consumers’ attitudes. In the series of this book, a real-time radioisotope imaging system has been introduced, a pioneering technique to visualize the movement of cesium in soil and in plants. This is the only book to provide systematic data on the actual change of radioactivity, which is of great value to all researchers who wish to understand the effect of radioactive fallout on agriculture. In addition, it helps the general public better understand radio-contamination issues in the environment. The project is ongoing; the research groups from the Graduate School of Agricultural and Life Sciences of The University of Tokyo continue their work in the field further to evaluate the long-term effects of the Fukushima accident.
    Type of Medium: Online Resource
    Pages: XIII, 276 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811993619
    URL: https://doi.org/10.1007/978-981-19-9361-9
    DOI: 10.1007/978-981-19-9361-9
    DDC: 363.73
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  • 65
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    Water Resources Management of the People’s Republic of China : Framework, Reform and Implementation (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Pollution. ; Water. ; Hydrology. ; Environmental management. ; Energy policy. ; Energy and state. ; Pollution. ; Water. ; Environmental Management. ; Energy Policy, Economics and Management.
    Description / Table of Contents: Chapter 1. Physical settings and water challenges -- Chapter 2. Water resources management framework -- Chapter 3. Water resources management institutions -- Chapter 4. River basin management -- Chapter 5. Water resources allocation and regulation -- Chapter 6. Water rights system -- Chapter 7. Water pricing -- Chapter 8. Groundwater management -- Chapter 9 Water quality management -- Chapter 10. Recycled water use management -- Chapter 11. The strictest water resources management strategy and three redlines -- Chapter 12 River and lake leadership system -- Chapter 13. Water resources asset management -- Chapter 14. Water resources allocation and regulation in Yellow River basin -- Chapter 15. Agricultural water management in northern China -- Chapter 16 Integrated urban and rural water affair management reform: Shanghai and Beijing -- Chapter 17 -- Environmental flow definition and management: a case study of Jiaojiang River -- Chapter 18. Climate change and water resources -- Chapter 19 Conclusions and outlook.
    Abstract: This book explores water resources management issues in China and possible solutions. It analyzes a wide range of general and specific topics, providing case studies and a balanced review of the past and present situation as well as future developments. The book begins with a general introduction and an overview of hydrology, water resources, and development issues in China. It then presents a management framework, including a management system, management institutions, river basin management, water pricing, water rights, and groundwater management, and discusses its implementation, covering water resources allocation and regulation in the Yellow River, integrated water affair management reforms, and agricultural water management in northern China. The last section focuses on the current reforms and hot topics, with strong emphasis on stringent water resource strategies applied to the river and lake principle system, recycled water use and water resources asset management, as well as climate change impacts, and concludes with a summary of the many changes in the water sector in China and a look at the road ahead and the areas that still need to be reformed.
    Type of Medium: Online Resource
    Pages: XIX, 455 p. 42 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030619312
    Series Statement: Global Issues in Water Policy, 26
    URL: https://doi.org/10.1007/978-3-030-61931-2
    DOI: 10.1007/978-3-030-61931-2
    DDC: 363.73
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  • 66
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    Advanced Nano-Bio Technologies for Water and Soil Treatment (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pollution. ; Refuse and refuse disposal. ; Environmental chemistry. ; Pollution. ; Waste Management/Waste Technology. ; Environmental Chemistry.
    Description / Table of Contents: Preface -- Part I Reductive Technologies -- Geochemical Principles of Reductive Remediation Processes -- Nanoscale Zero-Valent Iron Particles for Water Treatment: from Basic Principles to Field-Scale Applications -- Other Chemical Reductive Methods -- Combination of Electrokinetics and nZVI Remediation -- Field Study I: In Situ Chemical Reduction Using Nanoscale Zero-valent Iron Materials to Degrade Chlorinated Hydrocarbons -- Field Study II: Pilot Application of nZVI/DC-combined Methods at Aargau Site -- Part II Oxidative Technologies -- Introduction to Oxidative Technologies for Water Treatment -- Ferrates as Powerful Oxidants in Water Treatment Technologies -- Radical Reactions and Their Application for Water Treatment -- Photo-oxidation Technologies for Advanced Water Treatment -- The Use of Nanomaterials in Electro-Fenton and Photoelectro-Fenton Processes -- Field Study III: Evidence Gained from Site Studies for the Performance of Ferrate(VI) in Water and Wastewater Treatment -- Field Study IV: Arsenic Removal from Groundwater by Ferrate with the Concurrent Disinfecting Effect—Semi-pilot on-site Application -- Field Study V: Combined Oxidation Technology using Ferrates (FeIV–VI) and Hydrogen Peroxide for Rapid and Effective Remediation of Contaminated Water—Comprehensive Practically Focused Study -- Part III Biotechnologies for Water Treatment -- Biotechnologies for Water Treatment -- Enzyme-Based Nanomaterials in Bioremediation -- Bioelectrochemical Processes for the Treatment of Oil-Contaminated Water and Sediments -- Field Study VI: The Effect of Loading Strategies on Removal Efficiencies of a Hybrid Constructed Wetland Treating mixed Domestic and Agro-Industrial Wastewaters -- Field Study VII: Field Study of Three Different Injectable Oxygen Sources to Enhance Mono-Aromatic Solvents in situ Biodegradation -- Field Study VIII: Nano-bioremediation: nZVI for Inorganic and Organic Contamination -- Part IV Biotechnologies for Soil Treatment -- Biotechnologies for Soil Treatment -- Mycoremediation of Contaminated Soils -- Composting Practices for the Remediation of Matrices Contaminated by Recalcitrant Organic Pollutants -- Modern Bioremediation Approaches: Use of Biosurfactants, Emulsifiers, Enzymes, Biopesticides, GMOs -- Field Study IX: Pilot-Scale Composting of PAH-Contaminated Materials—Two Different Approaches -- Field Study X: Oil Waste Processing Using Combination of Physical Pretreatment and Bioremediation -- Part V Ecotoxicology of Both Environmental Pollutants and Nanomaterials Used for Remediation -- Ecotoxicology of Environmental Pollutants -- Ecotoxicity of Nanomaterials Used for Remediation -- VI Future Prospects -- Future Prospects for Treating Contaminants of Emerging Concern in Water and Soils/Sediments -- Part VII Technical Chapters -- Tool I: Characterization of nZVI Mobility in 1D and Cascade Columns by Ferromagnetic Susceptibility Sensor -- Tool II: Membrane Interface Probe -- Tool III: Fracturing for Enhanced Delivery of In situ Remediation Substances in Contaminated Sediments -- Tool IV: Monitoring of nZVI Migration and Fate in the Groundwater Conditions -- Tool V: Microbiological Methods for Monitoring nZVI Performance in Groundwater Conditions.
    Abstract: This edited work presents a comprehensive treatise on the latest progress in the field of selected innovative nanotechnologies, biotechnologies, and their possible combinations for efficient elimination of a broad range of pollutants from various types of water and soil. It covers the underlying principles of all the key technologies (reductive and oxidative technologies for water treatment and biotechnologies for water and soil treatment). Moreover, it includes toxicological evaluation of emerging pollutants and novel engineered nanoparticles, as well as providing results of field-scale verification and application of the most promising technologies. Central aspects covered in this book include: geochemistry of iron, properties of iron nanoparticles (nZVI) and related materials for water treatment, in situ methods for groundwater treatment, evaluation of various combined nano/bio technologies, mechanisms and efficiencies of degradation/dechlorination of chlorinated hydrocarbons (as well as other organic pollutants like POPs, PAHs, etc.), elimination of arsenic and Cr(VI) from water, advanced oxidation processes with a strong focus on high-valent states of iron (ferrates), radical reactions, photooxidation, Fenton reactions, disinfection, and biodegradation including mycoremediation and composting of a wide range of pollutants from water and soil. In addition, technical details of selected strategies adopted for a pilot/full-scale application of key nano-/biotechnologies, i.e. nZVI injection into groundwater, field-scale contaminant monitoring, nanoparticle migration, and microbiological methods for monitoring nZVI performance in groundwater conditions, are presented. Therefore, this multidisciplinary book will be suitable for a broad readership including environmental scientists, practitioners, policymakers, toxicologists, and, of course, students of diverse fields such as materials science, chemistry, biology, geology, hydrogeology, engineering, etc.
    Type of Medium: Online Resource
    Pages: XXV, 657 p. 210 illus., 133 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030298401
    Series Statement: Applied Environmental Science and Engineering for a Sustainable Future,
    URL: https://doi.org/10.1007/978-3-030-29840-1
    DOI: 10.1007/978-3-030-29840-1
    DDC: 363.73
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    Bioenergy Research: Basic and Advanced Concepts (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pollution. ; Refuse and refuse disposal. ; Environmental engineering. ; Biotechnology. ; Bioremediation. ; Environmental chemistry. ; Pollution. ; Waste Management/Waste Technology. ; Environmental Engineering/Biotechnology. ; Environmental Chemistry.
    Description / Table of Contents: 1 Downstream Processing of Biofuels -- 2 Application of Micro-organisms for Biofuel Production -- 3 Influence of Significant Parameters on Cellulase Production by Solid State Fermentation -- 4 Influence of Xenobiotics on Fungal Ligninolytic Enzymes -- 5 Challenges in Bioethanol Production; Effect of Inhibitory Compounds -- 6 Engineering of Zymomonas Mobilis for enhanced Biofuel production -- 7 Sustainable Production of Hydrogen by Algae: Current Status and Future Perspectives -- 8 Bioprocess Parameters for Thermophilic and Mesophilic Biogas Production: Recent Trends and Challenges -- 9 Microbial and Bioinformatics Approach in Biofuel Production -- 10 Substrate Characterization in the Anaerobic Digestion Process. .
    Abstract: This volume is first part of the five-part set on bioenergy research. This volume covers current developments and both basic and advanced concepts in bioenergy production. Based on bioenergy road map, the book will also evaluate about the ratio existing between current challenges associated and practical implementation of these biofuels. The book complies up to-date progressive development in available bioenergy options and discusses opportunities and existing risks. The main objective of the book is to provide insights into the opportunities and required actions for the development of an economically viable bioenergy industry for practical replacement of fossil fuels. This book is of interest to teachers, researchers, scientists, capacity builders and policymakers. Also the book serves as additional reading material for undergraduate and graduate students of environmental sciences. National and international bioenergy scientists, policy makers will also find this to be a useful read. Other four volumes of this set explore latest developments, commercial opportunities, waste to energy and integrated solution for bioenergy concerns.
    Type of Medium: Online Resource
    Pages: XII, 342 p. 82 illus., 57 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789813346116
    Series Statement: Clean Energy Production Technologies,
    URL: https://doi.org/10.1007/978-981-33-4611-6
    DOI: 10.1007/978-981-33-4611-6
    DDC: 363.73
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  • 68
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    Water Pollution and Management Practices (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pollution. ; Refuse and refuse disposal. ; Environmental monitoring. ; Environmental management. ; Pollution. ; Waste Management/Waste Technology. ; Environmental Monitoring. ; Environmental Management.
    Description / Table of Contents: Chapter 1. Microbial Contamination of Drinking Water -- Chapter 2. Landscape Perspective to River Pollution: A Case Study of Bentong River, Malaysia -- Chapter 3. Existence of Antibiotics in Waste Water as a Pollution Indicator -- Chapter 4. Application of Artificial Intelligence in Predicting Groundwater Contaminants -- Chapter 5. Arsenic Contamination of Ground Water and its Mitigation Strategies -- Chapter 6. Wastewater Reuse in Peri-Urban Agriculture Ecosystem: Current Scenario, Consequences and Control Measures -- Chapter 7. Nitrogenous wastes and its efficient treatment in wastewater -- Chapter 8. Application of Waste Water In Irrigation and Its Regulation with Special reference to Agriculture Residues -- Chapter 9. Riparian Ecotones-An Important Derivative Of Managing The River Pollution -- Chapter 10. Ecosystem Responses to Pollution in the Ganga River: Key Issues to Address River Management -- Chapter 11. An Overview on Heavy metal Contamination of Water System and Sustainable Approach for Remediation -- Chapter 12. An Overview of Sustainability of Textile Wastewater Management In Textile Sectors -- Chapter 13. Role of Coagulation/ flocculation Technology for the Treatment of Dye Wastewater: Trend and Future Aspect.
    Abstract: Water pollution is a matter of concern for both developing and developed parts of the world. This book presents an overview on water pollution and its sustainable management. The book discusses the fundamental aspects of water pollution as well as advanced sustainable technologies for abating water pollution. It is a comprehensive collection of information related with water pollutants which are extremely harmful to man, other living organisms and to the ecosystems. It is all-inclusive coverage of technical, socio-political, scientific as well as social issues revolving around water pollution and management. The book brings out innovative ideas promoting sustainable technologies and extensively covers the diversity of modern technologies related to prevention of water pollution. Book also covers social aspects of water related issues. It is an essential reading for upper level graduates and undergraduates pursuing environmental studies and researchers in the field of waste water management.
    Type of Medium: Online Resource
    Pages: XVI, 331 p. 31 illus., 27 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811583582
    URL: https://doi.org/10.1007/978-981-15-8358-2
    DOI: 10.1007/978-981-15-8358-2
    DDC: 363.73
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    Climate Change and Water Resources in Africa : Perspectives and Solutions Towards an Imminent Water Crisis (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Pollution. ; Sustainability. ; Water. ; Hydrology. ; Climatology. ; Pollution. ; Sustainability. ; Water. ; Climate Sciences.
    Description / Table of Contents: Dedication -- Citations -- Foreword by Felix D. Dakora -- Foreword by Daniel Nyanganyura -- Preface -- Acknowledgement to Peer Reviewers -- Authors and Contributors -- About the Editors -- Chapter 1: Introduction: Water Resource Management within the Climate Change Context in Africa: Synthesis, Key Findings and Future Challenges -- Chapter 2: Africa-wide trends in development and water resources through a climate change lens -- Chapter 3: Water Resource Availability and Quality in the North Africa Region under Climate Change -- Chapter 4: Climate Change and Water Resources in West Africa: A Case Study of Ivory Coast, Benin, Burkina Faso and Senegal -- Chapter 5: Climate change impact on hydrological regimes and extreme events in southern Africa -- Chapter 6: Historic climatic variability and change: the importance of managing Holocene and Late Pleistocene groundwater in the Limpopo River Basin, southern Africa -- Chapter 7: A framework for IWRM in the Water-Energy-Food Nexus for the Senegal River Delta -- Chapter 8: Cumulative Impacts of Climate Change Variability around the Goronyo Dam in the Iullemmeden Basin, Northwest Nigeria -- Chapter 9: Lentic-Lotic Water System Response to Anthropogenic and Climatic Factors in Kenya and their Sustainable Management -- Chapter 10: Hydrology and climate impacts on streamflow and sediment yield in the Nyando River Basin, Kenya -- Chapter 11: Saharan agriculture in the Algerian oasis: limited adaptation to environmental, social and economic changes -- Chapter 12: Water management policy for freshwater security in the context of climate change in Senegal -- Chapter 13: Assessment of Hydrological Impacts of Climate Change on the Diarha Watershed -- Chapter 14: Water resources in the Sahel and adaptation of agriculture to climate change: Burkina Faso -- Chapter 15: Impacts of climate change on water resources in the Volta River Basin: reducing vulnerability and enhancing livelihoods and sustainable development -- Chapter 16: Potential Transboundary Impacts of the Grand Ethiopian Renaissance Dam under Climate Change and Variability -- Chapter 17: Strengthening flood and drought risk management tools for the Lake Chad basin -- Chapter 18: Developing a Framework for the Water-Energy-Food Nexus in South Africa -- Chapter 19:Mainstreaming Climate Change into Transboundary River Basins: a SADC Regional Case Study -- Chapter 20: Does the use of local knowledge in complex systems reduce vulnerability to climate change? Insights from nexus water management in the Niger basin -- Chapter 21: Proposed research, science, technology and innovation to address current and future challenges of climate change and water resource management in Africa -- Index. .
    Abstract: This book dedicated to “Climate Change and Water Resources in Africa” sets out the many challenges and implications of climatic change for freshwater resources in Africa, including its rivers, lakes and aquifers. Under the influence of a range of human factors, the status of water resources in Africa has been changing for decades, transpiring in changes in water flow and variability, falling groundwater levels, changes in rainfall levels and timing, as well as overall decreasing water quality. Indeed, change is not new in this context. Climate change, however, will strongly accelerate the rate of change, affecting the ability of people and societies to respond in a timely manner to address their own needs. With this in mind, this book has been dedicated to providing a deeper analysis of the effects of climate change on water resources in some of the most vulnerable areas in Africa, including the approaches that may help reduce or mitigate the impacts of climate change. In this regard, while there is no quick fix to the pressures imposed on water resources by climate change, it is clear that increasing the resilience of ecosystems and communities to extreme events such as flooding and drought, and integrating climate change risks and opportunities into development decision making, will be key. It is also important that wealthier countries as well as major current GHG-emitting countries assume responsibility for their historic GHG emissions and support those countries that are most impacted by those emissions to adapt to such impacts, while reducing their own carbon footprints. As a whole, this book intends to contribute to the debate around climate change in relation to water resources management in the African continent, and in particular inform policy decisions and actions that will improve governments’ and communities’ ability to manage the challenges of climate change and variability in relation to the aquatic ecosystems upon which they depend.
    Type of Medium: Online Resource
    Pages: XXX, 521 p. 214 illus., 193 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030612252
    URL: https://doi.org/10.1007/978-3-030-61225-2
    DOI: 10.1007/978-3-030-61225-2
    DDC: 363.73
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    Prospects of Fresh Market Wastes Management in Developing Countries (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pollution. ; Water. ; Hydrology. ; Refuse and refuse disposal. ; Green chemistry. ; Economic development. ; Pollution. ; Water. ; Waste Management/Waste Technology. ; Green Chemistry. ; Development Studies.
    Description / Table of Contents: 1. Characterization of fresh market wastewater and solid wastes -- 2. Fresh market wastes Management Practices and Their Impact on Human Health -- 3. Treatment Technologies of fresh market wastewater -- 4. Generation of Polycyclic Aromatic Hydrocarbons from Microalgae Biomass of fresh Market Wastewater Phycoremediation -- 5. Application of Natural Coagulants for fresh market wastewater Treatment -- 6. Anaerobic Digestion of fresh solid wastes -- 7. Electricity production from fresh solid wastes using microbial fuel cells -- 8. Remediation of xenobiotics in fresh market wastewater using nanotechnoogy -- 9. Biofilter Aquaponic system for nutrients removal from fresh market wastewater -- 10. Reduction of poultry slaughterhouse wastewater pollutants using sequencing batch reactors (SBR) enhanced by composite fibre for safe disposal.
    Abstract: This book focuses on the prospects of fresh market waste management in developing countries. It characterizes fresh market wastewater and solid wastes, and highlights the human health impact of corresponding waste management practices. With regard to treatment technologies, the book discusses the anaerobic digestion of fresh solid wastes; the application of natural coagulants for wastewater treatment; the remediation of xenobiotics in wastewater using nanotechnology; and biofilter aquaponic systems for nutrient removal. All of these technologies are recent innovations, offer several concrete advantages, and can be applied in developing countries as non-central treatment systems. In addition, the book covers electricity production from fresh solid wastes using microbial fuel cells, demonstrating the potential held by recycling fresh market wastewater and solid wastes.
    Type of Medium: Online Resource
    Pages: XI, 178 p. 33 illus., 18 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030426415
    Series Statement: Water Science and Technology Library, 92
    URL: https://doi.org/10.1007/978-3-030-42641-5
    DOI: 10.1007/978-3-030-42641-5
    DDC: 363.73
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    Paths to Clean Water Under Rapid Changing Environment in China (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pollution. ; Water. ; Hydrology. ; Environmental monitoring. ; Freshwater ecology. ; Marine ecology. ; Pollution. ; Water. ; Environmental Monitoring. ; Freshwater and Marine Ecology.
    Description / Table of Contents: Current situation of water pollution in China -- Challenges and opportunities to treat water pollution -- Facing water pollution under rapid changing environment: China’s experiences -- Conclusion.
    Abstract: This book mainly provides the current status of water pollution faced by China under rapid changing environment and the actions that have been taken for prevention and treatment of water pollution. It points out that the water pollution situation is severe. Facing water pollution, China’s experiences include several aspects on source control and pollution interception, internal nutrient removal of sediment, ecological restoration, and water transfer policy. There exists both the opportunity and challenge for the prevention and control of water pollution in China. The book contains numerous charts and diagrams which further illustrating China’s paths to clean water.
    Type of Medium: Online Resource
    Pages: VIII, 96 p. 29 illus., 19 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811900914
    Series Statement: SpringerBriefs in Water Science and Technology,
    URL: https://doi.org/10.1007/978-981-19-0091-4
    DOI: 10.1007/978-981-19-0091-4
    DDC: 363.73
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    Human Health Risk Assessment of Toxic Chemical Pollutants in Stormwater : Implications for Urban Stormwater Reuse (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pollution. ; Water. ; Hydrology. ; Environmental protection. ; Civil engineering. ; Pollution. ; Water. ; Soil and Water Protection.
    Description / Table of Contents: Background -- Research design -- Linking traffic and land use to stormwater quality -- Human health risk assessment from toxic chemical pollutants in stormwater -- Implications for stormwater management and recommendations for future research.
    Abstract: This book presents a detailed analysis in relation to human health risk assessment of the main toxic chemical pollutants in urban stormwater generated from urban traffic and land use activities. The knowledge presented in this book was derived based on comprehensive experimental investigations including field sampling, laboratory testing, mathematical modelling, spatial analysis and multivariate and univariate statistical data analyses. The key highlights of the book include the quantitative assessment of the human health risk posed by key toxic chemical pollutants in urban stormwater and the development of linkages between risk and traffic and land use. Additionally, a suite of mathematical equations are presented to predict human health risk based on traffic and land use characteristics through mathematical modelling. These outcomes can significantly assist in effective stormwater risk management under changing traffic and land use in the urban environment. The knowledge presented is of particular interest to readers such as stormwater treatment design specialists, decision-makers and urban planners since these outcomes provide practical suggestions and recommendations for effective urban stormwater treatment design.
    Type of Medium: Online Resource
    Pages: VIII, 86 p. 58 illus., 49 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811996160
    Series Statement: SpringerBriefs in Water Science and Technology,
    URL: https://doi.org/10.1007/978-981-19-9616-0
    DOI: 10.1007/978-981-19-9616-0
    DDC: 363.73
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    Assessing Environmental Risk of Oil Spills with ERA Acute : A New Methodology (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Pollution. ; Water. ; Hydrology. ; Environment. ; Environmental monitoring. ; Pollution. ; Water. ; Environmental Sciences. ; Environmental Monitoring.
    Description / Table of Contents: Preface -- Introduction to the concepts and use of Era Acute -- Environmental Risk Management Applications of Era Acute -- An Era Acute Model Overview -- Testing and Validating against Historic Spills -- Handling uncertainty and Sensitivity of Era Acute towards input Parameters -- Supplementary Information 1.
    Abstract: This open access book introduces readers to a new methodology for assessing the risks to the marine environment following accidental oil spills. The methodology will soon be implemented on the Norwegian Continental Shelf and will be complemented by guidelines for its use in a regulatory framework. The brief book is intended to provide international readers with a basic grasp of what the ERA Acute methodology consists of, what its applications are, and the underlying impact and restoration models used in its development. The content is divided into three main parts: an introduction and overview of risk management applications for generalists at the management level, a model overview for generalist scientists, and a more detailed final section for risk assessment professionals, which presents the results of the validation and sensitivity testing. .
    Type of Medium: Online Resource
    Pages: XVI, 119 p. 35 illus., 34 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030701765
    Series Statement: SpringerBriefs in Environmental Science,
    URL: https://doi.org/10.1007/978-3-030-70176-5
    DOI: 10.1007/978-3-030-70176-5
    DDC: 363.73
    Language: English
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    Online Resource
    Microfiber Pollution (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pollution. ; Building materials. ; Sustainability. ; Pollution. ; Wood, fabric, and textiles. ; Sustainability.
    Description / Table of Contents: Microfiber Pollution – A Sustainability Issue -- Microfiber Shedding of Textile Materials – Mechanism and Analysis Techniques -- Factors Influencing Microfiber Shedding – Role of Textile and Apparel Characteristics -- Domestic Laundry – A major cause of microfiber shedding -- Impact of microfiber/Microplastic pollution -- Microfiber Pollution Prevention - Mitigation Strategies and Challenges.
    Abstract: This book provides insights into microfiber pollution in textile industries that would help researchers and professionals to work from the textile point of view to mitigate the problem, and create a green sustainable future. Microplastic pollution has received great importance due to its adverse environmental and health impact. Microplastic particles are found to contaminate the ecosystem. Research has reported microplastics on seashores, in deep seas, freshwater systems including rivers and lakes, and most importantly in the air. Various land-based and water-based organisms are also contaminated with microplastics. The most serious issue is when these particles are found in the food chain and air which can reach the human system. It has been estimated that human beings can intake up to 1,21,000 microplastic particles in a year through food and inhalation. Being one of the most polluting industries, the contribution of Textile industries in microplastic pollution is extremely higher (around 35%). This book addresses the issue of microfiber/microplastic pollution cause by various techniques including home laundry and the ways to alleviate it.
    Type of Medium: Online Resource
    Pages: XV, 243 p. 53 illus., 48 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811941856
    Series Statement: Sustainable Textiles: Production, Processing, Manufacturing & Chemistry,
    URL: https://doi.org/10.1007/978-981-19-4185-6
    DOI: 10.1007/978-981-19-4185-6
    DDC: 363.73
    Language: English
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    The Secret Life of Chemicals (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Pollution. ; Environmental management. ; Refuse and refuse disposal. ; Environmental health. ; Chemicals Safety measures. ; Pollution. ; Environmental Management. ; Waste Management/Waste Technology. ; Environmental Health. ; Chemical Safety.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2: Pesticides in our food -- Chapter 3. The plastics revolution -- Chapter 4. Toxic metals -- Chapter 5. The Indestructibles -- Chapter 6. Air pollutants -- Chapter 7. Chemicals from paper manufacture and use -- Chapter 8. Chemical exposure in the workplace -- Chapter 9. Fluorocarbons -- Chapter 10: Radiation -- Chapter 11. How do our bodies deal with chemicals? -- Chapter 12: Genetic variability and the risk of disease – the advantages and disadvantages of being different -- Chapter 13. Environmental chemicals and our genes -- Chapter 14. Environmental chemicals and mitochondria -- Chapter 15. Environmental chemicals and our immune system -- Chapter 16: Just because the amounts are small, does it mean they are safe? -- Chapter 17. What can we do for a better future?.
    Abstract: This book provides extensive information on the chemicals that inhabit our environment, our food, our water and our air and the impact that they may be having on human health. The author is a medical scientist, with training in the law. The book documents current understanding about pesticides in food, the plastics revolution, toxic metals, air, water and electronic waste pollutants, chemical exposure in the workplace, radiation pollutants, chemical exposure and hearing loss, how our bodies deal with chemicals, genetic variability and the risk of disease, the effect of chemicals on genes, mitochondria and the immune system and what we can do about it all. Industrialisation has resulted in many thousands of chemicals, which are being continuously developed and often escaping from where they are used into our human environment, without us really knowing enough about them. In high dosages or with continuous small dosage, the evidence suggests, that many of them could interfere with human health and some of them are known to be doing so. But for the vast majority, we are left wondering whether some could be responsible for some diseases the causes of which are inadequately understood. Every chapter is thoroughly reinforced with several pages of references from the peer-reviewed literature.
    Type of Medium: Online Resource
    Pages: XV, 241 p. 1 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030803384
    URL: https://doi.org/10.1007/978-3-030-80338-4
    DOI: 10.1007/978-3-030-80338-4
    DDC: 363.73
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    Rapid Refrigeration and Water Protection : Next Generation Adsorbents (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Pollution. ; Water. ; Hydrology. ; Environment. ; Environmental chemistry. ; Chemistry, Technical. ; Nanotechnology. ; Pollution. ; Water. ; Environmental Sciences. ; Environmental Chemistry. ; Industrial Chemistry. ; Nanotechnology.
    Description / Table of Contents: Chapter 1 Introduction -- Chapter 2 Towards the Development of Compact and High Efficiency Adsorption Heat Pumps -- Chapter 3 Synthesis and Characterization of Various MOFs and MOFs-Zeolite Com-posites: Water Adsorption and Rapid Cooling Production -- Chapter 4 Specific Heat Capacity of Carbon-based Composites for Adsorption Heat Pump and Desalination Applications -- Chapter 5 Characterizing Adsorbent Materials Employing Atomic Force Microscopy -- Chapter 6 Advanced Adsorbents for Ecological Applications: Water Harvesting from the Atmosphere and Recuperation Heat and Moisture in Ventilation Systems -- Chapter 7 Thermochemical Conversion of Lignocellulosic Waste to Activated Carbon: A Potential Resource for Industrial Wastewater Treatment -- Chapter 8 Carbon Nanomaterial-based Adsorbents for Water Protection -- Chapter 9 Nanoparticles-based Adsorbents for Water Pollutants Removal.
    Abstract: This book provides a cross-disciplinary, multi-scale assessment of the development of adsorption-based refrigerants and super-adsorbent-based wastewater purification. The book covers two major aspects from the 21st century, including the development of an environmentally benign adsorption cooling system and the preparation of a super-adsorbent for water purification. Although work has been published on these topics, the authors present the latest findings and introduce some new perspectives. The book is written as a reference book with contributions from global field experts and will appeal to water engineers, chemists, environmentalists, physicists, material scientists, nano-technologists, and environmental technologists.
    Type of Medium: Online Resource
    Pages: VIII, 265 p. 111 illus., 94 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030938451
    Series Statement: Springer Water,
    URL: https://doi.org/10.1007/978-3-030-93845-1
    DOI: 10.1007/978-3-030-93845-1
    DDC: 363.73
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    Resilience of Large Water Management Infrastructure : Solutions from Modern Atmospheric Science (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pollution. ; Water. ; Hydrology. ; Atmospheric science. ; Civil engineering. ; Climatology. ; Sustainability. ; Pollution. ; Water. ; Atmospheric Science. ; Civil Engineering. ; Climate Sciences. ; Sustainability.
    Description / Table of Contents: Chapter 1. Resilience Of Large Water Management Infrastructure -- Chapter 2. Survey Of Water Managers For 21st Century Challenges -- Chapter 3. Current Approaches For Resilience Assessment -- Chapter 4. Application Of Numerical Atmospheric Models -- Chapter 5. Infrastructure-Relevant Storms Of The Last Century -- Chapter 6. Sensitivity Of Probable Maximum Precipitation (PMP) -- Chapter 7. A Recommended Paradigm Shift In The Approach To Risks To Large Water Infrastructure In The Coming Decades -- Chapter 8. Safety Design of Water Infrastructures In A Modern Era.
    Abstract: Infrastructure that manages our water resources (such as, dams and reservoirs, irrigation systems, channels, navigation waterways, water and wastewater treatment facilities, storm drainage systems, urban water distribution and sanitation systems), are critical to all sectors of an economy. Realizing the importance of water infrastructures, efforts have already begun on understanding the sustainability and resilience of such systems under changing conditions expected in the future. The goal of this collected work is to raise awareness among civil engineers of the various implications of landscape change and non-climate drivers on the resilience of water management infrastructure. It identifies the knowledge gaps and then provides effective and complementary approaches to assimilate knowledge discovery on local (mesoscale)-to-regional landscape drivers to improve practices on design, operations and preservation of large water infrastructure systems.
    Type of Medium: Online Resource
    Pages: XV, 124 p. 42 illus., 37 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030264321
    URL: https://doi.org/10.1007/978-3-030-26432-1
    DOI: 10.1007/978-3-030-26432-1
    DDC: 363.73
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    Measurement, Analysis and Remediation of Environmental Pollutants (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pollution. ; Environmental engineering. ; Biotechnology. ; Bioremediation. ; Environmental monitoring. ; Environmental chemistry. ; Pollution. ; Environmental Engineering/Biotechnology. ; Environmental Monitoring. ; Environmental Chemistry.
    Description / Table of Contents: Quantification of Airborne Particulate And Associated Toxic Heavy Metals in Urban Indoor Environment and Allied Health Effects -- In-Situ Measurements of Aerosols from the High-Altitude Location in the Central Himalayas -- Significant Annual Variation in Atmospheric Pollutants during Fireworks Festival, ‘Diwali’ in Capital City of India -- Organic Air Pollutants: Measurement, Properties & Control -- Emissions of Particle-Bound Metals from On-Road Vehicle Emission: An Assessment of Potential Health Risk -- Chemical Composition Analysis of Airborne Coarse Particles and Their Source Apportionment at Kanpur -- Analysis of the Aerosols Environment in an Urban Context and Their Impact On Regional Meteorology -- Calipso Retrieval of Smoke Aerosols Over Upper Indo-Gangetic Plain -- Spatio-Temporal Study of Optical and Microphysical Properties of Atmospheric Brown Clouds Over the Indo-Gangetic Plains -- Spatial Variation of Airborne Allergenic Fungal Spores in the Ambient Pm2.5 — A Study in Rajkot City, Western Part of India -- Bioaerosol Health Effects from Moleculer to Global Scales -- Measurement, Analysis and Remediation of Biological Pollutants in Water -- Fundamentals of Measurement, Analysis, and Treatment of Selenium in Water -- Bioleaching of Selected Metals from E-Waste using Pure and Mixed Cultures of Aspergillus Species -- Recent Advances In Micro-Extraction Based Analytical Approaches For Pesticides Analysis In Environmental Samples -- Degradation and Removal of Anticonvulsant Drugs Through Microorganisms: A Review -- Remediation Approaches for Hexavalent Chromium -- Mercury and Its Remediation -- Oxidative Potential of Particulate Matter: A Prospective Measure to Assess Pm Toxicity -- Monitoring and Processing of Data for Effective Wasteload Allocation Modeling: Indian Perspective -- Methane Emission from Municipal Solid Waste Landfills – Estimation and Control -- Low-Cost Adsorptive Removal Techniques for Pharmaceuticals and Personal Care Products -- Measurement, Analysis, and Remediation of Bisphenol-A from Environmental Matrices -- Removal of Chromium Ions from Aqueous Solution using Eco-Friendly Based Adsorbents.
    Abstract: This book discusses contamination of water, air, and soil media. The book covers health effects of such contamination and discusses remedial measures to improve the situation. Contributions by experts provide a comprehensive discussion on the latest developments in the detection and analysis of contaminants, enabling researchers to understand the evolution of these pollutants in real time and develop more accurate source apportionment of these pollutants. The contents of this book will be of interest to researchers, professionals, and policy makers alike.
    Type of Medium: Online Resource
    Pages: XVIII, 474 p. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811505409
    Series Statement: Energy, Environment, and Sustainability,
    URL: https://doi.org/10.1007/978-981-15-0540-9
    DOI: 10.1007/978-981-15-0540-9
    DDC: 363.73
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    Persistent Pollutants in Water and Advanced Treatment Technology (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pollution. ; Environmental protection. ; Civil engineering. ; Environmental engineering. ; Pollution. ; Soil and Water Protection. ; Environmental Civil Engineering.
    Description / Table of Contents: Impact of Persistent Pollutants on Water Quality -- Marine microplastics: abundance, ecotoxic consequences of associated anthropogenic contaminants and interactions with microorganisms -- World profile of foreseeable strategies for the removal of per- and polyfluoroalkyl substances (PFASs) from water -- Plasticizers, plastic monomers, and their transformation products in environmental waters and wastewater -- Occurrence and Removal of phthalates from aqueous medium using bismuth tungstate-based photocatalysts -- Application of electrochemical technologies for the efficacious removal of persistent organic pollutants from wastewater -- Recent progress in Electrochemical/Electro-oxidation technology: its applicability in highly efficient treatment of persistent organic pollutants specially from coal processed wastewater.
    Abstract: This contributed volume discusses the current status of the occurrences, fate and transport of persistent pollutants in water and wastewater. This contents compile the state-of-the-art of emerging technologies such as nanotechnology, advanced oxidation process, membrane processes, sorption, etc. for the clean-up of persistent pollutants in water including heavy metals, pharmaceuticals, phenolic compounds as well as microplastics and their by-products. This volume will be useful as a guide for the researchers to build strategies to deal with persistent pollutant. It also discusses the principal aspects of degradation mechanism of the pollutants, toxic by-products and effectiveness of the emerging technologies. This volume will be a useful guide for those working in soil and water protection, and environmental civil engineering. .
    Type of Medium: Online Resource
    Pages: XVII, 477 p. 136 illus., 95 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819920624
    Series Statement: Energy, Environment, and Sustainability,
    URL: https://doi.org/10.1007/978-981-99-2062-4
    DOI: 10.1007/978-981-99-2062-4
    DDC: 363.73
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    Water Resources Management in Romania (2020)
    Cham :Springer International Publishing :
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    Keywords: Pollution. ; Water. ; Hydrology. ; Physical geography. ; Pollution. ; Water. ; Physical Geography.
    Description / Table of Contents: Introduction -- Management of Surface Water Resources In Romania -- The Vulnerability of Water Resources From Eastern Romania to Anthropic Impact and Climate Changes -- Romanian Danube River Floodplain Functionality Assessment -- Romanian Upper Tisa Watershed, Between Water Resources and Hydrological Hazards -- Causes and Effects of Water Pollution in Romania -- Assessment of Some Diurnal Streamwater Profiles in Western and Northern Romania in Relation to Meteorological Data -- Water Resources Management in Razim-Sinoie Lakes Ecosystems -- Particularities of Drain Liquid in the Small Wetland of Braila Natural Park, Romania -- Water Supply Challenges and Achievements in Constanta County -- Drinking Water Supply Systems - Evolution towards Efficiency -- Water Resources Management in Siret Catchment -- Particular Hydrological Manifestations on the Lower Danube in the Current Climate -- Hydrological Impacts of Climate Changes in Romania and Adaptation Strategies -- Implementation of EU Water Framework Directive (2000/60/CE) in Romania - European Qualitative Requirements -- Drought and Insolvency: Case study of the Producer-Buyer Conflict (Romania, the period between the year 2011-2012) -- Conclusions and Recomendations. .
    Abstract: This book discusses water resources management in Romania from a hydrological perspective, presenting the latest research developments and state-of-the-art knowledge that can be applied to efficiently solve a variety of problems in integrated water resources management. It focuses on a wide range of water resources issues – from hydrology and water quantity, quality and supply to flood protection, hydrological hazards and ecosystems, and includes case studies from various watersheds in Romania. As such, the book appeals to researchers, practitioners and graduates as well as to anybody interested in water resources management.
    Type of Medium: Online Resource
    Pages: XII, 591 p. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030223205
    Series Statement: Springer Water,
    URL: https://doi.org/10.1007/978-3-030-22320-5
    DOI: 10.1007/978-3-030-22320-5
    DDC: 363.73
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    Arsenic in Drinking Water and Food (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pollution. ; Refuse and refuse disposal. ; Sustainability. ; Food science. ; Nutrition   . ; Pollution. ; Waste Management/Waste Technology. ; Sustainability. ; Food Science. ; Nutrition.
    Abstract: Arsenic contamination poses a major environmental problem, especially in Southeast Asian countries like Bangladesh and India. Threatening the health of millions of people due to arsenic’s toxicity and carcinogenicity, the major routes of arsenic exposure for humans are either through drinking water or crops. Rice is the crop most affected by arsenic owing to its cultivation in major arsenic contaminated areas, biogeochemical factors in the soil during rice growth, and specific features of rice that enable it take up more arsenic than other crop plants. This book addresses the problem of arsenic by pursuing a holistic approach. It presents the status quo in different parts of the world (North and South America, Europe, Asia, etc.) and provides essential information on food-related arsenic exposure risks for humans, and possible preventive and curative measures for tackling arsenic poisoning. It covers the arsenic contamination status of rice, rice-based products, other vegetables, fishes, mushrooms, and other foods, with a special focus on rice-arsenic interactions. The mechanisms of arsenic uptake, translocation and distribution in plants and grains are also explained. In closing, the book reviews a variety of prospective agronomic and biotechnological solutions to the problem of arsenic accumulation in rice grains. The book is intended for a broad audience including researchers, scientists, and readers with diverse backgrounds including agriculture, environmental science, food science, environmental management, and human health. It can also be used as an important reference guide for undergraduate and graduate students, university faculties, and environmentalists.
    Type of Medium: Online Resource
    Pages: XIII, 460 p. 44 illus., 24 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811385872
    URL: https://doi.org/10.1007/978-981-13-8587-2
    DOI: 10.1007/978-981-13-8587-2
    DDC: 363.73
    Language: English
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    Microplastic Pollution (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pollution. ; Environmental management. ; Sustainability. ; Pollution. ; Environmental Management. ; Sustainability.
    Description / Table of Contents: Effect Of Textile Parameters On Microfiber Shedding Properties Of Textiles -- Current State Of Microplastics Research In Saarc Countries – A Review -- Distribution And Impact Of Microplastics In The Aquatic Systems: A Review Of Ecotoxicological Effects On Biota -- Microplastics Pollution In Marine Environment: Occurrence, Fate And Effects (With A Specific Focus On Biogeochemical Carbon And Nitrogen Cycles -- Domestic Laundry And Microfiber Shedding Of Synthetic Textiles -- Microplastics In Dentistry- A Review.
    Abstract: This book addresses the emergent need to act on reducing or getting rid of micro plastic pollution, to achieve a sustainable environment. Microplastics are small plastic pieces, which are less than five millimeters long which can be harmful to our oceans and aquatic life. These predominantly include microfibers from clothing, microbeads, and plastic pellets. Microplastics impact aquatic creatures, turtles and birds. According to the first study on estimation of human ingestion of microplastic, on average a person consumes at least 50,000 particles of microplastic a year and breathes a similar quantity. Ingested microplastic particles can physically damage organs and also compromise immune function and stymie growth and reproduction. This book presents six informative chapters in order to alleviate the above mentioned issues .
    Type of Medium: Online Resource
    Pages: IX, 174 p. 28 illus., 25 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811602979
    Series Statement: Sustainable Textiles: Production, Processing, Manufacturing & Chemistry,
    URL: https://doi.org/10.1007/978-981-16-0297-9
    DOI: 10.1007/978-981-16-0297-9
    DDC: 363.73
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    Environmental Nanotechnology Volume 3 (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pollution. ; Nanotechnology. ; Agriculture. ; Environmental chemistry. ; Pollution. ; Nanotechnology. ; Agriculture. ; Environmental Chemistry.
    Description / Table of Contents: Preface -- 1. Nanotechnology in wastewater and the capacity of nanotechnology for sustainability (Oluranti Agboola) -- 2. Therapeutic use of inorganic nanomaterials in malignant diseases (Andreea-Roxana Lupu) -- 3. Modification of Oligomers and Reinforced Polymeric Composites by Carbon Nanotubes and Ultrasonic (Aleksandr Evhenovych Kolosov) -- 4. Understanding interactions of nanomaterials with soil: Issues and Challenges ahead (Arun Kumar) -- 5. Nanotechnology for Water Treatment (Rashid Ahmad) -- 6. Overview of Nanomaterial-Assisted Technologies for Denitrification Processes (Samad Sabbaghi) -- 7. Nanoencapsulation of Food Carotenoids (Lohith Kumar DH) -- 8. Nanomaterials in Agricultural Research: An Overview (Devendra K Payasi) -- 9. Understanding effect of the interaction of nanoparticles with roots on the uptake in plants (Arun Kumar) -- 10. Semiconductor Nanomaterials for Gas Sensor Applications (Marwa Farouk Elkady).
    Abstract: This third volume on environmental nanotechnology includes chapters dealing with topics such nanoremediation, waste water purification, nanosensors, nanomedicine, and nanofiltration. It also highlights the safety aspects and risk assessment and management related to several toxins, as well as nanotechnology related solutions for these challenges. The book also discusses new nanomaterials from the nexus of environment, water, remediation and total environment. .
    Type of Medium: Online Resource
    Pages: XV, 362 p. 60 illus., 44 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030266721
    Series Statement: Environmental Chemistry for a Sustainable World, 27
    URL: https://doi.org/10.1007/978-3-030-26672-1
    DOI: 10.1007/978-3-030-26672-1
    DDC: 363.73
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    Bioremediation of Industrial Waste for Environmental Safety : Volume II: Biological Agents and Methods for Industrial Waste Management (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pollution. ; Refuse and refuse disposal. ; Environmental management. ; Sustainability. ; Microbiology. ; Pollution. ; Waste Management/Waste Technology. ; Environmental Management. ; Sustainability. ; Microbiology.
    Description / Table of Contents: - Genetically Modified Organisms (GMOs) and Their Potential in Environmental Management: Constraints, Prospects and Challenges -- Advances in Bioremediation of Toxic Heavy Metals and Radionuclides in Contaminated Soil and Aquatic Systems. - Phycoremediation: Algae as Eco-Friendly Tools for the Removal of Heavy Metals from Wastewaters -- Phytoremediation: An Emerging Green Technology for Environmental Decontamination, Prospects for Future Research and Challenges -- Emerging and Ecofriendly Technologies for Removal of Organic and Inorganic Pollutants from Industrial Wastewaters -- Constructed Wetlands: A Clean-Green Technology for Degradation and Detoxification of Industrial Wastewaters -- Nano-Bioremediation: An Innovative Remediation Technology for Treatment and Management of Contaminated Sites -- Electro-Bioremediation: An Advanced Remediation Technology for Treatment and Management of Contaminated Soil -- Microbial Fuel Cell (MFC): An Innovative Technology for Wastewater Treatment and Power Generation -- Functional Diversity of Plant Endophytes and their Role in Assisted Phytoremediation -- Toxic Metals in Industrial Wastewaters and Phytoremediation Using Aquatic Macrophytes for Environmental Pollution Control: An Eco-Remedial Approach -- Microalgae: An Ecofriendly Tools for the Treatment of Wastewaters for Environmental Safety -- Phycoremediation: An Integrated and Eco-Friendly Approach for Wastewater Treatment and Value-Added Product Potential -- Pulp Paper Mill Wastewater: Eco-Toxicological Effects and Bioremediation Approaches for Environmental Safety. - Cadmium as Environmental Pollutant: Eco-Toxicological Effects, Health Hazards and Bioremediation Approaches for Its Detoxification from Contaminated Sites. - Cyanobacteria: The Eco-friendly Tools for the Treatment of Industrial Wastewaters. - Plant-Microbe Interactions for Bioremediation and Phytoremediation of Environmental Pollutants and Agro-Ecosystem Development -- Molecular Technologies for Assessment of Bioremediation and Characterization of Microbial Communities at Contaminated Sites. - Biochar: A Sustainable Tool in Soil Pollutants Bioremediation -- Bioremediation of Melanoidins Containing Distillery Waste for Environmental Safety -- Progresses in Bioremediation Technologies for Industrial Waste Treatment and Management: Challenges and Future Prospects.
    Abstract: Achieving environmental sustainability with rapid industrialization is currently a major global challenge. Industries are the key economic drivers, but are also the main polluters as untreated/partially treated effluents from industry are usually discharged into the aquatic environment or dumped. Industrial effluents often contain highly toxic and hazardous pollutants, which cause ecological damage and present and health hazards to living beings. As such, there is a pressing need to find ecofriendly solutions to deal with industrial waste, and to develop sustainable methods for treating/detoxifying waste before it’s released into the environment. As a low cost and eco-friendly clean technology, bioremediation can offer a sustainable alternative to conventional remediation technologies for the treatment and management of industrial wastes. This book (Volume II) describes the role of biological agents in the degradation and detoxification of organic and inorganic pollutants in industrial wastes, and presents recent bioremediation approaches for waste treatment and management, such as constructed wetlands, electro- bioremediation and nano-bioremediation, as well as microbial fuel cells. It appeals to students, researchers, scientists, industry professionals and experts in the field of microbiology, biotechnology, environmental sciences, eco-toxicology, environmental remediation and waste management and other relevant areas who are interested in biodegradation and bioremediation of industrial wastes for environmental safety.
    Type of Medium: Online Resource
    Pages: XXVIII, 538 p. 70 illus., 62 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811334269
    URL: https://doi.org/10.1007/978-981-13-3426-9
    DOI: 10.1007/978-981-13-3426-9
    DDC: 363.73
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    Environmental Processes and Management : Tools and Practices (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pollution. ; Water. ; Hydrology. ; Environmental management. ; Environmental sciences Mathematics. ; Environment. ; Pollution. ; Water. ; Environmental Management. ; Mathematical Applications in Environmental Science. ; Environmental Sciences.
    Description / Table of Contents: 1. HYDRO peaking in nordic rivers/ hydropeaking combined analysis of climate change and energy market -- 2. Annual Variability of Per Capita Renewable Water Resources: Long Term Water Planning Using SWAT Model in the Athi Catchment, Kenya -- 3. Monte Carlo simulation and fuzzy modelling of river water quality for multiple reaches using QUAL2Kw -- 4. Design of Stable Channel Using HEC-RAS: A Case Study of Tapi River, Surat City -- 5. Nutrient fluxes from agriculture: reducing environmental impact through optimum application -- 6. Air Quality Monitoring with Special Reference to Respirable Suspended Particulate Matter in an Industrial Area -- 7. The water-energy nexus prespective of hydropower in the context of climate Change -- 8. Biological methodologies for treatment of textile wastewater -- 9. Role of microbes in Environmental Biotechnology and its role in the environment -- 10. Environmental Hazards of Limestone Mining and Review of Adaptive Practices for Environment Management Planning -- 11. Water Optimisation in Thermal Power Plants -- 12. Geoengineering Structures of Crabs and Their Role in Nutrient Cycling in Mangrove Ecosystem of Mahanadi Delta of Odisha, India -- 13. Design Considerations of Sustainable Pervious Concrete Block Pavement -- 14. Analysis of Historical Records of Climate Change and the Calamitous Events in Kasmir Valley -- 15. Possible Remediation of Perils of Water Eminence and Extent -- 16. Optimization methodologies in complex water supply systems for energy saving and a correct management under uncertainty -- 17. Application of a low-cost technology to treat domestic sewage and to improve fertility of a barren lateritic soil -- 18. Parametric evaluation of water quality characteristics varying downstream from Shimla to Solan in Himachal Pradesh region, India -- 19. Partial replacement of fine aggregates with defluoridation sludge in cement mortars manufacturing: A critical review -- 20. Genetically Modified Crops and its impact on Environment -- 21. Degradation of Gemfibrozil (lipid regulating drug) by using Advanced Oxidation and Biological Processes: A Review -- 22. Source Apportionment of particulate matter - A Critical Review for Indian Scenario -- 23. A review on Ionic liquids as novel adsorbents for SO2 removal -- 24. Garden-Landscape Practices in Mughal Kashmir: Design, Planning and Management -- 25. Long Term Performance Evaluation of Permeable Reactive Barrier for Groundwater Remediation using Visual MODFLOW -- 26. Use of Electrical Resistivity Tomography for Detection and Delineation of Groundwater Contamination near a Non-engineered Solid Waste Landfill -- 27. Saltwater intrusion in coastal aquifers: A case of environmental management -- 28. Assessment of groundwater quality around Coal mining regions of Korba district, Chhattisgarh, Central India -- 29. Numerical errors associated with groundwater models and improving the reliability of models in environmental management issues -- 30. Staus of Groundwater Salinity in North West Region of India.-31. Irrigation Water Management under Changing Climate -- 32. Particle Swarm Optimization for identification of unknown groundwater pollution source -- 33. Fluoride Contamination and Abatement Measures: A Geoenvironmental Perspective -- 34. Interaction between Groundwater and surface water and its effect on groundwater quality -- 35. Assessment of an Intrinsic and a Specific vulnerability to identify Groundwater vulnerable zones of Nagpur city, India -- 36. Sustainable water management solutions -- Conclusions .
    Abstract: This book presents an in-depth, science-based approach to applying key project-management and spatial tools and practices in environmental projects. Providing important data for those considering projects that balance social-economic growth against minimizing its ill-effects on planet Earth, the book discusses various aspects of environmental engineering, as well as formula and analytical approaches required for more informed decision-making. Beginning with a broad overview of the factors and features of environmental processes and management, the book then clearly details the general application of fundamental processes, the characteristics of the different systems in which they occur, and the way in which these factors influence process dynamics, environmental systems, and their possible remedies. While primarily intended for professionals responsible for the management of environmental projects or interested in improving the overall efficiency of such projects, it is also useful for managers in the private, public, and not-for-profit sectors. Further, it is a valuable resource for students at both undergraduate and postgraduate levels, and an indispensable guide for anyone wanting to develop their skills in modern environmental management and related techniques.
    Type of Medium: Online Resource
    Pages: XXIV, 445 p. 105 illus., 71 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030381523
    Series Statement: Water Science and Technology Library, 91
    URL: https://doi.org/10.1007/978-3-030-38152-3
    DOI: 10.1007/978-3-030-38152-3
    DDC: 363.73
    Language: English
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  • 86
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    Online Resource
    Behavior of Radionuclides in the Environment I : Function of Particles in Aquatic System (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pollution. ; Radiation dosimetry. ; Environmental management. ; Environmental monitoring. ; Nuclear chemistry. ; Pollution. ; Radiation Dosimetry and Protection . ; Environmental Management. ; Environmental Monitoring. ; Nuclear Chemistry.
    Description / Table of Contents: 1 Microbial ecological function in migration of radionuclides in groundwater -- 2 Microbial diversity and possible activity in nitrate- and radionuclide-contaminated groundwater -- 3 Function of microbes on chemical species transformation of radionuclides -- 4 Direct detection of denitrifying bacteria in groundwater by GeneFISH -- 5 Difference in the solid-water distributions of radiocesium in rivers in Fukushima and Chernobyl -- 6 Function of colloidal and nanoparticles in sorption of radionuclides -- 7 Application of electron microscopy to understanding colloid-facilitated transport of radionuclides at the Mayak Production Association facility, near Lake Karachai, Russia -- 8 Numerical analysis of migration of nitrate ions in the groundwater system of Lake Karachai Area, Southern Ural, Russia -- 9 Commentary on the function of micro- to nano-scale particles in radionuclide migration through groundwater.
    Abstract: The 3-volume set highlights the behavior of radionuclides in the environment and focusing on the development of related fields of study, including microbiology and nanoscience. In this context, it discusses the behavior of radionuclides released in areas of Lake Karachai in Ural, and those released as a result of Chernobyl accident (1986), and in Fukushima (2011). Volume I presents the experiences gained in South Urals (“Mayak” plant, Lake Karachai), providing a scientific basis for more precise understanding of the behavior of radionuclides in complex subsurface environments. On the basis of monitoring data, it examines the pathways of radionuclide migration and the influence of the geological environment and groundwater on the migration, with a particular focus on particles from the nanoscale to microscale. It also discusses the function of microbes and microscale particles, from their direct interaction with radionuclides to their ecological role in changing the physic-chemical condition of a given environment. Lastly, the protective properties of geological media are also characterized, and mathematical modeling of contaminant migration in the area of Lake Karachai is used to provide information regarding the migration of radionuclides.
    Type of Medium: Online Resource
    Pages: X, 225 p. 93 illus., 63 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811506796
    URL: https://doi.org/10.1007/978-981-15-0679-6
    DOI: 10.1007/978-981-15-0679-6
    DDC: 363.73
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  • 87
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    Management of Irrigation and Water Supply Under Climatic Extremes : Empirical Analysis and Policy Lessons from India (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Pollution. ; Water. ; Hydrology. ; Environment. ; Climatology. ; Environmental management. ; Natural disasters. ; Pollution. ; Water. ; Environmental Sciences. ; Climate Sciences. ; Environmental Management. ; Natural Hazards.
    Description / Table of Contents: Chapter 1. Climate Risks for Irrigation, Water Supply and Sanitation in India: Overview and Synthesis -- Chapter 2. Climate Variability and Its Implications for Water Management in India -- Chapter 3. Water Management Challenges of Climate Extremes: A Case Study of Adaptive Strategies and Management Options -- Chapter 4. Managing Climate-Induced Water Risks: A Case Study of Institutional Alternatives -- Chapter 5. Planning for Water Resources Management under Climatic Extremes: The Case Study of a Hyper-arid Region -- Chapter 6. Planning of Rural Water Supply Systems: Role of Climatic Factors and Other Considerations -- Chapter 7. A Framework for Assessing Climate-induced Risk for Water Supply, Sanitation and Hygiene -- Chapter 8. Mapping Climate-Induced Risk for Water Supply, Sanitation and Hygiene in Maharashtra -- Chapter 9. Predictions of Disease Spikes induced by Climate Variability: A Pilot Real Time Forecasting Model Project from Maharashtra, India -- Chapter 10. Mapping Climate-Induced Risk for Water Supply, Sanitation and Hygiene in Rajasthan -- Chapter 11. Action Plans for Building Climate-Resilient Water Supply and Sanitation Systems: Results from Case Studies -- Chapter 12. Managing Climate-Induced Water Stress across the Agro-ecological Regions of India: Options and Strategies. Chapter 13. Conclusions and Areas for Future Research.
    Abstract: This volume provides a theoretical basis for the argument that available research that analyzes the impacts of climate on hydrology, water resources, and water systems, without factoring in the effect of climate variability, are inadequate and often misleading. Also, the book empirically shows that the impacts of climate variability on hydrology and water resources, and irrigation, water supply & sanitation systems are far more pronounced than the likely impacts of future change in climate. The book discusses technological, institutional and policy alternatives for reducing these impacts on various competitive use sectors, especially, irrigation, and water supply and sanitation through case studies of river basins in different hydrological setting. To set the context, the volume first presents the long term trends in precipitation and temperature in different regions of India, and compares them against inter-annual, inter-seasonal and intra-day variations in climatic parameters, to show how their differential impacts on water resources.
    Type of Medium: Online Resource
    Pages: XXV, 371 p. 99 illus., 80 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030594596
    Series Statement: Global Issues in Water Policy, 25
    URL: https://doi.org/10.1007/978-3-030-59459-6
    DOI: 10.1007/978-3-030-59459-6
    DDC: 363.73
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  • 88
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    Remediation of Chromium-Contaminated Soil: ​Theory and Practice​ (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pollution. ; Environmental chemistry. ; Environmental monitoring. ; Pollution. ; Environmental Chemistry. ; Environmental Monitoring.
    Description / Table of Contents: Contamination characteristics of soils and biological and chemical behavior of chromium in soil.-Mechanisms of Cr(VI) reduction by microorganisms -- Microbial remediation of chromium-contaminated soil -- Mechanism of chemical reduction of Cr(VI) -- Chemical remediation of chromium-contaminated soil -- Case of chrome-contaminated site remediation project.
    Abstract: In accordance with the global needs of heavy metal-contaminated site remediation, this book systematically introduces the latest theories and technical achievements of microbial and chemical treatment for the chromium pollution in the chromium slag and chromium-contaminated soil, combined with the author's research achievements over the decades. The book focuses on the biological and chemical behavior of chromium in soil, microbial, and chemical remediation for the chromium-contaminated soil and the cases of chromium-contaminated site remediation project. This book is used by the scientific researchers and engineering technicians engaged in chromium chemical industry and environmental protection. It is also used as a textbook and reference book for graduate students in environmental science and engineering, soil science, chemistry and chemical engineering, and other related fields.
    Type of Medium: Online Resource
    Pages: XI, 303 p. 190 illus., 142 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819954636
    Series Statement: Environmental Science and Engineering,
    URL: https://doi.org/10.1007/978-981-99-5463-6
    DOI: 10.1007/978-981-99-5463-6
    DDC: 363.73
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  • 89
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    Online Resource
    Atlas of Fallen Dust in Kuwait (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Pollution. ; Environmental geography. ; Atmospheric science. ; Analytical chemistry. ; Climatology. ; Pollution. ; Integrated Geography. ; Atmospheric Science. ; Analytical Chemistry. ; Climate Sciences.
    Description / Table of Contents: Dust storm Satellite images -- Deposited dust -- Dust particles size and statistical parameters -- Mineralogy (XRD) -- Inductively coupled plasma(ICP) -- Deposited rates of radionuclides -- Pollen in dust -- Other properties -- Spectro absorption.
    Abstract: This open access book serves as an atlas of deposited dust and dust storms in Kuwait in relation to local and global regions. It features a wealth of maps and images of dust storm trajectories in the region, together with detailed descriptions of the chemical and physical properties of fallen dust, including the amount, particle size, statistical parameters, spectra absorption, dust mineralogy, trace and major elements, organic matter, associated pollen, and radionuclides and connected pollutants. Given its scope, the book is a valuable resource for a broad range of researchers, including geologists, chemists, environmentalists, botanists, air quality specialists, nanotechnology scientists, and solar energy experts.
    Type of Medium: Online Resource
    Pages: XI, 250 p. 272 illus., 267 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030669775
    URL: https://doi.org/10.1007/978-3-030-66977-5
    DOI: 10.1007/978-3-030-66977-5
    DDC: 363.73
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  • 90
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    Organic Pollutants : Toxicity and Solutions (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Pollution. ; Toxicology. ; Refuse and refuse disposal. ; Biotechnology. ; Pollution. ; Toxicology. ; Waste Management/Waste Technology. ; Biotechnology.
    Description / Table of Contents: Chapter 1 -- Organic pollutants: Past, present and the future. Chapter 2 -- Persistent Organic Pollutants (POPs): Sources and adverse effects to human health and Environment. Chapter 3 -- Assessment of POPs in water. Chapter 4 -- Monitoring of POPs: A Global Perspective. Chapter 5 -- Organochlorines and organophosphates: Bioaccumulation and Toxicity. Chapter 6 -- Pharmaceutical pollutants in water: Toxicity and health hazards. Chapter 7 -- Textile organic chemicals in water: Pervasive toxicity to humans and aquatic animals. Chapter 8 -- Organic toxins in cosmetic products: Quantification and risk evaluation. Chapter 9 -- Disinfectant products: toxicity and health hazards. Chapter 10 -- Obesogens and obesity: Challenges and prospects. Chapter 11 -- Pheromones: A Potential alternative to organic recalcitrant compounds. Chapter 12 -- Microplastics as carriers of organic pollutants: An overview. Chapter 13 -- Removal of POPs through degradation mechanisms by possible technologies. Chapter 14 -- Microbes assisted adsorptive removal of melanoidin from distillery effluents. Chapter 15 -- Remediation of dye effluents using algal species. Chapter 16 -- Recovery of organic nutrients through the remediation of solid waste. Chapter 17 -- Post -- consumer organic waste management and nutrients recovery through ecofriendly techniques. Chapter 18 -- Instrumental applications in the analysis of various organic pollutants.
    Abstract: This volume describes the identification of emerging organic pollutants, mainly from industrial sources, their associated toxicological threats, and the latest green methods and biotechnological solutions to abate harmful impacts on people and the environment. The chapters present reviews on current applied toxicology research, occupational health hazards and green remedial solutions for pollution control in terrestrial and aquatic environments, with the aim of raising public awareness of these issues and providing chemists, toxicologists and environmental scientists with the knowledge to combat organic pollutants through sustainable means. Readers will learn about the multi-dimensional applications of materials and processes which harvest energy out of environmental remediation technologies, as well as the roles of biotechnology and nanotechnology in addressing high pollutant load. Specific attention is paid to technologies that draw energy through wastewater remediation, as this covers the primary means by which organic pollutants are introduced into the environment from industry and other sources. The book will be of use to pollution control boards, industry regulators, and students and researchers in the fields of biotechnology, biomedical science, hydrology and water chemistry.
    Type of Medium: Online Resource
    Pages: XVI, 600 p. 139 illus., 1 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030724412
    Series Statement: Emerging Contaminants and Associated Treatment Technologies,
    URL: https://doi.org/10.1007/978-3-030-72441-2
    DOI: 10.1007/978-3-030-72441-2
    DDC: 363.73
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  • 91
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    Water Governance and Management in India : Issues and Perspectives, Volume 2 (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pollution. ; Water. ; Hydrology. ; Sustainability. ; Climatology. ; Environmental management. ; Pollution. ; Water. ; Sustainability. ; Climate Sciences. ; Environmental Management.
    Description / Table of Contents: Introduction -- Catalysing groundwater governance -- Sustainable urban water management strategies -- Estimating efficiency of public investments in irrigation -- Tackling water quality issues -- Wetlands and water management: Finding common ground -- Data usage for development, management of water resources -- Whither federal governance for India’s long-term water security?
    Abstract: This book, the second volume in the series, continues to raise contextual issues and presents perspectives regarding multifaceted challenges in management and governance of water in India. This volume attempts to broad base and expand the dialogue started in the first volume and would touch upon issues that need immediate discussion but have been left unattended like politics and management of groundwater, efficient utilization of water in agriculture (irrigation) and improving water use efficiency and building resilience. As in the first volume, this book presents a set of suggestions and recommendations in each chapter that can help frame policy guidelines in the country.
    Type of Medium: Online Resource
    Pages: XIII, 188 p. 29 illus., 24 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811614729
    Series Statement: Water Resources Development and Management,
    URL: https://doi.org/10.1007/978-981-16-1472-9
    DOI: 10.1007/978-981-16-1472-9
    DDC: 363.73
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  • 92
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    Pollution Control Technologies : Current Status and Future Prospects (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pollution. ; Environmental health. ; Environmental engineering. ; Biotechnology. ; Bioremediation. ; Pollution. ; Environmental Health. ; Environmental Engineering/Biotechnology.
    Description / Table of Contents: Pollution Control Technologies: Current Status and Future Prospect -- Remediation of Persistent Organic Pesticides from Wastewater Matrices‒ Present and Future Conceptions -- Uranium(VI) ions Removal from the Aqueous Environment: Current Treatment Technologies and its Future Prospects -- A Study on Different Bioremediation Approaches to Hexavalent Chromium -- Dissolved Arsenic in Groundwater Bodies: A Short Review of Remediation Technologies -- Occurrence, Fate and Removal of Microplastics in Sewage Treatment Plants (STPs) -- Membrane Technology for Desalination and Wastewater recycling -- Forward Osmosis in Desalination and Wastewater Treatment -- Food Processing Wastewater Treatment: Current Practices and Future Challenges -- Energy Analysis of Wastewater Infrastructure -- Prediction of Hospital visits for Respiratory Morbidity due to Air Pollutants in Lucknow -- Technologies for Controlling Particulate Matter Emissions from Industries.
    Abstract: This monograph is based on pollution control technologies available to deal with water and air pollution. It includes removal of variety of pollutants including arsenic, chromium, uranium, pesticides and arsenic from water using adsorption technique. In addition, this book deals with the sampling and removal of microplastics using various techniques. The contents also focus on the role of membrane technology in water and wastewater treatment, and particulate matter air pollution and its control techniques. This volume will be a useful guide for researchers, academics and scientists.
    Type of Medium: Online Resource
    Pages: XV, 290 p. 76 illus., 63 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811608582
    Series Statement: Energy, Environment, and Sustainability,
    URL: https://doi.org/10.1007/978-981-16-0858-2
    DOI: 10.1007/978-981-16-0858-2
    DDC: 363.73
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  • 93
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    Legacy and Emerging Contaminants in Water and Wastewater : Monitoring, Risk Assessment and Remediation Techniques (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Pollution. ; Environmental chemistry. ; Water. ; Hydrology. ; Public health. ; Refuse and refuse disposal. ; Environmental health. ; Pollution. ; Environmental Chemistry. ; Water. ; Public Health. ; Waste Management/Waste Technology. ; Environmental Health.
    Description / Table of Contents: Part 1: State of the science on organic micropollutants in water and wastewater -- Chapter 1-Emerging contaminants in water and wastewater: monitoring, risk assessment and remediation techniques -- Chapter 2-Legacy and emerging contaminants in water: Origin, distribution and implications for human exposure and health -- Chapter 3-Groundwater contamination by persistent organic pollutants in India- A review -- Chapter 4-Fate, Transport and Effects of Pharmaceuticals and Personal Care Products in Urban Environment -- Chapter 5-Phenoxyacid herbicides in water ecosystems- a review on their fate, risk assessment and remediation techniques -- Part 2: Monitoring of organic micropolluntants and their associated risks -- Chapter 6-Water contamination and sources of plasticizers in Asia: a review -- Chapter 7-Antifouling Strategies & Environmental Issues in Industrial Cooling Water Systems in the Marine Environment -- Chapter 8-Measuring emerging contaminants in freshwater systems -- Chapter 9-Optical Techniques in Monitoring of Persistent Organic Pollutants (POPs) in Water and Waste Water -- Part 3: Current approaches for remediation of organic micropollutants -- Chapter 10-Pharmaceuticals in Indian Aquatic Environment: Risk and Implications for Management -- Chapter 11-Suspect and Non-target Screening of Pharmaceuticals in Water and Wastewater Matrices -- Chapter 12-Human exposure and health risks -- Chapter 13-Carbamazepine Residues in Wastewater and River Water: Occurrence, Estimation of Use, and Disposal of this Drug in a Small Community in Western Kentucky, USA -- Chapter 14-Source, Treatment and Management Options of Contaminants of Emerging Concerns (CECs) in Water -- Chapter 15-Emerging Contaminants in Water: Potential Risks and Remedial Techniques -- Chapter 16-Emerging Contaminants Removal from Domestic Wastewater by Advanced Treatment Technologies -- Chapter 17-Treatment Technologies for Emerging Contaminants in Water and Wastewater -- Chapter 18-Novel strategies to treat organic micropollutants -- Chapter 19-Advanced treatment technologies to combat antibiotic resistant bacteria and antibiotic resistance genes from urban wastewater -- Chapter 20-Nanotechnology based treatment strategies for removal of antibiotic and antibiotic byproducts from waste water -- Chapter 21-Levels, sources and removal efficiency of PCDDs/PCDFs and dl-PCBs in water and wastewater in Poland and Europe under the European water directives.
    Abstract: This volume provides a collection of research findings on the distribution and risk associated with emerging contaminants (ECs) in water and wastewater across the globe, and effective remediation techniques and technologies. The book covers various monitoring techniques for ECs in water and wastewater and its related impacts on the ambient environment, and offers valuable information on cost-effective monitoring techniques and sustainable treatment technologies for ECs. The authors detail the risks and biological effects of ECs and legacy persistent organic pollutants (POPs) in freshwater and marine systems, including their adverse interactions with aquatic organisms, while also discussing the associated impacts on human health. The book comprehensively covers current research outcomes on treatment methods, cost-effectiveness, and infrastructure needs for effective removal of ECs. It will be of interest to students, researchers, and scholars in environmental science and engineering, water and wastewater, toxicology, environmental biotechnology, soil sciences, and microbial ecology.
    Type of Medium: Online Resource
    Pages: XII, 415 p. 137 illus., 99 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030954437
    Series Statement: Emerging Contaminants and Associated Treatment Technologies,
    URL: https://doi.org/10.1007/978-3-030-95443-7
    DOI: 10.1007/978-3-030-95443-7
    DDC: 363.73
    Language: English
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    Green Nanoremediation : Sustainable Management of Environmental Pollution (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Pollution. ; Green chemistry. ; Environmental chemistry. ; Pollution. ; Green Chemistry. ; Environmental Chemistry.
    Description / Table of Contents: Chapter. 1. Important Features of Nanomaterials for Environmental Remediation -- Part. I: Green nanoremediation: generating eco-friendly nanoremediators -- Chapter. 2. Green-synthesis of nanomaterials for environmental remediation -- Chapter. 3. Nanoremediation: main strategies, advantages and disadvantages - Strategic methods of nanoremediation through nanomaterials synthesized from microbes -- Chapter. 4. Fungi-based synthesis to generate nanomaterials to nanoremediation -- Chapter. 5. Algae-based synthesis to generate nanomaterials to nanoremediation -- Chapter. 6. Plant-based synthesis to generate nanomaterials to nanoremediation -- Chapter. 7. Innovations on the synthesis of metal nanoparticles to nanoremediation -- Part II: Important green nanomaterials in the management of environmental pollution -- Chapter. 8. Main green nanomaterials to water remediation -- Chapter. 9. Green non-carbon-based nanomaterials to environs remediation -- Chapter. 10. Green Iron nanoparticles for nanoremediation -- Chapter. 11. Green Silver nanoparticles for nanoremediation -- Part III: Conjugating nanoremediation to other remediation strategies -- Chapter. 12. Green-based nanomaterial and plants in nanophytoremediation strategies -- Chapter. 13. Main interactions of green nanomaterials and microorganisms on nanoremediation protocols -- Part. IV: Safety aspects and analysis of nanoremediation -- Chapter. 14. Supporting nanotechnology safety through nanoinformatics -- Chapter. 15. Conventional strategies of environmental pollution remediation versus Green Nanoremediation -- Chapter. 16. Using nanoremediation strategies: cost/benefit analysis -- Chapter. 17. Strategies to evaluate nanoremediation efficiency.
    Abstract: This book focuses on green nanoremediation addressing aspects related to the use of nanomaterials generated through green synthesis protocols to efficiently restore polluted environs. Nanomaterials’ characteristics such as large surface area, capacity to easily reach into contaminated sites, good reactivity, and possibility of being developed to present photocatalytic activity and/or to deal with targeted substances by chemical surface modification are useful specially to perform remediation. As an alternative to conventional physicochemical methods, the green-based synthesis protocols reject the use of harmful reagents, prevent waste production, apply renewable energy source and/or materials, and consider in first place offering the smallest negative impact possible to living beings and to the ecosystem. Green synthesis in nanotechnology field involves the use of seaweeds, bacteria, cyanobacteria, yeasts, fungi, plants (living ones, biomass, extracts) and/or bio-derived products to generate the nanomaterials. The introductory chapter will be dedicated to nanomaterials’ characteristics that enable them to be used in environmental remediation. The first part of the book will be dedicated to organic and inorganic pollution and the threats they pose to living forms; advantages, disadvantages and mechanisms of nanoremediation; comparison between conventional strategies of environmental pollution remediation and the green nanoremediation; carbon-based and non-carbon-based green nanomaterials capable of promoting environs’ remediation; cost/benefits of using nanomaterials and nanoinformatics to a safe nanotechnology. The second part will be dedicated to green nanoremediation of water and soil, microbe-based, algae-based and plant-based synthesis of nanomaterials to nanoremediation. This part will also contain chapters dedicated to relevant nanomaterials for green nanoremediation protocols, nano-phytoremediation strategies, strategies to evaluate the efficiency of protocols related to this kind of remediation, main interactions of green nanomaterials and microbes during nanoremediation and, as a consequence of it, biocompatibility of green nanomaterials. This book’s main purpose is to offer readers extensive knowledge on green nanoremediation as a feasible strategy to fight pollution's harmful consequences and clean environmental pollution, but also present the challenges that should be surpassed.
    Type of Medium: Online Resource
    Pages: XI, 388 p. 96 illus., 77 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031305580
    URL: https://doi.org/10.1007/978-3-031-30558-0
    DOI: 10.1007/978-3-031-30558-0
    DDC: 363.73
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    Managing Persistent Organic Pollutants in India : Case Studies on Vapi and Surat, Gujarat (2023)
    Cham :Springer Nature Switzerland :
    Details
    Keywords: Pollution. ; Environmental policy. ; Environmental health. ; Pollution. ; Environmental Policy. ; Environmental Health.
    Description / Table of Contents: Chapter 1 – Status of POPs Pollution in India -- Chapter 2 – Regulatory framework, Policies and Programs in POPs Management in India -- Chapter 3 – POPs Associated with Plastic Waste -- Chapter 4 – Transport of POPs from Source to Sea -- Chapter 5 – Environmental Monitoring Techniques of Targeted POPs -- Chapter 6 – Environmental and health impact -- Chapter 7 – International Regulatory Frameworks and Best Practices in Management of POPs -- Chapter 8 – Overview of Use and Release Sources of the Seven New POPs -- Chapter 9 – Analysis of Gaps in Management of POPs in India -- Chapter 10 – Case Studies-Tapi and Daman Ganga River Basins in Gujarat. .
    Abstract: Persistent Organic Pollutants (POPs) are a class of chemicals that are persistent, bio accumulative and toxic (PBT), which are restricted for use under the Stockholm Convention. They adversely impact the environment, human and animal health. Most of the POPs are semi-volatile organic compounds (SVOCs) and known to have a long-range transport potential and are often deposited in colder climate and found in places away from the regions they are produced. POPs are usually hydrophobic (i.e., “water-hating”) and lipophilic (i.e., “fat-loving”) chemicals, due to which they bind to solids, particularly organic matter, and fatty tissues in both marine and terrestrial environments. As a result, POPs may move up the food chain. This book focuses on determining the sources, fate, analytical techniques of detecting POPs as well as their health impacts. It further dwells on the regulatory aspects, management of POPs, best environmental practices (BEPs), Indian and international case studies, gaps in understanding the regulatory aspects. A few key recommendations for the way forward form the concluding chapters of this book.
    Type of Medium: Online Resource
    Pages: X, 200 p. 27 illus., 26 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031313110
    Series Statement: Emerging Contaminants and Associated Treatment Technologies,
    URL: https://doi.org/10.1007/978-3-031-31311-0
    DOI: 10.1007/978-3-031-31311-0
    DDC: 363.73
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    Strategies and Tools for Pollutant Mitigation : Research Trends in Developing Nations (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Pollution. ; Refuse and refuse disposal. ; Environmental chemistry. ; Agriculture. ; Pollution. ; Waste Management/Waste Technology. ; Environmental Chemistry. ; Agriculture.
    Description / Table of Contents: PartI. State of art and sustainable remediation approaches -- Chapter1. Utilizing organic wastes for probiotic and bioproduct development: a sustainable approach for management of organic waste -- Chapter2. Bioremediation as an alternative and sustainable strategy against environmental pollutants – A review on recent advances -- Chapter3. Recent developments on the application of nanomaterials in Environmental Remediation - A review -- Chapter4. Nano-Bioremediation: An Advanced Technique for Revitalizing the Tarnished Resource -- Chapter5. Application of Biochar in the remediation of contaminated soils as a viable approach for cleaner soil system – A review -- Chapter6. Vermitechnology- an eco-friendly approach for organic solid waste management and soil fertility improvement – a review -- Part2. Waste Management for a Cleaner Environment -- Chapter7. Propelling the future biofuel research: plant breeding, genomics and genetic engineering strategies for cleaner environment -- Chapter8. Microbial Approaches for Bioconversion of Agro-Industrial Wastes -- Chapter9. Contemporary approach for electronic waste management -- Chapter10. Waste recycling and the circular bioeconomy a comprehensive review of recent researches. .
    Abstract: This book offers an overview of the latest work in environmental remediation and waste management coming out of developing nations. It is split into two sections: one on state-of-the-art sustainable remediation approaches, and the other covering waste management for a cleaner environment The ten chapters in this book are structured as reviews that assimilate recent works in these areas; they provide a centralized resource for scholars in developing nations who are working in environmental remediation and waste management. The volume will be of interest to sustainability researchers, environmental engineers, industry managers and agricultural scientists.
    Type of Medium: Online Resource
    Pages: VI, 236 p. 30 illus., 27 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030982416
    URL: https://doi.org/10.1007/978-3-030-98241-6
    DOI: 10.1007/978-3-030-98241-6
    DDC: 363.73
    Language: English
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  • 97
    Online Resource
    Online Resource
    Water Resources Quality and Management in Baltic Sea Countries (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pollution. ; Water. ; Hydrology. ; Environmental management. ; Pollution. ; Water. ; Environmental Management.
    Description / Table of Contents: Introduction -- Assessment of Water Resources in Poland -- Surface Water Eutrophication in Poland: Assessment and Prevention -- Hydrogeological Conditions and Management of Groundwater Resources in Poland -- Water Resources in Lithuania -- Assessment of Water Resources Pollution in Lithuania -- Water Supply and Demand in Lithuania -- Wastewater Management in Lithuania -- Urban Rainwater Drainage in Lithuania -- Wastewater Sludge Management in Latvia -- Analysis of Factors Controlling Pathogen Destruction in Municipal Sludge During Handling -- Phosphors Fluxes in the Baltic Sea Region – a Meta Data Analysis -- Regulatory Scenarios to Counteract High Phosphors Inputs into the Baltic Sea -- Water Resources of the Russian Rivers of the Baltic Sea Basin and their Possible Changes under Global Warming -- Schemes of Complex Use and Protection of Water Objects in the Russian Part of the Baltic Sea Basin as a Basis for Water Resources Management -- Conclusions and Recommendations.
    Abstract: This unique book shares the knowledge and experience of experts and scientists who apply high-quality findings and input from their research to issues concerning the management of water resources and their quality in Baltic countries including Poland, Lithuania, Latvia, Germany and Russia. It summarizes the latest results of several systematic investigations, and assesses the occurrence and quality of surface and underground waters within the Baltic countries to help decision-makers plan for sustainable development. The book addresses a range of water resources management issues, especially those that are relevant to the water quality in these Baltic countries. It presents cutting-edge information and findings that can be effectively used to solve a variety of problems in integrated water resources management. Accordingly, it will be of interest to graduate students, researchers, water scientists, professionals, experts and practitioners working in water resources management.
    Type of Medium: Online Resource
    Pages: X, 321 p. 88 illus., 80 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030397012
    Series Statement: Springer Water,
    URL: https://doi.org/10.1007/978-3-030-39701-2
    DOI: 10.1007/978-3-030-39701-2
    DDC: 363.73
    Language: English
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  • 98
    Online Resource
    Online Resource
    Management of Water Quality and Quantity (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pollution. ; Sociology, Urban. ; Natural disasters. ; Pollution. ; Urban Sociology. ; Natural Hazards.
    Description / Table of Contents: Introduction -- Storm Water Management in Urban Areas -- The Green Roofs and Facades as a Tools of Climate Cooling in the Urban Environment -- Infiltration of Rainwater in Urban Areas -- Stream water Quality Modelling Techniques -- Water Quality in Czech Republic -- Xenobiotics in Urban Water Cycle -- Grey water reuse in Urban Areas -- The Necessary Documents for the Design Documentation for Water Supply and Sewerage Systems in Czech Republic -- Biological audits in the System of Water Treatment Control -- Monitoring Changes of Water Content in Soil Pores of Earth Dams -- Monitoring of Levees for Flood Protection Purposes -- Assessment of Flood Damages, Flood Risks and Flood Mitigation Measures -- Flood Protection -- Economy and management of water supply -- Management of drinking water resources in the region of South Moravia -- Small Hydropower Plants -- History and Present of the Laboratory of Water Management Research in Brno -- Conclusions and Recommendations.
    Abstract: This book focuses on water pollution, water management and water structures. Presenting contributions on water quality and quantity issues from the engineering point of view, it discusses a variety of issues, from storm water management in urban areas and water quantity, to hydraulic structures, hydrodynamic modeling and flood protection. The book also provides state-of-the-art insights, which can be used to effectively solve a variety of problems in integrated water resources management, and introduces the latest research advances. Edited and authored by pioneers in the field who have been at the forefront of water management development in the Czech Republic, this book is a valuable resource for environmental professionals, including scientists and policymakers, interested in water-related issues both in the Czech Republic and elsewhere.
    Type of Medium: Online Resource
    Pages: X, 409 p. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030183592
    Series Statement: Springer Water,
    URL: https://doi.org/10.1007/978-3-030-18359-2
    DOI: 10.1007/978-3-030-18359-2
    DDC: 363.73
    Language: English
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  • 99
    Online Resource
    Online Resource
    Water Resources Management in Balkan Countries (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pollution. ; Environmental management. ; Physical geography. ; Pollution. ; Environmental Management. ; Physical Geography.
    Description / Table of Contents: Water Resource in Slovenia -- Management of Artificial Groundwater Recharge in Slovenia -- Water Resources Management in North Macedonia -- Water Resources of Serbia and its Utilization -- Water Resources Management in Croatia -- An overview of Environmental Aspects of Water Resources in Croatia -- Water Management in the Agricultural Sector in Greece -- Water Resource Management in Bulgaria -- River Systems under the Anthropogenic and Climate Change Impacts: Bulgarian Case -- Development of Hydropower in Balkan Region -- Water Resources of Romania – Spatial and Temporal Variability -- Drought and Insolvency: Case study of the Producer-Buyer Conflict (Romania, the period between the year 2011-2012) -- Danube Delta Biosphere Reserve - Long Term Assessment of Water Quality -- Water quality and pollution status of the main rivers in the Republic of Macedonia -- Conclusions and Recommendations.
    Abstract: This book presents an overview and knowledgeable on water resources management in Balkan countries – Slovenia, North Macedonia, Serbia, Croatia, Greece, and Bulgaria. The book shows the state of the art and also the latest research findings of the different aspects of water resources management in Balkan countries with case studies that reveal the best practice in water resources management, development, and protection. Researchers and scientists from the Balkan countries present their experiences and expertise on a wide range of water resources topics. Therefore, the book is of particular interest to decisions planners/makers and stakeholders. Also, the book will be useful to experts, professionals, researchers, scientists, practitioners, academics working in the field of water resources management in Balkan countries and analogous regions.
    Type of Medium: Online Resource
    Pages: XIII, 469 p. 171 illus., 165 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030224684
    Series Statement: Springer Water,
    URL: https://doi.org/10.1007/978-3-030-22468-4
    DOI: 10.1007/978-3-030-22468-4
    DDC: 363.73
    Language: English
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  • 100
    Online Resource
    Online Resource
    Sensors in Water Pollutants Monitoring: Role of Material (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pollution. ; Refuse and refuse disposal. ; Electronic circuits. ; Pollution. ; Waste Management/Waste Technology. ; Electronic Circuits and Systems.
    Description / Table of Contents: Chapter 1: Materials in electrochemical detection of water pollutants -- Chapter 2: Materials in bio-sensing of water pollutants -- Chapter 3: Computational design of Nucleic acid-based Bioreceptor for Contaminants of Emerging Concern -- Chapter 4: Immunochromatographic Strip Based Sensor for the Detection of Water Pollutants -- Chapter 5: Emerging techniques and materials for water pollutants detection -- Chapter 6: Nanofiber based sensors for Water Pollution Monitoring -- Chapter 7: Introduction: Role of Materials in Sensors for Water Pollutants Monitoring -- Chapter 8: Water Pollutants: Origin and status.
    Abstract: This book discusses the sensitivity, selectivity, and response times of different sensor materials and their potential application in the design of portable sensor systems for monitoring water pollutants and remediation systems. Beginning with an overview on water pollutants and analytical methods for their detection, the book then moves on to describing the advances in sensor materials research, and the scope for their use in different types of sensors. The book lays emphasis on techniques such as colorimetric, fluorescence, electrochemical, and biological sensing of conventional and emerging pollutants. This book will serve as a handy guide for students, researchers, and professional engineers working in the field of sensor systems for monitoring water pollutants to address various challenges.
    Type of Medium: Online Resource
    Pages: X, 319 p. 77 illus., 71 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811506710
    Series Statement: Advanced Functional Materials and Sensors,
    URL: https://doi.org/10.1007/978-981-15-0671-0
    DOI: 10.1007/978-981-15-0671-0
    DDC: 363.73
    Language: English
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