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  • 1
    Online Resource
    Online Resource
    Coronary Artery Disease: Therapeutics and Drug Discovery (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Cardiology. ; Therapeutics. ; Heart Surgery. ; Pharmacology. ; Cardiology. ; Therapeutics. ; Cardiac Surgery.
    Description / Table of Contents: Coronary Artery Disease: From Mechanism to Clinical Practice -- Evidence in guidelines for treatment of coronary artery disease -- Revascularization For Coronary Artery Disease: Principle And Challenges -- Antithrombotic drugs: pharmacology and perspectives -- Lipid modifying drugs: pharmacology and perspectives -- Anti-hypertensive drugs: pharmacology and perspectives -- Pharmaceutical treatment for Heart failure -- Drug discovery for coronary artery disease.
    Abstract: This book provides an overview of the etiology of coronary artery disease and focuses on the main therapies and drug interventions currently available. It highlights drug pharmacology and therapeutic challenges, with a special emphasis on the underlying principles of available therapeutics and the on-going development of drugs for coronary artery disease. The book is divided into eight chapters, the first of which describes the classical mechanism of coronary artery disease and its clinical presentations. Chapter 2 lists the principles of and related evidence on the prevention and treatment of coronary artery disease. This includes diet and lifestyle management, and guidelines for the treatment of acute coronary syndrome and stable coronary artery disease. In turn, Chapter 3 describes revascularization treatments, covering percutaneous coronary interventions, coronary artery bypass grafts and thrombolysis. This chapter also addresses the main therapeutic challenges. The following chapters provide an overview of three major categories of coronary artery disease drugs, which target thrombosis (Chapter 4), lipid metabolism (Chapter 5), and hypertension (Chapter 6). Heart failure constitutes the major health burden in the late stage of coronary artery disease; accordingly, current heart failure therapeutics and related drug pharmacology are described in Chapter 7. In closing, Chapter 8 provides a summary of on-going clinical trials for coronary artery disease drug development and discusses a number of promising areas in which intensive research into new therapeutics is being pursued. Given its scope, the book will be of interest to clinicians, medical students and research scientists, as well as to pharmaceutical professionals who are seeking new therapies and drugs for coronary artery disease and related disorders.
    Type of Medium: Online Resource
    Pages: IX, 339 p. 7 illus., 4 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811525179
    Series Statement: Advances in Experimental Medicine and Biology, 1177
    URL: https://doi.org/10.1007/978-981-15-2517-9
    DOI: 10.1007/978-981-15-2517-9
    DDC: 615
    Language: English
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  • 2
    Online Resource
    Online Resource
    Pediatric Pharmacotherapy (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Pediatrics. ; Pharmacology. ; Pediatrics.
    Description / Table of Contents: Anti-epileptic drugs in pediatrics -- Current and new therapies for Duchenne Muscular Dystrophy -- Lysosomal diseases -- Mitochondriopathies -- Endocrinology thyroid, pituitary, growth stimulant, growth reduction -- Bone disease – bisphosphonates -- Diabetes type 1 and 3 (insulin; sulfonylurea; others) -- Diabetes type 2 (metformin etc.) -- Dermatology – part 1 urticaria, atopic dermatitis -- Dermatology part 2, ichtyosis, psoriasis -- Cardiovascular part 1- catcholamines, inotropic -- Cardiovascular part 2 – antiarhythmica, anti hypertensives -- Nephrology – dialysis -- How to use drugs in obese children and adolescents -- Haematology – CSFs, erythropoietin -- Antiretroviral/HIV -- Clinical pharmacology and pharmacometrics to better understand physiological changes during pregnancy and neonatal life -- Antihelminth treatment -- Inflammatory bowel disease -- Constipation; laxatives -- Psychiatric diseases in children and adolescents -- Oncology – cell reducing agents part 1, part 2, part 3 -- Immunosuppressants – organ transplantation -- Bone marrow/stem cell transplantation -- Narcotic sparing approaches and the shift towards paracetamol in neonatal intensive care -- Disorders of puberty: pharmacotherapeutic strategies for management.
    Abstract: This volume provides readers with the most updated scientific information on the efficacy and safety of medicines for children and adolescents. The book enriches the understanding of pediatric pharmacotherapy for health professionals, regulatory agencies, pharmaceutical companies and learned societies. It contains important information on the pharmacodynamics and pharmacokinetics of drugs. It summarizes the latest investigations on the effects of pharmacological treatments in relation to and dependent on age, gender, fat mass and disease status. Therefore and importantly, this volume reviews the latest data on how pharmacotherapy has to be adjusted and personalized in regards to stages of development and during the pediatric lifespan from neonate through adolescence. In addition, the topic of rare diseases and special challenges for pharmacotherapy will be included and will provide readers with the necessary knowledge to handle complex diseases and treatment strategies especially in relation to pharmacotherapy of rare and orphan diseases.
    Type of Medium: Online Resource
    Pages: VIII, 538 p. 1 illus. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030504946
    Series Statement: Handbook of Experimental Pharmacology, 261
    URL: https://doi.org/10.1007/978-3-030-50494-6
    DOI: 10.1007/978-3-030-50494-6
    DDC: 615
    Language: English
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  • 3
    Online Resource
    Online Resource
    Reactive Oxygen Species : Network Pharmacology and Therapeutic Applications (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Cardiology. ; Neurosciences. ; Clinical biochemistry. ; Pharmacology. ; Cardiology. ; Neuroscience. ; Medical Biochemistry.
    Description / Table of Contents: Part I: ROS Revisited: Changing the Focus from Oxidative Stress and Redox Biology to Redox Medicine -- Demystifying oxidative stress -- Oxidants in Physiological Processes -- Network Medicine-Based Unbiased Disease Modules for Drug and Diagnostic Target Identification in ROSopathies -- Part II Targeting antioxidant responses -- Development of Telintra as an Inhibitor of Glutathione S-Transferase P -- Perspectives on the Clinical Development of NRF2-Targeting Drugs -- Part III: Inhibiting ROS formation and toxification -- NOX Inhibitors: From Bench to Naxibs to Bedside -- Nitric Oxide Synthase Inhibitors into the Clinic at Last -- Xanthine Oxidoreductase Inhibitors -- Monoamine Oxidase Inhibitors: From Classic to New Clinical Approaches -- Inhibition of Myeloperoxidase -- Part IV: Stimulating/substituting ROS -- Effects of Mammalian Thioredoxin Reductase Inhibitors -- Cardiovascular Therapeutic Potential of the Redox Siblings, Nitric Oxide (NO•) and Nitroxyl (HNO), in the Setting of Reactive Oxygen Species Dysregulation -- Tetrahydrobiopterin and Nitric Oxide Synthase Recouplers -- Part V: Repairing ROS damage -- Soluble Guanylate Cyclase Stimulators and Activators – Peter Sander -- Inhibitors of Advanced Glycation End Product (AGE) Formation and Accumulation.
    Abstract: Reactive oxygen species (ROS) have been implicated in almost every human disease phenotype, without much, if any, therapeutic consequence foremost exemplified by the failure of the so-called anti-oxidants. This book is a game changer for the field and many clinical areas such as cardiology and neurology. The term ‘oxidative stress’ is abandoned and replaced with a systems medicine and network pharmacology-based mechanistic approach to disease. The ROS-related drugs discussed here target either ROS- forming or ROS -modifying enzymes for which there is strong clinical evidence. In addition, ROS targets are included as they jointly participate in causal mechanisms of disease. This approach is transforming the ROS field and represents a breakthrough in redox medicine indicating a path to patient benefit. In the coming years more targets and drugs may be discovered, but the approach will remain the same and this book will thus become, and for many years remain, the leading reference for ROSopathies and their treatment by network pharmacology. Chapter "Soluble Guanylate Cyclase Stimulators and Activators" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Type of Medium: Online Resource
    Pages: VIII, 425 p. 70 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030685102
    Series Statement: Handbook of Experimental Pharmacology, 264
    URL: https://doi.org/10.1007/978-3-030-68510-2
    DOI: 10.1007/978-3-030-68510-2
    DDC: 615
    Language: English
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  • 4
    Online Resource
    Online Resource
    Organotypic Models in Drug Development (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Medical genetics. ; Pathology. ; Pharmacology. ; Clinical Genetics. ; Pathology.
    Description / Table of Contents: Inflammatory skin disease models in vitro and in animals – predictability for drug development -- Neural In Vitro Models for Studying Substances Acting on the Central Nervous System -- Quality of commercial tissues Standardised Reconstructed Skin Models in Toxicology and Pharmacology: State of the Art and Future Development -- Human-Derived In Vitro Models Used for Skin Toxicity Testing Under REACh -- Disease Models: Lung models for testing drugs against inflammation and infection -- In Vitro Models of the Blood-Brain Barrier -- How Qualification of 3D Disease Models Cuts the Gordian Knot in Preclinical Drug Development -- The CAM Assay as an Alternative In Vivo Model for Drug Testing -- Organotypic Models in Drug Development “Tumor Models and Cancer Systems Biology for the Investigation of Anticancer Drugs and Resistance Development -- Tissue Engineering for Musculoskeletal Regeneration and Disease Modeling -- Immunocompetent human intestinal models in preclinical drug development -- Engineered Heart Muscle Models in Phenotypic Drug Screens.
    Abstract: This book provides latest findings in organotypic models in drug development and provides the scientific resonance needed in an emerging field of research in disciplines, such as molecular medicine, physiology, and pathophysiology. Today the research on human-based test systems has gained major interest and funding in the EU and the US has increased over the last years. Moreover, so-called 3R (reduce, replace, refine animal experiments) centres have been established worldwide.
    Type of Medium: Online Resource
    Pages: VIII, 323 p. 70 illus., 37 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030700638
    Series Statement: Handbook of Experimental Pharmacology, 265
    URL: https://doi.org/10.1007/978-3-030-70063-8
    DOI: 10.1007/978-3-030-70063-8
    DDC: 615
    Language: English
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  • 5
    Online Resource
    Online Resource
    Vaccination Strategies Against Highly Variable Pathogens (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Diseases. ; Virology. ; Immunology. ; Human physiology. ; Pharmacology. ; Diseases. ; Virology. ; Immunology. ; Human Physiology.
    Description / Table of Contents: Successful Vaccines -- Immunogenicity and Immunodominance in Antibody Responses -- Immunogen Design -- Adjuvants -- Tools to screen vaccines -- Targeting glycans on human pathogens for vaccine design -- BnAbs and highly antigenically variable pathogens.
    Abstract: Vaccines against antigenically stable pathogens, or pathogens that only exist in a limited number of serotypes, have been very successful in the past and have drastically decreased the incidence and lethality of many diseases. However, when it comes to highly variable pathogens or viruses that exist in multiple serotypes, the traditional methods for vaccine development have reached their limits. This volume highlights the development of vaccines against such challenging pathogens. Novel approaches for immunogen design, including structure-guided vaccine development and vaccines targeting glycans, as well as adjuvants and animal models used for testing possible vaccine candidates are outlined and discussed in detail. Given its scope, the book will appeal to scientists in the fields of infectious diseases, microbiology and medicine. .
    Type of Medium: Online Resource
    Pages: VII, 180 p. 16 illus., 15 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030580049
    Series Statement: Current Topics in Microbiology and Immunology, 428
    URL: https://doi.org/10.1007/978-3-030-58004-9
    DOI: 10.1007/978-3-030-58004-9
    DDC: 615
    Language: English
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  • 6
    Online Resource
    Online Resource
    Drug Stability and Chemical Kinetics (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Pharmacology. ; Pharmaceutics.
    Description / Table of Contents: 1 Principles of pharmaceutical analysis in drug stability and chemical kinetics -- 2 Guidelines for drug stability and stability testing -- 3 Chemical kinetics and its applications in drug stability -- 4 Methods and protocols for drug stability studies -- 5 Physical basis of degradation of pharmaceutical products -- 6 Role of microbiological degradation on drug stability -- 7 Role of decomposition on drug stability -- 8 Role of catalysis in drug stability -- 9 Analytical techniques for the assessment of drug stability -- 10 Stability of pharmaceutical products -- 11 Role of kinetic models in drug stability -- 12 Stability studies of vaccines -- 13 Stability studies of proteinous compounds -- 14 Stability studies of extemporaneous pharmaceutical products -- 15 Stability studies of parenteral products -- 16 Stability studies of solid dosage forms.
    Abstract: This book comprehensively reviews drug stability and chemical kinetics: how external factors can influence the stability of drugs, and the reaction rates that trigger these effects. Explaining the important theoretical concepts of drug stability and chemical kinetics, and providing numerous examples in the form of illustrations, tables and calculations, the book helps readers gain a better understanding of the rates of reactions, order of reactions, types of degradation and how to prevent it, as well as types of stability studies. It also offers insights into the importance of the rate at which the drug is degraded and/or decomposed under various external and internal conditions, including temperature, pH, humidity and light. This book is intended for researchers, PhD students and scientists working in the field of pharmacy, pharmacology, pharmaceutical chemistry, medicinal chemistry and biopharmaceutics. .
    Type of Medium: Online Resource
    Pages: XIV, 284 p. 22 illus., 13 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811564260
    URL: https://doi.org/10.1007/978-981-15-6426-0
    DOI: 10.1007/978-981-15-6426-0
    DDC: 615
    Language: English
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  • 7
    Online Resource
    Online Resource
    Handbook of 200 Medicinal Plants : A Comprehensive Review of Their Traditional Medical Uses and Scientific Justifications (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Pharmacy. ; Medicinal chemistry. ; Pharmacology. ; Pharmacy. ; Medicinal Chemistry.
    Description / Table of Contents: Abelmoschus maschatus -- Abrus precatorius -- Abutilon indicum -- Acacia catechu -- Acacia nilotica (A. arabica) -- Achillea millefolium -- Achyranthes aspera -- Aconitum napellus -- Acorus calamus -- Adiantum venustum (Adiantun capillus-veneris) -- Aegle marmelos -- Agrimonia eupatorium.-Alhagi maurorum -- Alkanna tinctoria -- Allium cepa -- Allium sativum -- Aloe vera -- Alpinia galangal -- Alpinia officinarum -- Alstonia scholaris -- Althaea officinalis -- Ammi majus -- Anacardium occidentale -- Anacyclus pyrethrum -- Andrographis paniculata -- Anethum graveolens -- Anthemis nobilis -- Apium graveolens -- Argemone Mexicana -- Aristolochia bracteolata -- Aristolochia fontanesii (A. longa) -- Aristolochia indica -- Aristolochia rotunda -- Artemisia absinthium -- Artemisia vulgaris -- Asparagus adscendens -- Asparagus officinalis -- Asparagus racemosus -- Atropa belladonna -- Azadirachta indica -- Bacopa monnieri -- Bauhinia tomentosa -- Berberis Aristata -- Berberis vulgaris -- Bombyx mori -- Borago officinalis -- Boswellia serrata -- Brassica nigra -- Butea monosperma -- Caccinia macranthera var. glauca (C. glauca) -- Caesalpinia bonduc (Caesalpinia bonducella) -- Cannabis sativa -- Capparis spinosa -- Cardiospermum halicacabum -- Carthamus tinctorius -- Carum carvi -- Cassia fistula -- Catharanthus roseus -- Celastrus paniculatus -- Centaurea behen -- Centella asiatica -- Chamaecrista absus (Cassia absus) -- Chamaemelum nobile (Anthemis nobilis) -- Cheilocostus speciosus (Costus Speciosus) -- Cichorium intybus -- Cinnamomum camphora -- Cinnamomum cassia -- Cinnamomum verum (C. zeylanicum) -- Citrullus colocynthis -- Clitoria ternatea -- Colchicum autumnale -- Colchicum luteum -- Commiphora gileadensis (C. opobalsamum) -- Commiphora myrrha -- Commiphora wightii (C. mukul) -- Convolvulus scammonia -- Cotoneaster nummularius -- Crocus sativus -- Croton tiglium -- Cullen corylifolium (Psoralea corylifolia) -- Cuminum cyminum -- Curcuma aromatica -- Curcuma longa -- Curcuma zedoaria -- Cuscuta chinensis -- Cuscuta reflexa -- Cydonia oblonga -- Cymbopogon schoenanthus -- Cyperus rotundus -- Datura stramonium -- Delphinium denudatum -- Dolichousnea longissimi (Usnea longissima) -- Doronicum pardalianches -- Embelia ribes -- Euphorbia hirta -- Euphorbia resinifera -- Ferula assa-foetida -- Ficus carica -- Ficus racemosa -- Foeniculum vulgare -- Fumaria officinalis -- Gentiana lutea -- Glycyrrhiza glabra -- Gymnema sylvestre -- Helleborus niger -- Hemidesmus Indicus -- Hibiscus rosa-sinensis -- Holarrhena pubescens (Holarrhena antidysenterica) -- Hyoscyamus niger -- Hyssopus officinalis -- Illicium verum -- Iris germanica -- Juniperus communi -- Justicia adhatoda (Adhatoda vasica) -- Lactuca sativa -- Lavandula stoechas -- Lawsonia inermis -- Lepidium sativum -- Linum usitatissimum -- Lupinus albus -- Malva sylvestris -- Marrubium vulgare -- Matricaria chamomilla -- Melia azedarach -- Melilotus officinalis -- Melissa officinalis -- Mesua ferrea -- Momordica charantia -- Moringa oleifera -- Myristica fragrans -- Myrtus communis -- Nageia nagi -- Nepeta cataria -- Nigella sativa -- Ocimum basilicum -- Ocimum gratissimum -- Ocimum tenuiflorum (Ocimum sanctum -- Operculina turpethum -- Paeonia emodi -- Pandanus odorifer (Pandanus Odoratissimus) -- Papaver somniferum -- Persicaria bistorta -- Phyllanthus emblica (Emblica officinalis) -- Picrorhiza kurroa -- Pimpinella anisum -- Piper cubeba -- Piper nigrum -- Pistacia lentiscus -- Plantago major -- Plantago ovata -- Plumbago zeylanica -- Polygonum aviculare -- Portulaca oleracea -- Quercus infectoria -- Rauvolfia serpentina -- Rheum emodi -- Rheum officinale -- Ricinus communis -- Rubia cordifolia -- Rumex vesicarius -- Ruta graveolens -- Salix caprea -- Salvia officinalis -- Santalum album -- Saussurea lappa -- Semecarpus anacardium -- Senna alexandrina -- Senna occidentalis -- Senna tora -- Sida cordifolia -- Smilax china;- Solanum americanum (S. nigrum) -- Sterculia urens -- Strychnos nux-vomica -- Swertia chirata -- Symplocos racemosa -- Syzygium cumini (Eugenia jambolana) -- Tamarindus indica -- Taraxacum officinale -- Taxus baccata -- Tephrosia purpurea -- Terminalia bellirica -- Terminalia chebula -- Thymus vulgaris -- Tinospora cordifolia -- Trachyspermum ammi (Ptychotis coptica) -- Tribulus terrestris -- Trigonella foenum-graecum -- Tussilago farfara -- Valeriana jatamansi (Nardostachys jatamansi) -- Verbena officinalis -- Vernonia anthelmintica (Baccharoides anthelmintica) -- Vigna unguiculata (Dolichos biflorus) -- Viola odorata -- Viscum album -- Withania somnifera -- Wrightia tinctoria -- Zingiber officinale -- Zingiber zerumbet -- Ziziphus jujuba -- Abbreviations -- Glossary -- Ayurvedic Terms of Diseases -- List of Referenced Books -- Index.
    Abstract: This book is designed to provide pharmacologists and researchers of natural products a comprehensive review of 200 medicinal plants, their vernacular names in various languages and their medicinal uses around the world, and in some cases, a historical perspective. Chemical constituents of each plant with the putative active constituent, and available up to date pharmacological studies (until 2017 on PubMed) with each medical activity explored and its relationship with traditional uses, are described for each plant. Any variations in chemical constituents and their effects on pharmacological studies outcome have been highlighted. All clinical trials conducted, with sufficient details, have been included. Nationalities and racial identities of participants of clinical trials are identified to impress upon the social, cultural and dietary influences on the clinical outcomes. Toxicity studies and potential interactions with prescribed drugs, and full spectrum of references are included.
    Type of Medium: Online Resource
    Pages: XXX, 2156 p. 199 illus., 198 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030168070
    URL: https://doi.org/10.1007/978-3-030-16807-0
    DOI: 10.1007/978-3-030-16807-0
    DDC: 615
    Language: English
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  • 8
    Online Resource
    Online Resource
    Therapeutic Applications of Dopamine D3 Receptor Function : New Insight After 30 Years Of Research (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Neurosciences. ; Psychiatry. ; Pharmacology. ; Neuroscience. ; Psychiatry.
    Description / Table of Contents: Preface -- A Historic Review of the D3 Dopamine System from D3 Cloning to Clinical Trials in Schizophrenia and Drug Addiction -- Location, Location, Location: The Expression of D3 Dopamine Receptors in the Nervous System -- Recent Advances in Dopamine D3 Receptor Heterodimers: Focus on Dopamine D3 and D1 Receptor-Receptor Interaction and Striatal Function -- Involvement of DA D3 Receptor and Mitochondrial Functions in Structural Neuroplasticity of the Emotional Brain Circuits: Possible Role in Depression -- Dopamine D3 Receptor in Parkinson Disease: A Prognosis Biomarker and an Intervention Target -- Dopamine D3 Receptors: A Potential Target to Treat Motivational Deficits in Parkinson’s Disease -- Therapeutic Challenges of Cognitive Dysfunctions in Neuropsychiatric Disorders: Focus on the Dopamine D3 Receptor -- Dopamine D3 Receptor in Stimulant and Opiate Use Disorders -- The Role of D3 Dopamine-Receptors in Nicotine Dependence: A Synthesis of the Pre-Clinical and Clinical Literature -- The Dopamine D3 receptor in Food Addiction -- The Dopamine D3 Receptor Pharmacology and the Therapeutic Use of D3 Receptor Ligands in Schizophrenia -- D3 receptors and Restless Legs Syndrome -- D3 receptors and PET imaging.
    Abstract: The CTBN volume Therapeutic Applications of Dopamine D3 Receptor Function reviews the state of the knowledge on the dopamine D3 receptor and its role in human behavior and disease (i.e.: neuropsychiatric illnesses including schizophrenia, mood disorders, Parkinson’s disease, restless legs syndrome, addictions and substance use disorders). The volume is written by leading experts across multidisciplinary areas (imaging, biobehavioral testing and clinical trials, preclinical models / molecular pharmacology) converging on the therapeutic implications / potential of the D3 receptor. The D3 dopamine receptor is a member of the D2-like family of G protein-coupled receptors. It was cloned and characterized almost 25 years ago. A key feature of the D3 dopamine receptor system, which has attracted considerable attention, is its anatomical localization remarkably restricted to the limbic circuitry. This has spurred the hypothesis that D3 involvement could contribute to the pathophysiology of neuropsychiatric disorders (or to some features of neuropsychiatric disorders), including but not limited to psychosis, addictions and substance abuse, mood and movement disorders.
    Type of Medium: Online Resource
    Pages: VIII, 275 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031230585
    Series Statement: Current Topics in Behavioral Neurosciences, 60
    URL: https://doi.org/10.1007/978-3-031-23058-5
    DOI: 10.1007/978-3-031-23058-5
    DDC: 615
    Language: English
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  • 9
    Online Resource
    Online Resource
    Approaching Complex Diseases : Network-Based Pharmacology and Systems Approach in Bio-Medicine (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Bioinformatics. ; Oncology. ; Medicine Philosophy. ; Pharmacology. ; Computational and Systems Biology. ; Oncology. ; Philosophy of Medicine.
    Description / Table of Contents: Chapter 1. Revisiting the concept of human disease (Mariano Bizzarri, Mirko Minini, and Noemi Monti) -- Chapter 2. Dynamical aspects of pharmacokinetic/pharmacodynamics and quantitative systems pharmacology models (Ioannis Loisios-Konstantinidis, Panteleimon D. Mavroudis, Panos Macheras) -- Chapter 3. The efficiency of multi-target drugs: a network approach (Lucas N. Alberca, Alan Talevi) -- Chapter 4. Mining Complex Biomedical Literature for Actionable Knowledge on Rare Diseases (Vinicius M. Alvesa, Stephen J. Capuzzia, Nancy Baker, Eugene N. Muratov, Alexander Trospsha, and Anthony J. Hickey) -- Chapter 5. Big Data, Personalized Medicine and Network Pharmacology: beyond the current paradigms (Alessandro Giuliani and Virginia Todde) -- Chapter 6. Epigenetic Control Using Small Molecules in Cancer (Tomohiro Kozako, Yukihiro Itoh, Shinichiro Honda, Takayoshi Suzuki) -- Chapter 7. Multiscale Modelling of Cancer: Micro-, Meso- and Macro-scales of Growth and Spread (Mark AJ Chaplain) -- Chapter 8. Precision Oncology vs Phenotypic approaches in the management of cancer: a case for the postmitotic state (Armando Aranda-Anzaldo and Myrna A.R. Dent) -- Chapter 9. Migrastatics - anti-metastatic drugs targeting cancer cell invasion (Aneta Gandalovičová , Daniel Rosel , Jan Brábek) -- Chapter 10. Critical steps in Epithelial-Mesenchymal transition as target for cancer treatment (Evgeny V. Denisov, Mohit Kumar Jolly, Vitaly P. Shubin, Alexey S. Tsukanov, Nadezhda V. Cherdyntseva) -- Chapter 11. Targeting the tumor-associated macrophages for ‘normalizing’ cancer (Julia Kzhyshkowska) -- Chapter 12. Tumor Reversion induced by embryo and oocyte extracts (Sara Proietti, Andrea Pensotti and Alessandra Cucina) -- Chapter 13. Trabectedin, a drug acting on both cancer cells and the tumor microenvironment (Paola Allavena, Manuela Liguori, Cristina Belgiovine) -- Chapter 14. Advances in Characterizing Recently-identified Molecular Actions of Melatonin: Clinical Implications (Russel J. Reiter, Ramaswamy Sharma, Sergio A. Rosales-Corral, Ana Coto-Montes, Jose Antonio Boga, Jerry Vriend) -- Chapter 15. Multitarget activities of Inositol and Inositol Hexakisphosphate (Ivana Vucenik) -- Chapter 16. Integration of Phytochemicals and Phytotherapy into Cancer Precision Medicine (Nadire Özenver and Thomas Efferth) -- Chapter 17. Synergistic Effects of Chinese Herbal Medicine and Biological Networks (Deep Jyoti Bhuyan, Saumya Perera1, Kirandeep Kaur, Muhammad A. Alsherbiny, Mitchell Low, Sai-Wang Seto, Chun-Guang Li, Xian Zhou) -- Chapter 18. Medicinal herbs: its therapeutic use in obstetrics and gynaecology (Irene Orbe, Daniel Paz, Leyre Pejenaute, Andrea Puente, Laura Diaz de Alda, Sandra Yague, Iñaki Lete) -- Chapter 19. Overcoming Antibiotic Resistance: New Perspectives (Matteo Bassetti, Elda Righi).
    Abstract: This volume – for pharmacologists, systems biologists, philosophers and historians of medicine – points to investigate new avenues in pharmacology research, by providing a full assessment of the premises underlying a radical shift in the pharmacology paradigm. The pharmaceutical industry is currently facing unparalleled challenges in developing innovative drugs. While drug-developing scientists in the 1990s mostly welcomed the transformation into a target-based approach, two decades of experience shows that this model is failing to boost both drug discovery and efficiency. Selected targets were often not druggable and with poor disease linkage, leading to either high toxicity or poor efficacy. Therefore, a profound rethinking of the current paradigm is needed. Advances in systems biology are revealing a phenotypic robustness and a network structure that strongly suggest that exquisitely selective compounds, compared with multitarget drugs, may exhibit lower than desired clinical efficacy. This appreciation of the role of polypharmacology has significant implications for tackling the two major sources of attrition in drug development, efficacy and toxicity. Integrating network biology and polypharmacology holds the promise of expanding the current opportunity space for druggable targets.
    Type of Medium: Online Resource
    Pages: XVI, 483 p. 49 illus., 41 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030328573
    Series Statement: Human Perspectives in Health Sciences and Technology, 2
    URL: https://doi.org/10.1007/978-3-030-32857-3
    DOI: 10.1007/978-3-030-32857-3
    DDC: 615
    Language: English
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  • 10
    Online Resource
    Online Resource
    Pharmacology of Potassium Channels (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Human physiology. ; Neurosciences. ; Pharmacology. ; Human Physiology. ; Neuroscience.
    Description / Table of Contents: Comparison of K+ Channel families -- High-resolution structures of K+ channels -- Pharmacological approaches to studying potassium channels -- Cardiac K+ channels and channelopathies -- Cardiac hERG K+ channel as safety and pharmacological target -- Pharmacology of A-type K+ channels -- Kv7 channels and hyperexcitability disorders -- Pharmacological activation of neuronal voltage-gated Kv7/KCNQ/M-channels for potential therapy of epilepsy and pain -- Potassium channels in cancer -- Kir channel molecular physiology, pharmacology and therapeutic implications -- The pharmacology of ATP-sensitive K+ channels (KATP) -- Calcium-activated K+ channels (KCa) and therapeutic implications -- The Pharmacology of two-pore domain potassium channels -- Control of biophysical and pharmacological properties of potassium channels by ancillary subunits -- Peptide toxins targeting KV channels -- Therapeutic antibodies targeting potassium ion channels.
    Abstract: The aim of the present book is to comprehensively review current advances in understanding of genetics, structural biology, pharmacology of potassium channels and their roles in disease as well as to identify current gaps in knowledge. The ultimate goal is to provide a scientific foundation for better understanding of modulatory mechanisms and pharmacology of potassium channels and to use this understanding to drive future drug discovery. This book will be a must-have for academic and industrial scientists interested in physiology, pharmacology, pathology and structure-functional relationships of ion channels. The book will also be helpful for lecturers and students in the college and university classrooms, as well as for anyone interested in the state-of-the art in modern cell biology, physiology and pharmacology. .
    Type of Medium: Online Resource
    Pages: VIII, 545 p. 70 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030840525
    Series Statement: Handbook of Experimental Pharmacology, 267
    URL: https://doi.org/10.1007/978-3-030-84052-5
    DOI: 10.1007/978-3-030-84052-5
    DDC: 615
    Language: English
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  • 11
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    Online Resource
    Nutritional Toxicology (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Nutrition   . ; Food science. ; Pharmacology. ; Nutrition. ; Food Science.
    Description / Table of Contents: 1 Preface -- 2 Effects of Nutrients/nutrition on Toxicants/toxicity -- 3 Effects of Xenobiotics on Nutrition -- 4 Effects of Antinutritional Factors on the Digestibility, Bioavailability and Quality of Protein -- 5 Natural Toxicants Originating from Food/Diet -- 6 Food contaminants -- 7 Food additives -- 8 Food contact materials -- 9 Genetically modified food -- 10 Tolerable upper limits of nutrients -- 11 Risk assessment and Risk-benefit assessment -- 12 Nutrients/Nutrition and Drug Interaction -- 13 Phytochemicals and Health -- 14 Adverse Effects of Phytochemicals.
    Abstract: This book provides a broad overview of the chemicals in food that have the potential to induce adverse health effects. Nutritional Toxicology is an interaction of nutrition, toxicology, biochemistry and food science, etc. Its main research scope involves the effects of nutrients on metabolisms of toxicants and their mechanisms, the interaction of the toxicants and contaminants originated from diet with nutrients and nutrition process, the adverse health outcome of nutrients excess, as well as methodology of research and related food and nutrition regulation process. Also the risk assessment of toxicants and contaminants in foods, and risk benefit assessment of nutrients (dietary supplementation) has become an emerging topic. This book provides novel and provocative insights into the fields of nutrition, food science and toxicology. It also offers a state-of-the-art report on recent discoveries concerning nutritional toxicology and where the field is going. It mainly focuses on advances made over the past 20 years. It will benefit graduate students, researchers and food and nutrition related regulation parties.
    Type of Medium: Online Resource
    Pages: X, 384 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811908729
    URL: https://doi.org/10.1007/978-981-19-0872-9
    DOI: 10.1007/978-981-19-0872-9
    DDC: 615
    Language: English
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  • 12
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    Online Resource
    Network Pharmacology (2021)
    Singapore :Springer Nature Singapore :
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    Keywords: Pharmacology. ; Pharmacy. ; Bioinformatics. ; Pharmacology. ; Pharmacy. ; Bioinformatics.
    Description / Table of Contents: Chapter 1. 'Network Target' Theory and Network Pharmacology -- Chapter 2. Application of Network Pharmacology Based on Artificial Intelligence Algorithm in Drug R & D -- Chapter 3. Commonly used Network Pharmacology Database -- Chapter 4. Commonly used Network Pharmacology Software -- Chapter 5. Network Pharmacology and TCM Modernization Case Studies -- Chapter 6. Network Pharmacology and Modern Drug R & D Cases -- Chapter 7. Drug-based Network Pharmacology Practice Process -- Chapter 8. Disease-based Network Pharmacology Practice Process -- Chapter 9. Drug-disease-based Network Pharmacology Practice Process.
    Abstract: This book introduces “network pharmacology” as an emerging frontier subject of systematic drug research in the era of artificial intelligence and big data. Network Pharmacology is an original subject of fusion system biology, bioinformatics, network science and other related disciplines. It emphasizes on starting from the overall perspective of the system level and biological networks, the analysis of the laws of molecular association between drugs and their treatment objects, reveals the systematic pharmacological mechanisms of drugs, and guides the research and development of new drugs and clinical diagnosis and treatment. After it was proposed, network pharmacology has been paid attention by researchers, and it has been rapidly developed and widely used. In order to systematically reveal the biological basis of diagnosis and treatment in traditional Chinese medicine and modern medicine, we proposed a new concept of "network target" for the first time, which has become the core theory of "network pharmacology". The core principle of a network target is to construct a biological network that can be used to decipher complex diseases. The network is then used as the therapeutic target, to which multicomponent remedies are applied. This book mainly includes four parts: 1) The concept and theory of network pharmacology; 2) Common analysis methods, databases and software in network pharmacological research; 3) Typical cases of traditional Chinese medicine modernization and modern drug research based on network pharmacology; 4) Network pharmacology practice process based on drugs and diseases.
    Type of Medium: Online Resource
    Pages: XVII, 468 p. 163 illus., 119 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811607530
    URL: https://doi.org/10.1007/978-981-16-0753-0
    DOI: 10.1007/978-981-16-0753-0
    DDC: 615
    Language: English
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  • 13
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    Online Resource
    Environment and Female Reproductive Health (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Midwifery. ; Public health. ; Pharmacology. ; Midwifery. ; Public Health.
    Description / Table of Contents: Part I Environmental Harmful Factors -- 1 Introduction to Environmental Harmful Factors -- Part II Female Reproductive Processes and Diseases -- 2 Introduction of Female Reproductive Processes and Reproductive Diseases -- Part III Effects of Environmental Factors on Reproductive Process -- 3 The Influence of Environmental Factors on Ovarian Function, Follicular Genesis, and Oocyte Quality -- 4 Effects of environment and lifestyle factors on premature ovarian failure -- 5 Effects of Environment and Lifestyle Factors on Anovulatory Disorder -- 6 Effects of Cigarette Smoking on Preimplantation Embryo Development -- 7 Toxicical effects of BPDE on dysfunctions of female trophoblast cells -- 8 The Roles of Stress-Induced Immune Response in Female Reproduction -- 9 Effects of Environmental EDCs on Oocyte Quality, Embryo Development and the Outcome in Human IVF Process -- Part IV Effects of Environmental Factors on Reproductive Diseases -- 10 Effects of environmental endocrine-disrupting chemicals on female reproductive health -- 11 Definition and Multiple Factors of Recurrent Spontaneous Abortion -- 12 The Variations of Metabolic Detoxification Enzymes Lead to Recurrent Miscarriage and their Diagnosis Strategy -- Part V Effects of Environmental Factors on Fertility Preservation -- 13 The Effects of Negative Elements in Environment and Cancer on Female Reproductive System.
    Abstract: This book will focus on the harmful effect of environmental toxins on female reproductive health. Reproduction is the basis of the continuation of human beings, and environment is the basis of human survival. However, environmental pollution has become a potential risk factor for human reproductive health, which not only leads to many chronic diseases, but also causes certain harm to reproductive health. Compared to male reproduction, female reproductive process is more complex, the reproductive system is more fragile, and is more vulnerable to be damaged. The aim of this book is to review the research progress, to address the challenges, and to stimulate the development in the direction of environment and female reproductive health.
    Type of Medium: Online Resource
    Pages: XI, 313 p. 13 illus., 10 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789813341876
    Series Statement: Advances in Experimental Medicine and Biology, 1300
    URL: https://doi.org/10.1007/978-981-33-4187-6
    DOI: 10.1007/978-981-33-4187-6
    DDC: 615
    Language: English
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  • 14
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    Online Resource
    Organic Cation Transporters in the Central Nervous System (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Human physiology. ; Molecular biology. ; Pharmacology. ; Human Physiology. ; Molecular Biology.
    Description / Table of Contents: General Overview of Organic Cation Transporters in Brain -- Organic Cation Transporter Expression and Function in the CNS -- Genetic and Epigenetic Regulation of Organic Cation Transporters -- Experimental Methods for Investigating Uptake 2 Processes In Vivo -- Substrates and inhibitors of OCTs and PMAT and therapeutic implications -- Organic Cation Transporters in Brain Histamine Clearance: Physiological and Psychiatric Implications -- Organic Cation Transporters in Brain Catecholamine Homeostasis -- The Interaction of Organic Cation Transporters 1-3 and PMAT with Psychoactive Substances -- Organic Cation Transporters in Psychiatric Disorders -- Organic Cation Transporters and Nongenomic Glucocorticoid Action -- Brain Plasma Membrane Monoamine Transporter in Health and Disease -- Regulation of Neurogenesis by Organic Cation Transporters: Potential Therapeutic Implications -- Organic Cation Transporter (OCT/OCTN) Expression at Brain Barrier Sites: Focus on CNS Drug Delivery.
    Abstract: Rapidly growing interest in the role of organic cation transporters (OCTs) and plasma membrane monoamine transporter (PMAT) in central monoamine homeostasis makes this book especially timely, given its thematic alignment with the role of OCTs and PMAT in CNS. This book discusses latest insights into the field laying an emphasis on health, disease and therapeutics. The chapter, “General Overview of Organic Cation Transporters in Brain”, of this book is available open access under a CC BY 4.0 license at link.springer.com.
    Type of Medium: Online Resource
    Pages: XII, 328 p. 70 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030829841
    Series Statement: Handbook of Experimental Pharmacology, 266
    URL: https://doi.org/10.1007/978-3-030-82984-1
    DOI: 10.1007/978-3-030-82984-1
    DDC: 615
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  • 15
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    Online Resource
    The Carbonic Anhydrases: Current and Emerging Therapeutic Targets (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Clinical biochemistry. ; Pharmacy. ; Pharmacology. ; Medical Biochemistry. ; Pharmacy.
    Description / Table of Contents: Dedication -- Preface.-The carbonic anhydrases in health and disease -- Carbonic anhydrase isozymes as diagnostic biomarkers and therapeutic targets -- Targeting carbonic anhydrases in vascular and pulmonary disease -- Carbonic anhydrase inhibitors in ophthalmology: glaucoma and macular oedema -- Targeting carbonic anhydrase isozymes in the treatment of neurological disorders -- Potential of carbonic anhydrase inhibitors in the treatment of oxidative stress and diabetes -- An overview of carbonic anhydrase-related neoplasms -- The carbonic anhydrase IX interactome and the regulation of cancer progression -- Carbonic anhydrase IX: current and emerging therapies -- Carbonic anhydrase inhibitors: designing isozyme-specific inhibitors as therapeutic agents -- Carbonic anhydrase inhibitors: identifying therapeutic cancer agents through virtual screening -- Targeting carbonic anhydrase IX in tumour imaging and theranostic cancer therapy.
    Abstract: This volume assembles and integrates the wealth of diverse information that is now accumulating in this burgeoning field. The existing and potential therapeutic applications of targeting CA cover a remarkably wide-range of diseases and disorders and have generated increasing and extensive interest in recent years. Its inter-disciplinary approach embraces both the most up-to-date therapeutic application of CA-targeting and the latest research data that will provide a platform for the development of novel applications. The interested audience comprises scientists and clinicians from many relevant disciplines within science and medicine.
    Type of Medium: Online Resource
    Pages: XII, 288 p. 38 illus., 22 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030795115
    Series Statement: Progress in Drug Research, 75
    URL: https://doi.org/10.1007/978-3-030-79511-5
    DOI: 10.1007/978-3-030-79511-5
    DDC: 615
    Language: English
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  • 16
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    Online Resource
    Pharmacology of the WNT Signaling System (2021)
    Cham :Springer International Publishing :
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    Keywords: Pharmacology. ; Physiology. ; Oncology. ; Neurosciences. ; Developmental biology. ; Pharmacology. ; Physiology. ; Oncology. ; Neuroscience. ; Developmental Biology and Stem Cells.
    Description / Table of Contents: Pharmacological thinking in WNT signaling -- Controlling WNT Signaling Specificity and implications for targeting WNTs pharmacologically -- WNTs on exosomes -- Strategies to target LRPs in WNT signaling -- Targeting the receptor tyrosine kinase ROR1 by small molecules -- Assessing WNT binding and Frizzled activation employing genetically encoded, biophysical sensors -- Disheveled proteins as crucial mediators of WNT signaling -- Destruction complex and regulation of CTNNB1 -- Strategies to therapeutically target WNT/PCP like signaling in disease -- Mining natural compounds to target WNT signaling - from mushrooms to corals -- FZD7 as a therapeutic target in intestinal cancer -- Targeting oncogenic WNT signaling with WNT derived peptides -- Targeting WNT signaling in lung pathology -- The role of WNT signaling in osteoarthritis and the therapeutic potential of its pharmacological targeting -- WNT signaling in Alzheimers disease and other neurodegenerative disorders - opportunities for therapy? -- Targeting WNT signaling as a risk.
    Abstract: This book reflects the state of the art of our understanding of the WNT signaling system, which comprises a network of signaling pathways initiated by the secreted WNT lipoglycoproteins, which are crucial for embryonal development, stem cell regulation, tissue homeostasis and repair. Dysfunction of this evolutionarily conserved signaling system leads to many diseases including developmental disorders, diverse forms of cancer, fibrosis, neurodegenerative disease and many more. The WNT signaling system is built upon 19 mammalian, secreted WNT lipoglycoproteins that interact with a plethora of distinct receptors, such as the G protein-coupled receptors called Frizzleds (FZD1-10), LDL receptor-like proteins (LRP5/6), receptor tyrosine kinases (ROR1, 2, RYK and PTK7). In addition, WNT pathways are tightly regulated by many secreted and cell-intrinsic negative regulators, such as soluble FZD-related proteins (SFRPs), Dickkopfs (DKKs), WNT-inhibitory proteins, TIKI, RNF43 and more. Understanding the basic mechanism in terms of receptor-ligand interaction, receptor selectivity, signal initiation and desensitization remain poorly understood, even though substantial advances have been made the recent years. Due to the involvement of the WNT signaling system in human disease, it appears obvious to target diverse branches pharmacologically and therapeutically. However, given the complexity of the system and its importance for stem cell regulation and tissue maintenance, therapy comes with obvious risks for severe side effects. The field is addressing the challenge to identify suitable targets and selective compounds for therapy allowing disease-selective therapeutic effects and balancing unwanted side effects. This book summarizes the current understanding of the basic and applied pharmacology in the WNT signaling system and bridges disciplines such as pharmacology, physiology, neurosciences, oncology and drug development.
    Type of Medium: Online Resource
    Pages: VIII, 422 p. 70 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030854997
    Series Statement: Handbook of Experimental Pharmacology, 269
    URL: https://doi.org/10.1007/978-3-030-85499-7
    DOI: 10.1007/978-3-030-85499-7
    DDC: 615
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  • 17
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    Online Resource
    The Art of Carbohydrate Analysis (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Chemistry, Organic. ; Food science. ; Biotechnology. ; Pharmacology. ; Organic Chemistry. ; Food Science. ; Biotechnology.
    Description / Table of Contents: Chapter 1 The World of Carbohydrates -- Chapter 2 Basic Knowledge of Glycobiology -- Chapter 3 Carbohydrates involved in Diseases -- Chapter 4 Detection of Carbohydrate by Colorimetric Methods -- Chapter 5. Analytical Techniques to Study Carbohydrates -- Chapter 6 Monosaccharide Composition Analysis -- Chapter 7 Carbohydrate Analysis of Glycoconjugates -- Chapter 8 Structural Characterization of Released Glycans -- Chapter 9 Analysis of Sialic Acids -- Chapter 10 Carbohydrate Microarray Technology -- Chapter 11 Analysis of Carbohydrates by Mass Spectrometry -- Chapter 12 Analysis of Carbohydrates by Nuclear Magnetic -- Chapter 13 Glycobioinformatics -- Chapter 14 Concluding Remarks. .
    Abstract: The growing importance of glycobiology and carbohydrate chemistry in modern biotechnology and the pharmaceutical industry makes accurate carbohydrate analysis indispensable. This book provides the principles and protocols of various fundamental carbohydrate analysis methods. Choice of method is entirely dependent upon the type of material being investigated (biological samples, food products, etc.), and the level of structural detail required, i.e. sugar content, compositional analysis, linkages between the sugar components, or the total chemical structure of a given molecule. Full structural characterization of carbohydrate chains requires significant time, resources, and skill in several methods of analysis; no single technique can address all glycan analysis needs. This book summarizes several existing analytical techniques (both chemical and physical) in an introductory volume designed for the non-expert researcher or novice scientist. While background in carbohydrate chemistry is assumed, all information necessary to understanding the described techniques is addressed in the text.
    Type of Medium: Online Resource
    Pages: XXV, 350 p. 117 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030777913
    Series Statement: Techniques in Life Science and Biomedicine for the Non-Expert,
    URL: https://doi.org/10.1007/978-3-030-77791-3
    DOI: 10.1007/978-3-030-77791-3
    DDC: 615
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  • 18
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    Online Resource
    Polypharmacology : Principles and Methodologies (2022)
    Cham :Springer International Publishing :
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    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Drug delivery systems. ; Neuropharmacology. ; Pharmacology. ; Pharmaceutics. ; Drug Delivery. ; Neuropharmacology.
    Description / Table of Contents: PART I. Polypharmacology as a New Branch of Pharmacology: Concept and Principles -- Basics of Polypharmacology -- Polypharmacology in Clinical Applications: Multitarget Multidrug-combination (MTMD-C) -- Polypharmacology in Clinical Applications: Multitarget Multidrug-single-formulation (MTMD-SF) -- Polypharmacology in Clinical Applications: Multitarget Single-drug (MTSD) -- Polypharmacology in Drug Discovery: Designed Epigenetic MTSD and Small-molecule MTSD -- Anti-cancer Polypharmacology -- Cardiovascular Polypharmacology -- Neuronal Polypharmacology -- Pulmonary Polypharmacology -- Polypharmacology of Metabolic Disease -- Polypharmacology of Infectious Disease -- Polypharmacology of Inflammation -- Anti-psychotics Polypharmacology -- Anti-aging Polypharmacology -- Polypharmacology in Drug Repurposing -- Polypharmacology and Unintended Drug Promiscuity -- Polypharmacology Pharmacokinetics -- The Future of Polypharmacology -- PART II. Polypharmacology in New Drug Development: Strategies and Protocols -- Designed MTSD Discovery Process -- Designed MTSD Discovery Strategies -- Designed MTSD Discovery Technologies -- Designed MTSD Discovery Databases -- Designed MTSD Target Deconvolution.-Designed MTSD Target Validation -- Designed MTSD Lead Identification and Optimization -- Designed MTSD Discovery Protocols -- Natural Products in MTSD Discovery -- Polypharmacology Procedures for Drug Repurposing -- Polypharmacology Procedures for Drug Promiscuity Discovery.
    Abstract: There is a growing interest in unmet needs for the development of a new discipline in drug discovery and in university education on Polypharmacology. However, there has not been a book with the comprehensive compilation of basic knowledge and advanced methodology on Polypharmacology. This book aims to meet the needs of making Polypharmacology a new sub-discipline of Pharmacology, not only being a hot area of pharmacological research and education but also a new paradigm for drug discovery. It contains the contents covering the entire scope of Polypharmacology including systemic in-depth exposition of basic knowledge, novel concepts, innovative technologies, and translational and clinical applications by showcasing state-of-the-art strategies and step-by-step instructions of cutting-edge methods. The contents of Polypharmacology targets broad readerships including scientists in pharmacology research and drug development, and university teachers and graduates in medical school or school of pharmacy. Rich in illustrations and tables to showcase readers for better understanding the concepts and technologies related to Polypharmacology; Provides comprehensive, systemic, holistic, and explicit explanations and discussion of the fundamental knowledge, background information, conceptual evolution, and updated methodology, as well as in-depth mechanisms behind the knowledge and methodology of Polypharmacology; Main emphasis on rationally designed Polypharmacology or “multi-target, single-drug (MTD)” pharmacology, which represents the major future direction of Polypharmacology and Pharmacology; Describes the clinical applications of Polypharmacology to various human diseases in the clinical and preclinical settings; Contains a wide collection of the state-of-the-art Polypharmacology technologies applicable to the designed MTD discovery and the step-by-step descriptions of drug discovery process applying Polypharmacology principles and methodologies.
    Type of Medium: Online Resource
    Pages: XXV, 856 p. 12 illus., 9 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031049989
    URL: https://doi.org/10.1007/978-3-031-04998-9
    DOI: 10.1007/978-3-031-04998-9
    DDC: 615
    Language: English
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  • 19
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    Online Resource
    Advanced Drug Delivery Strategies for Targeting Chronic Inflammatory Lung Diseases (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Nanobiotechnology. ; Biomedical engineering. ; Drug delivery systems. ; Pharmaceutical chemistry. ; Pharmacology. ; Nanobiotechnology. ; Biomedical Engineering and Bioengineering. ; Drug Delivery. ; Pharmaceutics.
    Description / Table of Contents: Chapter 1. An introduction to respiratory diseases and an emerging need for efficient drug delivery systems -- Chapter 2. Inflammatory respiratory diseases: Correlation between Lung cancer and CoVid-19 -- Chapter 3. Advancements in translational respiratory research using nanotechnology -- Chapter 4. Chemical moieties as advanced therapeutics for targeting respiratory disorders -- Chapter 5. Phytochemicals and their nanoformulations targeted for pulmonary diseases -- Chapter 6. Nanocarriers: an advanced and highly effective approach for targeting chronic lung diseases -- Chapter 7. Vesicular drug delivery systems in respiratory diseases -- Chapter 8. Nanoparticles in chronic respiratory diseases -- Chapter 9. Applications of nanotechnology in pulmonary disease diagnosis -- Chapter 10. Nanotechnology in pulmonary disease diagnosis -- Chapter 11. Recent trends in Nanomedicine for diagnosis and treatment of pulmonary diseases -- Chapter 12. Strategies for enhanced drug targeting to inflamed lungs: Novel perspectives -- Chapter 13. Solid-Lipid Nanocarriers (SLN’s) based drug delivery for treating various pulmonary diseases -- Chapter 14. Microparticles, microspheres and microemulsions as pulmonary drug delivery systems for the treatment of respiratory diseases -- Chapter 15. Microparticles, microspheres and microemulsions in respiratory diseases -- Chapter 16. Advanced drug delivery systems targeting the immune system at cellular level in chronic respiratory diseases -- Chapter 17. Targeted Micellar Systems for Pulmonary Disease Intervention -- Chapter 18. Polymeric and inorganic nanoparticles targeting chronic respiratory diseases -- Chapter 19. Mucoadhesive drug delivery system in chronic respiratory diseases -- Chapter 20. Liposomal Drug Delivery: Therapeutic Applications in Chronic Respiratory Diseases -- Chapter 21. Biologics and vaccines for nasal and pulmonary drug delivery -- Chapter 22. Drug delivery systems for respiratory infections -- Chapter 23. Cell and Gene Therapies for Chronic Inflammatory Lung Diseases - Emerging Technological Trends and Advancements in Respiratory Medicine -- Chapter 24. Targeting biofilms in respiratory diseases using novel drug delivery systems -- Chapter 25. Advanced nanomaterials for drug delivery in chronic respiratory disorders -- Chapter 26. Emerging technological trends and advancements in respiratory medicine -- Chapter 27. Pulmonary pharmacokinetics and Biophysics -- Chapter 28. Clinical trials on novel advanced drugs for chronic respiratory disorders.
    Abstract: This book describes the growing clinical and healthcare relevance of nano-therapeutics in treating respiratory diseases. It begins with a brief introduction on the different types of nanoparticles in respiratory disease conditions. It further discusses the current trends in understanding the disease pathology using different in vitro and in vivo models, which are important towards the onsite clinical applications and development of new therapeutics. The book includes exciting topics such as formulation of these nanoparticles, targeting various organelles etc. It also describes the future prospects and challenges in the field. Different chapters are written by researchers actively working in the area of pulmonary diseases. This book is designed to address the requirements of both beginners and specialized scientists involved in pulmonary research. The contents include basic concepts followed by advanced state-of-art monitoring and treatment of diseases. The book is meant for researchers and industry experts in nanotechnology, pharmaceutical sciences and drug design.
    Type of Medium: Online Resource
    Pages: X, 655 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811643927
    URL: https://doi.org/10.1007/978-981-16-4392-7
    DOI: 10.1007/978-981-16-4392-7
    DDC: 615
    Language: English
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  • 20
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    Online Resource
    Data Monitoring Committees (DMCs) : Past, Present, and Future (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Medical sciences. ; Drug development. ; Medicine Research. ; Biology Research. ; Pharmaceutical chemistry. ; Biometry. ; Toxicology. ; Pharmacology. ; Preclinical Research. ; Biomedical Research. ; Pharmaceutics. ; Biostatistics. ; Medical Toxicology.
    Description / Table of Contents: Introduction-.What is a DMC?-. Is a DMC required?-. Who is On the DMC?-. What are the Legal and Ethical Aspects of DMC?-. How does the DMC work with SDAC and Sponsor and External Groups ? -- What Does a DMC Meeting Look Like -- What data is used for DMC outputs and who programs? -- What is Included in DMC Outputs? -- What does the DMC final DMC outputs look like and how is it delivered? -- What Types of Safety Outputs Does the DMC Receive? -- What types of efficacy outputs does the DMC receive? -- What types of other outputs does the DMC receive? -- What About In-Between DMC Meetings -- What types of formal interim analyses does the DMC review? -- What does the paperwork from meetings look like? -- How does the DMC assess risk-benefit for their decision making? -- What are some examples? -- Conclusions.
    Abstract: This book provides an overview of Data Monitoring Committees - what was done in the past, what is currently being done, and thoughts on improvements for the future. Previous works focused primarily on large cardiovascular studies (where DMCs originated more than 30 years ago) but updated references are needed that discuss smaller, more flexible studies in areas such as oncology. The authors have attended ~800 DMC meetings from ~200 distinct studies across all areas of clinical studies (oncology, rheumatology, rare diseases, cardiology, immunology, etc.) This wide range of expertise will be used, as well as the expertise that comes from working with virtually every large biotech/pharma and CRO for DMC work. The reader of the book will know when DMCs are needed or helpful, how to form the DMC, how to work with external CROs and with sponsor teams and the DMC to create needed DMC outputs, how the DMC meetings are conducted, and - especially for DMC members - what are considerations within the Closed Session to review safety/efficacy outputs to assess risk/benefit to make appropriate recommendations that protect the patient safety and trial integrity. This is a practical hands-on book on how to decide if a DMC is necessary, how to form the DMC, how to smoothly create the necessary materials for the DMC and have smooth running DMC meetings. There is no specialized training in school about how DMCs work - frequently people may have been in industry for many years without ever needing to work with a DMC. This book is the helpful reference for those new to these DMCs. The DMC work is critical to be correctly implemented as the implications of it are so great. This book provides the following: Thorough instructions on the steps needed to form and implement a Data Monitoring Committee for clinical trial evaluation; Includes practical and hands-on information on DMC implementation; Discusses a wide range of clinical trial – by phase and therapeutic area.
    Type of Medium: Online Resource
    Pages: XII, 111 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031287602
    URL: https://doi.org/10.1007/978-3-031-28760-2
    DOI: 10.1007/978-3-031-28760-2
    DDC: 615
    Language: English
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  • 21
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    Macrophage Targeted Delivery Systems : Basic Concepts and Therapeutic Applications (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Cytology. ; Toxicology. ; Immunology. ; Pharmacology. ; Pharmaceutics. ; Cell Biology. ; Toxicology. ; Immunology.
    Description / Table of Contents: Part I Anatomy, Physiology and Pharmacology of Macrophages -- Introduction to Anatomy and Physiology of Macrophages from Drug Delivery Perspective -- Introduction to Pharmacology of Macrophages from Drug Delivery Perspective -- Mechanisms and Ways of Macrophage Delivery -- Macrophage Associated Disorders: Pathophysiology, Treatment Challenges and Possible Solutions -- Understanding Macrophage Associated Diseases and Applications of Nano Drug Delivery Systems -- Part II Polymeric Nanoparticles for Macrophage Targeting -- Targeting of Macrophages: Basic and therapeutic Role of Polymeric Nanoparticles -- Polymeric Nanoparticles Based Drug and Gene Delivery to Macrophages -- Surface Modification of Nanoparticles for Macrophage Targeting -- Part III Lipid Nanoparticles for Macrophage Targeting -- Liposomes as Delivery System for Macrophage Targeting -- Solid Lipid Nanoparticles Based Drug and Gene Delivery to Macrophages -- In vivo Fate of Colloidal Carriers Undergoing Macrophage Targeting -- Nanoparticle-based Theranostics for Macrophage-associated Diseases -- Part IV Targeting Macrophages for Treatment of Various Diseases -- Tumor Associated Macrophages as Therapeutic Target for Drug/immune Therapy of Cancer -- Macrophage Targeting for Therapy of Autoimmune Diseases -- Macrophage Targeting for Therapy of Cardiovascular Diseases (CVD) -- Macrophage targeting for therapy of intracellular infections -- Targeting Drugs and Nucleic Acids to Macrophages for Therapy of Inflammatory Diseases -- Macrophage Targeted Chemotherapy for Tuberculosis and other Respiratory Disease. -- Part V Specific Formulations and Clinical Trials on Macrophage Targeted Delivery -- Nano- and Microparticles Based Dry Powder Inhalers for Pulmonary Macrophage Drug Delivery -- Recent Trends in Clinical Studies on Macrophage Targeted Delivery -- Future Directions and Challenges in Macrophage Targeting. .
    Abstract: The proposed book is envisioned for the nascent and entry-level researchers who are interested to work in the field of drug delivery and its applications specifically for macrophage targeting. Macrophages have gained substantial attention as therapeutic targets for drug delivery considering their major role in health and regulation of diseases. Macrophage-targeted therapeutics have now added significant value to the lives and quality of life of patients, without undue adverse effects in multiple disease settings. We anticipate examining and integrating the role of macrophages in the instigation and advancement of various diseases. The major focus of the book is on recent advancements in various targeting strategies using delivery systems or nanocarriers followed by application of these nanocarriers for the treatment of macrophage associated disorders. Macrophage Targeted Delivery Systems is primarily targeted to Pharmaceutical Industry & Academia, Medical & Pharmaceutical Professionals, Undergraduate & Post graduate students and Research Scholars, Ph.D, post docs working in the field of medical and pharmaceutical sciences.
    Type of Medium: Online Resource
    Pages: XVIII, 556 p. 76 illus., 73 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030841645
    URL: https://doi.org/10.1007/978-3-030-84164-5
    DOI: 10.1007/978-3-030-84164-5
    DDC: 615
    Language: English
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  • 22
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    Online Resource
    Synbiotics for the Management of Cancer (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Cancer. ; Cancer Treatment. ; Pharmacology. ; Cancers. ; Cancer Therapy.
    Description / Table of Contents: Chapter 1_Introduction to Cancer -- Chapter 2_Effect of anticancer treatment approches on gut microbiota -- Chapter 3_Synbiotic: A promising approach for the treatment of cancer -- Chapter 4_Correlation between ROS and Synbiotics for effective treatment of cancer -- Chapter 5_Influence of synbiotics on inflammation and immune microenvironment for the treatment of cancer -- Chapter 6_Synbiotics in colorectal cancer -- Chapter 7_Synbiotics in cervical cancer -- Chapter 8_Synbiotics in prostate cancer -- Chapter 9_Synbiotics in gastric cancer -- Chapter 10_Synbiotics in lung cancer -- Chapter 11_Synbiotics in small cell pancretatic cancer -- Chapter 12_Synbiotics in breast cancer -- Chapter 13_Synbiotics in hepatocellular carcinoma -- Chapter 14_Synbiotics in ovarian cancer -- Chapter 15_Regulatory issues of synbiotics in cancer.
    Abstract: This book illustrates the significance of probiotics and prebiotics for the management of various types of cancers. The up-to-date chapters provide recent information about the effect of anticancer treatment approaches on gut microbiota, the correlation between ROS and synbiotics for effective cancer treatment, and the influence of synbiotics on inflammation and immune microenvironment for cancer treatment. It also describes the regulatory issues about synbiotics in the management of cancer. This book is an essential resource for scientists working in the field of cancer, pharmaceutical & clinical sciences, and cancer clinicians. This book is also very useful for undergraduate and postgraduate students of Pharmacy and Biotechnology and medical researchers, mainly working in microbiology, immunology, and cancer biology.
    Type of Medium: Online Resource
    Pages: XVII, 340 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811975509
    URL: https://doi.org/10.1007/978-981-19-7550-9
    DOI: 10.1007/978-981-19-7550-9
    DDC: 615
    Language: English
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  • 23
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    Online Resource
    Recent Advances in Pharmaceutical Innovation and Research (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Drug delivery systems. ; Nanobiotechnology. ; Pharmacology. ; Pharmaceutics. ; Drug Delivery. ; Nanobiotechnology.
    Description / Table of Contents: Part 1. Pharmaceutical Innovation and Research -- Chapter 1. Innovation in stabilization of biopharmaceuticals -- Chapter 2. Concepts in pharmacogenomics: tools and applications -- Chapter 3. Pharmacogenetics–a new approach for the selection of the right drug -- Chapter 4. Meeting the unmet challenges of pharmaceutical research using artificial intelligence -- Chapter 5. Pharmaceutical innovation and research in ayurved -- Chapter 6. Ayurveda intervention in perimenopausal syndrome -- Part 2. Drug Discovery and Development -- Chapter 7. Innovative strategies in drug discovery and pharmacoinformatics -- Chapter 8. Advances in peptide synthesis -- Chapter 9. Peptidomimetics in Medicinal Chemistry: The Art of Transforming Peptides to Drugs -- Chapter 10. Diverse Pharmacological Activities of 4-aminoquinoline and its Derivatives -- Chapter 11. Thiourea catalysts for synthesis of active pharmaceutical ingredients -- Chapter 12. The Chemistry and Pharmacology of Mandarin Orange -- Chapter 13. Recent progress in the pharmacology of phytoestrogens: emerging neuromodulators for treating anxiety and depression -- Chapter 14. Next-generation cell-based therapies to combat metastaticbrain tumor -- Chapter 15. Pharmacokinetics and Pharmacodynamics: Fundamentals and Role(s) in Drug Discovery and Development -- Chapter 16. An update on pharmacokinetic models -- Chapter 17. Pharmacodynamics: Basics and Applications in Drug Research -- Part 3. Drug Delivery and Nanotechnology -- Chapter 18. Technological innovations in pharmaceutical drug nanocrystals -- Chapter 19. Fixed Dose Combinations: Innovations and Research -- Chapter 20. Significance of Intranasal Drug Delivery Systems: Recent Trends and Clinical Investigations in Brain Disorders -- Chapter 21. Current challenges and nanotechnology-based pharmaceutical approaches for the treatment and control of visceral leishmaniasis -- Chapter 22. Polymeric Nanoparticles-based Drug Delivery Systems for Anticancer Therapy. Chapter 23. Carbon nanotubes: a review of toxicity and applicability in biomedical applications -- Chapter 24. Recent trends in topical herbal nanotherapeutics for psoriasis -- Part 4. Pharmaceutical Microbiology -- Chapter 25. Antibiotics: past, present, future, and clinical pipeline -- Chapter 26. Innovative strategies to tackle antimicrobial resistance -- Chapter 27. Molecular and mechanistic insights of yeast flocculation -- Chapter 28. Management of hepatitis virus C: current and future treatments -- Chapter 29. Tuberculosis: experimental models, innovations and challenges -- Chapter 30. Targeting outer membrane to tackle multi-drug resistant bacterial pathogens -- Chapter 31. Diphtheria-A Paradigmatic Vaccine Preventable Toxigenic Disease with Changing Epidemiology -- Chapter 32. Emerging and re-emerging infections: an overview.
    Abstract: This book covers several important aspects of pharmaceutical research and innovations. It presents important topics on drug delivery, novel microsponge, nanocrystals, polymeric nanoparticles, peptide synthesis, biopharmaceuticals, pharmacodynamics, yeast flocculation, neuromodulators, innovative drug discovery, pharmacoinformatics, aminoquinoline, thiourea crystals for API synthesis, FDCs and formulations research, ayurveda and natural products, and innovations to militate anti-microbial resistance (AMR). A chapter is devoted to the applications of Artificial Intelligence and Machine Learning in diverse sectors of the pharmaceutical industry, including drug discovery and development, drug repurposing, and improving pharmaceutical productivity. The book also reviews the role of pharmacogenomics and pharmacogenetics in drug development and precision medicine. Further, the book presents an updated summary of recent advances in the fields of nanomedicines and nano-based drug delivery systems. This book is useful to pharmaceutical sciences students, researchers, educators, and professionals in the pharmaceutical industry to understand the intricacies of new drug research and innovations.
    Type of Medium: Online Resource
    Pages: XXI, 770 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819923021
    URL: https://doi.org/10.1007/978-981-99-2302-1
    DOI: 10.1007/978-981-99-2302-1
    DDC: 615
    Language: English
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  • 24
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    Online Resource
    Block Co-polymeric Nanocarriers: Design, Concept, and Therapeutic Applications (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Nanobiotechnology. ; Drug delivery systems. ; Pharmacology. ; Nanobiotechnology. ; Drug Delivery.
    Description / Table of Contents: Ch 1 Introduction to block co-polymers -- Ch 2 Role of block co-polymers in drug delivery -- Ch 3 Role of block co-polymers in enhancement of poor solubility of drugs -- Ch 4 Synthesis and Self–assembly of block copolymers -- Ch 5 Role of block co-polymers in treatment of brain disorders -- Ch 6 Role of block co-polymers in treatment of neurodegenerative disorders -- Ch 7 Role of block co-polymers in colon cancer -- Ch 8 Role of block co-polymers in lung cancer -- Ch 9 Role of block co-polymers in IBD -- Ch 10 Role of block co-polymers in vaccine -- Ch 11 Role of block co-polymers in treatment of GIT disorders -- Ch 12 Role of block co-polymers in topical drug delivery -- Ch 13 Role of block co-polymers in targeted drug delivery -- Ch 14 Role of block co-polymers in ocular drug delivery -- Ch 15 Role of block co-polymeric micelles in drug delivery -- Ch 16 Applications of block co-polymers as Stimuli Responsive Copolymers -- Ch 17 Patented block co-polymers for various Therapeutics Applications.
    Abstract: This book focuses on current advancements in the field of block copolymers and covers design, concept, and various therapeutic applications in the drug delivery. It also reviews the use of block copolymers in drug delivery applications from the development of sustained release products to smart polymeric delivery systems such as stimuli-responsive polymeric systems, for example, thermosensitive, redox-sensitive, photo-sensitive, and enzyme-sensitive. The book further discusses the nano assemblies from amphiphilic block copolymers as nanomedicine platforms for diagnosis and therapy due to their relatively small size, high drug loading capacity, controlled drug release, in vivo stability, and prolonged blood circulation. The chapters also review the various patents and ongoing clinical trials on the applications, covering several important new concepts and findings in the field of block copolymers. The book is aimed at researchers, academicians, and industrial scientists involved in the development of drug-delivery systems based on polymers.
    Type of Medium: Online Resource
    Pages: XVII, 429 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819969173
    URL: https://doi.org/10.1007/978-981-99-6917-3
    DOI: 10.1007/978-981-99-6917-3
    DDC: 615
    Language: English
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  • 25
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    Online Resource
    Pharmacology of Immunotherapeutic Drugs (2020)
    Cham :Springer International Publishing :
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    Keywords: Pharmacology. ; Immunology. ; Pharmacology. ; Immunology.
    Description / Table of Contents: Preface Chapter 1: Overview of the Immune System and its Pharmacological Targets -- Chapter 2: Modulation of the Innate Immune System -- Chapter 3: Modulation of the Adaptive Immune System -- Chapter 4: Respiratory Disorders of the Immune System and their Pharmacological Treatment -- Chapter 5: Inflammation of the Skin and its therapeutic topics -- Chapter 6: Inflammatory Diseases of the Gastrointestinal Tract and Pharmacological Treatments -- Chapter 7: Mechanisms of Autoimmunity and Pharmacologic Treatments -- Chapter 8: Transplantation: Immunologic Principles and Pharmacologic Agents -- Chapter 9: Immunopathogenesis, Immunization, and Treatment of Infectious Diseases -- Chapter 10: Cancer Immunotherapy.
    Abstract: Medicine has entered a golden age in which therapeutic agents are becoming widely available due to advances in basic science and technology. As such, many drugs have been developed that target inflammatory processes and/or the immune system. This book is intended for health professionals examining the modulation of inflammation by immunotherapeutic drugs. The immune system fills the primordial role of host defense and resistance to infections with pathogenic microorganisms. Several hematopoietic-derived cells constituting the innate and adaptive immune systems cooperate to provide barriers for microbial colonization and/or promote pathogen destruction within the host. Conversely, many immune cells are also involved in the pathogenesis and propagation of chronic inflammatory diseases. The beginning of this book details various components of the immune system including the cell types, lymphoid tissues, soluble cytokines and surface molecules that are essential for host defense. Breakdowns in immune tolerance, or dysregulated immune responses to antigens derived from self tissues or innocuous sources, can lead to the development of autoimmunity or chronic inflammatory diseases. Pathophysiologic roles for the immune system are detailed in corresponding chapters on autoimmunity, epithelial surfaces (lungs, skin, intestine), and transplantation, with special emphasis placed on immunotherapeutic drug targets. The last section of the book focuses on treatments that stimulate our immune system to specifically target and fight infectious diseases and cancer. In each chapter, the medications used to treat various diseases/conditions in terms of their mechanism of action and other pharmacologic properties are discussed in detail. Chapters begin with a table showing drug names and classifications. The importance of basic science and clinical trials cannot be understated in the context of drug development. As such, the discovery of certain medications that had a lasting impact in medicine and pharmacy are highlighted in chapter subsections named “Bench to Bedside.” Several clinical applications of immunotherapeutic drugs are described within end-of -chapter case studies including practice questions. The Pharmacology of Immunotherapeutic Drugs is a reference for immunologists and clinicians (medical doctors, pharmacists, nurses) examining the modulation of inflammatory processes by a variety of medications targeting the cells and mediators of our immune system.
    Type of Medium: Online Resource
    Pages: XIX, 399 p. 118 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030199227
    URL: https://doi.org/10.1007/978-3-030-19922-7
    DOI: 10.1007/978-3-030-19922-7
    DDC: 615
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  • 26
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    Online Resource
    Biomedical Applications and Toxicity of Nanomaterials (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Nanobiotechnology. ; Nanomedicine. ; Pharmacology. ; Nanobiotechnology. ; Nanomedicine and Nanotoxicology.
    Description / Table of Contents: Chapter 1. Macroporous cryogel-based systems for water treatment applications and Safety: nanocomposite-based cryogels and bacteria-based bioreactors -- Chapter 2. One dimensional Semiconducting Nanomaterials: Toxicity and Clinical Applications -- Chapter 3. Prospects of Safe use of Nanomaterials in Biomedicalapplications -- Chapter 4. Hyaluronic acid-based nanotechnologies for delivery and treatment -- Chapter 5. Theranostics nanomaterials for safe cancer treatment -- Chapter 6. Cardiovascular safety assessment of new chemical entities: current perspective and emerging technologies -- Chapter 7. Toxicology of pharmaceutical products during drug development -- Chapter 8. Safety and Risk assessment of food items -- Chapter 9. Non toxic Natural products as regulators of tumour suppressor gene function -- Chapter 10. Advancements in the safety of Plant medicine: Back to nature -- Chapter 11. Chemicals and their interaction in the aquaculture system -- Chapter 12. Zebrafish as a biomedical model to define developmental origins of chemical toxicity -- Chapter 13. Green synthesis of non toxic nanoparticles -- Chapter 14. Synthesis, characterisation and safety of titanium oxide nanoparticles -- Chapter 15. Characterisation of non toxic nanomaterials for biological applications -- Chapter 16. Toxicity assessment of nanoparticle -- Chapter 17. Safety of nanoparticles: emphasis on antimicrobial properties -- Chapter 18. Quantum dots for imaging and its safety -- Chapter 19. Genotoxicity evaluation of nanosized materia -- Chapter 20. Scaffoldmaterials and toxicity -- Chapter 21 Biological Safety and Cellular interactions of nanoparticles -- Chapter 22. Role of artificial intelligence in the toxicity prediction of drugs -- Chapter 23. Chemicals and rodent models for the safety study of alzheimer’s disease -- Chapter 24. Mitochondria-targeted liposomal delivery in Parkinson's disease: safety concerns -- Chapter 25. Routes of Nano-drug Administration and Nano-based drug delivery system and toxicity -- Chapter 26. Green Synthesised silver nanoparticles phytotoxicity and applications in agriculture: An overview -- Chapter 27 status of safety concerns of microplastic detection strategies -- Chapter 28. Impact of insecticides on man and environment.
    Abstract: This book covers the recent trends on the biological applications of nanomaterials, methods for their preparation, and techniques for their characterization. Further, the book examines the fundamentals of nanotoxicity, methods to assess the toxicity of engineered nanomaterials, approaches to reduce toxicity during synthesis. It also provides an overview of the state of the art in the application of Artificial intelligence-based methodologies for evaluation of toxicity of drugs and nanoparticles. The book further discusses nanocarrier design, routes of various nanoparticle administration, nano based drug delivery systems, and the toxicity challenges associated with each drug delivery method. It presents the latest advances in the interaction of nanoparticles with the cellular environment and assess nanotoxicity of these engineered nanoparticles. The book also explores the comparative and mechanistic genotoxicity assessment of the nanomaterials. This book is useful source of information for industrial practitioners, policy makers, and other professionals in the fields of toxicology, medicine, pharmacology, food, and drugs.
    Type of Medium: Online Resource
    Pages: XVIII, 768 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811978340
    URL: https://doi.org/10.1007/978-981-19-7834-0
    DOI: 10.1007/978-981-19-7834-0
    DDC: 615
    Language: English
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  • 27
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    Online Resource
    Pharmacology of Drug Stereoisomers (2022)
    Singapore :Springer Nature Singapore :
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    Keywords: Pharmacology. ; Medicinal chemistry. ; Pharmaceutical chemistry. ; Biotechnology. ; Biochemical engineering. ; Pharmacology. ; Medicinal Chemistry. ; Pharmaceutics. ; Biotechnology. ; Bioprocess Engineering.
    Description / Table of Contents: Preface -- General principles of chirality -- Quantitative methods of analysing chirality drugs - Chirality and pharmacokinetics -- Drugs regulating the function of peripheral nervous system -- In silico search for chiral drug compounds.
    Abstract: The book is devoted to an important aspect of pharmacology and pharmaceutical chemistry, i.e. the significance of stereoisomerism of drugs for their biological effect from the point of view of their pharmacokinetics, pharmacodynamics and toxicology. The authors review the landmarks in the development of stereochemistry and stereopharmacology. Present-day IUPAC terminology is discussed; general issues of stereoisomerism are considered including separation of racemic mixtures and asymmetric synthesis of isomers, methods of quantifying the isomers of a drug in biological material. The authors put special emphasis on general problems of the influence of stereoisomerism on pharmacological and adverse effects of drugs. A classification of drugs based on stereochemical properties of their isomers is proposed. Possibilities of interaction of stereoisomers in racemic mixtures are discussed. A considerable portion of the book is devoted to pharmacological action of the main groups of drugs whose structure includes asymmetric atoms (that is, drugs with several isomers). Detailed attention is paid to advisability of developing single isomer drugs and to the specifics of their study at the stage of preclinical and clinical trials.
    Type of Medium: Online Resource
    Pages: XI, 207 p. 174 illus., 6 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811923203
    Series Statement: Progress in Drug Research, 76
    URL: https://doi.org/10.1007/978-981-19-2320-3
    DOI: 10.1007/978-981-19-2320-3
    DDC: 615
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  • 28
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    Online Resource
    Rabies and Rabies Vaccines (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Virology. ; Immunology. ; Pharmacology. ; Virology. ; Immunology.
    Description / Table of Contents: Rabies Life Cycle, Transmission and Pathogenesis -- History of Rabies and Rabies Vaccines -- Rabies vaccines for wildlife -- Human Rabies Vaccines -- Rabies vaccines, prophylactic, Peru -- Rabies Prevention in Asia: Institutionalizing Implementation Capacities -- Passive Immunity in Rabies Prophylaxis -- Rabies Little Virus Against Powerful Innate Immunity -- Novel Rabies Vaccines -- Assessing the potency of inactivated veterinary vaccines and oral live vaccines against rabies -- WHO Perspective on Rabies.
    Abstract: This book reviews the recent advances in rabies research and rabies vaccine development. The reader is introduced to biology and pathology of the virus, causing agents and the history of rabies vaccination. The book presents regional rabies prophylaxis programs and discusses vaccination strategies for wildlife and humans. Further, innate immune response as well as antibody response to rabies are examined. All chapters are written by renowned experts in rabies research, some of them part of the WHO Collaboration Centre for Rabies Surveillance and Research. The book targets researchers and health professionals working in Virology, Veterinary Medicine and Biomedicine. .
    Type of Medium: Online Resource
    Pages: VII, 205 p. 15 illus., 12 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030210847
    URL: https://doi.org/10.1007/978-3-030-21084-7
    DOI: 10.1007/978-3-030-21084-7
    DDC: 615
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  • 29
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    Online Resource
    Principles of Forensic Toxicology (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Forensic sciences. ; Medical jurisprudence. ; Pharmacology. ; Forensic Science. ; Forensic Medicine.
    Description / Table of Contents: Part 1: Introduction -- Post Mortem Forensic Toxicology -- Human Performance Toxicology -- Drug-Facilitated Sexual Assault -- Forensic Drug Testing -- Performance enhancing Drug Testing -- Drug Testing in Pain Management -- Pharmacokinetics and Pharmacodynamics -- Part II. Specimen Preparation -- Spectrophotometry -- Chromatography -- Derivatization -- Immunoassy -- Mass Spectrometry -- Quantitation -- Method Validation -- Measurement Uncertainty and Traceability -- Statistics in Forensic Toxicology -- Part III Analytes -- Alcohol -- Benzodiazapines -- Gammahydroxybutyric acid,- Miscellaneous Central Nervous System Depressants -- Opioids -- Cocanie -- Cannabis -- Amphetamines-Sympathomimetic Amines,- Hallucinogens and Psychedelics -- Antidepressants and Neuroleptics -- Miscellaneous Therapeutic Drugs -- Carbon Monoxide/Cyanide -- Inhalants -- Metals -- Part III Special Topics -- Stability of Drugs of Abuse in Biological Systems -- Postmortem Redistribution of Drugs -- Postmortem Clinical Testing -- Pharmacogenomics -- Hair Drug Testing -- Oral Fluid Testing -- Meconium Drug Testing -- Drugs in Embalmed Tissues.
    Abstract: The fifth edition of the best-selling Principles in Forensic Toxicology continues in the tradition of excellence in academic publishing. With over 10 years of classroom-tested and continually updated content, the new edition contains significant updates and 7 new chapters on new topics including drug-facilitated crimes, derivatization, quantitation, measurement uncertainty/traceability, statistics, oral fluid testing, and drugs in embalmed specimens. Part One covers the major sub-disciplines of forensic toxicology in addition to pharmacological concepts. Part Two addresses specimen preparation, laboratory testing and instrumental analysis, while Part Three discusses common analytes including cocaine, opioids, alcohol, and marijuana. Adopted for courses in many of the top universities for forensic science and used by respected medical examiner’s offices and crime laboratories worldwide, Principles of Forensic Toxicology prepares the next generation of forensic toxicologists and continues to be an important reference in professional practice.
    Type of Medium: Online Resource
    Pages: XIII, 691 p. 188 illus., 23 illus. in color. , online resource.
    Edition: 5th ed. 2020.
    ISBN: 9783030429171
    URL: https://doi.org/10.1007/978-3-030-42917-1
    DOI: 10.1007/978-3-030-42917-1
    DDC: 615
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  • 30
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    Online Resource
    Recent Advances in Therapeutic Drug Monitoring and Clinical Toxicology (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Toxicology. ; Pharmaceutical chemistry. ; Pharmacology. ; Toxicology. ; Pharmaceutics.
    Description / Table of Contents: Therapeutic and toxic concentration of drugs in biological matrices -- Analytical techniques for therapeutic drug monitoring and clinical toxicology -- Plasma therapeutic drug monitoring and clinical toxicology -- Dried blood spots in therapeutic drug monitoring and toxicology -- The role of artificial intelligence in therapeutic drug monitoring and clinical toxicity -- Therapeutic drug monitoring and optimal pharmacotherapy with medicines of narrow therapeutic index -- Therapeutic drug monitoring (TDM) and toxicological studies in alternative biological matrices -- Analyzing data from therapeutic drug monitoring, pharmacokinetics, and clinical toxicology studies -- Reducing toxicity in critically ill patients by using therapeutic drug monitoring -- Quality assurance of samples for therapeutic drug monitoring and clinical toxicology -- Therapeutic drug monitoring and toxicology of anticancer drugs -- Therapeutic drug monitoring and toxicology of immunosuppressant -- Therapeutic drug monitoring and toxicology: relevance of measuring metabolites -- Recent advances in nanosensors for Therapeutic Drug Monitoring (TDM) -- Organ toxicity by immunosuppressive drugs in solid organ transplantation -- Artificial intelligence-based techniques to assess drug toxicity in drug induced liver injury (DILI) disease -- Drug dose and therapy individualization -- Models for drug individualization: patient to population level -- Toxicity evaluation of nanomedicine -- Biochemical indices of drug toxicity -- Therapeutic drug monitoring and clinical toxicology: challenges and future directions.
    Abstract: This book gives an overview of therapeutic drug monitoring (TDM) and its clinical application. It also highlights recent advances in toxicological studies, as they relate to therapeutic drug monitoring. This is one of the few books available on the market that covers TDM. Therapeutic drug monitoring (TDM) is a clinical decision-making tool that enables dosage regimen adjustments based on clinical and laboratory measurements. TDM not only involves the measuring of drug concentrations but also interpretation of the results. There is a strong correlation between drug concentrations in body fluids and outcome than between dose and outcome. The chapters include coverage of analytical techniques, pharmacokinetics, therapeutic indices, artificial intelligence and recent advances in toxicological studies. The book fills a gap in published literature and provides reliable information on; Analytical techniques in TDM and clinical toxicology TDM and pharmacokinetic studies TDM of drugs with narrow therapeutic indices Artificial intelligence in TDM and clinical toxicology Future directions and challenges .
    Type of Medium: Online Resource
    Pages: XVIII, 381 p. 43 illus., 41 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031123986
    URL: https://doi.org/10.1007/978-3-031-12398-6
    DOI: 10.1007/978-3-031-12398-6
    DDC: 615
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  • 31
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    From PharmD to Industry : A Fellowship Guide (2023)
    Cham :Springer Nature Switzerland :
    Details
    Keywords: Pharmacology. ; Pharmacy. ; Career education. ; Pharmacology. ; Pharmacy. ; Career Skills.
    Description / Table of Contents: Fellowship 101 -- The First Professional Year (P1) -- The Second Professional Year (P2) -- The Third Professional Year (P3) -- The Fourth Professional Year (P4) -- Midyear Applications, Interviews, and Receptions -- Transitioning from Student to Fellow -- Navigating the Virtual Landscape.
    Abstract: For many Doctor of Pharmacy (PharmD) candidates, post-graduate training is a highly prestigious and sought after experience that can further one’s pre-existing education. Some of these post-graduate training opportunities include but are not limited to pharmacy residencies, pharmaceutical industry fellowships, and PhD/Masters programs. There is a large gap in the current Doctor of Pharmacy curriculum about pharmaceutical industry fellowship programs and potential pharmaceutical industry opportunities. Through the eyes of current industry fellows and professionals, this book serves as a resource to learn more about fellowship opportunities and their respective application processes. In addition, this manual aims to provide a clear and concise roadmap to achieving a career in industry through a fellowship program. Whether you are a current student pharmacist, post-graduate pharmacy trainee (pharmacy resident), or industry professional, this manual addresses the current landscape of industry fellowship programs, an overview of industry opportunities, and a glimpse into what being a fellow entails. Readers of this book can expect to gain: An overview of pharmaceutical industry fellowship programs and opportunities Helpful advice and insight from current fellows and industry professionals A streamlined pathway to navigating the fellowship application process An understanding of the journey from being a student, to achieving a fellowship, to becoming an industry professional This book bridges the gap in education surrounding pharmaceutical industry fellowships and pharmacy careers in industry and increases access to first-hand information and real-world perspectives of current professionals to provide a firm foundation for those interested in pursuing a career in industry or learning more about fellowship programs.
    Type of Medium: Online Resource
    Pages: XIX, 92 p. 4 illus., 3 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031357879
    Series Statement: SpringerBriefs in Pharmaceutical Science & Drug Development,
    URL: https://doi.org/10.1007/978-3-031-35787-9
    DOI: 10.1007/978-3-031-35787-9
    DDC: 615
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  • 32
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    Online Resource
    Contract Research and Development Organizations-Their History, Selection, and Utilization (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Pharmacy. ; Pharmacology. ; Pharmacy.
    Description / Table of Contents: Introduction -- History of CROs: Including CRO Snapshots and a CRO Genealogy Chart -- The Pharmaceutical Development Process & Testing Requirements -- The Medical Device Development Process & Testing Requirements -- Functions and Types of CROs -- Labs in China and India -- Selection of CROs -- Study Directors and PIs -- Nuts and Bolts of Study Performance SCG/CBS -- Electronic Reporting Requirements (SEND & eCTD) -- Study and Project Monitoring -- Contracting, Pricing, and Cost of Works Performed by CROs -- Consultants and their Role -- Building Relationships: Maximizing your return on Expectations with a CRO -- Common Problems and their Solutions -- Appendices: A Toxicology Labs B Medical Device Labs C Phase I Labs D Analytical Labs E GMP Contract Facilities F Formulation G Dosage Forms H Clinical Testing I Regulatory Services J Forms and Checklists -- K Specialized Services -- L Consultants Known to be In-Practice -- Index. .
    Abstract: This volume provides a complete update of all the materials in prior volumes on the subject (including current directories to testing labs and other support establishments worldwide), while adding substantial new material on the following topics: · The history of CROs, including snapshots of CROs and a genealogy chart making clear where they came from and where they went. · Study directors and principal investigators. · The nuts and bolts of study performance. · Electronic reporting requirements – SEND and eCTD (required for NDA, BLA, ANDA, and IND submissions). · Consultants and their roles. · An expanded examination of common problems and their solutions. This book boasts complete directories to the global universe of operating labs – where they are, how to contact them, and what they do (including special capabilities). Additionally, checklists for qualifying labs and manufacturing facilities – and for auditing studies and projects at such facilities – are included. It is directed at those in industry (specifically directed at those working for companies using CRO services) but will also be of interest to scientists or administrators working in research organizations themselves. In this case, the contents of this new work are essential to the target reader because the work, regulations, and actors (CROs) have evolved and changed at a rapid pace in the 10 years since the earlier volume that the author published. Likewise, the companies using these services have come to all be almost completely dependent on outsourcing. The earlier texts remain the only source of their kind (paper or electronic) on the field and the only noncommercial guide to the global industry and this volume provides a complete update.
    Type of Medium: Online Resource
    Pages: XIII, 519 p. 19 illus., 1 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030430733
    URL: https://doi.org/10.1007/978-3-030-43073-3
    DOI: 10.1007/978-3-030-43073-3
    DDC: 615
    Language: English
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    Toll-like Receptors in Health and Disease (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Immunology. ; Inflammation. ; Pharmacology. ; Immunology. ; Inflammation.
    Description / Table of Contents: Intracellular TLRs (TLR3, TLR7, and TRL9) in host defense or TLRs in mast cells -- Toll-like receptors as drug targets in the intestinal epithelium -- Innate immune memory-priming, tolerance and exhaustion-in health and disease -- TLRs in brain immunity -- TLRs in cerebrovascular diseases -- TLRs in stem cells or progenitor cells -- TLRs in adaptive immunity -- Overview on TLRs in immunity -- TLR10 and its role in immunity.
    Abstract: The current book is focussed on the Toll-like receptors (TLRs), which are the first pattern recognition receptors (PRRs) discovered in humans. For example, TLR4 was first recognized in humans in 1997 as a PRR recognizing the Gram-negative bacterial lipopolysaccharide (LPS). This discovery revolutionized the field of innate immunity and filled the long-standing gap in the pathogen recognition by the immune system. Now, it is well established that humans have 10 (TLR1-TLR10) and mice have 12 (TLR1-TLR13) functional TLRs, excluding TLR10 that is present as a defective pseudogene. TLRs are present as both membrane-bound extracellular (TLR1, TLR2, TLR4, TLR5, TLR6, and TLR10) and intracellular (TLR3, TLR7, TLR8, and TLR9) PRRs in humans, which identify different pathogen or microbe-associated molecular patterns (PAMPs or MAMPs) and death or damage-associated molecular patterns (DAMPs) released by the host cells. A lot of development in the TLR biology has occurred in last 24 years since there first discovery in humans. The book is intended to describe their role in the host defence, human reproduction, non-infectious sterile inflammatory conditions, including brain immunity and cerebrovascular diseases, signaling mechanisms, adaptive immunity, and their targeting for drug development.
    Type of Medium: Online Resource
    Pages: VIII, 314 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031065125
    Series Statement: Handbook of Experimental Pharmacology, 276
    URL: https://doi.org/10.1007/978-3-031-06512-5
    DOI: 10.1007/978-3-031-06512-5
    DDC: 615
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    Prebiotics, Probiotics and Nutraceuticals (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Clinical medicine Research. ; Medicine Research. ; Biology Research. ; Pharmacology. ; Clinical Research. ; Biomedical Research.
    Description / Table of Contents: Chapter 1. Potentiality of Probiotics in Inactivation of Tetrodotoxin -- Chapter 2. Therapeutic Strategy for the Deterrence of COVID-19 with Relevance to Probiotics -- Chapter 3. Plant based Bioactive compounds in Cancer Therapeutics -- Chapter 4. Therapeutic Strategy for the Deterrence of COVID-19 with Relevance to Probiotics -- Chapter 5. Probiotics as efficacious therapeutic option for treating gut-related diseases: molecular and immunobiological perspectives -- Chapter 6. The progressive development of probiotics, prebiotics, synbiotics research, and its multipurpose use in the ornamental fishery -- Chapter 7. The commercial perspective of probiotics, and bioremediating components in aquaculture pond management: A Case Study -- Chapter 8. Prebiotics as promising therapeutics for treating gut-related disorders : Biochemical and Molecular Perspectives -- Chapter 9. Prebiotics and Probiotics as Functional Foods: Prospect and Promises in Metabolic Diseases. Chapter 10. Implications of probiotics and prebiotics on immune functions -- Chapter 11. Recent Trends in Natural Medicines and Nutraceuticals Research -- Chapter 12. Nutraceuticals-are alternative to modern medicines- Chapter 13. Socio-Economic Study of Prospective of probiotic, prebiotic and synbiotic for sustainable development of aquaculture in Indian Sunderban -- Chapter 14. Drosophila melanogaster as an in-vivo model for the investigation of host microbiota interaction -- Chapter 15. Prospectives of Prebiotics, Probiotics and Synbiotics for Sustainable Development of Aquaculture.
    Abstract: The book titled ‘Prebiotics, Probiotics and Nutraceuticals’ is expected to direct many emerging research pathwaysneed at local and global levels for nutrition and food supplements for developing immunity for healthy life. This volume incorporates sixteen seminal papers on issue based research and their practical applications covering latest information and progress on different area of nutritional supplement research fight against disease. The book highlights the frontier issues and applications in nutritional biotechnology with wide coverage of the themes like Potentiality of Probiotics in Inactivation of Tetrodotoxin, Therapeutic Strategy for the Deterrence of COVID-19 with Relevance to Probiotics and Prospectives of Prebiotics, Probiotics and Synbiotics for Sustainable Development in Aquaculture.Plant based Bioactive compounds in Cancer Therapeutics, Recent Trends in Natural Medicines and Nutraceuticals Research, Probiotics as efficacious therapeutic option for treating gut-related diseases: molecular and immune-biological perspectives, The progressive development of probiotics, prebiotics, synbiotics research, and its multipurpose use in the ornamental fishery, The commercial perspective of probiotics, and bioremediating components in aquaculture pond management: A Case Study andPrebiotics as promising therapeutics for treating gut-related disorders : Biochemical and Molecular Perspectives. Prebiotics and Probiotics as Functional Foods: Prospect and Promises in Metabolic Diseases, Implications of probiotics and prebiotics on immune functions. Recent Trends in Natural Medicines and Nutraceuticals Research, Nutraceuticals are alternative to modern medicines, Socio-Economic Study of Prospective of probiotic, prebiotic and synbiotic for sustainable development of aquaculture in Indian Sunderban. This book will be very useful for the scholars, biotechnologists, agricultural scientists, nutritionist, medical doctors, researchers, teachers and students in the emerging field of biotechnology.
    Type of Medium: Online Resource
    Pages: XVI, 340 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811689901
    URL: https://doi.org/10.1007/978-981-16-8990-1
    DOI: 10.1007/978-981-16-8990-1
    DDC: 615
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    Brazilian Mangroves and Salt Marshes (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Environment. ; Physical geography. ; Conservation biology. ; Ecology . ; Freshwater ecology. ; Marine ecology. ; Environmental Sciences. ; Earth System Sciences. ; Conservation Biology. ; Freshwater and Marine Ecology.
    Description / Table of Contents: Part I - Tropical and Subtropical Brazilian Coastal Zone -- 1. Brazilian Coastal Zone: Mangroves and Salt Marshes -- 2. Zonation and succession of mangrove and salt marsh ecosystems: typical and associated vegetation species -- Part II - The Mangrove Ecosystem -- 3. Variability of Mangroves along the Brazilian Coast -- 4. Ecophysiological and phenology aspects of mangrove species on the Brazilian coast -- 5. Genetic and epigenetic diversity of mangrove plants: markers of adaptation in a changing environment -- 6. A Review on litterfall in Brazilian mangroves -- Part III - The Salt Marsh Ecosystem -- 7. Brazilian salt marshes -- Part IV - The Mangroves and Salt Marshes Associates -- 8. Microbial diversity and microbial food chain -- 9. Brazilian mangrove and salt marsh macroalgal communities -- 10. Invertebrates: Ecology macro and meiofauna associated with mangroves and marshes Brazilian -- 11. Biodiversity, ecology and socioeconomic importance of brachyuran crabs from Brazilian mangroves and salt marshes -- 12. Fish composition in mangroves and salt marshes along the Brazilian coast -- 13. Birds associated with mangroves and salt marshes in Brazil -- 14. Marine mammals and mangroves and mangroves and salt marshes in Brazil: past, present and potencial scenarios -- Part V - Conservation Strategies -- 15. Historical ecology of mangroves: investigating the past to conserve the future -- 16. Economic valuation as a tool for conservation of the Brazilian marine biodiversity of mangrove and salt marsh ecosystems -- 17. Mangrove protected areas in Brazil: controversies and perspectives -- 18. Contributions of environmental education to mangrove conservation -- 19. Magrove and salt marsh ecosystems: what to expect from climate changes -- 20. Coastal zone adaptive management -- Index.
    Abstract: This book offers a new ecosystemic approach to the understanding of mangrove and salt marsh ecosystems. Brazil has one of the largest areas of mangroves in the world, where salt marshes might or might not be associated. Different landscapes comprise the extensive coastline, where mangrove and salt marsh species’ composition is discussed through the analysis of physiography, zonation, and succession processes. Both salt marsh and mangrove plants and the associated macroalgae will be characterized in their ecophysiological and phenological aspects, as well as genetic and epigenetic diversity. The chapters on microbial diversity and litterfall expose the well-known importance of these ecosystems as highly productive carbon sinks and pumps. The associated fauna of invertebrates (benthic meio and macrofaunas, especially brachyuran crabs) and vertebrates (fishes, birds, and mammals) are presented in a special section. The conservational approach encompasses issues, such as historical ecology, economic valuation, protected areas, environmental education, climate changes, and adaptive management.
    Type of Medium: Online Resource
    Pages: XIX, 394 p. 54 illus., 41 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031134869
    Series Statement: Brazilian Marine Biodiversity,
    URL: https://doi.org/10.1007/978-3-031-13486-9
    DOI: 10.1007/978-3-031-13486-9
    DDC: 333.7
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    Botulinum Toxin Treatment in Surgery, Dentistry, and Veterinary Medicine (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Surgery. ; Dentistry. ; Veterinary medicine. ; Neurology . ; Orthopedic surgery. ; Pharmacology. ; Surgery. ; Dentistry. ; Veterinary Science. ; Neurology. ; Surgical Orthopedics.
    Description / Table of Contents: 1. History of development of botulinum toxin therapy in medical and surgical fields -- 2. Molecular structure and mechanisms of action of botulinum toxins as it pertains to clinical symptoms -- 3. Types of toxins in commercial use, their similarities and differences -- 4. A review of current Botulinum toxin treatment indications in medical field. - 5. Mechanisms of Analgesic effects of botulinum neurotoxins -- 6. Botulinum toxin treatment in Head and neck surgery -- 7. Botulinum toxin treatment of thoracic and abdominal surgery -- 8. Botulinum Toxin A in Abdominal Wall Reconstruction -- 9. Use of Botulinum toxin A in post-mastectomy breast reconstruction -- 10. Botulinum Toxins for Treatment of Pain in Orthopedic Disorders -- 11. Botulinum toxin for pediatric patients, Who? For what? When? -- 12. Botulinum Toxin Treatment in Plastic Surgery -- 13. Botulinum Toxin Treatment in Ophthalmology and Ophthalmic surgery -- 14. Botulinum Toxin Treatment in Gastrointestinal Disorders -- 15. Botulinum Toxin Treatment in Urological Disorders -- 16. Botulinum Toxin Treatment in Dentistry -- 17. Botulinum toxin treatment in Veterinary Medicine - Clinical implications -- 18. Future Perspectives of Botulinum Toxin Application In Dentistry.
    Abstract: All books on the market which have been written on the subject of botulinum toxin therapy focus on treatment of hyperactive movement disorders, autonomic dysfunction (bladder, sweat and salivary glands) and some pain indications (migraine). Reference to pre-or post -surgical indications are brief and often out-dated. No book has information on dentistry or veterinary medicine. This book provides up-to-date information on botulinum toxin therapy in surgical fields. It is also the only book in the market that provides information on botulinum toxin therapy in dentistry and veterinary medicine and furnishes the latest information. Botulinum Toxin Treatment in Surgery, Dentistry, and Veterinary Medicine appeals to many disciplines including surgery, dentistry and veterinary medicines well as appealing to neurologists and internists.
    Type of Medium: Online Resource
    Pages: VIII, 398 p. 70 illus., 60 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030506919
    URL: https://doi.org/10.1007/978-3-030-50691-9
    DOI: 10.1007/978-3-030-50691-9
    DDC: 615
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    Metabolomics and Its Impact on Health and Diseases (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Biochemical markers. ; Cytology. ; Analytical biochemistry. ; Pharmacology. ; Biomarkers. ; Cell Biology. ; Analytical Biochemistry.
    Description / Table of Contents: Preface -- Practical Aspects of NMR-Based Metabolomics -- Compound Identification in Mass Spectrometry-Based Metabolomics -- METABOLOMICS USING NMR – Avoiding the ‘Black-Box’ -- Natural products drug discovery: on silica or in silico?- Quantitative NMR Methods in Metabolomics -- Advancements in pulsed stable isotope resolved metabolomics -- Metabolomics in Cell Biology -- NMR-based metabolomics to evaluate individual response to treatments -- Pharmacometabolomics of Asthma as a road map to Precision Medicine -- Prospective metabolomic studies in precision medicine -- Chemotherapy-induced Peripheral Neuropathy -- Metabolomics of Respiratory Diseases.
    Abstract: This volume of the Handbook of Experimental Pharmacology, which celebrated its 100th anniversary in 2019, addresses the rapidly growing and evolving field of metabolomics. It has been compiled and designed to broaden and enrich your understanding as well as simplify a complicated picture of the diverse field of metabolomics. This is accomplished by chapters from experts in the field on basic principles as well as reviews and updates of analytical techniques. The variety and different perspectives of the NMR approaches are described in the chapters By David Wishart, Daniel Raftery and Ryan McKay, while mass spectrometry advances are covered by Charles R. Evans and Stefan Kempa. This book also reflects the state of the art in the application of metabolomics to cell biology (Marta Cascante and Ulrich Guenther) and chapters that share insights into the application of metabolomics in various diseases (Paola Turano and Claudio Luchinat, Rachel S. Kelly and Jessica Lasky-Su, Paige Lacy, and Angela Rogers. Relationships of metabolomics with drugs are highlighted by Robert Verpoorte (natural products drug discovery), by Oscar Millet and by Turano and Luchinat (perspectives in precision medicine) and by Daniel L. Hertz (drug-induced peripheral neuropathy). From the above list of diverse topics, we believe this book has interdisciplinary appeal and scholars with an interest in the role of metabolomics in achieving precision medicine will find it of particular or special interest.
    Type of Medium: Online Resource
    Pages: VIII, 384 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031268595
    Series Statement: Handbook of Experimental Pharmacology, 277
    URL: https://doi.org/10.1007/978-3-031-26859-5
    DOI: 10.1007/978-3-031-26859-5
    DDC: 615
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    Structure and Health Effects of Natural Products on Diabetes Mellitus (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Botanical chemistry. ; Bioorganic chemistry. ; Pharmacology. ; Plant Biochemistry. ; Bioorganic Chemistry.
    Description / Table of Contents: Chapter 1. Introduction of diabetes melitus and future prospects of natural products on diabetes melitus -- Chapter 2. Anoverview of hypoglycemic modern drugs -- Chapter 3. An overview of hypoglycemic biological drugs -- Chapter 4. An overview of hypoglycemic traditionaldrugs -- Chapter 5. Glycosides from natural sources in the treatment of diabetes mellitus -- Chapter 6. Isolation and Structure Elucidation of Hypoglycemic Compounds -- Chapter 7. Structural Characterization and Health Effects of Polysaccharides from Momordica charantia on Diabetes Mellitus -- Chapter 8. Effects of polysaccharides on reducing blood glucose based on gut microbiota alteration -- Chapter 9. An Overview of Polysaccharides and the influencefactors of Hypoglycemic Activity -- Chapter 10. Plant Secondary Metabolites with α-Glucosidase Inhibitory Activity. - Chapter 11. Rhinacanthin-C and Its Potential to Control Diabetes Mellitus -- Chapter 12. Regeneration of beta cells by inhibition of pro-apoptotic proteins through phytocompound in STZ induced diabetic albino wistar rats-invivo and insilico approach. - Chapter 13. Nitrogenous Compounds from Plant Origin in Management of -- Chapter 14. Plant Alkaloids with Antidiabetic Potential -- Chapter 15. The role of Alkaloids in the Management of Diabetes Mellitus -- Chapter 16. Traditional Indian Herbs for the Management of Diabetes Mellitus and their Herb-Drug Interaction Potentials: An Evidence-Based Review -- Chapter 17. Role of Micronutrients and Trace elements in Diabetes mellitus: A Review.
    Abstract: The purpose of this book is to introduce the classified chemical components of hypoglycemic compounds in natural products, summarize the recent research progress of natural products with hypoglycemic activity in the past 20 years, and provide the original analysis and development opinions of relevant scholars. Hypoglycemic compounds are to target diabetes mellitus, an important public health problem, one of four priority noncommunicable diseases (NCDs) targeted for action by world leaders. Diabetes mellitus is a common endocrine and metabolic disease, which not only causes physiological damage to patients' kidneys, cardiovascular and cerebrovascular vessels, peripheral blood vessels, nerves and eyes, but also causes mental and psychological pressure to patients. Due to the evidence that traditional medicine and natural herbal formula have advantages in treating diabetes, natural products with hypoglycemic activity have been studied extensively in recent years and have been accepted by many scholars all over the world. This book focuses on the progress on the study of the structure, hypoglycemic activities, structure-activity relationships and mechanism of a wide range of polysaccharides, flavonoids, saponins, alkaloids, terpenoids, polyphenols and other constituents. It will help students and researchers to understand current approaches and progress in the treatment of diabetes with natural products, which may also be beneficial to develop new hypoglycemic drugs.
    Type of Medium: Online Resource
    Pages: VIII, 307 p. 85 illus., 16 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811587917
    URL: https://doi.org/10.1007/978-981-15-8791-7
    DOI: 10.1007/978-981-15-8791-7
    DDC: 615
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    Pharmacology of Immunosuppression (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Human physiology. ; Immunology. ; Surgery. ; Pharmacology. ; Human Physiology. ; Immunology. ; Surgery.
    Description / Table of Contents: Review of the Pathophysiology of the Alloimmune response -- A Comprehensive Review of Calcineurin Inhibitors Used for Immunosuppression in Cardiac Transplantation -- Anti-proliferative Agents -- Mechanistic Target of Rapamycin (mTOR) Inhibitors -- Corticosteroids -- Induction therapy and antibodies -- Immunosuppression and Heart Transplantation -- Immunosuppression and Lung Transplantation -- Immunosuppression and renal transplant recipients -- Immunosuppression in Rheumatologic and Auto-immune Disease -- Immunosuppression in Bone Marrow Transplantation -- Immunosuppression in Multiple Sclerosis and Other Neurologic Disorders -- Novel immunosuppressive agents for the treatment of organ transplants -- Adverse Effects of Immunosuppression: Infections -- Malignancy: An Adverse Effect of Immunosuppression -- Adverse Effects of Immunosuppression:Nephrotoxicity, Hypertension and Metabolic Disease.
    Abstract: The goal of this book is to provide a guide and detailed review of immunosuppression in terms of molecular mechanisms of action, side effects and clinical trials that validated their utility. This includes their use in solid organ transplantation, bone marrow transplantation and autoimmune diseases and inflammatory diseases. This book is a critical review of these topics and a vital resource.
    Type of Medium: Online Resource
    Pages: VIII, 348 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031051180
    Series Statement: Handbook of Experimental Pharmacology, 272
    URL: https://doi.org/10.1007/978-3-031-05118-0
    DOI: 10.1007/978-3-031-05118-0
    DDC: 615
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    Evidence Based Validation of Traditional Medicines : A comprehensive Approach (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Medical microbiology. ; Medicinal chemistry. ; Pharmacovigilance. ; Pharmacology. ; Medical Microbiology. ; Medicinal Chemistry. ; Drug Safety and Pharmacovigilance.
    Description / Table of Contents: Chapter 1. Global Approach for Drug Discovery and Development from Indian Traditional Medicine -- Chapter 2. Bioactive Natural Leads TargetingCancer Cell Metabolism -- Chapter 3. Omics Technologies and Development of Anti-diabetic Therapies from Prospective Natural Products -- Chapter 4. Amaryllidaceae Alkaloids as Anti-inflammatory Agents Targeting Cholinergic Anti-inflammatory Pathway: Mechanisms and Prospects -- Chapter 5. Neurodegenerative Diseases and Small Molecule Protein Chaperone Activator of Natural Origin -- Chapter 6. Role of Phytomolecules on the Basic Biology of Aging -- Chapter 7. Role of phytomedicine in alleviating oxidative stress mediated vascular complications in diabetes -- Chapter 8. Plant Based -Secretase (BACE-1) Inhibitors: A Mechanistic Approach to Encounter Alzheimer's Disorder -- Chapter 9. Bioactive Compounds of Mangroves as Potent Drug and in Nanoparticle Synthesis - Play a Pivotal Role in Combating Human Pathogens. Chapter 10. Medicinal Plants: A Rich Source of Bioactive Molecules Used in Drug Development -- Chapter 11. Cell-based Assays in Natural Product-based Drug Discovery -- Chapter 12. Allelochemicals: An Emerging Tool for Weed Management -- Chapter 13. Secondary Metabolites of Higher Plants as Green Preservatives of Herbal Raw Materials and Their Active Principles During Postharvest Processing -- Chapter 14. Importance of Chromatography Techniques in Phytomedicine Research -- Chapter 15. Reverse Pharmacology – A Tool for Drug Discovery From Traditional Medicine -- Chapter 16. Role of Modern Biological Techniques in Evidence-Based Validation of Ayurvedic Herbometallic Preparations -- Chapter 17. HPTLC Fingerprinting analysis of Phytoconstituents from Indigenous Medicinal Plants -- Chapter 18. Climate Change,Geographical Location and Other Allied Triggering Factors Modulate the Standardization and Characterization of Traditional Medicinal Plants: AChallenges and Prospect for Phyto-Drug Development -- Chapter 19. Molecular Docking Studies of Plant-Derived Bioactive Compounds: A Comprehensive in silico Standardization Approach -- Chapter 20. Standardization and Quality Evaluation of Botanicals with Special Reference to Marker Components -- Chapter 21. Analytical Standardization of Haridra Formulation by UV-VIS Spectrophotometry and RP-HPLC -- Chapter 22. Ethnobotanical survey: the foundation to evidence based validation of medicinal plants -- Chapter 23. Phytotherapeutics: The Rising Role of Drug Transporters in Herb-Drug Interactions with Botanical Supplements -- Chapter 24. An Insight into Herb Interactions: Clinical Evidence Based Overview -- Chapter 25. Pharmacovigilance of Herbal Medicines: An Overview -- Chapter 26. Herbal Drugs: Efficacy, Toxicity and Safety Issues -- Chapter 27. Herbal Drug Patenting -- Chapter 28. Safety and Regulatory Issues on Traditional Medicine Entrusted Drug Discovery -- Chapter 29. Pharmacovigilance of Herbal Medicine: An Evolving Discipline -- Chapter 30. Toxicity Studies Related to Medicinal Plants -- Chapter 31. Herb-Drug Interactions -- Chapter 32. Plant Based Traditional Herbal Contraceptive Use in India: Safety and Regulatory Issues -- Chapter 33. Traditional Medicine Stability and Pharmacokinetic Issue -- Chapter 34. Pharmacovigilance: Methods in developing the safety and acceptability of traditional medicines -- Chapter 35. Zoopharmacognosy (Plant-Animal Interaction) -- Chapter 36. Significance of Stability and Pharmacokinetic issues in Traditional Medicine -- Chapter 37. Pharmaceutical Formulations Development Based on the Polymers Obtained from Edible Plants: An Excellent Approach for the Betterment in Health Care Services -- Chapter 38. Evaluation of bioactivity of green nanoparticles synthesized from traditionally used medicinal plants: a review -- Chapter 39. Physicochemical, Micromeritics, Biomedical and Pharmaceutical Applications of Assam Bora Rice Starch -- Chapter 40. Natural Excipients in Pharmaceutical Formulations -- Chapter 41. A Wonder Plant Withania: Pharmacological and Chemical Perspectives -- Chapter 42. Immunomodulators and Phyto Drugs -- Chapter 43. Combined Effects of Plant Extracts on Ovarian Cell Functioning -- Chapter 44. Pterocarpussantalinus: A Wonder Gift of Nature -- Chapter 45. Phytochemicals And Investigations On Traditionally Used Medicinal Mushrooms -- Chapter 46. A Review On Investigational Studies Of Marine Macroalgae Spogomorpha Indica L -- Chapter 47. Validation of Traditional Claim of Oxalis debilis Kunth., An Ethnomedicinal Plant from North-eastern Region of India -- Chapter 48. Traditional Herbal Medicine Practiced in Plateau-Fringe and Rarh Districts of West Bengal, India -- Chapter 49. Pharmacology and Mechanisms of Natural Medicine in Treatment of Type 2 Diabetes Mellitus -- Chapter 50. Indian Traditional Herbs and Alzheimer’s Disease: Integrating Ethnobotany and Phytotherapy. .
    Abstract: The demand for traditional medicines, herbal health products, herbal pharmaceuticals, nutraceuticals, food supplements and herbal cosmetics etc. is increasing globally due to the growing recognition of these products as mainly non-toxic, having lesser side effects, better compatibility with physiological flora, and availability at affordable prices. In the last century, medical science has made incredible advances all over the globe. In spite of global reorganization and a very sound history of traditional uses, the promotion of traditional medicine faces a number of challenges around the globe, primarily in developed nations. Regulation and safety is the high concern for the promotion of traditional medicine. Quality issues and quality control, pharmacogivilane, scientific investigation and validation, intellectual property rights, and biopiracy are some key issues that restrain the advancement of traditional medicine around the globe. This book contains diverse and unique chapters, explaining in detail various subsections like phytomolecule, drug discovery and modern techniques, standardization and validation of traditional medicine, and medicinal plants, safety and regulatory issue of traditional medicine, pharmaceutical excipients from nature, plants for future. The contents of the book will be useful for the academicians, researchers and people working in the area of traditional medicine. .
    Type of Medium: Online Resource
    Pages: XII, 1151 p. 378 illus., 125 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811581274
    URL: https://doi.org/10.1007/978-981-15-8127-4
    DOI: 10.1007/978-981-15-8127-4
    DDC: 615
    Language: English
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    From Obesity to Diabetes (2022)
    Cham :Springer International Publishing :
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    Keywords: Pharmacology. ; Metabolism Disorders. ; Pharmacology. ; Metabolic Disease.
    Description / Table of Contents: Part I Obesity. Epidemiology of Obesity -- The Circadian Clock and Obesity -- Nutrition and Microbiome -- From Obesity to Diabetes: The Role of the Adipose Organ -- Targeting Epicardial Fat in Obesity and Diabetes Pharmacotherapy -- The Enteroendocrine System in Obesity -- Insights from Studies of White Adipose Tissue Using Single-Cell Approaches -- Obesity-Related Insulin Resistance: The Central Role of Adipose Tissue Dysfunction -- Obesity, Senescence, and Senolytics -- Obesity and Obstructive Sleep Apnea -- Part II Diabetes and Complications. Inter-Organ Crosstalk in the Development of Obesity-Associated Insulin Resistance -- Islet Inflammation and β Cell Dysfunction in Type 2 Diabetes -- NAFLD and NASH: The Metabolically Diseased Liver -- Diabetic Kidney Disease: From Pathogenesis to Novel Treatment Possibilities -- Diabetic Peripheral Neuropathy -- Part III Lifestyle Modifications and Future Treatments. Weight Loss Strategies -- Physical Activity, Obesity and Weight Loss Maintenance -- Bariatric/Metabolic Surgery -- Drugs for Treating Obesity -- Novel Drugs for Diabetes Therapy -- Novel Approaches to Restore Pancreatic Beta-Cell Mass and Function -- Precision Medicine and Obesity -- Targeting the Enteroendocrine System for Treatment of Obesity.
    Abstract: Obesity is a major risk factor for the development of type 2 diabetes and its associated complications, a major socio-economic burden for health care systems. The worldwide prevalence of obesity doubled since 1980 and as a consequence the number of patients with diabetes has been continuously rising with more than 450 Mio. people suffering from this disease at the present time. Substantial progress has been made in understanding the molecular pathways leading from excessive fat accumulation to metabolic perturbation and finally diabetes manifestation. This edition of the "Handbook of Experimental Pharmacology" aims to analyze new insight into the pathophysiology of obesity, to decipher the complex links to diabetes and its complications, and to collect most recent information on new strategies for prevention and treatment of obesity and diabetes.
    Type of Medium: Online Resource
    Pages: VIII, 513 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030999957
    Series Statement: Handbook of Experimental Pharmacology, 274
    URL: https://doi.org/10.1007/978-3-030-99995-7
    DOI: 10.1007/978-3-030-99995-7
    DDC: 615
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    Online Resource
    Immunity Boosting Medicinal Plants of the Western Himalayas (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Natural products. ; Botany. ; Ethnology. ; Pharmacology. ; Natural Products. ; Plant Science. ; Ethnography.
    Description / Table of Contents: 1. Introduction to Western Himalayas -- 2. Achillea millefolium L., Common Yarrow -- 3. Arisaema jacquemontii Blume, Jacquemont's Cobra Lily -- 4. Species of Arnebia genus found in the western Himalayas -- 5. Species of the Berberis genus found in the western Himalayas -- 6. Dactylorhiza hatagirea (D.Don) Soo – Himalayan Marsh Orchid -- 7. Fritillaria roylei Hook.f.: Himalayan Fritillary -- 8. Gentiana kurroo Royle: Himalayan Gentian -- 9. Habenaria intermedia D.Don and Habenaria edgeworthii Hook., f. ex Collett.: The Western Himalayan medicinal Plants -- 10. Humulus lupulus L.: Beer plant -- 11. Inula racemosa Hook. f. – Puskarmool: Its ethnobotanical uses, phytochemicals and pharmacological activities -- 12. Juniperus recurva Buch.-Ham. ex D.Don and Juniperus squamata D. Don: Himalayan Juniper -- 13. Lancea tibetica Hook.f. & Thomson: Ethnobotany, phytochemistry and pharmacology -- 14. Malaxis muscifera (Lindley) O. Kuntze. and Malaxis acuminata D. Don.: Jeevak -- 15. Picrorhiza kurroa Royle ex Benth.: Kutki -- 16. Species of the genus Polygonatum found in the Western Himalayas -- 17. Species of the genus Rhodiola found in the Western Himalayas -- 18. Saussurea lappa C.B. Clarke: Kushta/Kut -- 19. Saussurea lappa C.B. Clarke: Kushta/Kut -- 20. Species of the genus Selinum found in the western Himalayas -- 21. Swertia chirayita (Roxb. ex Flem.): Chirayata/Chiretta -- 22. Taxus wallichiana Zucc.: The Himalayan yew -- 23. Tribulus terrestris L.: Gokshur /Gokharu -- 24. Species the Genus Viola found in Western Himalayas.
    Abstract: This book presents a comprehensive guide to traditional immunity-boosting medicinal plants of the Himalayas, their traditional uses, phytochemistry, pharmacology, diversity, conversation, biotechnology, toxicology, as well as future prospective. All the chapters cover the latest advances in ethnobotany, phytochemistry, biochemistry, and biotechnology. The book offers a valuable asset for researchers and graduate students of chemistry, botany, biotechnology, microbiology, and the pharmaceutical sciences. The main purpose of the present book is to draw on the rich culture, folklore, and biodiversity of immunity-boosting medicinal plants of the Western Himalayas, with particular emphasis on the Indian Trans-Himalayan and Western Himalayan region. All the plants included in the present book are extensively used by the local tribes and people for their health-promoting properties from ancient times. This book will be a substantial contribution to the knowledge of the region and the country. Also, the book will be very useful to scientists, graduates, and undergraduates, along with researchers in the fields of natural products, herbal medicines, ethnobotany, pharmacology, chemistry, and biology. Further, it is an equally significant resource for a person working in different traditional medicinal systems; doctors (especially those engaged in Ayurveda, Chinese traditional medicinal system, Amchi, and allopathy); the pharmaceutical industry (for drug design and synthesis); biochemistry and biotechnology sciences; and the agricultural sciences. .
    Type of Medium: Online Resource
    Pages: XIX, 609 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811995019
    URL: https://doi.org/10.1007/978-981-19-9501-9
    DOI: 10.1007/978-981-19-9501-9
    DDC: 615
    Language: English
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    Nanoformulations in Human Health : Challenges and Approaches (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Therapeutics. ; Pharmacology. ; Therapeutics.
    Description / Table of Contents: Nano-technological Platforms and Manipulations for the Emerging Ocular Manifestations -- Phytonanomedicines as Topical Alternatives for the Treatment of Skin Cancer -- Nano-sized Labile and Particulate Ingredients in Topical Formulations: A Strategic Approach Against Photoageing and Photocarcinogenisis -- Application of Biocompatible Nanocarriers in Glaucoma: Challenges and Advances -- Nano-carriers for Natural Therapeutics in the Management of Neuropathic Pain -- Advances in the Delivery of Therapeutic Peptides -- Nanoformulations and Their Role in Colon Targeting -- Theranostic Nanoformulations: Merging Diagnostics and Therapeutics -- The Role of Nanoformulations in Nose-To-Brain Drug Delivery -- Cubic Lyotropic Liquid Crystalline Nanostructures: A Versatile Platform for Delivery -- Preformulation Challenges: The Concept Behind the Selection, Design, and Preparation of Nanoformulations -- Nanoethosomes for Topical Fungal Therapeutics -- Comparison of Therapeutic Efficiency of Nanoformulations of Curcumin vs. Tetrahydrocurcumin in Various Disorders -- Nanomedicinal Approaches of Phytotherapeutics to Treat Alzheimers Disease -- Nanoparticulate Approaches to Exploit the Pathophysiology of Rheumatoid and Osteoarthritis -- Emerging Nanotechnology in Chronic Respiratory Diseases -- Conventional and Non-conventional Approaches of Site-specific Targeting of Therapeutics in Some Infectious Diseases and Metabolic Disorders -- Nanoformulations in Human Health Conditions: The Paradigm Shift -- Magnetic Nanoparticles Nanoformulation for Alternative Therapy of Cancer by Super-paramagnetic Hyperthermia -- Nano-weapons Against Tuberculosis -- Drug-Excipient Interactions in Nanoformulations with Special Focus on Impurity Control per ICH guidelines.
    Abstract: This book is an amalgamation of knowledge, experience, and expertise in various aspects of nanotechnology, by experts who are proficient in designing novel nanoformulations that are used in the treatment of various challenging and prevalent diseases. It is an exhaustive compilation of the multi-faceted arena of nanoformulations and the healthcare system that caters to the needs of academicians, scholars, researchers, etc. The most important aspect of the book covers various types of nanoformulations and their applications in the treatment of communicable and non-communicable diseases. Each chapter focuses on a particular nanoformulation as well as a disease including the pathophysiology of the disease, the current treatment modalities of diseases, the role of nanoformulation in treatment and other future aspects and directions for further work. Coverage includes neuropathic pain, colon targeting, nose-to-brain drug delivery, cancer, arthritis and tuberculosis.
    Type of Medium: Online Resource
    Pages: XVIII, 548 p. 106 illus., 91 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030418588
    URL: https://doi.org/10.1007/978-3-030-41858-8
    DOI: 10.1007/978-3-030-41858-8
    DDC: 615
    Language: English
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  • 44
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    Emerging Technologies for Nanoparticle Manufacturing (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Nanotechnology. ; Nanochemistry. ; Pharmacology. ; Nanotechnology. ; Nanochemistry.
    Description / Table of Contents: Part 1 Introduction and Biomedical Applications of Nanoparticles -- 1. Introduction to Nanomaterials and Nanotechnology -- 2. Biomedical Applications of Nanoparticles -- Part II-Polymeric Nanoparticles -- 3. Nanocrystallization and Nanoprecipitation Technologies -- 4. Microfluidics Technology for Nanoparticles and Equipment-. 5. Production of Nanocomposites via Extrusion Techniques -- 6. The Use of Supercritical Fluids Technologies for Nanoparticle Production -- 7. Salting out and Ionic Gelation Manufacturing Techniques for Nanoparticles -- 8. Nanogel Synthesis by Irradiation of Aqueous Polymer Solutions -- 9. Cellulose acetate based nanofibers: Synthesis, Manufacturing and Applications -- 10. Production of nanofibers, environmental challenges and solutions -- Part III-Lipid Nanoparticles -- 11. High Pressure Homogenization Techniques for Nanoparticles -- 12. Solvent emulsification evaporation and solvent emulsification diffusion techniques for nanoparticles -- 13. Ultrasound Activated Nanoemulsions -- 14. Multiple Emulsions: Emphasizing on industrial applications -- 15. Membrane techniques for the preparation of nanomaterials -- 16. Self-assembling Lipid Nanoparticles/Nanosystems (SLNN) using Hydrophilic Solvents: Overview and Industrial Uses -- 17. Nanoemulsions – An emerging technology in drug delivery -- Part IV- Metallic Nanoparticles -- 18. Manufacturing techniques for carbon nanotubes, gold nanoparticles and silver nanoparticles -- 19. Radio frequency (RF) plasma-based Synthesis of metallic Nano particles for Biomedical Application -- 20. Techniques for accurate sizing of nanoparticles -- 21. Silver nanoparticles synthesis from cyanobacteria: Environmental and biomedical applications -- 22. Selenium Nanoparticles: Green Synthesis and Exploitation -- Part V- Quality control for nanoparticles -- 23. Practical guidelines for the characterization and quality control of nanoparticlesin the pharmaceutical industry -- Part VI-Challenges in scale-up production of nanoparticles -- 24. Nanomedicine Scale-Up Technologies: Feasibilities and Challenges -- 25. Patent survey on recent technology for nanoparticles -- Part VII-Injectable Nanosystems -- 26. Injectable Nanosystems and Inherent Nano-Serum Interactions -- Part VIII- Future directions and challenges -- 27. Current Challenges and Future Directions in Nanomedicine.
    Abstract: This book provides an overview of nanoparticle production methods, scale-up issues drawing attention to industrial applicability, and addresses their successful applications for commercial use. There is a need for a reference book which will address various aspects of recent progress in the methods of development of nanoparticles with a focus on polymeric and lipid nanoparticles, their scale-up techniques, and challenges in their commercialization. There is no consolidated reference book that discusses the emerging technologies for nanoparticle manufacturing. This book focuses on the following major aspects of emerging technologies for nano particle manufacturing. I. Introduction and Biomedical Applications of Nanoparticles II. Polymeric Nanoparticles III. Lipid Nanoparticles IV. Metallic Nanoparticles V. Quality Control for Nanoparticles VI. Challenges in Scale-Up Production of Nanoparticles VII. Injectable Nanosystems VIII. Future Directions and Challenges Leading scientists are selected as chapter authors who have contributed significantly in this field and they focus more on emerging technologies for nanoparticle manufacturing, future directions, and challenges. .
    Type of Medium: Online Resource
    Pages: XV, 611 p. 155 illus., 117 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030507039
    URL: https://doi.org/10.1007/978-3-030-50703-9
    DOI: 10.1007/978-3-030-50703-9
    DDC: 615
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  • 45
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    Online Resource
    Antiviral Drug Discovery and Development (2021)
    Singapore :Springer Nature Singapore :
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    Keywords: Pharmacology. ; Pharmacy. ; Biotechnology. ; Pharmacology. ; Pharmacy. ; Biotechnology.
    Description / Table of Contents: 1 Antiviral Drugs Against Herpesviruses -- 2 An Update on Antiretroviral Therapy -- 3 Structural Insights to Human Immunodeficiency Virus (HIV-1) Targets and their Inhibition -- 4 LEDGINs, Inhibitors of the Interaction between HIV-1 Integrase and LEDGF/p75, are Potent Antivirals with a Potential to Cure HIV Infection -- 5 Moving Fast Towards Hepatitis B Virus Elimination -- 6 Discovery and Development of Antiviral Therapies for Chronic Hepatitis C Virus Infection -- 7 Phytoconstituents as Lead Compounds for Anti-dengue Drug Discovery -- 8 Anti-influenza Drug Discovery and Development: Targeting the Virus and its Host by all -- 9 Search, Identification and Design of Effective Antiviral Drugs against Pandemic Human Coronaviruses -- 10 Peptide Based Antiviral Drugs -- 11 Covalent Antiviral Agents -- 12 Safe-in-Man Broad Spectrum Antiviral Agents -- 13 Exploiting Ubiquitin ligases for Induced Target Degradation as an Antiviral Strategy. .
    Abstract: This book summarizes state-of-the-art antiviral drug design and discovery approaches starting from natural products to de novo design, and provides a timely update on recently approved antiviral drugs and compounds in advanced clinical development. Special attention is paid to viral infections with a high impact on the world population or highly relevant from the public health perspective (HIV, hepatitis C, influenza virus, etc.). In these chapters, limitations associated with adverse effects and emergence of drug resistance are discussed in detail. In addition to classical antiviral strategies, chapters will be dedicated to discuss the non-classical drug development strategies to block viral infection, for instance, allosteric inhibitors, covalent antiviral agents, or antiviral compounds targeting protein–protein interactions. Finally, current prospects for producing broad-spectrum antiviral inhibitors will be also addressed. The book is distinctive in providing the most recent update in the rapidly evolving field of antiviral therapeutics. Authoritative reviews are written by international scientists well known for their contributions in their topics of research, which makes this book suitable for researchers not only within the antiviral research community but also attractive to a broad audience in the drug discovery field. This book covers molecular structures and biochemical mechanisms mediating the antiviral effects, while discussing various ligand design strategies, which include traditional medicinal chemistry, computational chemistry, and chemical biology approaches. The book provides a comprehensive review of antiviral drug discovery and development approaches, particularly focusing on current innovations and future trends.
    Type of Medium: Online Resource
    Pages: XI, 357 p. 142 illus., 64 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811602672
    Series Statement: Advances in Experimental Medicine and Biology, 1322
    URL: https://doi.org/10.1007/978-981-16-0267-2
    DOI: 10.1007/978-981-16-0267-2
    DDC: 615
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  • 46
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    Voltage-gated Ca2+ Channels: Pharmacology, Modulation and their Role in Human Disease (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Medical genetics. ; Human physiology. ; Pharmacology. ; Medical Genetics. ; Human Physiology.
    Description / Table of Contents: Preface -- Part 1 Modulation -- Cav1.1Calcium Channel Signaling Complexes in Excitation–Contraction Coupling: Insights from Channelopathies -- Mechanisms of Vascular CaV1.2 Channel Regulation During Diabetic Hyperglycemia -- Sympathetic Nervous System Regulation of Cardiac Calcium Channels -- Modulation of CaV1.2 Channel Function by Interacting Proteins and Post-Translational Modifications: Implications in Cardiovascular Diseases and COVID-19 -- Part 2 Pharmacological Approaches -- Pathophysiological Roles of Auxiliary Calcium Channel α2δ Subunits -- Design and Applications of Genetically-Encoded Voltage-Dependent Calcium Channel Inhibitors -- Part 3 Disease insight from channelopathies: consequences for pharmacology and therapeutic strategies -- CACNA1C-Related Channelopathies -- CACNA1D-Related Channelopathies: From Hypertension to Autism -- CACNA1A-Related Channelopathies: Clinical Manifestations and Treatment Options -- CaV3.2 (CACNA1H) in Primary Aldosteronism,- CaV3.3 Channelopathies -- Pathophysiological Roles of Auxiliary Calcium Channel α2δ Subunits.
    Abstract: The aim of this volume is to summarize novel findings on the function, pathophysiology, and regulation of voltage-gated Ca2+ channels and on novel concepts of their pharmacological modulation. Impressive insights into the role of channel function and regulation have come from Ca2+ channelopathies affecting the pore-forming as well as accessory subunits and channel-interacting proteins. Moreover, the long-sought molecular basis for key regulatory pathways have been discovered as well as exciting concepts of their subtype-selective pharmacological modulation.
    Type of Medium: Online Resource
    Pages: XII, 316 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031384370
    Series Statement: Handbook of Experimental Pharmacology, 279
    URL: https://doi.org/10.1007/978-3-031-38437-0
    DOI: 10.1007/978-3-031-38437-0
    DDC: 615
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  • 47
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    Edible Plants in Health and Diseases : Volume II : Phytochemical and Pharmacological Properties (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Food science. ; Medicinal chemistry. ; Pharmacology. ; Food Science. ; Medicinal Chemistry.
    Description / Table of Contents: 1 Zingiber officinale - Its Ethanobotanical Uses, Phytochemistry and Pharmacology -- 2 An Insight in to the Phytochemistry, Traditional uses and Pharmacology of Ziziphus spina-christi (L) Willd. (Sidr): An Edible wild plant of Arabian Peninsula -- 3 Traditional Uses, Phytochemistry and Pharmacological Profile of Salvadora persica Linn -- 4 Phytochemistry, Pharmacology and Applications of Ocimum sanctum (Tulsi) -- 5 Nigella sativa: Its Ethnobotany, Phytochemistry and Pharmacology -- 6 A Review on Ethnomedicinal, Phytochemistry and Pharmacological Activities of Rumex hastatus D. Don -- 7 Chemical Composition and Biological Uses of Crocus sativus L.(Saffron) -- 8 Positive Health Benefits of Saponins from Edible Legumes: Phytochemistry and Pharmacology -- 9 Taraxcum officinale: The Esculent Dandelion as Herbal Medicine -- 10 Arctium lappa: A Review on its Phytochemistry and Pharmacology -- 12 Cichorium intybus: A Comprehensive Review on its Pharmacological Activity and Phytochemistry -- 13 Phytochemical and Pharmacological Properties of Picrorhiza kurroa -- 14 Lady's Purse (Capsella bursa-pastoris L.)-Current perspective on its ethanopharmacological, therapeutic potential and phytochemistry -- 15 Ethnopharmaology, Phytochemistry and Biological Activities of Achillea millefolium: A Comprehensive Review -- 16 A Review on Traditional Uses, Phytochemistry and Pharmacological Activities of Verbascum thapsus -- 17 Acorus calamus - A Review on Its Phytochemical and Pharmacological Profile.
    Abstract: The book provides essential information on some of the promising edible medicinal plants and how these possess both nutritional as well as therapeutic value. The significance of the edible plants in traditional medicine and the importance of the distribution of their chemical constituents are discussed systematically concerning the role of these plants in ethnomedicine in different regions of the world. The current volume deals with the individual plants' phytochemical and pharmacological properties, emphasizing human health. The title would demonstrate the value of natural edible plants and introduce readers to state-of-the-art developments and trends in omics-driven research. This book is a single-source scientific reference to explore the specific factors that contribute to these potential health benefits and discuss how to maximize those potential benefits. Chemists, food technologists, pharmacologists, phytochemists, and all professionals involved with quality control and standardization will find in this book a valuable and updated basis for their work.
    Type of Medium: Online Resource
    Pages: IX, 522 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811649592
    URL: https://doi.org/10.1007/978-981-16-4959-2
    DOI: 10.1007/978-981-16-4959-2
    DDC: 615
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  • 48
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    The Kappa Opioid Receptor (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Pharmacology.
    Description / Table of Contents: From the contents. Preface.-Part I: Molecular aspects of KOR -- Part II: Preclinical research on pharmacology of KOR agonists and antagonists in animals -- Part III: KOR agonists and antagonists in clinical use and in past and present clinical trials.
    Abstract: This book covers the latest knowledge in structure, signaling, and biochemical pharmacology of KOR as well as preclinical research and clinical applications (including clinical phase studies and approved for human use) of KOR compounds. It is divided up into the three parts: Molecular aspects of KOR, Preclinical research on pharmacology of KOR agonists and antagonists in animals and KOR agonists and antagonists in clinical use and in past and present clinical trials. The chapters "Biosensors monitor ligand-selective effects at kappa opioid receptors" and "The role of dynorphin and the kappa opioid receptor in schizophrenia and major depressive disorder: a translational approach" of this book are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Type of Medium: Online Resource
    Pages: XI, 577 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030890742
    Series Statement: Handbook of Experimental Pharmacology, 271
    URL: https://doi.org/10.1007/978-3-030-89074-2
    DOI: 10.1007/978-3-030-89074-2
    DDC: 615
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  • 49
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    Behavioral Neurobiology of GABAB Receptor Function (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Neurosciences. ; Psychiatry. ; Pharmacology. ; Neuroscience. ; Psychiatry.
    Abstract: It has been almost forty years since Norman G. Bowery discovered and named this “non-GABAA” receptor the GABAB receptor. It has been almost ten years since the last comprehensive book presentation focused on GABAB receptors. The main goal of this book is to provide the field with a contemporary and comprehensive perspective on the GABAB receptor, its physiological relevance, and its therapeutic potential. The volume is organized into introductory and special interest sections presented by experts who study the GABAB receptor from structural, signaling, pharmacologic, physiological, pathophysiological, and therapeutic perspectives. The book aims to appeal to a broad spectrum of biomedical and clinical scientists - any scholars with an interest in GABAB receptor. The editors hope readers find this work to be thought-provoking, instructive, and informative.
    Type of Medium: Online Resource
    Pages: VII, 329 p. 70 illus., 15 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030913359
    Series Statement: Current Topics in Behavioral Neurosciences, 52
    URL: https://doi.org/10.1007/978-3-030-91335-9
    DOI: 10.1007/978-3-030-91335-9
    DDC: 615
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  • 50
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    Marine Biomaterials : Drug Delivery and Therapeutic Applications (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Medicine Research. ; Biology Research. ; Biomaterials. ; Pharmacy. ; Biomedical engineering. ; Pharmacology. ; Biomedical Research. ; Biomaterials. ; Pharmacy. ; Translational Research. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: Chapter 1. Marine biopolymers for oral delivery of drug -- Chapter 2. Marine polymer based nanocarriers for drug delivery application -- Chapter 3. Alginate: A promising biopolymer in drug delivery system -- Chapter 4. Chitosan Based Nanocomposite as Targeted drug delivery Carrier -- Chapter 5. Marine Biopolymer Based Oral In situ Gel: Drug Delivery Applications -- Chapter 6. Marine biopolymers for transdermal drug delivery -- Chapter 7. Marine polysaccharides for skin drug delivery: hydrogels and microneedles solutions -- Chapter 8. Marine collagen: promising biomaterial in delivery of therapeutics for cancer therapy -- Chapter 9. Chitosan based gel for ocular drug delivery. Chapter 10. Marine based biopolymers for central nervous system drug delivery -- Chapter 11. Marine Biopolymers Based Anticancer Drug Delivery Systems -- Chapter 12. Marine-Derived polysaccharides: prospects for future pharmaceuticals and drug delivery systems.
    Abstract: This book is focused on marine based biomedical carriers for delivery of therapeutics. Marine biomaterials and bio-based carriers show wide applications in pharmaceutical as well as biomedical fields for delivery of small and large molecules. Biomaterial-based composites, scaffolds or matrix systems are promising systems for controlled and prolonged release of drug in target site and control the premature release of drugs or bioactive compounds. This book discusses the targeted delivery of drugs and therapeutic applications. It also describes the use of marine biopolymers in cancer therapy. Different chapters describe the tissue engineering techniques to develop these carriers. The marine biomaterial-based systems are widely used for tissue engineering, and biomedical imaging. This book is meant for industry experts, students and researchers in the area of pharmaceutical sciences, biomedical engineering and material science and pharmacology.
    Type of Medium: Online Resource
    Pages: X, 453 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811647871
    URL: https://doi.org/10.1007/978-981-16-4787-1
    DOI: 10.1007/978-981-16-4787-1
    DDC: 615
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  • 51
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    Parkinsonism and the Environment (2022)
    Cham :Springer International Publishing :
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    Keywords: Pharmacology. ; Neurosciences. ; Pharmacology. ; Neuroscience.
    Description / Table of Contents: Experimental evidence for pesticide contribution in the pathogenesis of Parkinsonism: an update -- Epidemiological evidence for pesticide involvement in the etiology of Parkinson’s Disease: current state of affairs?” -- Manganese induced Parkinsonism: cellular and molecular mechanisms -- Manganese overexposures in occupational and environmental settings and Parkinsonism: where do we stand -- Aberrant dopamine metabolism as a focal point in the mechanism of environmental contaminant-induced dopaminergic dysfunction -- Emerging contaminants as contributors to Parkinsonism: focus on PhiPs -- Emerging contaminants as contributors to Parkinsonism: focus on PhiPs -- Protein kinase C-delta (PKC-delta): a major molecular target for disparate dopaminergic toxicants -- Environmental contribution to redox dyshomeostasis in Parkinsonism.
    Abstract: “The book is comprised of individual reviews with the common goal of providing up-to-date state of the knowledge information on the role the environment plays in the pathogenesis of parkinsonism. The reviews focus on recent advances in the quest of deciphering the molecular and cellular mechanisms of parkinsonian dysfunction, highlight specific emerging dopaminergic toxicants and an alternative experimental model to study the link between environmental exposures and parkinsonism, and provide an update from epidemiological and experimental points of view related to the pesticide exposures and parkinsonism/Parkinson’s Disease association. Foremost experts in their respective fields are the senior authors on each chapter and the book fills a critical void that now exists as a book of similar nature has not been published in the last 15 years. Researchers and clinicians with an interest in Parkinson's Disease and related disorders, as well as toxicologists, graduate students, and the general public who are interested in the contribution of environmental factors to neurological dysfunction are among the readership for this book.”.
    Type of Medium: Online Resource
    Pages: V, 158 p. 14 illus., 8 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030874513
    Series Statement: Molecular and Integrative Toxicology,
    URL: https://doi.org/10.1007/978-3-030-87451-3
    DOI: 10.1007/978-3-030-87451-3
    DDC: 615
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    Ethnopharmacology and Drug Discovery for COVID-19: Anti-SARS-CoV-2 Agents from Herbal Medicines and Natural Products (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Natural products. ; Nanobiotechnology. ; Bioinformatics. ; Diseases Causes and theories of causation. ; Molecular biology. ; Pharmacology. ; Natural Products. ; Nanobiotechnology. ; Bioinformatics. ; Pathogenesis. ; Molecular Biology.
    Description / Table of Contents: 1. COVID-19: An overview of virology, mutations, pathology, epidemiology, diagnosis, preventions and treatments -- 2. The recent development of therapeutic strategies against COVID-19 -- 3. Plant immunoenhancers: Promising ethnopharmacological candidates for anti-SARS-CoV-2 activity -- 4. Herbal formulations in fighting against the SARS-CoV-2 infection -- 5. Rejuvenation of traditional medicine in the 21st century against SARS-CoV-2 -- 6. Traditional herbal medicines and their active constituents in combating SARS-CoV-2 infection -- 7. Antiviral phytocompounds against animal-to-human transmittable SARS-CoV-2 -- 8. Plants-derived bioactive compounds as potential ACE-2 inhibitors against SARS-CoV-2 infection -- 9. Insights into in silico methods to explore plant bioactive substances in combating SARS-CoV-2 -- 10. Dietary plants, spices and fruits in curbing SARS-CoV-2 virulence -- 11. Therapeutic potential of selected medicinal plants for neurological disorders after the infection of COVID-19 -- 12. Glycyrrhizae Radix et Rhizoma (Gan Cao) for the management of COVID-19 -- 13. COVID-19-induced kidney disease: Ethnopharmacological intervention to ameliorate kidney damage and improve kidney function -- 14. Phytochemicals and nutraceuticals targeting SARS-CoV-2: An in silico analysis -- 15. Therapeutic and prophylactic effects of plant derivatives against SARS-CoV-2 -- 16. Therapeutic potential of essential oils against SARS-CoV-2 infection -- 17. Antiviral properties of South Indian plants against SARS-CoV-2 -- 18. Immune-boosting plants used in Turkish folk medicine and their potential against COVID-19 -- 19. A comparison study of medicinal plants used against SARS-CoV-2 and those recommended against malaria in Africa -- 20. Exploring the potential antiviral properties of Nigella sativa L. against SARS-CoV-2: Mechanisms and prospects -- .
    Abstract: This book presents a complete overview of COVID-19 and provides a series of in-depth analyses of the literature and a comprehensive discussion and perspectives on promising anti-SARS-CoV-2 agents based on the system of ethnopharmacology, which covers Chinese medicine, traditional medicines of India and Africa, Turkish folk medicine, essential oils, and some well-known medicinal plants. In this book, the current status of therapeutic strategies against COVID-19 was summarized and a perspective of potential options for the future was proposed. Based on ethnopharmacology, some well-established traditional herbal formulations and bioactive compounds with anti-virus activity were repurposed for managing COVID-19 and post-illness, including neurological disorders and kidney illness. Using drug discovery tools, promising immune enhancers were explored from phytochemicals against SARS-CoV-2. Nutraceuticals from dietary plants, spices, and fruits with anti-virus and antioxidant activities were recommended to prevent infection or severe illness caused by emerging variants. With the aid of systems pharmacology, researchers have gained insights into possible molecular mechanisms of anti-SARS-CoV-2 activity and have predicted a range of candidate compounds from medicinal plants to combat COVID-19. This book explores the current knowledge of drug discovery and ethnopharmacology for managing coronavirus diseases. The content proved the anti-SARS-CoV-2 activity from natural products and traditional herbal medicines. It contributes to the management of global public health and fits the goal of establishing “Good Health and Well-Being,” which is one of “The Sustainable Development Goals (SDGs) 2030".
    Type of Medium: Online Resource
    Pages: IX, 590 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819936649
    URL: https://doi.org/10.1007/978-981-99-3664-9
    DOI: 10.1007/978-981-99-3664-9
    DDC: 615
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    Novel Drug Targets With Traditional Herbal Medicines : Scientific and Clinical Evidence (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Toxicology. ; Pharmaceutical chemistry. ; Medicinal chemistry. ; Natural products. ; Pharmacology. ; Toxicology. ; Pharmaceutics. ; Medicinal Chemistry. ; Natural Products.
    Description / Table of Contents: Chapter 1: Achillea biebersteinii Afan -- Chapter 2: Aesculus hippocastanum L. -- Chapter 3: Berberis crataegina DC. -- Chapter 4: Calendula officinalis L. -- Chapter 5: Camellia sinensis (L.) Kuntze -- Chapter 6: Capsella bursa-pastoris (L.) Medik. -- Chapter 7: Capsicum annuum L. -- Chapter 8: Cedrus libani A.Rich. -- Chapter 9: Chelidonium majus L. -- Chapter 10: Cichorium intybus L. -- Chapter 11: Cistus laurifolius L. -- Chapter 12: Coriandrum sativum L. -- Chapter 13: Cornus mas L. -- Chapter 14: Curcuma longa L..-Chapter 15: Cydonia oblonga Mill. -- Chapter 16: Cynara scolymus L. -- Chapter 17: Equisetum arvense L. -- Chapter 18: Foeniculum vulgare Mill. -- Chapter 19: Fraxiınus ornus L. -- Chapter 20: Fumaria officinalis L. -- Chapter 21: Helichrysum plicatum DC. -- Chapter 22: Hyoscyamus niger L. -- Chapter 23: Juglans regia L. -- Chapter 24: Laurus nobilis L. -- Chapter 25: Liquidambar orientalis Miller -- Chapter 26: Matricaria chamomilla L. -- Chapter 27: Melissa officinalis L. -- Chapter 28: Momordica charantia L. -- Chapter 29: Nigella sativa L. -- Chapter 30: Olea europaea L. -- Chapter 31: Papaver somniferum L. -- Chapter 32: Rheum ribes L. -- Chapter 33: Rosa canina L. -- Chapter 34: Rosmarinus officinalis L. -- Chapter 35: Silybum marianum L. Gaertn. -- Chapter 36: Urtica dioica L -- Chapter 37: Valeriana officinalis L. -- Chapter 38: Viburnum opulus L.
    Abstract: This book collects information about the most popular ethnomedicinal plants, which are common in Turkey and around the world. It presents the ethnopharmacological records, in vivo and in vitro studies, side effects, chemical compositions and clinical studies of these medicinal plants. Its special focus is on the novel drug targets for disease and their possible mechanisms of action. It covers botanical descriptions the status of the plants, and food or drug interactions including precautions and warnings about the plants and the available market products. It provides an explanation of recorded and known plant administration dosages. Also, the gap between the traditional practice and scientific/clinical evidences in the use of ethnomedicinal plant is acknowledged. It is well known that traditional knowledge of the use of the medicinal plants in therapy is an important resource for the discovery of novel treatment options and drug targets. The main purpose of this book is to draw attention to ethnomedicinal plant species. Data on the therapeutic potentials of these medicinal plants can now be accessed from a single source. It provides an important resource for future research opportunities for harnessing the full potential of these plants.
    Type of Medium: Online Resource
    Pages: XII, 588 p. 119 illus., 43 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031077531
    URL: https://doi.org/10.1007/978-3-031-07753-1
    DOI: 10.1007/978-3-031-07753-1
    DDC: 615
    Language: English
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    Herb-Drug Combinations : A New Complementary Therapeutic Strategy (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Pharmacy. ; Alternative medicine. ; Pharmacovigilance. ; Medicinal chemistry. ; Pharmacology. ; Pharmacy. ; Complementary and Alternative Medicine. ; Drug Safety and Pharmacovigilance. ; Medicinal Chemistry.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. Measuring Herb-drug interaction and Synergy -- Chapter 3. Herb-Herb and Food-drug interactions -- Chapter 4. Pharmacokinetic interactions in synergistic herb-drug combinations -- Chapter 5. Antagonistic Herb-drug interactions -- Chapter 6. Synergistic Herb-drug interactions against bacteria -- Chapter 7. Synergistic herb-drug interactions against tuberculosis -- Chapter 8. Synergistic herb-drug interactions against viral diseases -- Chapter 9. Synergistic herb interactions with cardiovascular drugs -- Chapter 10. Synergistic herb interactions with anticancer drugs -- Chapter 11. Synergistic herb interactions with antidiabetic drugs -- Chapter 12. Synergistic herb-drug interactions against obesity -- Chapter 13. Synergistic Herb-Drug Interactions in Neurological Disorders -- Chapter 14. Synergistic Herb-drug interactions with antifungal and antiparasitic agents -- Chapter 15. Computational methods to study herb-drug interactions -- Chapter 16. Regulations and guidelines involving synergistic plant-drug interactions -- Chapter 17. Clinical trials on synergistic herb-drug interactions -- Chapter 18. QFuture prospects on synergistic herb-drug interactions -- Chapter 19. Conclusion.
    Abstract: Plant extracts or their pure natural constituents have been used traditionally for thousands of years for treating diseases with considerable success in India and other Asian countries. In addition, they have also been used as complements or supplements with conventional medicine. This book discusses the latest research in the application of combination therapy, namely herbs and drugs, in the treatment of a range of communicable and non-communicable diseases to achieve a synergistic effect. This synergy may help in reducing the amount of drug, its toxicity, side effects, and development of resistance as well as improve its efficacy. The book also discusses the pharmacodynamic and pharmacokinetic parameters, experimental tools to determine the impact of combination, computational approaches to identify synergy, statistical analysis of data, and clinical and regulatory issues. The book is useful for researchers in the fields of pharmacology, pharmacy and medicinal chemistry and those working in pharmaceutical and nutraceutical industries. This book could open up new strategies to focus on multiple targets to combat complex diseases unlike the single targeted drugs that are being currently marketed by the pharmaceuticals industries.
    Type of Medium: Online Resource
    Pages: XV, 276 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811951251
    URL: https://doi.org/10.1007/978-981-19-5125-1
    DOI: 10.1007/978-981-19-5125-1
    DDC: 615
    Language: English
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    Sex and Gender Effects in Pharmacology (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Immunology. ; Neurology . ; Endocrinology. ; Cardiology. ; Pharmacology. ; Immunology. ; Neurology. ; Endocrinology. ; Cardiology.
    Description / Table of Contents: Part 1 Pharmacological Basic Principles -- The impact of sex and gender in medicine and pharmacology -- Sex differences in pharmacokinetics -- Clinical pharmacological considerations in transgender medicine -- Sex and gender differences in the pharmacology of the overactive urinary bladder -- Part 2 Pathologies of the Brain -- Sex differences in the evaluation and treatment of stroke -- Sex differences in pain and its treatment -- Therapeutics For Substance-Using Women: The Need To Elucidate Sex-Specific Targets For Better-Tailored Treatments -- Intersection of sex and depression: pathogenesis, presentation and treatments -- Biological and clinical implications of sex-specific differences in Alzheimer’s disease -- Part 3 Diabetes, metabolic diseases & cardiovascular risk -- Gender Differences In Cardiovascular Health: Hormonal Effects on Cardiovscular Risk And Management. - Sex Differences in Glucose Homeostasis -- Sex-gender-based differences in metabolic diseases -- Hypothalamic pituitary gonadal axis disorders impacting fertility in both sexes and the potential of kisspeptin-based therapies to treat them.
    Abstract: Biological sex and gender have a tremendous impact on the efficacy and safety of pharmacological interventions in virtually every disease state. This book presents a comprehensive and up-to-date overview on how sex-specific information is guiding the diagnosis and treatment of diseases affecting men and women, as well as of disease states that disproportionally affects women. Experts in various fields discuss both preclinical and clinical research that is contributing to a better understanding of the impact of sex in the presentation, etiology, treatment, and disease outcomes. Also discussed are the challenges encountered in implementing this growing body of knowledge into practice, as well as possible avenues to recognize and reduce health disparities between men and women so that therapeutic interventions are tailored and improved.
    Type of Medium: Online Resource
    Pages: VIII, 288 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031426483
    Series Statement: Handbook of Experimental Pharmacology, 282
    URL: https://doi.org/10.1007/978-3-031-42648-3
    DOI: 10.1007/978-3-031-42648-3
    DDC: 615
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    Before the Collapse : A Guide to the Other Side of Growth (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Environment. ; Economic sociology. ; Nonlinear Optics. ; Dynamics. ; Nonlinear theories. ; Economics. ; Condensed matter. ; Environmental Sciences. ; Economic Sociology. ; Nonlinear Optics. ; Applied Dynamical Systems. ; Political Economy and Economic Systems. ; Phase Transitions and Multiphase Systems.
    Description / Table of Contents: Forword by Susan Kucera -- The Science of Doom: Modeling the Future -- Complex Systems and the Science of Collapse -- The Practice of Collapse -- Strategies for Managing Collapse -- What can we Learn from Seneca? -- Six things you should know before collapse.
    Abstract: Nobody has to tell you that when things go bad, they go bad quickly and seemingly in bunches. Complicated structures like buildings or bridges are slow and laborious to build but, with a design flaw or enough explosive energy, take only seconds to collapse. This fate can befall a company, the stock market, or your house or town after a natural disaster, and the metaphor extends to economies, governments, and even whole societies. As we proceed blindly and incrementally in one direction or another, collapse often takes us by surprise. We step over what you will come to know as a “Seneca cliff”, which is named after the ancient Roman philosopher, Lucius Annaeus Seneca, who was the first to observe the ubiquitous truth that growth is slow but ruin is rapid. Modern science, like ancient philosophy, tell us that collapse is not a bug; it is a feature of the universe. Understanding this reality will help you to see and navigate the Seneca cliffs of life, or what Malcolm Gladwell called “tipping points.” Efforts to stave off collapse often mean that the cliff will be even steeper when you step over it. But the good news is that what looks to you like a collapse may be nothing more than the passage to a new condition that is better than the old. This book gives deeper meaning to familiar adages such as “it’s a house of cards”, “let nature take its course”, “reach a tipping point”, or the popular Silicon Valley expression, “fail fast, fail often.” As the old Roman philosopher noted, “nothing that exists today is not the result of a past collapse”, and this is the basis of what we call “The Seneca Strategy.” This engaging and insightful book will help you to use the Seneca Strategy to face failure and collapse at all scales, to understand why change may be inevitable, and to navigate the swirl of events that frequently threaten your balance and happiness. You will learn: How ancient philosophy and modern science agree that failure and collapse are normal features of the universe Principles that help us manage, rather than be managed by, the biggest challenges of our lives and times Why technological progress may not prevent economic or societal collapse Why the best strategy to oppose failure is not to resist at all costs How you can “rebound” after collapse, to do better than before, and to avoid the same mistakes.
    Type of Medium: Online Resource
    Pages: XVIII, 242 p. 55 illus., 22 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030290382
    URL: https://doi.org/10.1007/978-3-030-29038-2
    DOI: 10.1007/978-3-030-29038-2
    DDC: 333.7
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    Study of Ecological Engineering of Human Settlements (2020)
    Singapore :Springer Nature Singapore :
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    Keywords: Environment. ; Applied ecology. ; Pollution. ; Environmental Sciences. ; Applied Ecology. ; Pollution.
    Description / Table of Contents: Environmental problems of human settlements and countermeasures based on ecological engineering -- Soil environmental deterioration and ecological rehabilitation -- Amelioration and utilization of saline-alkali land -- Forestry ecological engineering in coastal saline-alkali soils -- Mined lands reclamation by vegetation restoration -- Soil Improvement and Vegetation Construction Technology in Abandoned land of Copper Mining Area -- Discussion on non-point source pollution and control in water source areas -- Impact of landscape pattern changes on water quality -- Eco-village construction and pollution control effect analysis -- Discussion on the overall planning of forest town construction in Simen Town, Yuyao City -- Study on the construction mode of rural human settlement forest in the eastern Zhejiang plain -- Evaluation of air negative ion effect in rural human settlement forests -- Determination of air anion level in Shanghai coastal shelter forests -- Effects of different greening modes of expressways on air environment -- Research on noise reduction effect of green belts on expressway -- Biodiversity protection technology in the construction of rural landscape -- Impacts of rural Fengshui forest construction on biodiversity -- Distribution characteristics of plant diversity in rural habitats-case study in Xiaoluxia village Index.
    Abstract: This book analyzes the theory of ecological engineering of human settlements and provides case studies on the improvement of degraded lands and vegetation restoration, especially focusing on saline-alkali land, abandoned land, water source areas, and the impact of green belts on noise and air quality on the highways. In addition, it discusses the issue of biodiversity conservation strategies in rural landscape construction and demonstrates experiment measurement and field survey methods. The results obtained are supplemented by numerical calculations, presented in the form of tables and figures. As the first monograph on this subject, the book provides a wealth of ideas and resources for researchers, professionals and practitioners in the field of human settlements.
    Type of Medium: Online Resource
    Pages: XXI, 415 p. 267 illus., 200 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811513732
    URL: https://doi.org/10.1007/978-981-15-1373-2
    DOI: 10.1007/978-981-15-1373-2
    DDC: 333.7
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    Contemporary Environmental Issues and Challenges in Era of Climate Change (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Environment. ; Environmental health. ; Conservation biology. ; Ecology . ; Environmental monitoring. ; Energy policy. ; Energy and state. ; Environmental Sciences. ; Environmental Health. ; Conservation Biology. ; Environmental Monitoring. ; Energy Policy, Economics and Management.
    Description / Table of Contents: Chapter 1. Ecosystem health and dynamics: An indicator of Global Climate Change -- Chapter 2. A comprehensive evaluation of heavy metals contamination in foodstuff and associated human health risk: a global perspective -- Chapter 3. Climate change impact on forest and agro-biodiversity: A special reference to Amarkantak Area, Madhya Pradesh -- Chapter 4. Agriculture sustainability and climate change nexus -- Chapter 5. Heat Stress in crops: Driver of climate change impacting global food supply -- Chapter 6. India’s major subsurface pollutants under future climatic scenarios: Challenges and remedial solutions -- Chapter 7. Phosphorus sorption characteristics of the surface sediments from industrially polluted GBPS reservoir, India -- Chapter 8. Spatio-temporal variations of precipitation and temperatures under CORDEX Climate Change Projections: A Case study of Krishna River Basin, India -- Chapter 9. Microorganisms in maintaining food and energy security in a world of shifting climatic conditions -- Chapter 10. Engineering Photosynthetic Microbes for Sustainable Bioenergy Production -- Chapter 11. Ensuring energy and food security through solar energy utilization -- Chapter 12. A Conceptual Framework to Social Life Cycle Assessment of e-Waste Management: a case study in the city of Rio de Janeiro -- Chapter 12. Unsustainable management of Plastic Wastes in India: A threat to global warming and climate change -- Chapter 14. Assessment of public acceptance of the establishment of a recycling plant in Salfit district, Palestine -- Chapter 15. An overview of the technological applicability of plasma gasification process -- Chapter 16. Natural Gas Hydrates: Possible Environmental Issues.
    Abstract: Over the last few decades, unprecedented global population growth has led to increased demand for food and shelter. At the same time, extraction of natural resources beyond the Earth’s resilience capacity has had a devastating effect on ecosystems and environmental health. Furthermore, climate change is having a significant impact in a number of areas, including the global hydrological cycle, ecosystem functioning, coastal vulnerability, forest ecology, food security, and agricultural sustainability. According to the Intergovernmental Panel on Climate Change (IPCC), only immediate and sustained action will prevent climate change causing irreversible and potentially catastrophic damage to our environment. This book presents various scientific views and concepts, research, reviews, and case studies on contemporary environmental issues in changing climate scenarios and highlights different adaptation measures. Increasing awareness of modern-day patterns of climate change, it addresses questions often raised by environmental scientists, researchers, policymakers and general readers. .
    Type of Medium: Online Resource
    Pages: XX, 293 p. 62 illus., 48 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789813295957
    URL: https://doi.org/10.1007/978-981-32-9595-7
    DOI: 10.1007/978-981-32-9595-7
    DDC: 333.7
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    Critical Skills for Environmental Professionals : Putting Knowledge into Practice (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Environment. ; Biotic communities. ; Communication in the environmental sciences. ; Environmental Sciences. ; Ecosystems. ; Environmental Communication.
    Description / Table of Contents: Chapter 1: Introduction -- Chapter 2: Navigating Scientific Literature -- Chapter 3: The Scientific Method in Environmental Science -- Chapter 4: Establishing Cause-Effect Connections -- Chapter 5: Critical Thinking -- Chapter 6: Systems Thinking -- Chapter 7: Interdisciplinary Frameworks -- Chapter 8: Socio-ecological systems: The Human Connection -- Chapter 9: Working Across Scales: Time -- Chapter 10: Working Across Scales: Space -- Chapter 11: Thinking Outside the Box -- Chapter 12: Translating Science: communicating like a professional -- Chapter 13: Ecological Justice.
    Abstract: This textbook focuses on a set of skills-based learning outcomes common among undergraduate environmental programs. It covers critical scientific skills and ways of thinking that bridge the gap between the knowledge-based content of introductory environmental textbooks and the professional skills students of the environment need to succeed in both their academic programs and professional careers. This emphasis on skills is gaining more traction among academic programs across the country as they shift focus from knowledge delivery to learning outcomes and professional competencies. The book features clear methodological frameworks, engaging practice exercises, and a range of assessment case studies suitable for use across academic levels. For introductory levels, this text uses guided practice exercises to expose students to the skills they will need to master. At the capstone level, this text allows students to apply the knowledge they have gained to real-world issues and to evaluate their competency in key programmatic learning outcomes. A detailed answer key with rubrics customized for specific questions and sample answers at various competency levels is available to verified course instructors. Access to these answer key resources can be obtained by contacting the Springer Textook Team at Textbooks@springer.com.
    Type of Medium: Online Resource
    Pages: XV, 188 p. 116 illus., 106 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030285425
    Series Statement: Springer Textbooks in Earth Sciences, Geography and Environment,
    URL: https://doi.org/10.1007/978-3-030-28542-5
    DOI: 10.1007/978-3-030-28542-5
    DDC: 333.7
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    Translating the Paris Agreement into Action in the Pacific (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Environment. ; Renewable energy sources. ; Climatology. ; Sustainability. ; Refuse and refuse disposal. ; Environmental Sciences. ; Renewable Energy. ; Climate Sciences. ; Sustainability. ; Waste Management/Waste Technology.
    Description / Table of Contents: Part 1 Introduction -- Fiji’s Nationally Determined Contributions (NDC) Implementation Roadmap -- Mitigating through renewable energy – an overview of the requirements and the challenges -- Part 2 Mitigation Actions -- Contributions from hydropower – large and small -- Power from biomass- the importance of efficiency and fuel supply logistics -- Bagasse-fired thermal power generation in Fiji -- Waste to Energy from municipal solid wastes – incineration and biogas-based power generation -- Wind power possibilities -- Potential for large-scale solar farms – contribution to avoided emissions -- Biofuels for transportation – a GIS-based resource assessment -- Coconut oil for biodiesel production – a full life cycle analysis of emissions reduction -- Biodiesel production – dealing with the economic challenge -- Biodiesel production – dealing with the economic challenge -- Electricity generation now and later – energy modelling and forecasting -- Part 3 Efficacy of the Roadmap -- Taking stock – an overall assessment of the NDC Implementation Roadmap.
    Abstract: This book provides an insight into how a country contributes to the GHG emissions reductions required to keep global warming within the limits set by the Paris Agreement arrived at COP21 in 2015. It shows what actions are needed for the implementation plan that Fiji will use to satisfy its quota (i.e. its Nationally Determined Contribution or NDC) of the total GHG emissions reductions. It is a primary resource material for those who wish to obtain an understanding of the science behind climate change mitigation. It reveals the behind-the-scenes action that takes place to convert the rhetoric of climate change into the action on the ground that actually reduces the GHG emissions and global warming. The book also presents a critique of methods adopted by nations in meeting their NDCs to emissions reductions as agreed at the Paris Agreement, and suggests improvements.
    Type of Medium: Online Resource
    Pages: XVIII, 323 p. 91 illus., 66 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030302115
    Series Statement: Advances in Global Change Research, 68
    URL: https://doi.org/10.1007/978-3-030-30211-5
    DOI: 10.1007/978-3-030-30211-5
    DDC: 333.7
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    Community and Climate Resilience in the Semi-Arid Tropics : A Journey of Innovation (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Environment. ; Climatology. ; Agriculture. ; Water. ; Hydrology. ; Soil science. ; Geographic information systems. ; Environmental Sciences. ; Climate Sciences. ; Agriculture. ; Water. ; Soil Science. ; Geographical Information System.
    Description / Table of Contents: Chapter 1. Need for Community Empowerment and Climate Resilience in the Semi-Arid Tropics -- Chapter 2. Adarsha Watershed, Kothapally, ICRISAT’s Innovative Journey: Why, How and What? -- Chapter 3. Climate Change Impacts at Benchmark Watershed -- Chapter 4. Integrated Soil Management for Sustained and Higher Productivity -- Chapter 5. Improved Water Balance and Ecosystem Services through Integrated Watershed Development -- Chapter 6. Improved Livelihoods through Sustainable and Diversified Cropping Systems -- Chapter 7. Impacts of Integrated Watershed Development Using Economic Surplus Method -- Chapter 8. Digital Technologies for Assessing Land use, Crop mapping and Irrigation in Community Watersheds -- Chapter 9. Mainstreaming of Women in Watersheds is Must for Enhancing Family Income -- Chapter 10. Increasing incomes and building climate resilience of communities through watershed development -- Chapter 11. Robust Rural Institutions, Governance Are Must for Sustainable Growth in Watersheds -- Chapter 12. Overview, Summary and Way Forward for Enhancing Impacts of Innovative Model.
    Abstract: This book focuses on developing an integrated holistic approach for harnessing the potential of rain-fed agriculture. In this approach, rainwater management through harvesting and recharging the groundwater is used as an entry point activity for increasing the productivity for farmers through enhanced water use efficiency. To provide the holistic and integrated solutions, the approach of consortium through building partnerships with different stakeholders, eg. different research institutions (State, National and International), development departments, eg. Department of Agriculture, Department of Animal Husbandry etc., Non-Government Organizations (NGOs), Farmers Organizations Community-based Organizations (CBOs) along with market linkages through private companies.
    Type of Medium: Online Resource
    Pages: XII, 269 p. 112 illus., 1 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030299187
    URL: https://doi.org/10.1007/978-3-030-29918-7
    DOI: 10.1007/978-3-030-29918-7
    DDC: 333.7
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    Environmental Management : Environmental Issues, Awareness and Abatement (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Environmental management. ; Pollution. ; Environmental monitoring. ; Sustainability. ; Environmental Law. ; Environmental Management. ; Pollution. ; Environmental Monitoring. ; Sustainability. ; Environmental Law.
    Description / Table of Contents: Chapter 1. Management of water resources -- Chapter 2. Air pollution and its abatement -- Chapter 3. Environmental education and environmental impact assessment -- Chapter 4. Environmental acts and legislation -- Chapter 5. Management of Natural Resources. .
    Abstract: In the current age of science and technology, our lives have become dominated by countless scientific and technological innovations without which the earth would be a much poorer place. Life as we know would become absolutely bleak and boring without the inventions and advances being made all over the globe. In fact, scientific inventions, discoveries and innovations have ushered in a dramatic revolution in virtually every sphere of life. But at the same time, the skewed use of technology is at loggerheads with the environment. We, and our environment, now face a number of critical challenges and it is in response to this that we wrote this book to raise awareness for environmental issues and related management aspects. With a primary focus on Environmental Management – the rational reconciliation of man and nature, which involves the judicious exploitation and utilization of natural resources without disturbing the ecosystem’s balance – it will thus help to improve the relationship between man and environment. Moreover, it offers a wealth of ready-to-use material for advanced undergraduate and graduate students of Environment and Water Management. The book systematically addresses a range of key aspects, e.g. scientific principles, methods and ideas, as well as life-long learning skills for students. Further, it provides a solid foundation for applying scientific approaches to environmental problems. .
    Type of Medium: Online Resource
    Pages: XVII, 218 p. 34 illus., 16 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811538131
    URL: https://doi.org/10.1007/978-981-15-3813-1
    DOI: 10.1007/978-981-15-3813-1
    DDC: 333.7
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    Ecosystem Services for Urban Water Security : Concepts and Applications in Sub-Saharan Africa (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Environmental management. ; Water. ; Hydrology. ; Sociology, Urban. ; Environment. ; Pollution. ; Environmental Management. ; Water. ; Urban Sociology. ; Environmental Sciences. ; Pollution.
    Description / Table of Contents: 1. Introduction -- 2. Linking Ecosystem Services to Urban Water Infrastructures and Institutions -- 3. An Operational Approach for Watershed Investments -- 4. Challenges for Water Security in Asmara, Eritrea -- 5. Designing Watershed Investments for Asmara and the Toker Watershed.
    Abstract: The book addresses the challenges of urban water security and adaptive management in Sub-Saharan Africa, exploring and interlinking novel concepts of ecosystems services, watershed investments, and boundary work. Specifically, the book’s goals are to (i) present a conceptual framework for the urban water sector from an ecosystem services perspective, highlighting the specificities of the Sub-Saharan context; (ii) develop an operational approach to designing and assessing the impacts of watershed investments, based on ecosystem services and boundary work; and (iii) test the approach through a case study in Asmara, Eritrea, and discuss the findings and lessons learned that can be applied in other contexts. Through a fully worked out case study, from identification of water challenges and opportunities to spatially explicit modelling, the book offers a sound and accessible, coverage of issues and proposed solutions to better operationalize ecosystem services, watershed investments and boundary work, to promote adaptive management, and achieve water security in the context of rapidly developing cities in Sub-Saharan Africa. The book is an effective tool for capacity building of diverse stakeholders on the urban water sector, including water managers, local and national policy-makers as well as a suitable resource for both undergraduate and post-graduate courses in planning and geography.
    Type of Medium: Online Resource
    Pages: XX, 80 p. 23 illus., 19 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030456665
    Series Statement: SpringerBriefs in Geography,
    URL: https://doi.org/10.1007/978-3-030-45666-5
    DOI: 10.1007/978-3-030-45666-5
    DDC: 333.7
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    Progress and Prospects in the Management of Oxyanion Polluted Aqua Systems (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Environment. ; Environmental Sciences.
    Description / Table of Contents: Oxyanion in Aqua Systems: Friends or Foes -- Ecological Impacts of Oxyanion in Aqua Systems -- Oxyanion in Groundwater System - Prevalence, Dynamics and Management Strategies -- Occurrence and Management of Selenium in Aqua Systems -- Advances in the management of the neglected Oxyanions (Antimoniate, Borates, Carbonates, Molybdate and, Plumbate) in aqua system -- Trends in the Management of Arsenic Contamination in Potable Water -- Prospects of Photocatalysis in the Management of Nitrate Contamination in Potable Water -- Advances in the Microbial Fuel Cells Technology for the Management of Oxyanion -- Managing Oxyanion in Aqua Systems- Calling Microbes to Action -- The Halogen-Oxyanion Derivatives (i.e. bromate chlorate, chlorite and perchlorate) as Contaminants of Concern -- Monitoring and Management of Anions in Polluted Aqua Systems: Case Studies on Nitrate, Chromate, Pertechnetate And Diclofenac -- Removal of Nitrogen Oxyanion (Nitrate) in Constructed Wetlands -- Global Laws and Economic Policies in the Abatement of Oxyanion in Aqua Systems: Challenges and Future Perspectives. .
    Abstract: This book is a compendium of research efforts and findings on the sources, occurrences, hydrochemistry, and several operating variables that influence the presence of oxyanions in aqua system. The content of this book has been designed to provide an insightful account of an array of innovative technologies for the management of the impacts of oxyanions in water, the progress and drawbacks of these technologies and those that have been effectively deployed to transform oxyanions in water to beneficial species. This book further x-rays global laws and economic policies targeted at effectively curtailing the presence of harmful oxyanions in water, challenges facing these policies, and future perspectives on how best to reduce the level of these harmful oxyanions in water to safe limit. The book is relevant to water professionals, policy makers, academics, and research students.
    Type of Medium: Online Resource
    Pages: XV, 403 p. 75 illus., 56 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030707576
    Series Statement: Environmental Contamination Remediation and Management,
    URL: https://doi.org/10.1007/978-3-030-70757-6
    DOI: 10.1007/978-3-030-70757-6
    DDC: 333.7
    Language: English
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    Air Quality Networks : Data Analysis, Calibration & Data Fusion (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Environment. ; Physical geography. ; Environmental monitoring. ; Business information services. ; Environmental Sciences. ; Earth System Sciences. ; Environmental Sciences. ; Environmental Monitoring. ; IT in Business.
    Description / Table of Contents: 1. Future air quality networks -- 2. General data processing techniques -- 3. Fields deployments performances -- 4. Special applications -- 5. Cooperative and regulatory efforts.
    Abstract: This volume offers expert contributions proposing new and recently set scientific standards for smart air quality (AQ) networks data processing, along with results obtained during field deployments of pervasive and mobile systems. The book is divided into 5 main sections; 1) future air quality networks, 2) general data processing techniques, 3) field deployments performances, 4) special applications, and 5) cooperative and regulatory efforts. The authors offer different sources of data for the production of trustworthy insights, including spatio-temporal predictive AQ maps meant to boost citizen awareness, and informed participation in remediation and prevention policies. Readers will learn about the best and most up-to-date practices for measuring and assessing air quality, while also learning about current regulatory statuses regarding air quality technology design and implementation. The book will be of interest to air quality regulatory agencies, citizen science groups, city authorities, and researchers and students working with air quality sensors and geostatistics.
    Type of Medium: Online Resource
    Pages: VII, 178 p. 86 illus., 73 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031084768
    Series Statement: Environmental Informatics and Modeling,
    URL: https://doi.org/10.1007/978-3-031-08476-8
    DOI: 10.1007/978-3-031-08476-8
    DDC: 333.7
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    Socio-economic and Eco-biological Dimensions in Resource use and Conservation : Strategies for Sustainability (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Environment. ; Biotic communities. ; Biodiversity. ; Conservation biology. ; Ecology . ; Environmental Sciences. ; Ecosystems. ; Biodiversity. ; Conservation Biology.
    Description / Table of Contents: Socio-economic and Eco-biological Dimensions in Resource Use and Conservation: Prologue -- Climate Change impacts and implications: an Indian Perspective -- Local Socio-economic dynamics shaping forest ecosystems in Central Himalayas -- Forests resources of Jharkhand, Eastern India: Socio-economic and bio-ecological perspectives -- Traditional Agroforestry Systems of Northeast India -- Studies on Diversity of Macrofungi In the Tropical Moist Sal Forest of Kamrup District, Assam, India -- Exploring synergistic inter linkages among three ecological issues in the aquatic environment -- Carbon Sequestration Potential of trees in Kuvempu University campus forest area, Western Ghats, Karnataka -- Impact of Weather Shock on Food Insecurity: A Study on India -- Livelihood Strategies and Agricultural Practices In Khonoma Village of Nagaland In India: Observations From Field Study -- Socio-economic and Eco-biological Dimensions in Resource Use and Conservation: Epilogue.
    Abstract: This book presents the outcomes of the 2017 national workshop and international conference organized by CEENR of ISEC, Bengaluru and Assam University Silchar. Addressing the threats to biodiversity and sustainable development resulting from the impacts of human induced pressures on ecosystems and global-warming-driven climate change is a major challenge. It requires increased knowledge and an enhanced information base in order to devise local policies to improve the adaptive capacity of vulnerable socio-ecological systems in developing countries. In this context, the book presents research that has the potential to benefit the environment and empower communities. It appeals to researchers investigating diverse aspects of socio-ecological-biological systems to create strategies for resource use, conservation and management to ensure sustainability.
    Type of Medium: Online Resource
    Pages: XI, 553 p. 95 illus., 73 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030324636
    Series Statement: Environmental Science,
    URL: https://doi.org/10.1007/978-3-030-32463-6
    DOI: 10.1007/978-3-030-32463-6
    DDC: 333.7
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    Stewardship of Future Drylands and Climate Change in the Global South : Challenges and Opportunities for the Agenda 2030 (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Environment. ; Sustainability. ; Climatology. ; Agriculture. ; Biotic communities. ; Environmental Sciences. ; Sustainability. ; Climate Sciences. ; Agriculture. ; Ecosystems.
    Description / Table of Contents: Chapter 1 -- The construction and destruction of successful agricultural lands: case study of viticultural areas in Northern Mexico. Chapter 2 -- Pastoralism and achievement of the 2030 Agenda for Sustainable Development: a missing piece of the puzzle. Chapter 3 -- Trends in the use of groundwater in dry lands of Mexico: case of a complex urbanized socio -- ecosystem of the Chihuahua desert. Chapter 4 -- The socio -- ecological systems approach to research the integrated aquifer management in an agricultural dryland in Mexico. Chapter 5 -- Assessment of climate change impact on drought and flood regime using climatological data derived from GLDAS -- 1, GLDAS -- 2, and MERRA -- 2 over semi -- arid zones of northern Mexico: analysis of temporal patterns of precipitation. Chapter 6 -- Understanding Drylands with a transdisciplinary and participatory approach: participatory observatories and the case of RISZA. Chapter 7 -- Sustainable development Goals and drylands. Chapter 8 -- Conservation and Development in the Mapimi Biosphere: a transdisciplinary and participatory project to understand climate change adaptation. Chapter 9 -- Education for sustainable development (ESD): expert net as promoter of transdisciplinarity through the SDGs. Chapter 10 -- The forced modernization of the Altiplano: disruption of the ecosystem function of the dryland zones in San Luis Potosí, Mexico. Chapter 11 -- Sustainable development in modern times: forgotten native communities in northwestern México. Chapter 12 -- Looking at the past to face the challenges for sustainable development in drylands: the protection of the biocultural heritage in the Tehuacán -- Cuicatlán Biosphere Reserve. Chapter 13 -- The Agadir Platform: a tripartite transatlantic cooperation to achieve sustainable Dryland. Chapter 14 -- The Atlas Workshops of Agdz, Morocco: a model region for a scientific -- artistic dialogue. Chapter 15 -- Drylands, aridification and land governance in Latin America: a regional geospatial perspective. Chapter 16 -- Vulnerability to the effects of climate change: coastal watersheds of arid Mexico. Chapter 17 -- Desert experts through time: traditional hunter -- gatherers from Northern Mexico and its implications for resource management and governance. Chapter 18 -- Governing drylands through Environmental Mainstreaming: how to cope with natural resources scarcity and climate change.
    Abstract: This volume integrates a conceptual framework with participatory methodologies to understand the complexities of dryland socio-ecological systems, and to address challenges and opportunities for stewardship of future drylands and climate change in the global south. Through several case studies, the book offers a transdisciplinary and participatory approach to understand the complexity of socio-ecological systems, to co-produce accurate resource management plans for sustained stewardship, and to drive social learning and polycentric governance. This systemic framework permits the study of human-nature interrelationships through time and in particular contexts, with a focus on achieving progress in accordance with the 2030 United Nations Agenda for Sustainable Development. The book is divided into four main sections: 1) drylands and socio-ecological systems, 2) transdisciplinarity in drylands, 3) interculturality in drylands, and 4) the governance of drylands. Expert contributors address topics such as pastoralism and the characteristics of successful agricultural lands, the sustainable development goals and drylands, dryland modernization, and arid land governance with a focus on Mexico. The volume will be of interest to dryland researchers, sustainable development practitioners and policymakers. .
    Type of Medium: Online Resource
    Pages: XXVI, 359 p. 74 illus., 65 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030224646
    Series Statement: Springer Climate,
    URL: https://doi.org/10.1007/978-3-030-22464-6
    DOI: 10.1007/978-3-030-22464-6
    DDC: 333.7
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    How to Store CO2 Underground: Insights from early-mover CCS Projects (2020)
    Cham :Springer International Publishing :
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    Keywords: Environment. ; Cogeneration of electric power and heat. ; Fossil fuels. ; Geology. ; Geophysics. ; Environmental Sciences. ; Fossil Fuel. ; Geology. ; Geophysics.
    Description / Table of Contents: 1. Why we need engineered geological storage of CO2 -- 2. Geological Storage of CO2: Processes, Capacity and Constraints -- 3. CO2 Storage Project Design -- 4. Monitoring Project Performance and Site Integrity -- 5. Emerging themes and technologies -- References.
    Abstract: This book introduces the scientific basis and engineering practice for CO2 storage, covering topics such as storage capacity, trapping mechanisms, CO2 phase behaviour and flow dynamics, engineering and geomechanics of geological storage, injection well design, and geophysical and geochemical monitoring. It also provides numerous examples from the early mover CCS projects, notably Sleipner and Snøhvit offshore Norway, as well as other pioneering CO2 storage projects.
    Type of Medium: Online Resource
    Pages: XII, 129 p. 82 illus., 77 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030331139
    Series Statement: SpringerBriefs in Earth Sciences,
    URL: https://doi.org/10.1007/978-3-030-33113-9
    DOI: 10.1007/978-3-030-33113-9
    DDC: 333.7
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    Climate Variability and Change in Africa : Perspectives, Experiences and Sustainability (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Environment. ; Climatology. ; Sustainability. ; Water. ; Hydrology. ; Environmental Sciences. ; Climate Sciences. ; Sustainability. ; Water.
    Description / Table of Contents: Overview of climate variability and change in Africa - Perspectives and Experiences -- Integrated assessment of climate change impacts and adaptation in agriculture: The case study of the Wami river sub-basin, Tanzania -- assessing runoff changes in major catchments in Swaziland due to climate change -- change, variability and trend analysis of hydro-climatic time series -- Modelling of surface-groundwater dynamics and climate change impacts in wetland environments -- Impacts of possible climate change and variability on the water resources of southern African - a regional modelling approach -- Framework of best practice for climate change adaptation in Africa: the water – development nexus -- Evaluation of different tillage systems for improved agricultural production in drought prone areas of Malawi -- strengthening horticultural innovation systems for adaptation to effects of urbanization and climate variability in peri-urban areas -- An overview of dynamical down-scaling of global re-analyses for improved climate reconstruction over data sparse regions -- Evaluation of CMIP5 climate models for precipitation projections over the upper blue Nile basin -- Groundwater occurrence, recharge and productivity in tertiary volcanic rocks of Ethiopia and climate change implications -- Relationships among surface water resources in the WR90, WR2005 and WR2012 datasets of south Africa using mean annual runoff of Quaternary catchments -- Africa in a changing climate: redefining Africa's agrarian development policies -- Climate change adaptation research and policy for agriculture in southern Africa (CCARPASA) – evidence from rain-fed systems.
    Abstract: This book presents a comprehensive overview of climate variability and change in Africa, and includes impact assessments and case studies from integration frameworks, with a particular focus on climate, agriculture and water resources. Richly illustrated, the book highlights case studies from western, eastern and southern African region, and explores related development policies. Climate change adaptation research, prediction, and reanalysis are also addressed.
    Type of Medium: Online Resource
    Pages: XXIII, 208 p. 77 illus., 66 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030315436
    Series Statement: Sustainable Development Goals Series,
    URL: https://doi.org/10.1007/978-3-030-31543-6
    DOI: 10.1007/978-3-030-31543-6
    DDC: 333.7
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    Isotopes and the Natural Environment (2020)
    Cham :Springer International Publishing :
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    Keywords: Environment. ; Environmental chemistry. ; Ecology . ; Geochemistry. ; Environmental Sciences. ; Environmental Chemistry. ; Ecology. ; Geochemistry.
    Description / Table of Contents: Preface -- 1. Introduction -- 2. Theory of isotopes -- 3. Analytical methodology -- 4. Applications in the natural environment.
    Abstract: This book provides straightforward and practical information on isotopes applied to a variety of natural sciences. It covers the basics of isotopes and includes detailed examples from a range of natural sciences: ecology, biology, human health, environment and climate, geography, and geology, highlighting their applicability in these fields. It is a must-read for all advanced-undergraduate and graduate students working with isotopes, regardless of the area, and is a very useful one-stop resource for scientists starting in isotope research.
    Type of Medium: Online Resource
    Pages: X, 97 p. 76 illus., 65 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030336523
    Series Statement: Springer Textbooks in Earth Sciences, Geography and Environment,
    URL: https://doi.org/10.1007/978-3-030-33652-3
    DOI: 10.1007/978-3-030-33652-3
    DDC: 333.7
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    Green Neighbourhoods and Eco-gentrification : A Tale of Two Countries (2020)
    Cham :Springer International Publishing :
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    Keywords: Environmental management. ; Sustainability. ; Physical geography. ; Environmental Law. ; Environmental Management. ; Sustainability. ; Physical Geography. ; Environmental Law.
    Abstract: This SpringerBrief brings together a series of studies that delve into the details of French and Israeli green building practices and tell a tale of two countries which deviates considerably from what first impressions might suggest. In-depth data analysis, interviews with stakeholders, and on-the-ground documentation are used to paint a portrait of green neighborhoods in both large and small cities, and to shed light on the diversity of outcomes and the intricate web of interests leading to each one. In the Israeli cases, these dynamics reflect the fact that the private sector has become increasingly dominant in the residential building field, following a decades-long process in which the welfare state has shrunk, and the government has distanced itself from large social programs.The French solution to this dilemma is to mandate the inclusion of subsidized housing within its ecoquartiers, with the declared aim of promoting a diverse 'social mix' of population. Green building has yet to prove itself as a solution for the masses. The sale price of an apartment in a certified green building is significantly higher than what would be justified by either the additional construction costs required to build it, or the energy and water saving potential that can be realized by using it. The tale of two countries presented here suggests that neither the mechanisms of the market nor the proclamations of a welfare state can easily overcome this dilemma. What is needed is a new type of thinking, which can only emerge once the concept of "value" reflects not only the realities of a free-market economy, but also those of a planet which turns out to be distinctly limited in its resources.
    Type of Medium: Online Resource
    Pages: IX, 109 p. 39 illus., 32 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030380366
    Series Statement: SpringerBriefs in Environmental Science,
    URL: https://doi.org/10.1007/978-3-030-38036-6
    DOI: 10.1007/978-3-030-38036-6
    DDC: 333.7
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    Global Climate Change and Environmental Policy : Agriculture Perspectives (2020)
    Singapore :Springer Nature Singapore :
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    Keywords: Environment. ; Sustainability. ; Agriculture. ; Environmental monitoring. ; Environmental health. ; Environmental Sciences. ; Sustainability. ; Agriculture. ; Environmental Monitoring. ; Environmental Health.
    Description / Table of Contents: Chapter 1. Ecological Thinking and Agricultural Sustainability -- Chapter 2. Climate Policy -- Chapter 3. Vulnerability Assessment of the Agro Based Households to Climate Change in the Bundelkhand Region and Suggesting Adaptation Strategies -- Chapter 4. Strategies for Scaling up the Adoption of Organic Farming towards Building Climate Change Resilient Communities -- Chapter 5. Managing Climate Risk in a Major Coffee-Growing Region of Indonesia -- Chapter 6. Global Climate Change and Biofuels Policy: Indian Perspectives -- Chapter 7. Climate Change, Water Resources, and Agriculture: Impacts and Adaptation Measures -- Chapter 8. Mitigating enteric methane emission from livestock through farmer friendly practices -- Chapter 9. Timber Based Mixed Farming/Agroforestry Benefits: A Case Study of Smallholder Farmers in Limpopo Province, South Africa -- Chapter 10. Agriculture, landscape and food value chain transformation as key engines in climate change mitigation: A review of some low carbon policy options and implementation mechanisms -- Chapter 11. Weather Based Automated Agro Advisories: An option to improve sustainability in farming under climate and weather vagaries -- Chapter 12. Climate smart agriculture: Assessment and adaptation strategies in a changing climate -- Chapter 13. Climate Change and Farmers’ Adaptation: Extension and Capacity Building of Small-holder Farmers in Sub-Saharan Africa -- Chapter 14. Climate Change and Gender Policy -- Chapter 15. Climate Change Assessment for Current and Future Agricultural Scenario. .
    Abstract: Global climate change threatens human existence through its potential impact on agriculture and the environment. Agriculture is climate-sensitive, and climate variability and climate change have net negative impact on it. Additionally, the agricultural landscape is affected by monoculture and agro-biodiversity loss, soil fertility depletion and soil loss, competition from biofuel production, crop yield plateaus and invasive species. Nevertheless, the global agricultural production system has to meet the food demands from the growing human population, which is set to exceed 10 billion by 2050. This book discusses the impacts of climate change on agriculture, animal husbandry and rural livelihoods. Further, since agriculture, forestry and other land-use sectors contribute about 10–12 gigatonnes of CO2-equivalent per year, it argues that agricultural policy must dovetail adaptation and mitigation strategies to reduce greenhouse gases emissions. This calls for a reformative and disruptive agricultural strategy like climate-smart agriculture, which can operate at all spatio-temporal scales with few modifications. The book also redefines sustainable agriculture through the lens of climate-smart agriculture in the context of the sustainability of Earth's life- support system and inter- and intra-generational equity. The climate-smart agriculture approach is gaining currency thanks to its inherent positive potential, and its goal to establish an agricultural system which includes "climate-smart food systems", "climate-proof farms", and "climate-smart soils". Climate-smart agriculture provides a pathway to achieve sustainable development goals which focus on poverty reduction, food security, and environmental health. .
    Type of Medium: Online Resource
    Pages: XIII, 435 p. 129 illus., 92 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811395703
    URL: https://doi.org/10.1007/978-981-13-9570-3
    DOI: 10.1007/978-981-13-9570-3
    DDC: 333.7
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    GeomInt—Discontinuities in Geosystems From Lab to Field Scale (2023)
    Cham :Springer Nature Switzerland :
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    Keywords: Environmental management. ; Geotechnical engineering. ; Refuse and refuse disposal. ; Environmental Management. ; Geotechnical Engineering and Applied Earth Sciences. ; Waste Management/Waste Technology.
    Description / Table of Contents: 1. Introduction to GeomInt -- 2. Hydro-mechanical effects in Opalinus clay -- 3. Pressure-driven percolation in Salt Rock -- 4. Stress redistribution -- 5. Virtual reality and computation. .
    Abstract: This is an open access book. In view of growing conflicts over strategic georesources, the use of the geological subsurface in the sense of a regional resource is becoming increasingly important. In this context, georeservoirs are playing an important role for the energy transition not only as a source of energy but also as a storage facility and deep geological disposal for energy waste. The success of the energy transition also depends to a large extent on the efficient and safe use of underground resources. This book complements the previous basic book (GeomInt—Integrity of Host Rocks) with a series of application examples in different rock formations, clay, salt, and crystalline. The methodology developed in GeomInt is used, among others, in the Mont Terri underground research laboratory (Opalinus Clay), in the large borehole test in Springen (salt rock) and in the “Reiche Zeche” teaching and research mine (crystalline rock). In addition, new methodological developments are also taken up in experiments and models and embedded in workflows for geotechnical system analyses. The present book summarizes the results of the collaborative project “GeomInt2: Geomechanical integrity of host and barrier rocks - experiment, modeling and analysis of discontinuities” within the program: Geo Research for Sustainability (GEO: N) of the Federal Ministry of Education and Research (BMBF).
    Type of Medium: Online Resource
    Pages: X, 98 p. 68 illus., 62 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031264931
    Series Statement: SpringerBriefs in Earth System Sciences,
    URL: https://doi.org/10.1007/978-3-031-26493-1
    DOI: 10.1007/978-3-031-26493-1
    DDC: 333.7
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    Life Cycle Engineering and Management of Products : Theory and Practice (2021)
    Cham :Springer International Publishing :
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    Keywords: Environmental management. ; Industrial engineering. ; Production engineering. ; Environmental Management. ; Industrial and Production Engineering.
    Description / Table of Contents: Introduction to Life Cycle Engineering and Management (LCEM) -- Cleaner Production (CP) -- Life Cycle Assessment (LCA) – Definition of Goals and Scope -- LCA – Life Cycle Inventory Analysis and database -- LCA – Product Life Cycle Impact Assessment -- LCA – Interpretation of results -- Theory and practice on Social Life Cycle Assessment -- Product Ecodesign -- Product-Service Systems (PSS) -- Corporate Sustainability - Defining business strategies and models from Circular Economy -- Environmental Management Systems and Environmental Performance Measurement -- Green Supply Chain Management -- Communication and Environmental Labelling.
    Abstract: This book presents the role of life cycle engineering and life cycle management of products and services and their contributions to corporate environmental sustainability and the circular economy. It addresses the main techniques, tools, systems and practices for improving the environmental performance of business products and services throughout their life cycles. The book covers the main topics and concepts related to life cycle engineering and life cycle management applied to the business context. It presents the themes through basic and in-depth theories. In addition, all chapters provide examples of real and hypothetical case studies for discussion and assimilation of theoretical content and its contextualization in the real and practical business scenario. The chapters are complemented by quantitative exercises.
    Type of Medium: Online Resource
    Pages: XIV, 329 p. 101 illus., 68 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030780449
    URL: https://doi.org/10.1007/978-3-030-78044-9
    DOI: 10.1007/978-3-030-78044-9
    DDC: 333.7
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    Fracking and the Environment : A scientific assessment of the environmental risks from hydraulic fracturing and fossil fuels (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Energy policy. ; Energy and state. ; Energy harvesting. ; Environment. ; Power resources. ; Energy Policy, Economics and Management. ; Energy Harvesting. ; Environmental Sciences. ; Natural Resource and Energy Economics.
    Description / Table of Contents: Chapter 1: Introduction: What is Fracking? -- Chapter 2: The History of Oil & Gas Development in the United States -- Chapter 3: Fracking and Air Quality -- Chapter 4: Fracking and Water -- Chapter 5: Effects on Landscapes and Habitats. - Chapter 6: Impacts to Ecosystems and Human Health. - Chapter 7: Fossil Fuels and Climate Change. - Chapter 8: Mitigation and Remediation -- Chapter 9: Balancing Energy, Environment, and Economics.
    Abstract: This book provides a systematic scientific approach to the understanding of hydraulic fracturing (fracking) as a hydrocarbon extraction technology and its impact on the environment. The book addresses research from the past decade to assess how fracking can affect air, water, landscapes and ecosystems, and presents the subject in the context of the history of fracking and shale gas development in the United States, describing what is known and not known about environmental impacts, and the broader implications of fossil energy use, climate change, and technology development. In 9 chapters, the author lays out how and why hydraulic fracturing was developed, what driving forces existed at the beginning of the so-called "shale revolution", how success was achieved, and when and why public acceptance of the technology changed. The intended audience is scientific people who are concerned about fracking, but perhaps do not know all that much about it. It is also intended for lay people who would be interested in understanding the technical details of the process and what effects it might or might not be having on the environment. The book is written at a level that is both understandable and technically correct. A further goal is to give some useful insights even to experienced petroleum geologists and engineers who have been doing fracking for many years. .
    Type of Medium: Online Resource
    Pages: XXII, 279 p. 44 illus., 36 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030591212
    URL: https://doi.org/10.1007/978-3-030-59121-2
    DOI: 10.1007/978-3-030-59121-2
    DDC: 333.7
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    Green Technological Innovation for Sustainable Smart Societies : Post Pandemic Era (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Environmental management. ; Sustainability. ; Artificial intelligence. ; Multimedia systems. ; Environmental engineering. ; Biotechnology. ; Bioremediation. ; Environmental Management. ; Sustainability. ; Artificial Intelligence. ; Multimedia Information Systems. ; Environmental Engineering/Biotechnology.
    Description / Table of Contents: Chapter 1: Smart Cities: Building Sustainable Cities -- Chapter 2: Wearable sensors for smart societies – A survey -- Chapter 3: Post Pandemic EdTech (Educational Technology) on Perspectives of Green Society -- Chapter 4: Towards Sustainability 4.0: A Comprehensive Analysis of Sustainability In Corporate Environment -- Chapter 5: Smart Health Care for Societies: An insight into the Implantable and Wearable Devices for Remote Health Monitoring -- Chapter 6: Power management technique for energy-efficient communication systems in telemedicine -- Chapter 7: Influence of reduced noise levels on human health during Quarantine Lockdown -- Chapter 8: Green Technologies for Handling and Management of Biomedical Waste -- Chapter 9: Patients’ Health Surveillance Model Using IoT and 6G Technology -- Chapter 10: Application of Innovative Eco-friendly energy technology for Sustainable Agricultural Farming -- Chapter 11: Review on Smart Farming and Smart Agriculture for Society: Post-Pandemic Era -- Chapter 12: Applications of Machine Learning and Internet of Things in Agriculture -- Chapter 13: Automation, Modern Tools and Technique for Sustainable Agriculture – An Important Parameter towards Advance Plant Biotechnology -- Chapter 14: Advance Security Schemes for Smart Societies -- Chapter 15: Internet of Things for Environment Protection and Sustainable Living -- Chapter 16: Energy Efficient Smart Cities with Green IoT -- Chapter 17: Materials Development for Energy Storage Applications -- Chapter 18: Integrated Constructed Wetland System for Society -- Index.
    Abstract: This book discusses the innovative and efficient technological solutions for sustainable smart societies in terms of alteration in industrial pollution levels, the effect of reduced carbon emissions, green power management, ecology, and biodiversity, the impact of minimal noise levels and air quality influences on human health. The book is focused on the smart society development using innovative low-cost advanced technology in different areas where the growth in employment and income are driven by public and private investment into such economic activities, infrastructure and assets that allow reduced carbon emissions and pollution, enhanced energy, and resource efficiency and prevention of the loss of biodiversity and ecosystem services. The book also covers the paradigm shift in the sustainable development for the green environment in the post-pandemic era. It emphasizes and facilitates a greater understanding of existing available research i.e., theoretical, methodological, well-established and validated empirical work, associated with the environmental and climate change aspects.
    Type of Medium: Online Resource
    Pages: IX, 423 p. 118 illus., 69 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030732950
    URL: https://doi.org/10.1007/978-3-030-73295-0
    DOI: 10.1007/978-3-030-73295-0
    DDC: 333.7
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    Global Agricultural Production: Resilience to Climate Change (2022)
    Cham :Springer International Publishing :
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    Keywords: Environmental management. ; Food security. ; Climatology. ; Agriculture. ; Sustainability. ; Plant ecology. ; Environmental Management. ; Food Security. ; Climate Sciences. ; Agriculture. ; Sustainability. ; Plant Ecology.
    Description / Table of Contents: Chapter 1. Climate change: An Overview -- Chapter 2. Climate change, agricultural productivity, and food security -- Chapter 3. Climate change and Process Based Soil Modeling -- Chapter 4. Soil microbes and climate smart agriculture -- Chapter 5. Climate Change Impacts on Legumes Crop Production and Adaptation Strategies -- Chapter 6. Cereal crop modeling for food and nutrition security -- Chapter 7. Changing climate scenario: Perspectives of Camelina sativa as low input biofuel and oilseed crop -- Chapter 8. Greenhouse Gas Emissions and Mitigation Strategies in Rice Production Systems -- Chapter 9. Fiber Crops in Changing Climate -- Chapter 10. Estimation of Crop Genetic Coefficients to Simulate Growth and Yield under Changing Climate -- Chapter 11. Climate Change Impacts on Animal Production -- Chapter 12. Climate change and global insect dynamics -- Chapter 13. Sustainable Solutions to Food Insecurity in Nigeria: Perspectives on Irrigation, Crop-Water Productivity, and antecedents -- Chapter 14. Functions of Soil Microbes Under Stress Environment -- Chapter 15. Modeling impacts of climate change and adaptation strategies for cereal crops in Ethiopia -- Chapter 16. Strategies for Mitigating Greenhouse Gas Emissions from Agricultural Ecosystems -- Chapter 17. Environmental and Economic Benefits of Sustainable Sugarcane Initiative and Production Constraints in Pakistan: A Review -- Chapter 18. Modeling Photoperiod Response of Canola under Changing Climate -- Chapter 19. Modeling and Field Based Evaluation of Vernalisation Requirement of Canola for Higher Yield Potential -- Chapter 20. Integrated crop-livestock system: Prospectus for climate change adaptation in Jordan, a case study -- Chapter 21. Impact of Salinity Intrusion Problem in the sediments of paddy field and farmers adaptation initiative: Case Study.
    Abstract: This book covers all aspects related to climate change and agriculture. The book discusses Global Climate Models (GCMs), Coupled Model Intercomparison Project (CMIP) and application of strategic management tool that includes RCP (Representative concentration Pathway), SSP (Shared Socio-economic Pathways) and SPA (Shared climate Policy Assumptions). The book provides information on how climate change, agricultural productivity and food security are interlinked. The impacts of climate change on food security are studied through different climatic drivers e.g., ENSO (El Niño–Southern Oscillation) and SOI (Southern Oscillation Index). These drivers are responsible for the climatic extreme events hence early prediction of these drivers could help to design appropriate adaptive measures for the agriculture sector and could be considered as early warning tools for risk management. Similarly, climate change and process-based soil modeling as well as the role of soil microbes and climate smart agriculture are discussed in this book. Climate change impacts on legume crop production and adaptation strategies are presented, with details about cereal crop modeling, perspectives of Camelina sativa as well as low input biofuel and oilseed crop, greenhouse gases (GHGs) emissions and mitigation strategies.
    Type of Medium: Online Resource
    Pages: VII, 634 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031149733
    URL: https://doi.org/10.1007/978-3-031-14973-3
    DOI: 10.1007/978-3-031-14973-3
    DDC: 333.7
    Language: English
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    Sustainable Development of Water and Environment : Proceedings of the ICSDWE2022 (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Environment. ; Environmental engineering. ; Biotechnology. ; Bioremediation. ; Environmental Sciences. ; Environmental Engineering/Biotechnology.
    Description / Table of Contents: Salinity intrusion in the Vietnamese Mekong Delta, a threat: possible causes, effects on people’s life and production, and temporary solutions and adaptable strategies -- Improved stochastic fractal search algorithm for joint optimal operation of cascade hydropower stations -- Regional Hydrological Model with Global Climate Change of Mean Annual Flows of the Santa River Basin, Applying the Fokker-Planck-Kolmogorov Equation -- Numerical modeling of tsunami in the city of Chorrillos, Lima – Peru -- Evaluation and correction of rainfall forecast by WRF model in the upper reaches of the Yangtze River -- Research and Application of Spatio-temporal Data Model of Water Supply Network Inspection System -- Rapid Development of Online Hydraulic Model Calculation System Based on EPANET Source Code and ArcObjects -- Sprinkler Irrigation Atomization in Relation to Water Surface Tension: A New Laboratory Technique to Investigate Pesticides and Fertilizers Effect on Irrigation Drop Size -- A Volterra Process Model for River Water Temperature -- Solubilization of polycyclic aromatic hydrocarbon mixtures in conventional and gemini surfactant solutions -- A sustainable strategy for petrochemical wastewater treatment via anaerobic co-digestion -- Coagulation/flocculation treatment of carwash wastewater using natural-based material: Asustainable development approach -- Phytoremediation of Textile Wastewater using Water Hyacinth(Eichhornia crassipes): A Sustainable Development Approach -- Synthesis of carbonized bagasse and orange peel wastes as adsorbents for dye removal from aqueous solution: A sustainable approach -- An economic evaluation of integrated desalination systems using Pressurized Water Reactor (PWR) -- Policy of the Republic of Bulgaria in the Field of Natural and Environmental Disasters -- Innovative approaches to reduce the level of environmental pollution from bus transport in Sofia, Bulgaria -- Applications of DSF as Renewable Source Energy Savings in a Small Detached Family House Prototype -- Thermal Engineering Applications in Forest Fire Environments -- Airflow Inside of a Virtual Room Integrating a Vertical Confluent Jets Ventilation System -- Integration selective lithium exchange membrane and diffusion dialysis to recover lithium ions in brine water -- Using thermal desorption technique to treat real field diesel oil-contaminated soils -- Experiment and simulation of mobile underwater dredger fill in- layers technology in open water.
    Abstract: This book of ICSDWE2022 aims to advance the understanding of both the fundamentals of related fields in sustainable development of water and environment and its application to the solution of challenges and problems in engineering. The committee of ICSDWE2022 gathers scholars and experts in related fields both at home and abroad. Under the guidance of the committee, we are confident to the publication of high-quality papers on all aspects of water and environment. The book features graduate-level texts and professional books in related fields. We hope that most scholars, researchers, and engineers can find what they really need in our book.
    Type of Medium: Online Resource
    Pages: X, 370 p. 157 illus., 131 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031075001
    Series Statement: Environmental Science and Engineering,
    URL: https://doi.org/10.1007/978-3-031-07500-1
    DOI: 10.1007/978-3-031-07500-1
    DDC: 333.7
    Language: English
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    Sustainable Agriculture in Egypt : Climate Change Mitigation (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Environmental management. ; Agriculture. ; Bioclimatology. ; Sustainability. ; Biotechnology. ; Environmental Management. ; Agriculture. ; Climate Change Ecology. ; Sustainability. ; Biotechnology.
    Description / Table of Contents: Part I Introduction -- Part II Impact of Climate Change on Crop Production -- Part III Case Studies: Improve Crop Adaptability and Stability to Climate Change -- Part IV Conclusions and Recommendations.
    Abstract: This book presents case studies based on sustainable agriculture in Egypt and how this is effected by climate change. The book is divided into four parts consisting of ten chapters. The first part of the book includes an introduction to the crop productivity, biotechnology and climate change. The second Part consists of two chapters dealing with crop production with a focus on critical periods of crop plants response to stress conditions and the quality of field crops. The third chapter highlights the foundations of crop tolerance to environmental stress and plant traits relevant to stress tolerance. It is devoted to explaining and discussing mechanisms of adaptation to environmental stress conditions and addresses various plant traits related to stress environmental tolerance i.e. phenological, morpho-physiological and biochemical traits which could be used as selection criteria for crops improvement. The third Part consists of five chapters under the theme “Improve Crop Adaptability and Stability to Climate Change and Modern Technology". Chapter 4 highlights the most important strategic food grain crop (wheat). Chapter 5 focuses on the important staple food crop (rice), while Chapter 6 deals with one of the most important food legume crops (faba bean). Chapter 7 and 8 discuss two important oil crops (sesame and sunflower). However, Chapter 9 focuses on cotton as one of the most important fiber crops. These crops are addressed under the following headings: genotype x environment interaction and its relation to climatic change on yield production, performance of genotypes in response to environmental changes, adaptability and yield stability to environmental conditions, additive main effects and multiplicative interaction model, gene action, genetic behavior and heritability for traits related to environmental stress tolerance, role of recent approaches, biotechnology and nanotechnology. Additionally, it is considered how to measure sensitivity of genotypes to environmental stress, and finally the appropriate agricultural practices to mitigate environmental stress on crops under attention. The book ends with Chapter 10 which provides an update of the book topics, present the most important conclusions and recommendations from all chapters. This book has been prepared and supported by recent references and statistics including full-coloured tables and illustrations. The book is written for those interested in crop science, environment, plant breeding, genetics and biotechnology, as well as postgraduate students and researchers in universities and research centres.
    Type of Medium: Online Resource
    Pages: XIII, 320 p. 40 illus., 38 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030818739
    URL: https://doi.org/10.1007/978-3-030-81873-9
    DOI: 10.1007/978-3-030-81873-9
    DDC: 333.7
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    Life Cycle Inventory Analysis : Methods and Data (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Environment. ; Environmental Law. ; Environmental chemistry. ; Environmental management. ; Environmental monitoring. ; Environmental Sciences. ; Environmental Law. ; Environmental Chemistry. ; Environmental Management. ; Environmental Monitoring.
    Description / Table of Contents: Chapter 1. Introduction to "Life Cycle Inventory Analysis" -- Chapter 2. Principles of Life Cycle Inventory Modeling: The Basic Model, Extensions and Conventions -- Chapter 3. Development of Unit Process Datasets -- Chapter 4. Multi-functionality in Life Cycle Inventory Analysis: Approaches and Solutions -- Chapter 5. Data Quality in Life Cycle Inventories -- Chapter 6. Life Cycle Inventory Data and Databases -- Chapter 7. Algorithms of Life Cycle Inventory Analysis -- Chapter 8. Inventory Indicators in Life Cycle Assessment -- Chapter 9. The Link Between Life Cycle Inventory Analysis and Life Cycle Impact Assessment.
    Abstract: Life Cycle Inventory (LCI) Analysis is the second phase in the Life Cycle Assessment (LCA) framework. Since the first attempts to formalize life cycle assessment in the early 1970, life cycle inventory analysis has been a central part. Chapter 1 “Introduction to Life Cycle Inventory Analysis“ discusses the history of inventory analysis from the 1970s through SETAC and the ISO standard. In Chapter 2 “Principles of Life Cycle Inventory Modeling”, the general principles of setting up an LCI model and LCI analysis are described by introducing the core LCI model and extensions that allow addressing reality better. Chapter 3 “Development of Unit Process Datasets” shows that developing unit processes of high quality and transparency is not a trivial task, but is crucial for high-quality LCA studies. Chapter 4 “Multi-functionality in Life Cycle Inventory Analysis: Approaches and Solutions” describes how multi-functional processes can be identified. In Chapter 5 “Data Quality in Life Cycle Inventories”, the quality of data gathered and used in LCI analysis is discussed. State-of-the-art indicators to assess data quality in LCA are described and the fitness for purpose concept is introduced. Chapter 6 “Life Cycle Inventory Data and Databases“ follows up on the topic of LCI data and provides a state-of-the-art description of LCI databases. It describes differences between foreground and background data, recommendations for starting a database, data exchange and quality assurance concepts for databases, as well as the scientific basis of LCI databases. Chapter 7 “Algorithms of Life Cycle Inventory Analysis“ provides the mathematical models underpinning the LCI. Since Heijungs and Suh (2002), this is the first time that this aspect of LCA has been fundamentally presented. In Chapter 8 “Inventory Indicators in Life Cycle Assessment”, the use of LCI data to create aggregated environmental and resource indicators is described. Such indicators include the cumulative energy demand and various water use indicators. Chapter 9 “The Link Between Life Cycle Inventory Analysis and Life Cycle Impact Assessment” uses four examples to discuss the link between LCI analysis and LCIA. A clear and relevant link between these phases is crucial.
    Type of Medium: Online Resource
    Pages: XI, 209 p. 64 illus., 31 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030622701
    Series Statement: LCA Compendium – The Complete World of Life Cycle Assessment,
    URL: https://doi.org/10.1007/978-3-030-62270-1
    DOI: 10.1007/978-3-030-62270-1
    DDC: 333.7
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    Geoecological and Geopolitical Risks for the Oil and Gas Industry in the Arctic : Challenges and threats (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Environmental management. ; Environmental policy. ; Power resources. ; Environmental Management. ; Environmental Policy. ; Natural Resource and Energy Economics.
    Description / Table of Contents: Chapter1. Environmental equity and justice in relation to the development of natural resources in the Arctic -- Chapter2. Geopolitical risks for oil and gas industry in the Arctic Zone of the Russian Federation -- Chapter3. Geoecological risks for oil and gas industry in the Arctic Zone of the Russian Federation (GER analyses and modeling) -- Chapter4. Environmental rating as an indicator of geoecological risk management of Russian oil and gas companies in the Arctic -- Chapter5. Management of geopolitical and geoecological risks as a basis for taking into account national and international interests in the development of natural resources in the Arctic.
    Abstract: This book discusses issues of geoecological (GER) and geopolitical (GPR) risks due to hydrocarbon development of the Arctic. The authors explain the ethical and philosophical foundations of understanding environmental equity and justice in relation to the development of Arctic natural resources and consider various approaches to the moral aspects of making global management decisions in the field of environmental protection and environmental safety. Special attention is paid to analysis of modern geopolitical and geostrategic challenges to the development of the Arctic region. The monograph identifies the key geopolitical factors affecting the sustainable development of the Arctic and analyzes the similarities and differences in the geostrategic positions of the five Arctic states. The authors reveal the need to consider geopolitical challenges in the process of GER analysis for oil and gas development in the Arctic region. The book explores the intersection of the strategic interests for a number of states and describes Russia's inability to ensure environmental safety in the development of Arctic deposits. The book analyzes in detail each type of GER with an emphasis on their potential to lead to additional opportunities and threats, and assesses environmental rating as an indicator of the GER management process of Russian oil and gas companies operating in the Arctic. Although the main focus is on the Russian part of this region, many arguments and conclusions are quite applicable to the entire Arctic region. The consideration of geoecological and geopolitical aspects of the development of Arctic resources with the example of Russian oil and gas companies sheds light on the entire Arctic region, taking into account the interests of all other national and international companies involved in GER and GPR there.
    Type of Medium: Online Resource
    Pages: XX, 156 p. 72 illus., 58 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030959104
    Series Statement: Environmental Pollution, 29
    URL: https://doi.org/10.1007/978-3-030-95910-4
    DOI: 10.1007/978-3-030-95910-4
    DDC: 333.7
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    Carbon Management for Promoting Local Livelihood in the Hindu Kush Himalayan (HKH) Region (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Environment. ; Water. ; Hydrology. ; Geography. ; Sustainability. ; Biotic communities. ; Environmental Sciences. ; Water. ; Regional Geography. ; Sustainability. ; Ecosystems.
    Description / Table of Contents: Chapter1: Managing Carbon Cycle Linkage to Livelihood in HKH Region -- Chapter2: Climate Change Mitigation and Pastoral Livelihood in the Hindu Kush Himalaya Region: Research Focuses, Opportunities and Challenges -- Chapter3: Tracking of Vegetation Carbon Dynamics from 2001 to 2016 by MODIS GPP in HKH region -- Chapter4: Livelihood and Carbon Management by Indigenous People in Southern Himalayas -- Chapter5: Effects of Different Grassland Management Patterns on Soil Properties on the Qinghai-Tibetan Plateau -- Chapter6: Carbon Management of the Livestock Industry in the HKH Region -- Chapter7: Wetlands as a Carbon Sink: Insight into the Himalayan Region -- Chapter8: Milk and Dung Production by Yaks (Poephagus grunniens): Important Products for the Livelihood of the Herders and for Carbon Recycling on the Qinghai-Tibetan Plateau -- Chapter9: Interactive Mechanism of Service Function of Ecosystems and the Effect of Climate Change to the Service Function of Ecosystem in Alpine Grassland of Tibetan Plateau -- Chapter10: Prospects of Biochar for Carbon Sequestration and Livelihood Improvement in the Tibetan Grasslands -- Chapter11: Optimizing the Alpine Grazing System to Improve Carbon Management and Livelihood for Tibetan Herders -- Chapter12: Promoting Artificial Grasslands to Improve Carbon Sequestration and Livelihood of Herders -- Chapter13: Prospects for REDD+ Financing in Promoting Forest Sustainable Management in HKH -- Chapter14: Designing Water Resource Use for Poverty Reduction in the HKH Region: Institutional and Policy Perspectives -- Chapter15: Indigenous Practice in Agro-pastoralism and Carbon Management from a Gender Perspective: A Case from Nepal -- Chapter16: Adaptation by Herders on the Qinghai-Tibetan Plateau in Response to Climate Change and Policy Reforms: the Implications for Carbon Sequestration and Livelihoods -- Chapter17: Developing Linkages for Carbon Sequestration, Livelihoods and Ecosystem Service Provision in Mountain Landscapes--Challenges and Opportunities in the Himalaya Hindu Kush (HKH) Region -- Chapter18: Experience for Future Good Practice and Policy of Combined Carbon Management and Livelihood in HKH Region.
    Abstract: This book contributes to our understanding of linkages between carbon management and local livelihoods by taking stock of the existing evidence and drawing on field experiences in the Hindu Kush Himalayan (HKH) region, an area that provides fresh water to more than 2 billion people and supports the world’s largest population of pastoralists and millions of livestock. This edited volume addresses two main questions: 1. Does carbon management offer livelihood opportunities or present risks, and what are they? 2. Do the attributes of carbon financing alter the nature of livelihood opportunities and risks? Chapters analyze the most pressing deficiencies in understanding carbon storage in both soils and in above ground biomass, and the related social and economic challenges associated with carbon sequestration projects. Chapters deliver insights to both academics from diverse disciplines (natural sciences, social sciences and engineering) and to policy makers. .
    Type of Medium: Online Resource
    Pages: XXI, 347 p. 90 illus., 79 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030205911
    URL: https://doi.org/10.1007/978-3-030-20591-1
    DOI: 10.1007/978-3-030-20591-1
    DDC: 333.7
    Language: English
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    Sustainable Land Management for NEOM Region (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Environmental management. ; Geotechnical engineering. ; Geographic information systems. ; Landscape architecture. ; Environmental Management. ; Geotechnical Engineering and Applied Earth Sciences. ; Geographical Information System. ; Landscape Architecture.
    Description / Table of Contents: Chapter 1. NEOM Region -- Chapter 2. Land Management -- Chapter 3. Physical Characteristics -- Chapter 4. Thematic Maps -- Chapter 5. Drainage Basins -- Chapter 6. Potential Natural Resources -- Chapter 7. Biodiversity -- Chapter 8. Natural Hazards -- Chapter 9. Compatible Land Management -- Chapter 10. Discussion and Conclusion.
    Abstract: This book is the first of its type on NEOM Region, NW of Saudi Arabia. This region has been designated in 2017 to be an international economic hub. However, no studies have been done on this region which occupies several natural resources including remarkable landscape with unique ecological species, ores and water resources. The region is also vulnerable to many aspects of threatening natural hazards. Based on her expertise, namely geomorphological processes, earth sciences, space techniques and natural risk assessment, the author made an initiative to produce this book using advanced tools, specifically satellite images and geo-information system. The book introduces several thematic maps obtained for the first time for NEOM Region. Hence, it represents a scientific guide for land management and urban planning approaches. This book is a very significant document for a variety of readers and researchers including decision makers, land managers and planners, as well as geographers and geologists. In addition, the basic concepts and new approaches attract researchers and academic teams including students, universities and research centers not only in Saudi Arabia, but in different parts of the World. .
    Type of Medium: Online Resource
    Pages: XVIII, 220 p. 57 illus., 46 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030576318
    URL: https://doi.org/10.1007/978-3-030-57631-8
    DOI: 10.1007/978-3-030-57631-8
    DDC: 333.7
    Language: English
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    The Barcelona School of Ecological Economics and Political Ecology : A Companion in Honour of Joan Martinez-Alier (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Environmental economics. ; Power resources. ; Ecology . ; Sustainability. ; Environmental Economics. ; Resource and Environmental Economics. ; Ecology. ; Sustainability.
    Description / Table of Contents: Preface 1. A Grateful appreciation of Joan Martinez-Alier (Herman Daly) -- Preface 2. Memories concerning the career of Joan Martinez-Alier (Laurence Whitehead) -- Preface 3. Conversations with a Catalan polymath (Ramachandra Guha) -- Preface 4. Joan Martinez-Alier and the crisis of civilization, knowledge, and the human species (Victor Toledo) -- Part I. Introduction -- Chapter 1. Justification and scope of the book (Roldan Muradian and Sergio Villamayor-Tomas) -- Chapter 2. A Barcelona school of ecological economics and political ecology (Joan Martinez-Alier) -- Chapter 3. The Barcelona School of ecological economics and political ecology: Building bridges between moving shores (Sergio Villamayor-Tomas, Brototi Roy and Roldan Muradian) -- Part II. Epistemological foundations -- Chapter 4. Metaphysical midwifery and the living legacy of Nicholas Georgescu-Roegen (Katharine N. Farrell) -- Chapter 5. Languages of valuation (Christos Zografos) -- Chapter 6. Post-development: From the critique of development to a pluriverse of alternatives (Federico Demaria, Ashish Kothari, Ariel Salleh, Arturo Escobar and Alberto Acosta) -- Chapter 7. Indigenous and local knowledge and social-ecological systems (Victoria Reyes-García) -- Chapter 8. Degrowth and the Barcelona school (Giorgos Kallis) -- Part III. Social metabolism -- Chapter 9. Agrarian metabolism and socio-ecological Transitions to agroecology Landscapes (Enric Tello and Manuel González de Molina) -- Chapter 10. Multi-scale integrated analysis of societal and ecosystem metabolism (Mario Giampietro) -- Chapter 11. Materials flow analysis in Latin America (Mario Alejandro Pérez-Rincón) -- Chapter 12. Biophysical approaches to food system analysis in Latin America (Jesus Ramos-Martin and Fander Falconí) -- Chapter 13. Ecologically unequal exchange: the renewed interpretation of Latin American debates by the Barcelona School (Beatriz Macchione Saes) -- Chapter 14. Flow/Fund Theory and Rural Livelihoods (Jose Carlos Silva-Macher) -- Chapter 15. Deceitful decoupling: misconceptions of a persistent myth (Alevgul H. Sorman) -- Part IV. Environmental justice conflicts and alternatives -- Chapter 16. Does the social metabolism drive environmental conflicts? (Arnim Scheidel) -- Chapter 17. A critical mapping for researching and acting upon environmental conflicts - the case of the EJAtlas (Daniela Del Bene and Sofia Ávila) -- Chapter 18. The EJAtlas: an unexpected pedagogical tool to teach and learn about environmental social sciences (Mariana Walter, Lena Weber, Leah Temper) -- Chapter 19. Commons regimes at the crossroads: environmental justice movements and commoning (Sergio Villamayor-Tomas, Gustavo García-López and Giacomo D’Alisa) -- Chapter 20. (In)justice in urban greening and green gentrification (Isabelle Anguelovski) -- Chapter 21. From the soil to the soul: Fragments of a theory of economic conflicts (Julien-François Gerber) -- Part V. Science and self-reflected activism -- Chapter 22. Activism Mobilising Science Revisited (Marta Conde and Martí Orta-Martínez) -- Chapter 23. Iberian Anarchism in Environmental History (Santiago Gorostiza) -- Chapter 24. The Barcelona School of ecological economics and social movements for alternative livelihoods (Claudio Cattaneo) -- Chapter 25. The ups and downs of feminist activist research: positional reflections (Sara Mingorria, Rosa Binimelis, Iliana Monterroso, Federica Ravera) -- Chapter 26. From the environmentalism of the poor and the indigenous towards decolonial environmental justice (Brototi Roy and Ksenija Hanaček) -- Part IV. Public policy applications -- Chapter 27. Agrobiodiversity in Mexican Environmental Policy (Nancy Arizpe and Dario Escobar-Moreno) -- Chapter 28. Conventional climate change economics: a way to define the optimal policy? (Jordi Roca and Emilio Padilla) -- Chapter 29. Contribution of global cities to climate-change mitigation overrated (Jeroen C.J.M. van den Bergh) -- Chapter 30. Reconciling Waste Management and ecological economics (Ignasi Puig Ventosa) -- Chapter 31. Work and needs in a finite planet: Reflections from ecological economics (Erik Gómez-Baggethun) -- Chapter 32. Collective action in Ecuadorian Amazonia (Fander Falconía and Julio Oleas) -- Chapter 33. The environmentalism of the paid (Esteve Corbera and Santiago Izquierdo-Tort) -- Index.
    Abstract: In this open access book, ecological economics and political ecology traditions converge into a single academic school. The book constitutes a common ground where multiple and critical voices are expressed, covering a broad scope of urgent matters at the crossroad between society, economy and the natural environment. The manuscripts composing this compendium offer appealing material for both experienced and younger researchers interested in interdisciplinary exchanges in the field of the social environmental sciences. It combines historical accounts with recent theoretical and empirical developments revolving around the interaction between three foundational notions of the Barcelona School: social metabolism, environmental justice and self-reflective science.
    Type of Medium: Online Resource
    Pages: XXV, 400 p. 10 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031225666
    Series Statement: Studies in Ecological Economics, 8
    URL: https://doi.org/10.1007/978-3-031-22566-6
    DOI: 10.1007/978-3-031-22566-6
    DDC: 333.7
    Language: English
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    Strategic Opportunism: What Works in Africa : Twelve Fundamentals for Conservation Success (2023)
    Cham :Springer Nature Switzerland :
    Details
    Keywords: Environment. ; Conservation biology. ; Ecology . ; Biodiversity. ; Biotic communities. ; Environmental Sciences. ; Conservation Biology. ; Ecology. ; Biodiversity. ; Ecosystems.
    Description / Table of Contents: Part l. Background -- Chapter 1. Introduction: Success is Possible -- Chapter 2. Strategic Opportunism: A Pragmatic Approach to Conservation in Africa -- Part ll. Strategic Opportunism in Action: Six Stories of Success -- Chapter 3. Angolan Giant Sable: Rediscovery, Rescue and Recovery -- Chapter 4. Marion Island: Birds, Cats, Mice and Men -- Chapter 5. Gorongosa National Park: Wilderness, War and Wildlife Recovery -- Chapter 6. Overcoming the Taxonomic Impediment: SABONET and the African Plants Initiative -- Chapter 7. Building Biodiversity Knowledge: Mobilising Citizen Science -- Chapter 8. Bridging the Gap: Community Conservancies in Namibia and Zimbabwe -- Part lll: Conclusion -- Chapter 9. Twelve Fundamentals for Conservation Success.
    Abstract: This open access book. provides a synthesis of six projects, across ten countries, each of which have been sustained for two or more decades, and which illustrate how success can be achieved regardless of systems of governance, of a nation’s wealth, or of culture. Detailed narratives are presented on the key personalities that have conceived, conducted and concluded long-term projects: personal stories of vision, failure, frustration and persistence ultimately leading to success. The case studies vary widely in their geography and goals. The single-handed commitment to re-discover the last surviving populations of Giant Sable in the miombo woodlands of central Angola, through the capture, translocation and establishment of robust breeding herds of this magnificent antelope, contrasts with the massively funded, three-decade programme with over one hundred participants that reversed the annual loss to predation by feral cats of 455 000 seabirds from a sub-Antarctic island. Similarly, the foresight of Zimbabwean and Namibian ecologists to place rural communities at the centre of conservation programmes by giving value to wildlife populations and benefits to local people, transformed a land degradation problem to a socio-ecological solution. Across ten countries, building capacity in botanical collection, documentation and herbarium management expanded into a global project to place the knowledge base of Africa’s flora onto an electronic data system accessible to researchers and conservation planners in even the most remote corners of the continent. None of these projects enjoyed immediate results. Each required leadership skills that combined vision, a generosity of spirit, fortuitous timing and the exploitation of unexpected opportunities.
    Type of Medium: Online Resource
    Pages: XVI, 142 p. 46 illus., 32 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031248801
    Series Statement: SpringerBriefs in Environmental Science,
    URL: https://doi.org/10.1007/978-3-031-24880-1
    DOI: 10.1007/978-3-031-24880-1
    DDC: 333.7
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    Sustainable Development of Water and Environment : Proceedings of the ICSDWE2020 (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Environment. ; Water. ; Hydrology. ; Pollution. ; Environmental Sciences. ; Water. ; Pollution.
    Description / Table of Contents: Environmental and Microbiological Assessment of Small-Scale Vegetable Farming Systems irrigated with Wastewater from Upper Balili River, La Trinidad Benguet, Philippines -- The Effects of Sea Level Rise on Salinity and Tidal Flooding Patterns in the Guadiana Estuary -- Effects of climate change on runoff in the Heihe River basin under different sensitivity scenarios -- Comparison of UVA-LED and UVC-LED for water disinfection: Inactivation of Escherichia coli -- Application of Integrated Median Ranked Set Sample and Analytic Hierarchy Process to Enhance Decision Making Process in Environmental Issues-Selecting best Wastewater Collection as a Case Study -- Study on preparation of selective nickel ion exchange membrane by ion-imprinting technique -- Hydraulic ram pump: A practical solution for green energy -- Assessment of the Rudnaya River Geochemical Barriers Water Composition Using Physico-chemical Modeling Method (Dalnegorsk Ore District, Russia) -- An Automatic Method for Drainage Basin Spatial Range Delineation Using DEM -- Impacts of silk garment production on water resources and environment -- Spatial variation of heavy metals contamination in soil at e-waste dismantling site, Buriram Province, Thailand -- Blood lead and cadmium levels of e-waste dismantling workers, Buriram Province, Thailand -- Major microorganisms involved in nitrogen cycle in plateau cold region and its relationship with environmental factors.
    Abstract: This book focuses on water resources and the economic, financial, social and environmental impacts (ICSDWE) of global warming and climate change. It discusses the links between these aspects and presents cutting-edge research, technology, and practice in these fields. The book is a valuable resource for students and researchers at government organizations, academic institutions, and NGOs.
    Type of Medium: Online Resource
    Pages: X, 401 p. 175 illus., 131 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030452636
    Series Statement: Environmental Science,
    URL: https://doi.org/10.1007/978-3-030-45263-6
    DOI: 10.1007/978-3-030-45263-6
    DDC: 333.7
    Language: English
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    Climate Impacts on Agricultural and Natural Resource Sustainability in Africa (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Environment. ; Climatology. ; Sustainability. ; Energy policy. ; Energy and state. ; Agriculture. ; Environmental Sciences. ; Climate Sciences. ; Sustainability. ; Energy Policy, Economics and Management. ; Agriculture.
    Description / Table of Contents: PartI: Introduction -- Chapter1: Agricultural and Natural Resource Sustainability under changing climate in Africa -- PartII: Conservation Agriculture, carbon sequestration and soil and water management -- Chapter2: The Prospects for Conservation Agriculture in Ethiopia -- Chapter3: Land Use Changes and Sustainable Land Management Practices for Soil Carbon Sequestration in Sub-Saharan African Agro-Ecosystems -- Chapter4: Gendered adaptation and coping mechanisms to climate variability in Eastern Uganda rice farming systems -- Chapter5: Integrated soil fertility management based on pigeon pea and cowpea cropping systems influences nitrogen use efficiency, yields and quality of subsequent maize on Alfisols in central Malawi -- Chapter6: A Hydrological Assessment of Wetlands in Lilongwe Peri-Urban Areas: A Case of Njewa, Catchment, Lilongwe Malawi -- PartIII: Sustainable crop/livestock/aquaculture/fish production -- Chapter7: Productivity and chemical composition of maize stover and rice straw under smallholder farming systems intensification in Tanzania -- Chapter8: INTENSIFICATION OF SORGHUM AND PEARL MILLET PRODUCTION IN THE SAHEL-SUDANIAN CLIMATIC ZONES OF MALI -- Chapter9: Impact of climate variability on the use and exposure of pesticides in sugarcane production in Malawi -- Chapter10: Yield and profitability of cotton grown under smallholder organic and conventional cotton farming systems in Meatu District, Tanzania -- Chapter11: In Search of Climate-Smart Feeds: The Potential of Pearl Millet (Pennisetum glaucum, L) to replace maize as an energy feed ingredient in broiler diets in Malawi -- Chapter12: Climate Change and Weather Variability Effects on Cattle Production: Perception of Cattle Keepers in Chikwawa, Malawi -- Chapter13: A cohort study of reproductive performance, associated infections and management factors in Zebu cows from smallholder farms in Malawi -- Chapter14: Effect of dry season supplement feeding of Malawi Zebu cows on reproductive performance, lactation and weight gain in calves -- Chapter15: Effects of concentrate supplementation on the fatty acid composition of fat depots in crossbred goats -- Chapter16: Goat milk quality and possible dairy products from rural households of Tanzania and Malawi under the Farmers-Processor’s partnership -- Chapter17: The need for farmer support and record keeping to enhance sustainable dairy goats breeding in Tanzania and Malawi -- Chapter18: Stratified livestock production and live animal and meat export from Ethiopia: Lessons from the experience of a donor funded project -- Chapter19: Of ‘white elephants’ in fisheries: A conflict resolution model around the usage of climate-smart fish postharvest technologies in Lake Malawi -- PartIV: Policy and Institutions for sustainable agriculture and natural resource management -- Chapter20: Policy and Action for food and climate uncertainties in Malawi -- Chapter21: Need for personal transformations in a changing climate: reflections on environmental change and climate-smart agriculture in Africa -- PartV: Value addition options for smallholder market access and integration -- Chapter22: Between the Sun and Fish are People: A Socio-Economic Study of Solar Dryers for Fish Processing in Malawi -- Chapter23: Profitability of supplementary feeding of indigenous cattle in dry areas of Tanzania -- Chapter24: Integrating smallholder farmers to commodity value chains in sub-Saharan Africa: Challenges, prospects and policy issues -- Chapter25: Economic Rationale of Using African Weaver ants, Oecophylla longinoda Latreille (Hymenoptera : Formicidae) for Sustainable Management of Cashew Pests in Tanzania -- PartVI: Upscaling innovative technologies on smallholder farms -- Chapter26: Determinants of ISFM Technology Adoption and Dis-adoption Among Smallholder Maize Farmers in Central Malawi -- Chapter27: Exploiting arbuscular mycorrhizal fungi-rhizobia-legume symbiosis to increase smallholder farmers’ crop production and resilience under a changing climate -- Chapter28: Availability, access and use of weather and climate information by smallholder farmers in the Kilombero River Catchment, Tanzania -- Chapter29: Gender differentiation in the adoption of climate smart agriculture technologies and level of adaptive capacity to Climate Change in Malawi -- Chapter30: Smallholder farming in Mara and Iringa Regions, Tanzania: Current practices, Constraints and Opportunities -- Chapter31: Impact of Farm Input Subsidies vis-à-vis Climate-Smart Technologies on Maize Productivity: A Tale of Smallholder Farmers in Malawi -- Chapter32: Digital storytelling as an agricultural extension communication tool in smallholder farming and fishing communities in Malawi -- Chapter33: Assessing the role of storytelling presentation in knowledge transfer from climate change projects in Tanzania: The case of the EPINAV programme -- PartVII: Conclusion -- Chapter34: Knowledge gaps and research priorities.
    Abstract: This book discusses knowledge-based sustainable agro-ecological and natural resource management systems and best practices for sustained agricultural productivity and ecosystem resilience for better livelihoods under a changing climate. With a focus on agriculture in Africa, the book assesses innovative technologies for use on smallholder farms, and addresses some of the key Sustainable Development Goals to guide innovative responses and enhanced adaptation methods for coping with climate change. Contributions are based on 'Capacity Building for Managing Climate Change in Malawi' (CABMACC), a five-year program with an overall goal to improve livelihoods and food security through innovative responses and enhanced capacity of adaptation to climate change. Readers will discover more about sustainable crop production, climate smart agriculture, on-farm energy supply from biogas and the potential of soil carbon sequestration in crop-livestock systems. .
    Type of Medium: Online Resource
    Pages: XVIII, 637 p. 123 illus., 98 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030375379
    URL: https://doi.org/10.1007/978-3-030-37537-9
    DOI: 10.1007/978-3-030-37537-9
    DDC: 333.7
    Language: English
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    Ancillary Benefits of Climate Policy : New Theoretical Developments and Empirical Findings (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Environmental economics. ; Environment. ; Finance, Public. ; Environmental management. ; Environmental Economics. ; Environmental Sciences. ; Public Economics. ; Environmental Management.
    Description / Table of Contents: Ancillary Benefits and Development Co-effects -- Conceptual and Theoretical Approaches for the Analysis of Ancillary Benefits -- Ancillary Benefits in Different Sectors and in Adaptation to Climate Change -- Climate Actions in Urban Areas and their Ancillary Benefits. .
    Abstract: This volume presents new developments in the research on ancillary benefits. Twenty years after the influential OECD report on ancillary benefits, the authors discuss theoretical innovations and offer new empirical findings on various ancillary effects in different world regions. Covering topics such as ancillary health effects associated with reduced air pollution, the influence of ancillary benefits on international cooperation on climate protection, co-effects of carbon capture and storage, ancillary effects of adaptation to climate change, multi-criteria decision analysis covering multiple effects of climate protection actions, and the analysis of primary and ancillary effects within an impure public goods framework, it provides starting points for further research on integrated climate policies seeking to address a range of policy objectives simultaneously.
    Type of Medium: Online Resource
    Pages: X, 345 p. 46 illus., 26 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030309787
    Series Statement: Springer Climate,
    URL: https://doi.org/10.1007/978-3-030-30978-7
    DOI: 10.1007/978-3-030-30978-7
    DDC: 333.7
    Language: English
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  • 89
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    ICDSME 2019 : Proceedings of the 1st International Conference on Dam Safety Management and Engineering (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Environmental management. ; Water. ; Hydrology. ; Security systems. ; Environmental economics. ; Financial risk management. ; Pollution. ; Environmental Management. ; Water. ; Security Science and Technology. ; Environmental Economics. ; Risk Management. ; Pollution.
    Description / Table of Contents: Challenges in Preparation and Implementation of Dam Safety Emergency Plan for Hydroelectric Plants in Sarawak -- Optimizing Reservoir Operation Under Changing Climate: A Case Study of Murum-Bakun Hydro Cascade in Sarawak -- Visual Inspection of Penstocks and Water Tunnels for Hydropower Plants in Malaysia -- Sediment yield modeling as sediment management strategies towards sustainability of hydropower reservoirs in Malaysia -- Review on Seismic Hazard Parameters for Design and Construction of Large Dams in Peninsular Malaysia -- Building-Capacity through School-Based Engagement on Dam Safety Program in Cameron Highlands -- Flood hydrograph generation for Kenyir Dam using Hydrological Modeling System -- PMP Driven Probable Maximum Flood for 4 dams in Sungai Perak Hydroelectric scheme.
    Abstract: This book presents peer-reviewed articles from the 1st International Conference on Dam Safety Management and Engineering (ICDSME 2019), organized by the Malaysian National Committee on Large Dams (MYCOLD), Tenaga Nasional Berhad (TNB), Department of Irrigation and Drainage (DID) and Universiti Tenaga Nasional (UNITEN). With the theme “resilient dams for resilient communities,” the conference highlighted the latest developments in the area and provided a platform for researchers and professionals to exchange ideas and to address dam safety and engineering issues with the environment in mind. The topics covered included, but was not limited to, best practices in dam safety, reservoir management, dam health monitoring, risk assessment, emergency management and sustainable dams.
    Type of Medium: Online Resource
    Pages: XIX, 683 p. 371 illus., 328 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811519710
    Series Statement: Water Resources Development and Management,
    URL: https://doi.org/10.1007/978-981-15-1971-0
    DOI: 10.1007/978-981-15-1971-0
    DDC: 333.7
    Language: English
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    Investigation and Assessment Technology for Typical Groundwater-contaminated Sites and Application Cases (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Environmental management. ; Pollution. ; Environmental monitoring. ; Environmental Management. ; Pollution. ; Environmental Monitoring.
    Description / Table of Contents: Introduction -- Environmental background investigation of groundwater contamination sites -- Rating and evaluation of pollution source intensity for typical groundwater contamination sites -- Risk assessment of groundwater contamination sites -- Application case.
    Abstract: This book introduces readers to environmental background investigation, pollution source intensity evaluation and risk assessment approaches used at three main types of groundwater-contaminated sites: municipal domestic waste landfills, hazardous waste landfills and oil-contaminated sites. In addition, typical contaminated sites throughout China are examined to demonstrate how these approaches can be applied for their investigation, assessment and restoration. By reading this book, readers will gain a deeper understanding of the restoration and management of typical groundwater-contaminated sites.
    Type of Medium: Online Resource
    Pages: XI, 388 p. 145 illus., 115 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811528453
    URL: https://doi.org/10.1007/978-981-15-2845-3
    DOI: 10.1007/978-981-15-2845-3
    DDC: 333.7
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  • 91
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    Resource Use and Sustainability of Orang Asli : Indigenous Communities in Peninsular Malaysia (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Environmental management. ; Anthropology. ; Ethnology. ; Biodiversity. ; Sustainability. ; Environmental Management. ; Anthropology. ; Ethnology. ; Biodiversity. ; Sustainability.
    Description / Table of Contents: Preface -- Acknowledgements -- Part I: Social and Demography -- Chapter 1. A Journey of Incremental Steps for the Orang Asli (Albert Abee) -- Chapter 2. Orang Asli Anecdotal Reflections (Albert Abee) -- Chapter 3. The Importance of Forest Resources as a Source of income for the Orang Asli of Kampung Sungai Berua, Hulu Terengganu, Malaysia (Norhayati Ab Manaf, Ramle Abdullah, Jumadil Saputra, Nurul Faezah Noor Azizan & Hairul Nizam Mohd Khori) -- Chapter 4. Spending Habits of the Orang Asli in Kampung Sungai Berua, Hulu Terengganu, Malaysia (Norhayati Ab Manaf, Ramle Abdullah, Jumadil Saputra & Nurul Faezah Noor Azizan) -- Part II: Sustainability of Resource Use -- Chapter 5. Sustainable Utilisation of Forest Plant Resources by the Bateq and Semoq Beri Tribes in Kelantan and Terengganu, Peninsular Malaysia (Jamilah Mohd Salim, Suzairi Zakaria, Muhamad Razali Salam & Mohd Tajuddin Abdullah) -- Chapter 6. A Study on Wild Mushrooms Utilised for Food and Medicine by Orang Asli Communities at Sungai Berua, Terengganu (Harizah Nadiah Hamzah & Aqilah Mohammad) -- Chapter 7. Ethnoichtyological Survey among the Orang Asli in Tasik Kenyir, Terengganu (Muhammad Syamsul Aznan Ariffin, Faizah Mohamad Shaharom & Mohd Tajuddin Abdullah) -- Chapter 8. Ethnozoological Survey among the Orang Asli in Terengganu, Peninsular Malaysia (Candyrilla Vera Bartholomew, Nurul Faezah Noor Azizan, Mohd Tajuddin Abdullah & Ramle Abdullah) -- Chapter 9. Ethnozoology, Wildlife Utilisation and Hunting Practices by Semoq Beri Tribes in Pahang (Muhammad Abu Bakar Abdul Latiff, Mohd Ayub Afiqah, Zahari Fatin, Othman Nursyuhada, Hidayah Haris, Mohd Faudzir Najmuddin, and Badrul Munir Md-Zain) -- Chapter 10. Wildlife Hunting Practices by The Indigenous People of Terengganu, Peninsular Malaysia (Candyrilla Vera Bartholomew, Mahfuzatul Izyan Zainir, Nor Zalipah Mohamed, Mohd Hasdi Husin & Mohd Tajuddin Abdullah) -- Part III: Governance, Administration and Management -- Chapter 11. A multidisciplinary account of the Orang Asli in Peninsular Malaysia (Abu Talib Ahmad, Mahani Musa, Nazarudin Zainun, Nasha Rodziadi Khaw, Hisham Atan Edinur, and Geoffrey Keith Chambers) -- Chapter 12. Orang Asli Health and Mortality in Hulu Terengganu, Malaysia (Muhammad Fuad Abdullah, Azmah Othman, Rohana Jani, Juli Edo, and Mohd Tajuddin Abdullah) -- Chapter 13. Socio-economic Development and Sustainable Livelihood of the Orang Asli (Muhammad Fuad Abdullah, Azmah Othman, Rohana Jani, Juli Edo, Mohd Tajuddin Abdullah) -- Chapter 14. Ecological Balance Towards Sustainable Index of Tasik Kenyir (Muhamad Na’eim Abdul Rahman, Muhamad Safiih Lola, Mohd Noor Afiq Ramlee, Muhammad Syamsul Aznan Ariffin & Mohd Tajuddin Abdullah) -- Chapter 15. Redefine Green Economy and Sustainable Development: A Trade-Off Analysis Approach on Tasik Kenyir, Terengganu, Malaysia (Mohd Noor Afiq Ramlee, Muhamad Safiih Lola, Muhamad Na’eim Abdul Rahman, Mohd Fadli Hussin, Muhammad Syamsul Aznan Ariffin & Candyrilla Vera Bartholomew & Mohd Tajuddin Abdullah) -- Index.
    Abstract: Comprising of ­18 sub-ethnic groups the indigenous communities, or better known as the Orang Asli, located in the Peninsular Malaysia, is a unique community in terms of their culture, lifestyle, and heritage. The life of the Orang Asli, popularly referred to as the Forest People, is highly intertwined with forest resources which makes the community a great source of information and traditional knowledge, particularly in the use of medicinal plants. This book covers three important issues to explain and gain insights into the sustainability of the Orang Asli: Social and demographics Sustainability of resource use Governance, administration and management The book presents research to help bridge the gaps and provides a baseline reference for further research regarding the sustainability of the Orang Asli. This book is intended for researchers and graduate students to help gain an understanding of the Orang Asli. By highlighting the plight of Orang Asli the authors hope that this community will be recognised and become a part of society. More research is required to help the 178,197 Orang Asli achieve the sustainable development goals for their community in the Peninsular Malaysia.
    Type of Medium: Online Resource
    Pages: XIX, 243 p. 103 illus., 66 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030649616
    URL: https://doi.org/10.1007/978-3-030-64961-6
    DOI: 10.1007/978-3-030-64961-6
    DDC: 333.7
    Language: English
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    Political Economy of China’s Climate Policy (2022)
    Singapore :Springer Nature Singapore :
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    Keywords: Environment. ; Physical geography. ; Environmental sciences Social aspects. ; Environmental Sciences. ; Earth System Sciences. ; Environmental Social Sciences.
    Description / Table of Contents: An Economic Analysis of China's Climate Policy -- China’s Balance of Emissions Embodied in Trade: Approaches to Measurement and Allocating International Responsibility -- Low Carbon Transformation -- Adapting to the Carrying Capacity, Ensuring Ecological Safety -- Post-Paris Process: A Transformational Breakthrough Is Still Needed.
    Abstract: This book covers major advances in China’s climate policy over the past decade and presents theoretical approaches to climate justice and low-carbon transformation from a Chinese perspective. It analyzes the political economy of China’s climate policy, and subsequently addresses the following major aspects: carbon emissions and human rights, equity and carbon budgets, economic analysis of low-carbon transformation, economics of adaptation to climate change, and international climate regime building. .
    Type of Medium: Online Resource
    Pages: XV, 324 p. 39 illus., 7 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811687891
    Series Statement: Research Series on the Chinese Dream and China’s Development Path,
    URL: https://doi.org/10.1007/978-981-16-8789-1
    DOI: 10.1007/978-981-16-8789-1
    DDC: 333.7
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    Water and Life in Tonle Sap Lake (2022)
    Singapore :Springer Nature Singapore :
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    Keywords: Environmental management. ; Pollution. ; Water. ; Hydrology. ; Environment. ; Environmental Management. ; Pollution. ; Water. ; Environmental Sciences.
    Description / Table of Contents: Chapter1. Introduction -- Chapter 2. Lake and Livelihoods: Threats to Their Sustainability -- Chapter 3. Fish Resources: Its Importance and Challenges -- Chapter 4. Governance and Human–Nature Relation -- Chapter 5. Zoning and Its Impacts on Governance -- Chapter 6. Climate and Rainfall -- Chapter 7. Inundation and Water Surface Temperature: Satellite-Based Observation -- Chapter 8. Hydrology of the Inflow River Basins -- Chapter 9. Groundwater and Surface Water Exchange in the Lake Basin -- Chapter 10. Improvement of a Hydrological Model Performance by Satellite Rainfall Product -- Chapter 11. Flood Pulse and Water Level -- Chapter 12. Discharge Measurement and Hydraulic Characteristics in the Tonle Sap River -- Chapter 13. Mathematics and Numerics of a Two-Dimensional Local Inertial Equation -- Chapter 14. Numerical Simulation of Hydrodynamics Using the Two-Dimensional Local Inertial Equation -- Chapter 15. Hydrodynamic Properties Characterized by Two-Dimensional Hydraulic Simulation -- Chapter 16. Flow Regime of a Floating Village Using a Three-Dimensional Hydraulic Model -- Chapter 17. Sediment and Suspended Solids: Spatiotemporal Dynamics -- Chapter 18. Total Suspended Solid Dynamics Revealed by Long-term Satellite Image Analysis -- Chapter 19. Sediment Resuspension and its Relation to Flood Pulse -- Chapter 20. Sediment Loads from Tonle Sap Lake Tributaries -- Chapter 21. Physico-Chemical Properties of Suspended Solids and Sediment -- Chapter 22. Basin-wide Distribution of Water Quality -- Chapter 23. Basic Physicochemical Water Quality—Spatiotemporal Distribution -- Chapter 24. Nutrient Availability and Phosphorus Dynamics -- Chapter 25. Phosphorus Dynamics—Modeling and Simulation -- Chapter 26. Chemistry of Groundwater in the Floodplain -- Chapter 27. Bacterial Communities: Their Dynamics and Interactions with Physicochemical Factors -- Chapter 28. Microcystin Production and Oxidative Stress -- Chapter 29. Multidrug-Resistant Bacteria -- Chapter 30. Antibiotic Resistance of Intestinal Bacteria -- Chapter 31. Primary Production -- Chapter 32. Flooded Forests -- Chapter 33. Aquatic Fauna and Aquaculture -- Chapter 34. Waterbirds -- Chapter 35. Chemical Analysis of Heavy Metals and Pesticides: Pretreatment -- Chapter 36. Heavy Metals -- Chapter 37. Residual Pesticides -- Chapter 38. Heavy Metal Accumulation in Fish -- Chapter 39. Pesticide Residues in Vegetables from Provinces around Tonle Sap Lake -- Chapter 40. Water Use, Sanitation, and Health Conditions in Villages on/around the Lake -- Chapter 41. Health Risk Assessment of a Floating Village Based on a Three-Dimensional Hydraulic Model -- Chapter 42. Virus Removal by Poly Aluminum Chloride and Calcium Hypochlorite -- Chapter 43. Impact of Climate Change on the Hydrological Regime of Tonle Sap Lake -- Chapter 44. Projection of Land Use and Land Cover in the Lake Basin -- Chapter 45. Permissible Phosphorus Load -- Chapter 46. Effects of Environmental Factors on Eutrophication -- Chapter 47. Application of a Sorbent Derived from Lake Sediment and Bivalve Shells for Phosphorus Removal -- Chapter 48. Management of Flooded Forests and Fish Resources -- Chapter 49. Transdisciplinary Research Collaboration for Environmental Conservation -- Chapter 50. Recommendations for Further Research and Environmental Management.
    Abstract: This book describes the water, wildlife, and livelihood of Tonle Sap Lake and its basin in Cambodia, the largest freshwater lake in Southeast Asia. It comprehensively elucidates the processes underlying the dynamic, productive, and unique ecosystem, covering the major environmental and administrative components such as climate, water flow and storage, sediment, nutrient, flora, fauna, floating villages, management, and governance. Anthropogenic impacts including climate change on the lake are also highlighted. This book serves as a guidebook to multiple audiences, including professionals and academicians. It is beneficial to the university students and lecturers, researchers, freelancers, and policymakers in analyzing, interpreting, and taking action for the environmental conservation of the lake environment. In addition, this is the first comprehensive book on evidence-based research and policy-relevant experience and knowledge about Tonle Sap Lake. For instance, the content will assist the policymakers and researchers in setting management policies and practices, especially for large shallow lakes and developing countries. It can also be used as a textbook in environmental science and engineering at undergraduate and graduate levels worldwide in understanding and synthesizing new research directions relevant to the water environment.
    Type of Medium: Online Resource
    Pages: XVIII, 525 p. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811666322
    URL: https://doi.org/10.1007/978-981-16-6632-2
    DOI: 10.1007/978-981-16-6632-2
    DDC: 333.7
    Language: English
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    Handbook of Climate Services (2020)
    Cham :Springer International Publishing :
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    Keywords: Environment. ; Environmental monitoring. ; Environmental Law. ; Environmental Sciences. ; Environmental Monitoring. ; Environmental Law.
    Description / Table of Contents: Part 1: Principles and Applications of Climate Services -- Introducing Climate Services and their Applications -- A Coastal Climate Service Framework for Community-based Adaptation to Rising Sea-levels -- Nitrous Oxide Emissions from Agricultural Farms and Its Contribution to Global Warming -- Part 2: Case Studies on Climate Services -- Climatological Global Solar UV Index: Measurement and Health Issues in Malta -- Climate Services for Climate Resilient Planning of Natural and Cultural Heritage -- Serbian Experiences -- Food Security in the Face of a Climate Change at Kafa Biosphere Reserve, Ethiopia -- Climate Information Services and their Potential on Adaptation and Mitigation: Experiences from Flood Affected Regions in Bangladesh.
    Abstract: This book explores climate services, including projections, descriptive information, analyses, assessments, and an overview of current trends. Due to the pressures now being put on the world’s climate, it is vital to gather and share reliable climate observation and projection data, which may be tailored for use by different groups. In other words, it is essential to offer climate services. But despite the growth in the use of these services, there are very few specialist publications on this topic. This book addresses that need. Apart from presenting studies and the results of research projects, the book also offers an overview of the wide range of means available for providing and using climate services. In addition, it features case studies that provide illustrative and inspiring examples of how climate services can be optimally deployed.
    Type of Medium: Online Resource
    Pages: IX, 519 p. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030368753
    Series Statement: Climate Change Management,
    URL: https://doi.org/10.1007/978-3-030-36875-3
    DOI: 10.1007/978-3-030-36875-3
    DDC: 333.7
    Language: English
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    Climate Change Research, Policy and Actions in Indonesia : Science, Adaptation and Mitigation (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Environment. ; Climatology. ; Physical geography. ; Sustainability. ; Human geography. ; Environmental Sciences. ; Climate Sciences. ; Physical Geography. ; Sustainability. ; Human Geography.
    Description / Table of Contents: Foreword -- Preface -- Introduction -- Part 1 Introduction / Overview -- Part 2 Climate change adaptation -- Part 3. Climate change mitigation -- Glossary. .
    Abstract: This edited volume reviews the latest advances in policies and actions in understanding the science, impacts and management of climate change in Indonesia. Indonesia is one of the most vulnerable countries to climate change due to its geographical, physical, and social-economic situations. There are many initiatives to understand and deal with the impacts in the country. The national government has issued key guiding policies for climate change. International agencies together with local stakeholders are working on strengthening the capacity in the policy formulations and implement actions to build community resilience. Universities are conducting research on climate change related at different scales. Cities and local governments are implementing innovations in adapting to the impacts of climate change and transiting toward green economy. This book summarizes and discusses the state-of-the-art regarding climate change in Indonesia including adaptation and mitigation measures. The primary readership of the book includes policy makers, scientists and practitioners of climate change actions in Indonesia and other countries facing similar challenges. Chapter “Carbon Stocks from Peat Swamp Forest and Oil Palm Plantation in Central Kalimantan, Indonesia” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Type of Medium: Online Resource
    Pages: VIII, 328 p. 47 illus., 41 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030555368
    Series Statement: Springer Climate,
    URL: https://doi.org/10.1007/978-3-030-55536-8
    DOI: 10.1007/978-3-030-55536-8
    DDC: 333.7
    Language: English
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    Measuring Emission of Agricultural Greenhouse Gases and Developing Mitigation Options using Nuclear and Related Techniques : Applications of Nuclear Techniques for GHGs (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Environment. ; Climatology. ; Agriculture. ; Measurement. ; Measuring instruments. ; Applied ecology. ; Soil science. ; Environmental Sciences. ; Climate Sciences. ; Agriculture. ; Measurement Science and Instrumentation. ; Applied Ecology. ; Soil Science.
    Description / Table of Contents: Foreword -- Chapter 1 Introduction -- Chapter 2 Methodology for greenhouse gas emission measurements using non-isotopic techniques -- Chapter 3 Automated laboratory and field techniques to determine GHG emissions -- Chapter 4 Micrometeorological methods -- Chapter 5 Direct and indirect effects of soil fauna, fungi and plants on greenhouse gas fluxes -- Chapter 6 Methane emissions from ruminants -- Chapter 7 Isotopic techniques to measure N2 and pathways of greenhouse gases -- Chapter 8 Climate-smart agriculture practices for greenhouse gas mitigation -- Bibliography -- Index.
    Abstract: This open access book is an outcome of the collaboration between the Soil and Water Management & Crop Nutrition Section, Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture, Department of Nuclear Sciences and Applications, International Atomic Energy Agency (IAEA), Vienna, Austria, and the German Science Foundation research unit DASIM (Denitrification in Agricultural Soils: Integrated control and Modelling at various scales) and other institutes. It presents protocols, methodologies and standard operating procedures (SOPs) for measuring GHGs from different agroecosystems and animals using isotopic and related techniques that can also be used to validate climate-smart agricultural practices to mitigate GHGs. The material featured is useful for beginners in the field wanting an overview of the current methodologies, but also for experts who need hands-on descriptions of said methodologies. The book is written in form of a monograph and consists of eight chapters. .
    Type of Medium: Online Resource
    Pages: XLVI, 337 p. 109 illus., 83 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030553968
    URL: https://doi.org/10.1007/978-3-030-55396-8
    DOI: 10.1007/978-3-030-55396-8
    DDC: 333.7
    Language: English
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  • 97
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    The Earth’s Human Carrying Capacity : Limitations Assessed, Solutions Proposed (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Environment. ; Environmental management. ; Sustainability. ; Food security. ; Environmental Sciences. ; Environmental Management. ; Sustainability. ; Food Security.
    Description / Table of Contents: Chapter1 -- Earth’s Human Carrying Capacity: The Basics -- Chapter2 -- Water: A Limit On Our Earth’s Carrying Capacity -- Chapter3 -- Food Security/Insecurity, Food Systems -- Chapter4 -- Impact of Global Warming/Climate Change On Food Security 2020 -- Chapter 5 -- Sanitation: Waste Generation/Capture/Disposal Status 2020 -- Chapter6 -- Access To Natural Resources Not Water Or Food 2020 -- Chapter7 -- Global Warming And Water 2050: More People, Yes; Less Ice, Yes; More Water, Yes; More Fresh Water, Probably; More Accessible Fresh Water -- Chapter8 -- Food 2050 - More Mouths To Feed: Food Availability and Access -- Chapter9.-Sanitation 2050 -- Chapter10 -- Natural Resources Beyond Water And Food 2020 To 2050 -- Chapter11 -- Economic Realities in 2020 Populations: What do they Portend for 2050? 2100?
    Abstract: This book focuses on the Earth’s carrying capacity to service the needs of its human populations as well as preserve the ecosystems that provide natural resources that sustain life and support human activities in 2020 and later in the century (2050 and beyond). It addresses the two principal factors that challenge the limits of the carrying capacity: growing populations/demographic moves and global warming/climate change. It also covers the effects that these factors have on water availability, food security, sanitation and natural resources. The status of these basic needs that sustain life and societal activities with respect to population increases and global warming driven climate changes are discussed on two time frames. One with respect to the 2020 and the other with measured and computer guided projected future impacts later as the century progresses to 2050 and later, Attention is given to Africa, Asia, and somewhat for South America because of their projected increases in population. The purpose of the book is to provide those in decision-making roles and those that advise them with a sound set of facts and figures to think about to support their decisions/actions. A secondary purpose is to present data that stresses the need to act now, firmly and with investment to plan to adapt to changing conditions rather than wait until forced to do so. The book also discusses how the COVID-19 pandemic has affected the world’s societies and how they have reacted. The book will be of use to students in first/second year of college/university programs in Environmental Sciences/Studies, demographics, and ancillary fields such as agriculture science, urban/land use planners, political science, public health, and consultants at academic and professional levels.
    Type of Medium: Online Resource
    Pages: XIII, 154 p. 3 illus., 2 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030734763
    URL: https://doi.org/10.1007/978-3-030-73476-3
    DOI: 10.1007/978-3-030-73476-3
    DDC: 333.7
    Language: English
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  • 98
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    Online Resource
    Bangladesh II: Climate Change Impacts, Mitigation and Adaptation in Developing Countries (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Environment. ; Climatology. ; Water. ; Hydrology. ; Environmental Sciences. ; Climate Sciences. ; Water.
    Description / Table of Contents: Chapter1.Climate Change Impact on Life and Livelihoods in Bangladesh -- Chapter 2. Climate change impact on the reduction of forest in Bangladesh -- Chapter3. Climate change impacts on the coastal zones of Bangladesh -- Chapter4. Mitigation strategies of Coastal People to Climate Change and Vulnerabilities -- Chapter5. Climate Change Impact on Groundwater Based Irrigation in Bangladesh -- Chapter6. Climate Smart Resilience for Vulnerable Communities in Bangladesh.
    Abstract: This volume develops a framework for disaster and climate risk resilient livelihood system in Bangladesh using a policy oriented approach. It highlights the possible impacts of climate change on groundwater based irrigation in the country. Climate change is one of biggest challenges to society. It can lead to serious impacts on production, life and environment on a global scale. Higher temperatures and sea level rise will cause flooding and water salinity problems which will bring about negative effects on agriculture and high risks to industry and socio-economic systems in the future. Climate change will lead to many changes in global development and security especially energy, water, food, society, job, diplomacy, culture, economy and trade. The Intergovernmental Panel on Climate Change (IPCC) defines climate change as: “Any change in climate over time, whether due to natural variability or as a result of human activity.” Global climate change has emerged as a key issue in both political and economic arenas. It is an increasingly questioned phenomenon, and progressive national governments around the world have started taking action to respond to these environmental concerns.
    Type of Medium: Online Resource
    Pages: XVI, 478 p. 147 illus., 105 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030719500
    Series Statement: Springer Climate,
    URL: https://doi.org/10.1007/978-3-030-71950-0
    DOI: 10.1007/978-3-030-71950-0
    DDC: 333.7
    Language: English
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  • 99
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    Online Resource
    Integrated Research on Disaster Risks : Contributions from the IRDR Young Scientists Programme (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Environment. ; Human geography. ; Public health. ; Natural disasters. ; Sociology, Urban. ; Environmental Sciences. ; Human Geography. ; Public Health. ; Natural Hazards. ; Urban Sociology.
    Description / Table of Contents: Foreword -- Preface -- Introduction -- Index -- Glossary.
    Abstract: This book is a collection of works written by young scientists involved in the Integrated Disaster Risk Research (IRDR). Integrated Research on Disaster Risk (IRDR) is a decade-long research programme co-sponsored by the International Science Council (merged by International Council for Science (ICSU), the International Social Science Council (ISSC), and the United Nations Office for Disaster Risk Reduction (UNDRR). It is a global, multi-disciplinary approach to dealing with the challenges brought by natural disasters, mitigating their impacts, and improving related policy-making mechanisms. The book examines multidisciplinary research and actions related to disaster risk reduction internationally. The Integrated Research on Disaster Risk (IRDR) Young Scientists programme is: • A sub-programme within IRDR which promotes capacity building of young professionals and encourages them to undertake innovative and need-based research which makes science–policy and science–practice linkages stronger. • IRDR Young Scientists Programme was started in late 2016. Currently, it is a community of 115 young researchers from over 40 countries after 3 batches of application. • IRDR network and partners provide academic advice and training courses, workshops, and programmes for IRDR young scientists. • IRDR young scientists contribute to innovative research in the field of disaster risk reduction and participate in conferences and/or social media as the ambassador of IRDR. The book is of interest to researchers and scholars in the field of governance of sustainability and environmental governance. Postgraduate students will benefit this book within courses on environmental governance, on climate change governance, and on transformation and social change processes. Societal actors in climate change adaptation and other environmental governance fields on local, national, and international levels can benefit from the focus on societally relevant findings in the past 10 years of research on adaptiveness.
    Type of Medium: Online Resource
    Pages: VII, 356 p. 111 illus., 90 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030555634
    Series Statement: Disaster Risk Reduction, Methods, Approaches and Practices,
    URL: https://doi.org/10.1007/978-3-030-55563-4
    DOI: 10.1007/978-3-030-55563-4
    DDC: 333.7
    Language: English
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  • 100
    Online Resource
    Online Resource
    Climate Change in Bangladesh : A Cross-Disciplinary Framework (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Environment. ; Climatology. ; Physical geography. ; Environmental Sciences. ; Climate Sciences. ; Physical Geography.
    Abstract: This book is a comprehensive resource for climate change impacts and scenarios on cross-cutting issues in Bangladesh and other tropical low-lying countries in Asia. The book promotes mitigation and adaptation strategies for learning and innovation to tackle climate change impacts, reduce inequality, as well as include changes in food, energy, health, education, and social protection policies in Bangladesh and Asian low-lying countries. Through several case studies, this book provides a powerful framework for identifying management tools and their applications in environment and governance including; climate change and natural hazards, climate change and energy framework, gender inequality and capacity building, and community participants and the actions needed to protect them. The aim of this book is to provide information to scientists, practitioners, academics, and government and non-government policy-makers to help them better understand the particularities of climate change adaptation and mitigation strategies for cross-cutting issues in Bangladesh. .
    Type of Medium: Online Resource
    Pages: XIII, 234 p. 50 illus., 47 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030758257
    Series Statement: Springer Climate,
    URL: https://doi.org/10.1007/978-3-030-75825-7
    DOI: 10.1007/978-3-030-75825-7
    DDC: 333.7
    Language: English
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