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  • 1
    Online Resource
    Online Resource
    Coronary Artery Disease: Therapeutics and Drug Discovery (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Cardiology. ; Therapeutics. ; Heart Surgery. ; Pharmacology. ; Cardiology. ; Therapeutics. ; Cardiac Surgery.
    Description / Table of Contents: Coronary Artery Disease: From Mechanism to Clinical Practice -- Evidence in guidelines for treatment of coronary artery disease -- Revascularization For Coronary Artery Disease: Principle And Challenges -- Antithrombotic drugs: pharmacology and perspectives -- Lipid modifying drugs: pharmacology and perspectives -- Anti-hypertensive drugs: pharmacology and perspectives -- Pharmaceutical treatment for Heart failure -- Drug discovery for coronary artery disease.
    Abstract: This book provides an overview of the etiology of coronary artery disease and focuses on the main therapies and drug interventions currently available. It highlights drug pharmacology and therapeutic challenges, with a special emphasis on the underlying principles of available therapeutics and the on-going development of drugs for coronary artery disease. The book is divided into eight chapters, the first of which describes the classical mechanism of coronary artery disease and its clinical presentations. Chapter 2 lists the principles of and related evidence on the prevention and treatment of coronary artery disease. This includes diet and lifestyle management, and guidelines for the treatment of acute coronary syndrome and stable coronary artery disease. In turn, Chapter 3 describes revascularization treatments, covering percutaneous coronary interventions, coronary artery bypass grafts and thrombolysis. This chapter also addresses the main therapeutic challenges. The following chapters provide an overview of three major categories of coronary artery disease drugs, which target thrombosis (Chapter 4), lipid metabolism (Chapter 5), and hypertension (Chapter 6). Heart failure constitutes the major health burden in the late stage of coronary artery disease; accordingly, current heart failure therapeutics and related drug pharmacology are described in Chapter 7. In closing, Chapter 8 provides a summary of on-going clinical trials for coronary artery disease drug development and discusses a number of promising areas in which intensive research into new therapeutics is being pursued. Given its scope, the book will be of interest to clinicians, medical students and research scientists, as well as to pharmaceutical professionals who are seeking new therapies and drugs for coronary artery disease and related disorders.
    Type of Medium: Online Resource
    Pages: IX, 339 p. 7 illus., 4 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811525179
    Series Statement: Advances in Experimental Medicine and Biology, 1177
    URL: https://doi.org/10.1007/978-981-15-2517-9
    DOI: 10.1007/978-981-15-2517-9
    DDC: 615
    Language: English
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  • 2
    Online Resource
    Online Resource
    Pediatric Pharmacotherapy (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Pediatrics. ; Pharmacology. ; Pediatrics.
    Description / Table of Contents: Anti-epileptic drugs in pediatrics -- Current and new therapies for Duchenne Muscular Dystrophy -- Lysosomal diseases -- Mitochondriopathies -- Endocrinology thyroid, pituitary, growth stimulant, growth reduction -- Bone disease – bisphosphonates -- Diabetes type 1 and 3 (insulin; sulfonylurea; others) -- Diabetes type 2 (metformin etc.) -- Dermatology – part 1 urticaria, atopic dermatitis -- Dermatology part 2, ichtyosis, psoriasis -- Cardiovascular part 1- catcholamines, inotropic -- Cardiovascular part 2 – antiarhythmica, anti hypertensives -- Nephrology – dialysis -- How to use drugs in obese children and adolescents -- Haematology – CSFs, erythropoietin -- Antiretroviral/HIV -- Clinical pharmacology and pharmacometrics to better understand physiological changes during pregnancy and neonatal life -- Antihelminth treatment -- Inflammatory bowel disease -- Constipation; laxatives -- Psychiatric diseases in children and adolescents -- Oncology – cell reducing agents part 1, part 2, part 3 -- Immunosuppressants – organ transplantation -- Bone marrow/stem cell transplantation -- Narcotic sparing approaches and the shift towards paracetamol in neonatal intensive care -- Disorders of puberty: pharmacotherapeutic strategies for management.
    Abstract: This volume provides readers with the most updated scientific information on the efficacy and safety of medicines for children and adolescents. The book enriches the understanding of pediatric pharmacotherapy for health professionals, regulatory agencies, pharmaceutical companies and learned societies. It contains important information on the pharmacodynamics and pharmacokinetics of drugs. It summarizes the latest investigations on the effects of pharmacological treatments in relation to and dependent on age, gender, fat mass and disease status. Therefore and importantly, this volume reviews the latest data on how pharmacotherapy has to be adjusted and personalized in regards to stages of development and during the pediatric lifespan from neonate through adolescence. In addition, the topic of rare diseases and special challenges for pharmacotherapy will be included and will provide readers with the necessary knowledge to handle complex diseases and treatment strategies especially in relation to pharmacotherapy of rare and orphan diseases.
    Type of Medium: Online Resource
    Pages: VIII, 538 p. 1 illus. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030504946
    Series Statement: Handbook of Experimental Pharmacology, 261
    URL: https://doi.org/10.1007/978-3-030-50494-6
    DOI: 10.1007/978-3-030-50494-6
    DDC: 615
    Language: English
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  • 3
    Online Resource
    Online Resource
    Reactive Oxygen Species : Network Pharmacology and Therapeutic Applications (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Cardiology. ; Neurosciences. ; Clinical biochemistry. ; Pharmacology. ; Cardiology. ; Neuroscience. ; Medical Biochemistry.
    Description / Table of Contents: Part I: ROS Revisited: Changing the Focus from Oxidative Stress and Redox Biology to Redox Medicine -- Demystifying oxidative stress -- Oxidants in Physiological Processes -- Network Medicine-Based Unbiased Disease Modules for Drug and Diagnostic Target Identification in ROSopathies -- Part II Targeting antioxidant responses -- Development of Telintra as an Inhibitor of Glutathione S-Transferase P -- Perspectives on the Clinical Development of NRF2-Targeting Drugs -- Part III: Inhibiting ROS formation and toxification -- NOX Inhibitors: From Bench to Naxibs to Bedside -- Nitric Oxide Synthase Inhibitors into the Clinic at Last -- Xanthine Oxidoreductase Inhibitors -- Monoamine Oxidase Inhibitors: From Classic to New Clinical Approaches -- Inhibition of Myeloperoxidase -- Part IV: Stimulating/substituting ROS -- Effects of Mammalian Thioredoxin Reductase Inhibitors -- Cardiovascular Therapeutic Potential of the Redox Siblings, Nitric Oxide (NO•) and Nitroxyl (HNO), in the Setting of Reactive Oxygen Species Dysregulation -- Tetrahydrobiopterin and Nitric Oxide Synthase Recouplers -- Part V: Repairing ROS damage -- Soluble Guanylate Cyclase Stimulators and Activators – Peter Sander -- Inhibitors of Advanced Glycation End Product (AGE) Formation and Accumulation.
    Abstract: Reactive oxygen species (ROS) have been implicated in almost every human disease phenotype, without much, if any, therapeutic consequence foremost exemplified by the failure of the so-called anti-oxidants. This book is a game changer for the field and many clinical areas such as cardiology and neurology. The term ‘oxidative stress’ is abandoned and replaced with a systems medicine and network pharmacology-based mechanistic approach to disease. The ROS-related drugs discussed here target either ROS- forming or ROS -modifying enzymes for which there is strong clinical evidence. In addition, ROS targets are included as they jointly participate in causal mechanisms of disease. This approach is transforming the ROS field and represents a breakthrough in redox medicine indicating a path to patient benefit. In the coming years more targets and drugs may be discovered, but the approach will remain the same and this book will thus become, and for many years remain, the leading reference for ROSopathies and their treatment by network pharmacology. Chapter "Soluble Guanylate Cyclase Stimulators and Activators" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Type of Medium: Online Resource
    Pages: VIII, 425 p. 70 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030685102
    Series Statement: Handbook of Experimental Pharmacology, 264
    URL: https://doi.org/10.1007/978-3-030-68510-2
    DOI: 10.1007/978-3-030-68510-2
    DDC: 615
    Language: English
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  • 4
    Online Resource
    Online Resource
    Organotypic Models in Drug Development (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Medical genetics. ; Pathology. ; Pharmacology. ; Clinical Genetics. ; Pathology.
    Description / Table of Contents: Inflammatory skin disease models in vitro and in animals – predictability for drug development -- Neural In Vitro Models for Studying Substances Acting on the Central Nervous System -- Quality of commercial tissues Standardised Reconstructed Skin Models in Toxicology and Pharmacology: State of the Art and Future Development -- Human-Derived In Vitro Models Used for Skin Toxicity Testing Under REACh -- Disease Models: Lung models for testing drugs against inflammation and infection -- In Vitro Models of the Blood-Brain Barrier -- How Qualification of 3D Disease Models Cuts the Gordian Knot in Preclinical Drug Development -- The CAM Assay as an Alternative In Vivo Model for Drug Testing -- Organotypic Models in Drug Development “Tumor Models and Cancer Systems Biology for the Investigation of Anticancer Drugs and Resistance Development -- Tissue Engineering for Musculoskeletal Regeneration and Disease Modeling -- Immunocompetent human intestinal models in preclinical drug development -- Engineered Heart Muscle Models in Phenotypic Drug Screens.
    Abstract: This book provides latest findings in organotypic models in drug development and provides the scientific resonance needed in an emerging field of research in disciplines, such as molecular medicine, physiology, and pathophysiology. Today the research on human-based test systems has gained major interest and funding in the EU and the US has increased over the last years. Moreover, so-called 3R (reduce, replace, refine animal experiments) centres have been established worldwide.
    Type of Medium: Online Resource
    Pages: VIII, 323 p. 70 illus., 37 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030700638
    Series Statement: Handbook of Experimental Pharmacology, 265
    URL: https://doi.org/10.1007/978-3-030-70063-8
    DOI: 10.1007/978-3-030-70063-8
    DDC: 615
    Language: English
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  • 5
    Online Resource
    Online Resource
    Vaccination Strategies Against Highly Variable Pathogens (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Diseases. ; Virology. ; Immunology. ; Human physiology. ; Pharmacology. ; Diseases. ; Virology. ; Immunology. ; Human Physiology.
    Description / Table of Contents: Successful Vaccines -- Immunogenicity and Immunodominance in Antibody Responses -- Immunogen Design -- Adjuvants -- Tools to screen vaccines -- Targeting glycans on human pathogens for vaccine design -- BnAbs and highly antigenically variable pathogens.
    Abstract: Vaccines against antigenically stable pathogens, or pathogens that only exist in a limited number of serotypes, have been very successful in the past and have drastically decreased the incidence and lethality of many diseases. However, when it comes to highly variable pathogens or viruses that exist in multiple serotypes, the traditional methods for vaccine development have reached their limits. This volume highlights the development of vaccines against such challenging pathogens. Novel approaches for immunogen design, including structure-guided vaccine development and vaccines targeting glycans, as well as adjuvants and animal models used for testing possible vaccine candidates are outlined and discussed in detail. Given its scope, the book will appeal to scientists in the fields of infectious diseases, microbiology and medicine. .
    Type of Medium: Online Resource
    Pages: VII, 180 p. 16 illus., 15 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030580049
    Series Statement: Current Topics in Microbiology and Immunology, 428
    URL: https://doi.org/10.1007/978-3-030-58004-9
    DOI: 10.1007/978-3-030-58004-9
    DDC: 615
    Language: English
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  • 6
    Online Resource
    Online Resource
    Drug Stability and Chemical Kinetics (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Pharmacology. ; Pharmaceutics.
    Description / Table of Contents: 1 Principles of pharmaceutical analysis in drug stability and chemical kinetics -- 2 Guidelines for drug stability and stability testing -- 3 Chemical kinetics and its applications in drug stability -- 4 Methods and protocols for drug stability studies -- 5 Physical basis of degradation of pharmaceutical products -- 6 Role of microbiological degradation on drug stability -- 7 Role of decomposition on drug stability -- 8 Role of catalysis in drug stability -- 9 Analytical techniques for the assessment of drug stability -- 10 Stability of pharmaceutical products -- 11 Role of kinetic models in drug stability -- 12 Stability studies of vaccines -- 13 Stability studies of proteinous compounds -- 14 Stability studies of extemporaneous pharmaceutical products -- 15 Stability studies of parenteral products -- 16 Stability studies of solid dosage forms.
    Abstract: This book comprehensively reviews drug stability and chemical kinetics: how external factors can influence the stability of drugs, and the reaction rates that trigger these effects. Explaining the important theoretical concepts of drug stability and chemical kinetics, and providing numerous examples in the form of illustrations, tables and calculations, the book helps readers gain a better understanding of the rates of reactions, order of reactions, types of degradation and how to prevent it, as well as types of stability studies. It also offers insights into the importance of the rate at which the drug is degraded and/or decomposed under various external and internal conditions, including temperature, pH, humidity and light. This book is intended for researchers, PhD students and scientists working in the field of pharmacy, pharmacology, pharmaceutical chemistry, medicinal chemistry and biopharmaceutics. .
    Type of Medium: Online Resource
    Pages: XIV, 284 p. 22 illus., 13 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811564260
    URL: https://doi.org/10.1007/978-981-15-6426-0
    DOI: 10.1007/978-981-15-6426-0
    DDC: 615
    Language: English
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  • 7
    Online Resource
    Online Resource
    Handbook of 200 Medicinal Plants : A Comprehensive Review of Their Traditional Medical Uses and Scientific Justifications (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Pharmacy. ; Medicinal chemistry. ; Pharmacology. ; Pharmacy. ; Medicinal Chemistry.
    Description / Table of Contents: Abelmoschus maschatus -- Abrus precatorius -- Abutilon indicum -- Acacia catechu -- Acacia nilotica (A. arabica) -- Achillea millefolium -- Achyranthes aspera -- Aconitum napellus -- Acorus calamus -- Adiantum venustum (Adiantun capillus-veneris) -- Aegle marmelos -- Agrimonia eupatorium.-Alhagi maurorum -- Alkanna tinctoria -- Allium cepa -- Allium sativum -- Aloe vera -- Alpinia galangal -- Alpinia officinarum -- Alstonia scholaris -- Althaea officinalis -- Ammi majus -- Anacardium occidentale -- Anacyclus pyrethrum -- Andrographis paniculata -- Anethum graveolens -- Anthemis nobilis -- Apium graveolens -- Argemone Mexicana -- Aristolochia bracteolata -- Aristolochia fontanesii (A. longa) -- Aristolochia indica -- Aristolochia rotunda -- Artemisia absinthium -- Artemisia vulgaris -- Asparagus adscendens -- Asparagus officinalis -- Asparagus racemosus -- Atropa belladonna -- Azadirachta indica -- Bacopa monnieri -- Bauhinia tomentosa -- Berberis Aristata -- Berberis vulgaris -- Bombyx mori -- Borago officinalis -- Boswellia serrata -- Brassica nigra -- Butea monosperma -- Caccinia macranthera var. glauca (C. glauca) -- Caesalpinia bonduc (Caesalpinia bonducella) -- Cannabis sativa -- Capparis spinosa -- Cardiospermum halicacabum -- Carthamus tinctorius -- Carum carvi -- Cassia fistula -- Catharanthus roseus -- Celastrus paniculatus -- Centaurea behen -- Centella asiatica -- Chamaecrista absus (Cassia absus) -- Chamaemelum nobile (Anthemis nobilis) -- Cheilocostus speciosus (Costus Speciosus) -- Cichorium intybus -- Cinnamomum camphora -- Cinnamomum cassia -- Cinnamomum verum (C. zeylanicum) -- Citrullus colocynthis -- Clitoria ternatea -- Colchicum autumnale -- Colchicum luteum -- Commiphora gileadensis (C. opobalsamum) -- Commiphora myrrha -- Commiphora wightii (C. mukul) -- Convolvulus scammonia -- Cotoneaster nummularius -- Crocus sativus -- Croton tiglium -- Cullen corylifolium (Psoralea corylifolia) -- Cuminum cyminum -- Curcuma aromatica -- Curcuma longa -- Curcuma zedoaria -- Cuscuta chinensis -- Cuscuta reflexa -- Cydonia oblonga -- Cymbopogon schoenanthus -- Cyperus rotundus -- Datura stramonium -- Delphinium denudatum -- Dolichousnea longissimi (Usnea longissima) -- Doronicum pardalianches -- Embelia ribes -- Euphorbia hirta -- Euphorbia resinifera -- Ferula assa-foetida -- Ficus carica -- Ficus racemosa -- Foeniculum vulgare -- Fumaria officinalis -- Gentiana lutea -- Glycyrrhiza glabra -- Gymnema sylvestre -- Helleborus niger -- Hemidesmus Indicus -- Hibiscus rosa-sinensis -- Holarrhena pubescens (Holarrhena antidysenterica) -- Hyoscyamus niger -- Hyssopus officinalis -- Illicium verum -- Iris germanica -- Juniperus communi -- Justicia adhatoda (Adhatoda vasica) -- Lactuca sativa -- Lavandula stoechas -- Lawsonia inermis -- Lepidium sativum -- Linum usitatissimum -- Lupinus albus -- Malva sylvestris -- Marrubium vulgare -- Matricaria chamomilla -- Melia azedarach -- Melilotus officinalis -- Melissa officinalis -- Mesua ferrea -- Momordica charantia -- Moringa oleifera -- Myristica fragrans -- Myrtus communis -- Nageia nagi -- Nepeta cataria -- Nigella sativa -- Ocimum basilicum -- Ocimum gratissimum -- Ocimum tenuiflorum (Ocimum sanctum -- Operculina turpethum -- Paeonia emodi -- Pandanus odorifer (Pandanus Odoratissimus) -- Papaver somniferum -- Persicaria bistorta -- Phyllanthus emblica (Emblica officinalis) -- Picrorhiza kurroa -- Pimpinella anisum -- Piper cubeba -- Piper nigrum -- Pistacia lentiscus -- Plantago major -- Plantago ovata -- Plumbago zeylanica -- Polygonum aviculare -- Portulaca oleracea -- Quercus infectoria -- Rauvolfia serpentina -- Rheum emodi -- Rheum officinale -- Ricinus communis -- Rubia cordifolia -- Rumex vesicarius -- Ruta graveolens -- Salix caprea -- Salvia officinalis -- Santalum album -- Saussurea lappa -- Semecarpus anacardium -- Senna alexandrina -- Senna occidentalis -- Senna tora -- Sida cordifolia -- Smilax china;- Solanum americanum (S. nigrum) -- Sterculia urens -- Strychnos nux-vomica -- Swertia chirata -- Symplocos racemosa -- Syzygium cumini (Eugenia jambolana) -- Tamarindus indica -- Taraxacum officinale -- Taxus baccata -- Tephrosia purpurea -- Terminalia bellirica -- Terminalia chebula -- Thymus vulgaris -- Tinospora cordifolia -- Trachyspermum ammi (Ptychotis coptica) -- Tribulus terrestris -- Trigonella foenum-graecum -- Tussilago farfara -- Valeriana jatamansi (Nardostachys jatamansi) -- Verbena officinalis -- Vernonia anthelmintica (Baccharoides anthelmintica) -- Vigna unguiculata (Dolichos biflorus) -- Viola odorata -- Viscum album -- Withania somnifera -- Wrightia tinctoria -- Zingiber officinale -- Zingiber zerumbet -- Ziziphus jujuba -- Abbreviations -- Glossary -- Ayurvedic Terms of Diseases -- List of Referenced Books -- Index.
    Abstract: This book is designed to provide pharmacologists and researchers of natural products a comprehensive review of 200 medicinal plants, their vernacular names in various languages and their medicinal uses around the world, and in some cases, a historical perspective. Chemical constituents of each plant with the putative active constituent, and available up to date pharmacological studies (until 2017 on PubMed) with each medical activity explored and its relationship with traditional uses, are described for each plant. Any variations in chemical constituents and their effects on pharmacological studies outcome have been highlighted. All clinical trials conducted, with sufficient details, have been included. Nationalities and racial identities of participants of clinical trials are identified to impress upon the social, cultural and dietary influences on the clinical outcomes. Toxicity studies and potential interactions with prescribed drugs, and full spectrum of references are included.
    Type of Medium: Online Resource
    Pages: XXX, 2156 p. 199 illus., 198 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030168070
    URL: https://doi.org/10.1007/978-3-030-16807-0
    DOI: 10.1007/978-3-030-16807-0
    DDC: 615
    Language: English
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  • 8
    Online Resource
    Online Resource
    Therapeutic Applications of Dopamine D3 Receptor Function : New Insight After 30 Years Of Research (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Neurosciences. ; Psychiatry. ; Pharmacology. ; Neuroscience. ; Psychiatry.
    Description / Table of Contents: Preface -- A Historic Review of the D3 Dopamine System from D3 Cloning to Clinical Trials in Schizophrenia and Drug Addiction -- Location, Location, Location: The Expression of D3 Dopamine Receptors in the Nervous System -- Recent Advances in Dopamine D3 Receptor Heterodimers: Focus on Dopamine D3 and D1 Receptor-Receptor Interaction and Striatal Function -- Involvement of DA D3 Receptor and Mitochondrial Functions in Structural Neuroplasticity of the Emotional Brain Circuits: Possible Role in Depression -- Dopamine D3 Receptor in Parkinson Disease: A Prognosis Biomarker and an Intervention Target -- Dopamine D3 Receptors: A Potential Target to Treat Motivational Deficits in Parkinson’s Disease -- Therapeutic Challenges of Cognitive Dysfunctions in Neuropsychiatric Disorders: Focus on the Dopamine D3 Receptor -- Dopamine D3 Receptor in Stimulant and Opiate Use Disorders -- The Role of D3 Dopamine-Receptors in Nicotine Dependence: A Synthesis of the Pre-Clinical and Clinical Literature -- The Dopamine D3 receptor in Food Addiction -- The Dopamine D3 Receptor Pharmacology and the Therapeutic Use of D3 Receptor Ligands in Schizophrenia -- D3 receptors and Restless Legs Syndrome -- D3 receptors and PET imaging.
    Abstract: The CTBN volume Therapeutic Applications of Dopamine D3 Receptor Function reviews the state of the knowledge on the dopamine D3 receptor and its role in human behavior and disease (i.e.: neuropsychiatric illnesses including schizophrenia, mood disorders, Parkinson’s disease, restless legs syndrome, addictions and substance use disorders). The volume is written by leading experts across multidisciplinary areas (imaging, biobehavioral testing and clinical trials, preclinical models / molecular pharmacology) converging on the therapeutic implications / potential of the D3 receptor. The D3 dopamine receptor is a member of the D2-like family of G protein-coupled receptors. It was cloned and characterized almost 25 years ago. A key feature of the D3 dopamine receptor system, which has attracted considerable attention, is its anatomical localization remarkably restricted to the limbic circuitry. This has spurred the hypothesis that D3 involvement could contribute to the pathophysiology of neuropsychiatric disorders (or to some features of neuropsychiatric disorders), including but not limited to psychosis, addictions and substance abuse, mood and movement disorders.
    Type of Medium: Online Resource
    Pages: VIII, 275 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031230585
    Series Statement: Current Topics in Behavioral Neurosciences, 60
    URL: https://doi.org/10.1007/978-3-031-23058-5
    DOI: 10.1007/978-3-031-23058-5
    DDC: 615
    Language: English
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  • 9
    Online Resource
    Online Resource
    Approaching Complex Diseases : Network-Based Pharmacology and Systems Approach in Bio-Medicine (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Bioinformatics. ; Oncology. ; Medicine Philosophy. ; Pharmacology. ; Computational and Systems Biology. ; Oncology. ; Philosophy of Medicine.
    Description / Table of Contents: Chapter 1. Revisiting the concept of human disease (Mariano Bizzarri, Mirko Minini, and Noemi Monti) -- Chapter 2. Dynamical aspects of pharmacokinetic/pharmacodynamics and quantitative systems pharmacology models (Ioannis Loisios-Konstantinidis, Panteleimon D. Mavroudis, Panos Macheras) -- Chapter 3. The efficiency of multi-target drugs: a network approach (Lucas N. Alberca, Alan Talevi) -- Chapter 4. Mining Complex Biomedical Literature for Actionable Knowledge on Rare Diseases (Vinicius M. Alvesa, Stephen J. Capuzzia, Nancy Baker, Eugene N. Muratov, Alexander Trospsha, and Anthony J. Hickey) -- Chapter 5. Big Data, Personalized Medicine and Network Pharmacology: beyond the current paradigms (Alessandro Giuliani and Virginia Todde) -- Chapter 6. Epigenetic Control Using Small Molecules in Cancer (Tomohiro Kozako, Yukihiro Itoh, Shinichiro Honda, Takayoshi Suzuki) -- Chapter 7. Multiscale Modelling of Cancer: Micro-, Meso- and Macro-scales of Growth and Spread (Mark AJ Chaplain) -- Chapter 8. Precision Oncology vs Phenotypic approaches in the management of cancer: a case for the postmitotic state (Armando Aranda-Anzaldo and Myrna A.R. Dent) -- Chapter 9. Migrastatics - anti-metastatic drugs targeting cancer cell invasion (Aneta Gandalovičová , Daniel Rosel , Jan Brábek) -- Chapter 10. Critical steps in Epithelial-Mesenchymal transition as target for cancer treatment (Evgeny V. Denisov, Mohit Kumar Jolly, Vitaly P. Shubin, Alexey S. Tsukanov, Nadezhda V. Cherdyntseva) -- Chapter 11. Targeting the tumor-associated macrophages for ‘normalizing’ cancer (Julia Kzhyshkowska) -- Chapter 12. Tumor Reversion induced by embryo and oocyte extracts (Sara Proietti, Andrea Pensotti and Alessandra Cucina) -- Chapter 13. Trabectedin, a drug acting on both cancer cells and the tumor microenvironment (Paola Allavena, Manuela Liguori, Cristina Belgiovine) -- Chapter 14. Advances in Characterizing Recently-identified Molecular Actions of Melatonin: Clinical Implications (Russel J. Reiter, Ramaswamy Sharma, Sergio A. Rosales-Corral, Ana Coto-Montes, Jose Antonio Boga, Jerry Vriend) -- Chapter 15. Multitarget activities of Inositol and Inositol Hexakisphosphate (Ivana Vucenik) -- Chapter 16. Integration of Phytochemicals and Phytotherapy into Cancer Precision Medicine (Nadire Özenver and Thomas Efferth) -- Chapter 17. Synergistic Effects of Chinese Herbal Medicine and Biological Networks (Deep Jyoti Bhuyan, Saumya Perera1, Kirandeep Kaur, Muhammad A. Alsherbiny, Mitchell Low, Sai-Wang Seto, Chun-Guang Li, Xian Zhou) -- Chapter 18. Medicinal herbs: its therapeutic use in obstetrics and gynaecology (Irene Orbe, Daniel Paz, Leyre Pejenaute, Andrea Puente, Laura Diaz de Alda, Sandra Yague, Iñaki Lete) -- Chapter 19. Overcoming Antibiotic Resistance: New Perspectives (Matteo Bassetti, Elda Righi).
    Abstract: This volume – for pharmacologists, systems biologists, philosophers and historians of medicine – points to investigate new avenues in pharmacology research, by providing a full assessment of the premises underlying a radical shift in the pharmacology paradigm. The pharmaceutical industry is currently facing unparalleled challenges in developing innovative drugs. While drug-developing scientists in the 1990s mostly welcomed the transformation into a target-based approach, two decades of experience shows that this model is failing to boost both drug discovery and efficiency. Selected targets were often not druggable and with poor disease linkage, leading to either high toxicity or poor efficacy. Therefore, a profound rethinking of the current paradigm is needed. Advances in systems biology are revealing a phenotypic robustness and a network structure that strongly suggest that exquisitely selective compounds, compared with multitarget drugs, may exhibit lower than desired clinical efficacy. This appreciation of the role of polypharmacology has significant implications for tackling the two major sources of attrition in drug development, efficacy and toxicity. Integrating network biology and polypharmacology holds the promise of expanding the current opportunity space for druggable targets.
    Type of Medium: Online Resource
    Pages: XVI, 483 p. 49 illus., 41 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030328573
    Series Statement: Human Perspectives in Health Sciences and Technology, 2
    URL: https://doi.org/10.1007/978-3-030-32857-3
    DOI: 10.1007/978-3-030-32857-3
    DDC: 615
    Language: English
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  • 10
    Online Resource
    Online Resource
    Pharmacology of Potassium Channels (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Human physiology. ; Neurosciences. ; Pharmacology. ; Human Physiology. ; Neuroscience.
    Description / Table of Contents: Comparison of K+ Channel families -- High-resolution structures of K+ channels -- Pharmacological approaches to studying potassium channels -- Cardiac K+ channels and channelopathies -- Cardiac hERG K+ channel as safety and pharmacological target -- Pharmacology of A-type K+ channels -- Kv7 channels and hyperexcitability disorders -- Pharmacological activation of neuronal voltage-gated Kv7/KCNQ/M-channels for potential therapy of epilepsy and pain -- Potassium channels in cancer -- Kir channel molecular physiology, pharmacology and therapeutic implications -- The pharmacology of ATP-sensitive K+ channels (KATP) -- Calcium-activated K+ channels (KCa) and therapeutic implications -- The Pharmacology of two-pore domain potassium channels -- Control of biophysical and pharmacological properties of potassium channels by ancillary subunits -- Peptide toxins targeting KV channels -- Therapeutic antibodies targeting potassium ion channels.
    Abstract: The aim of the present book is to comprehensively review current advances in understanding of genetics, structural biology, pharmacology of potassium channels and their roles in disease as well as to identify current gaps in knowledge. The ultimate goal is to provide a scientific foundation for better understanding of modulatory mechanisms and pharmacology of potassium channels and to use this understanding to drive future drug discovery. This book will be a must-have for academic and industrial scientists interested in physiology, pharmacology, pathology and structure-functional relationships of ion channels. The book will also be helpful for lecturers and students in the college and university classrooms, as well as for anyone interested in the state-of-the art in modern cell biology, physiology and pharmacology. .
    Type of Medium: Online Resource
    Pages: VIII, 545 p. 70 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030840525
    Series Statement: Handbook of Experimental Pharmacology, 267
    URL: https://doi.org/10.1007/978-3-030-84052-5
    DOI: 10.1007/978-3-030-84052-5
    DDC: 615
    Language: English
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  • 11
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    Online Resource
    Nutritional Toxicology (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Nutrition   . ; Food science. ; Pharmacology. ; Nutrition. ; Food Science.
    Description / Table of Contents: 1 Preface -- 2 Effects of Nutrients/nutrition on Toxicants/toxicity -- 3 Effects of Xenobiotics on Nutrition -- 4 Effects of Antinutritional Factors on the Digestibility, Bioavailability and Quality of Protein -- 5 Natural Toxicants Originating from Food/Diet -- 6 Food contaminants -- 7 Food additives -- 8 Food contact materials -- 9 Genetically modified food -- 10 Tolerable upper limits of nutrients -- 11 Risk assessment and Risk-benefit assessment -- 12 Nutrients/Nutrition and Drug Interaction -- 13 Phytochemicals and Health -- 14 Adverse Effects of Phytochemicals.
    Abstract: This book provides a broad overview of the chemicals in food that have the potential to induce adverse health effects. Nutritional Toxicology is an interaction of nutrition, toxicology, biochemistry and food science, etc. Its main research scope involves the effects of nutrients on metabolisms of toxicants and their mechanisms, the interaction of the toxicants and contaminants originated from diet with nutrients and nutrition process, the adverse health outcome of nutrients excess, as well as methodology of research and related food and nutrition regulation process. Also the risk assessment of toxicants and contaminants in foods, and risk benefit assessment of nutrients (dietary supplementation) has become an emerging topic. This book provides novel and provocative insights into the fields of nutrition, food science and toxicology. It also offers a state-of-the-art report on recent discoveries concerning nutritional toxicology and where the field is going. It mainly focuses on advances made over the past 20 years. It will benefit graduate students, researchers and food and nutrition related regulation parties.
    Type of Medium: Online Resource
    Pages: X, 384 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811908729
    URL: https://doi.org/10.1007/978-981-19-0872-9
    DOI: 10.1007/978-981-19-0872-9
    DDC: 615
    Language: English
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  • 12
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    Online Resource
    Network Pharmacology (2021)
    Singapore :Springer Nature Singapore :
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    Keywords: Pharmacology. ; Pharmacy. ; Bioinformatics. ; Pharmacology. ; Pharmacy. ; Bioinformatics.
    Description / Table of Contents: Chapter 1. 'Network Target' Theory and Network Pharmacology -- Chapter 2. Application of Network Pharmacology Based on Artificial Intelligence Algorithm in Drug R & D -- Chapter 3. Commonly used Network Pharmacology Database -- Chapter 4. Commonly used Network Pharmacology Software -- Chapter 5. Network Pharmacology and TCM Modernization Case Studies -- Chapter 6. Network Pharmacology and Modern Drug R & D Cases -- Chapter 7. Drug-based Network Pharmacology Practice Process -- Chapter 8. Disease-based Network Pharmacology Practice Process -- Chapter 9. Drug-disease-based Network Pharmacology Practice Process.
    Abstract: This book introduces “network pharmacology” as an emerging frontier subject of systematic drug research in the era of artificial intelligence and big data. Network Pharmacology is an original subject of fusion system biology, bioinformatics, network science and other related disciplines. It emphasizes on starting from the overall perspective of the system level and biological networks, the analysis of the laws of molecular association between drugs and their treatment objects, reveals the systematic pharmacological mechanisms of drugs, and guides the research and development of new drugs and clinical diagnosis and treatment. After it was proposed, network pharmacology has been paid attention by researchers, and it has been rapidly developed and widely used. In order to systematically reveal the biological basis of diagnosis and treatment in traditional Chinese medicine and modern medicine, we proposed a new concept of "network target" for the first time, which has become the core theory of "network pharmacology". The core principle of a network target is to construct a biological network that can be used to decipher complex diseases. The network is then used as the therapeutic target, to which multicomponent remedies are applied. This book mainly includes four parts: 1) The concept and theory of network pharmacology; 2) Common analysis methods, databases and software in network pharmacological research; 3) Typical cases of traditional Chinese medicine modernization and modern drug research based on network pharmacology; 4) Network pharmacology practice process based on drugs and diseases.
    Type of Medium: Online Resource
    Pages: XVII, 468 p. 163 illus., 119 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811607530
    URL: https://doi.org/10.1007/978-981-16-0753-0
    DOI: 10.1007/978-981-16-0753-0
    DDC: 615
    Language: English
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  • 13
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    Online Resource
    Environment and Female Reproductive Health (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Midwifery. ; Public health. ; Pharmacology. ; Midwifery. ; Public Health.
    Description / Table of Contents: Part I Environmental Harmful Factors -- 1 Introduction to Environmental Harmful Factors -- Part II Female Reproductive Processes and Diseases -- 2 Introduction of Female Reproductive Processes and Reproductive Diseases -- Part III Effects of Environmental Factors on Reproductive Process -- 3 The Influence of Environmental Factors on Ovarian Function, Follicular Genesis, and Oocyte Quality -- 4 Effects of environment and lifestyle factors on premature ovarian failure -- 5 Effects of Environment and Lifestyle Factors on Anovulatory Disorder -- 6 Effects of Cigarette Smoking on Preimplantation Embryo Development -- 7 Toxicical effects of BPDE on dysfunctions of female trophoblast cells -- 8 The Roles of Stress-Induced Immune Response in Female Reproduction -- 9 Effects of Environmental EDCs on Oocyte Quality, Embryo Development and the Outcome in Human IVF Process -- Part IV Effects of Environmental Factors on Reproductive Diseases -- 10 Effects of environmental endocrine-disrupting chemicals on female reproductive health -- 11 Definition and Multiple Factors of Recurrent Spontaneous Abortion -- 12 The Variations of Metabolic Detoxification Enzymes Lead to Recurrent Miscarriage and their Diagnosis Strategy -- Part V Effects of Environmental Factors on Fertility Preservation -- 13 The Effects of Negative Elements in Environment and Cancer on Female Reproductive System.
    Abstract: This book will focus on the harmful effect of environmental toxins on female reproductive health. Reproduction is the basis of the continuation of human beings, and environment is the basis of human survival. However, environmental pollution has become a potential risk factor for human reproductive health, which not only leads to many chronic diseases, but also causes certain harm to reproductive health. Compared to male reproduction, female reproductive process is more complex, the reproductive system is more fragile, and is more vulnerable to be damaged. The aim of this book is to review the research progress, to address the challenges, and to stimulate the development in the direction of environment and female reproductive health.
    Type of Medium: Online Resource
    Pages: XI, 313 p. 13 illus., 10 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789813341876
    Series Statement: Advances in Experimental Medicine and Biology, 1300
    URL: https://doi.org/10.1007/978-981-33-4187-6
    DOI: 10.1007/978-981-33-4187-6
    DDC: 615
    Language: English
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  • 14
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    Online Resource
    Organic Cation Transporters in the Central Nervous System (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Human physiology. ; Molecular biology. ; Pharmacology. ; Human Physiology. ; Molecular Biology.
    Description / Table of Contents: General Overview of Organic Cation Transporters in Brain -- Organic Cation Transporter Expression and Function in the CNS -- Genetic and Epigenetic Regulation of Organic Cation Transporters -- Experimental Methods for Investigating Uptake 2 Processes In Vivo -- Substrates and inhibitors of OCTs and PMAT and therapeutic implications -- Organic Cation Transporters in Brain Histamine Clearance: Physiological and Psychiatric Implications -- Organic Cation Transporters in Brain Catecholamine Homeostasis -- The Interaction of Organic Cation Transporters 1-3 and PMAT with Psychoactive Substances -- Organic Cation Transporters in Psychiatric Disorders -- Organic Cation Transporters and Nongenomic Glucocorticoid Action -- Brain Plasma Membrane Monoamine Transporter in Health and Disease -- Regulation of Neurogenesis by Organic Cation Transporters: Potential Therapeutic Implications -- Organic Cation Transporter (OCT/OCTN) Expression at Brain Barrier Sites: Focus on CNS Drug Delivery.
    Abstract: Rapidly growing interest in the role of organic cation transporters (OCTs) and plasma membrane monoamine transporter (PMAT) in central monoamine homeostasis makes this book especially timely, given its thematic alignment with the role of OCTs and PMAT in CNS. This book discusses latest insights into the field laying an emphasis on health, disease and therapeutics. The chapter, “General Overview of Organic Cation Transporters in Brain”, of this book is available open access under a CC BY 4.0 license at link.springer.com.
    Type of Medium: Online Resource
    Pages: XII, 328 p. 70 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030829841
    Series Statement: Handbook of Experimental Pharmacology, 266
    URL: https://doi.org/10.1007/978-3-030-82984-1
    DOI: 10.1007/978-3-030-82984-1
    DDC: 615
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  • 15
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    Online Resource
    The Carbonic Anhydrases: Current and Emerging Therapeutic Targets (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Clinical biochemistry. ; Pharmacy. ; Pharmacology. ; Medical Biochemistry. ; Pharmacy.
    Description / Table of Contents: Dedication -- Preface.-The carbonic anhydrases in health and disease -- Carbonic anhydrase isozymes as diagnostic biomarkers and therapeutic targets -- Targeting carbonic anhydrases in vascular and pulmonary disease -- Carbonic anhydrase inhibitors in ophthalmology: glaucoma and macular oedema -- Targeting carbonic anhydrase isozymes in the treatment of neurological disorders -- Potential of carbonic anhydrase inhibitors in the treatment of oxidative stress and diabetes -- An overview of carbonic anhydrase-related neoplasms -- The carbonic anhydrase IX interactome and the regulation of cancer progression -- Carbonic anhydrase IX: current and emerging therapies -- Carbonic anhydrase inhibitors: designing isozyme-specific inhibitors as therapeutic agents -- Carbonic anhydrase inhibitors: identifying therapeutic cancer agents through virtual screening -- Targeting carbonic anhydrase IX in tumour imaging and theranostic cancer therapy.
    Abstract: This volume assembles and integrates the wealth of diverse information that is now accumulating in this burgeoning field. The existing and potential therapeutic applications of targeting CA cover a remarkably wide-range of diseases and disorders and have generated increasing and extensive interest in recent years. Its inter-disciplinary approach embraces both the most up-to-date therapeutic application of CA-targeting and the latest research data that will provide a platform for the development of novel applications. The interested audience comprises scientists and clinicians from many relevant disciplines within science and medicine.
    Type of Medium: Online Resource
    Pages: XII, 288 p. 38 illus., 22 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030795115
    Series Statement: Progress in Drug Research, 75
    URL: https://doi.org/10.1007/978-3-030-79511-5
    DOI: 10.1007/978-3-030-79511-5
    DDC: 615
    Language: English
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  • 16
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    Online Resource
    Pharmacology of the WNT Signaling System (2021)
    Cham :Springer International Publishing :
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    Keywords: Pharmacology. ; Physiology. ; Oncology. ; Neurosciences. ; Developmental biology. ; Pharmacology. ; Physiology. ; Oncology. ; Neuroscience. ; Developmental Biology and Stem Cells.
    Description / Table of Contents: Pharmacological thinking in WNT signaling -- Controlling WNT Signaling Specificity and implications for targeting WNTs pharmacologically -- WNTs on exosomes -- Strategies to target LRPs in WNT signaling -- Targeting the receptor tyrosine kinase ROR1 by small molecules -- Assessing WNT binding and Frizzled activation employing genetically encoded, biophysical sensors -- Disheveled proteins as crucial mediators of WNT signaling -- Destruction complex and regulation of CTNNB1 -- Strategies to therapeutically target WNT/PCP like signaling in disease -- Mining natural compounds to target WNT signaling - from mushrooms to corals -- FZD7 as a therapeutic target in intestinal cancer -- Targeting oncogenic WNT signaling with WNT derived peptides -- Targeting WNT signaling in lung pathology -- The role of WNT signaling in osteoarthritis and the therapeutic potential of its pharmacological targeting -- WNT signaling in Alzheimers disease and other neurodegenerative disorders - opportunities for therapy? -- Targeting WNT signaling as a risk.
    Abstract: This book reflects the state of the art of our understanding of the WNT signaling system, which comprises a network of signaling pathways initiated by the secreted WNT lipoglycoproteins, which are crucial for embryonal development, stem cell regulation, tissue homeostasis and repair. Dysfunction of this evolutionarily conserved signaling system leads to many diseases including developmental disorders, diverse forms of cancer, fibrosis, neurodegenerative disease and many more. The WNT signaling system is built upon 19 mammalian, secreted WNT lipoglycoproteins that interact with a plethora of distinct receptors, such as the G protein-coupled receptors called Frizzleds (FZD1-10), LDL receptor-like proteins (LRP5/6), receptor tyrosine kinases (ROR1, 2, RYK and PTK7). In addition, WNT pathways are tightly regulated by many secreted and cell-intrinsic negative regulators, such as soluble FZD-related proteins (SFRPs), Dickkopfs (DKKs), WNT-inhibitory proteins, TIKI, RNF43 and more. Understanding the basic mechanism in terms of receptor-ligand interaction, receptor selectivity, signal initiation and desensitization remain poorly understood, even though substantial advances have been made the recent years. Due to the involvement of the WNT signaling system in human disease, it appears obvious to target diverse branches pharmacologically and therapeutically. However, given the complexity of the system and its importance for stem cell regulation and tissue maintenance, therapy comes with obvious risks for severe side effects. The field is addressing the challenge to identify suitable targets and selective compounds for therapy allowing disease-selective therapeutic effects and balancing unwanted side effects. This book summarizes the current understanding of the basic and applied pharmacology in the WNT signaling system and bridges disciplines such as pharmacology, physiology, neurosciences, oncology and drug development.
    Type of Medium: Online Resource
    Pages: VIII, 422 p. 70 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030854997
    Series Statement: Handbook of Experimental Pharmacology, 269
    URL: https://doi.org/10.1007/978-3-030-85499-7
    DOI: 10.1007/978-3-030-85499-7
    DDC: 615
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  • 17
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    Online Resource
    The Art of Carbohydrate Analysis (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Chemistry, Organic. ; Food science. ; Biotechnology. ; Pharmacology. ; Organic Chemistry. ; Food Science. ; Biotechnology.
    Description / Table of Contents: Chapter 1 The World of Carbohydrates -- Chapter 2 Basic Knowledge of Glycobiology -- Chapter 3 Carbohydrates involved in Diseases -- Chapter 4 Detection of Carbohydrate by Colorimetric Methods -- Chapter 5. Analytical Techniques to Study Carbohydrates -- Chapter 6 Monosaccharide Composition Analysis -- Chapter 7 Carbohydrate Analysis of Glycoconjugates -- Chapter 8 Structural Characterization of Released Glycans -- Chapter 9 Analysis of Sialic Acids -- Chapter 10 Carbohydrate Microarray Technology -- Chapter 11 Analysis of Carbohydrates by Mass Spectrometry -- Chapter 12 Analysis of Carbohydrates by Nuclear Magnetic -- Chapter 13 Glycobioinformatics -- Chapter 14 Concluding Remarks. .
    Abstract: The growing importance of glycobiology and carbohydrate chemistry in modern biotechnology and the pharmaceutical industry makes accurate carbohydrate analysis indispensable. This book provides the principles and protocols of various fundamental carbohydrate analysis methods. Choice of method is entirely dependent upon the type of material being investigated (biological samples, food products, etc.), and the level of structural detail required, i.e. sugar content, compositional analysis, linkages between the sugar components, or the total chemical structure of a given molecule. Full structural characterization of carbohydrate chains requires significant time, resources, and skill in several methods of analysis; no single technique can address all glycan analysis needs. This book summarizes several existing analytical techniques (both chemical and physical) in an introductory volume designed for the non-expert researcher or novice scientist. While background in carbohydrate chemistry is assumed, all information necessary to understanding the described techniques is addressed in the text.
    Type of Medium: Online Resource
    Pages: XXV, 350 p. 117 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030777913
    Series Statement: Techniques in Life Science and Biomedicine for the Non-Expert,
    URL: https://doi.org/10.1007/978-3-030-77791-3
    DOI: 10.1007/978-3-030-77791-3
    DDC: 615
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  • 18
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    Online Resource
    Polypharmacology : Principles and Methodologies (2022)
    Cham :Springer International Publishing :
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    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Drug delivery systems. ; Neuropharmacology. ; Pharmacology. ; Pharmaceutics. ; Drug Delivery. ; Neuropharmacology.
    Description / Table of Contents: PART I. Polypharmacology as a New Branch of Pharmacology: Concept and Principles -- Basics of Polypharmacology -- Polypharmacology in Clinical Applications: Multitarget Multidrug-combination (MTMD-C) -- Polypharmacology in Clinical Applications: Multitarget Multidrug-single-formulation (MTMD-SF) -- Polypharmacology in Clinical Applications: Multitarget Single-drug (MTSD) -- Polypharmacology in Drug Discovery: Designed Epigenetic MTSD and Small-molecule MTSD -- Anti-cancer Polypharmacology -- Cardiovascular Polypharmacology -- Neuronal Polypharmacology -- Pulmonary Polypharmacology -- Polypharmacology of Metabolic Disease -- Polypharmacology of Infectious Disease -- Polypharmacology of Inflammation -- Anti-psychotics Polypharmacology -- Anti-aging Polypharmacology -- Polypharmacology in Drug Repurposing -- Polypharmacology and Unintended Drug Promiscuity -- Polypharmacology Pharmacokinetics -- The Future of Polypharmacology -- PART II. Polypharmacology in New Drug Development: Strategies and Protocols -- Designed MTSD Discovery Process -- Designed MTSD Discovery Strategies -- Designed MTSD Discovery Technologies -- Designed MTSD Discovery Databases -- Designed MTSD Target Deconvolution.-Designed MTSD Target Validation -- Designed MTSD Lead Identification and Optimization -- Designed MTSD Discovery Protocols -- Natural Products in MTSD Discovery -- Polypharmacology Procedures for Drug Repurposing -- Polypharmacology Procedures for Drug Promiscuity Discovery.
    Abstract: There is a growing interest in unmet needs for the development of a new discipline in drug discovery and in university education on Polypharmacology. However, there has not been a book with the comprehensive compilation of basic knowledge and advanced methodology on Polypharmacology. This book aims to meet the needs of making Polypharmacology a new sub-discipline of Pharmacology, not only being a hot area of pharmacological research and education but also a new paradigm for drug discovery. It contains the contents covering the entire scope of Polypharmacology including systemic in-depth exposition of basic knowledge, novel concepts, innovative technologies, and translational and clinical applications by showcasing state-of-the-art strategies and step-by-step instructions of cutting-edge methods. The contents of Polypharmacology targets broad readerships including scientists in pharmacology research and drug development, and university teachers and graduates in medical school or school of pharmacy. Rich in illustrations and tables to showcase readers for better understanding the concepts and technologies related to Polypharmacology; Provides comprehensive, systemic, holistic, and explicit explanations and discussion of the fundamental knowledge, background information, conceptual evolution, and updated methodology, as well as in-depth mechanisms behind the knowledge and methodology of Polypharmacology; Main emphasis on rationally designed Polypharmacology or “multi-target, single-drug (MTD)” pharmacology, which represents the major future direction of Polypharmacology and Pharmacology; Describes the clinical applications of Polypharmacology to various human diseases in the clinical and preclinical settings; Contains a wide collection of the state-of-the-art Polypharmacology technologies applicable to the designed MTD discovery and the step-by-step descriptions of drug discovery process applying Polypharmacology principles and methodologies.
    Type of Medium: Online Resource
    Pages: XXV, 856 p. 12 illus., 9 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031049989
    URL: https://doi.org/10.1007/978-3-031-04998-9
    DOI: 10.1007/978-3-031-04998-9
    DDC: 615
    Language: English
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  • 19
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    Online Resource
    Advanced Drug Delivery Strategies for Targeting Chronic Inflammatory Lung Diseases (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Nanobiotechnology. ; Biomedical engineering. ; Drug delivery systems. ; Pharmaceutical chemistry. ; Pharmacology. ; Nanobiotechnology. ; Biomedical Engineering and Bioengineering. ; Drug Delivery. ; Pharmaceutics.
    Description / Table of Contents: Chapter 1. An introduction to respiratory diseases and an emerging need for efficient drug delivery systems -- Chapter 2. Inflammatory respiratory diseases: Correlation between Lung cancer and CoVid-19 -- Chapter 3. Advancements in translational respiratory research using nanotechnology -- Chapter 4. Chemical moieties as advanced therapeutics for targeting respiratory disorders -- Chapter 5. Phytochemicals and their nanoformulations targeted for pulmonary diseases -- Chapter 6. Nanocarriers: an advanced and highly effective approach for targeting chronic lung diseases -- Chapter 7. Vesicular drug delivery systems in respiratory diseases -- Chapter 8. Nanoparticles in chronic respiratory diseases -- Chapter 9. Applications of nanotechnology in pulmonary disease diagnosis -- Chapter 10. Nanotechnology in pulmonary disease diagnosis -- Chapter 11. Recent trends in Nanomedicine for diagnosis and treatment of pulmonary diseases -- Chapter 12. Strategies for enhanced drug targeting to inflamed lungs: Novel perspectives -- Chapter 13. Solid-Lipid Nanocarriers (SLN’s) based drug delivery for treating various pulmonary diseases -- Chapter 14. Microparticles, microspheres and microemulsions as pulmonary drug delivery systems for the treatment of respiratory diseases -- Chapter 15. Microparticles, microspheres and microemulsions in respiratory diseases -- Chapter 16. Advanced drug delivery systems targeting the immune system at cellular level in chronic respiratory diseases -- Chapter 17. Targeted Micellar Systems for Pulmonary Disease Intervention -- Chapter 18. Polymeric and inorganic nanoparticles targeting chronic respiratory diseases -- Chapter 19. Mucoadhesive drug delivery system in chronic respiratory diseases -- Chapter 20. Liposomal Drug Delivery: Therapeutic Applications in Chronic Respiratory Diseases -- Chapter 21. Biologics and vaccines for nasal and pulmonary drug delivery -- Chapter 22. Drug delivery systems for respiratory infections -- Chapter 23. Cell and Gene Therapies for Chronic Inflammatory Lung Diseases - Emerging Technological Trends and Advancements in Respiratory Medicine -- Chapter 24. Targeting biofilms in respiratory diseases using novel drug delivery systems -- Chapter 25. Advanced nanomaterials for drug delivery in chronic respiratory disorders -- Chapter 26. Emerging technological trends and advancements in respiratory medicine -- Chapter 27. Pulmonary pharmacokinetics and Biophysics -- Chapter 28. Clinical trials on novel advanced drugs for chronic respiratory disorders.
    Abstract: This book describes the growing clinical and healthcare relevance of nano-therapeutics in treating respiratory diseases. It begins with a brief introduction on the different types of nanoparticles in respiratory disease conditions. It further discusses the current trends in understanding the disease pathology using different in vitro and in vivo models, which are important towards the onsite clinical applications and development of new therapeutics. The book includes exciting topics such as formulation of these nanoparticles, targeting various organelles etc. It also describes the future prospects and challenges in the field. Different chapters are written by researchers actively working in the area of pulmonary diseases. This book is designed to address the requirements of both beginners and specialized scientists involved in pulmonary research. The contents include basic concepts followed by advanced state-of-art monitoring and treatment of diseases. The book is meant for researchers and industry experts in nanotechnology, pharmaceutical sciences and drug design.
    Type of Medium: Online Resource
    Pages: X, 655 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811643927
    URL: https://doi.org/10.1007/978-981-16-4392-7
    DOI: 10.1007/978-981-16-4392-7
    DDC: 615
    Language: English
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  • 20
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    Online Resource
    Data Monitoring Committees (DMCs) : Past, Present, and Future (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Medical sciences. ; Drug development. ; Medicine Research. ; Biology Research. ; Pharmaceutical chemistry. ; Biometry. ; Toxicology. ; Pharmacology. ; Preclinical Research. ; Biomedical Research. ; Pharmaceutics. ; Biostatistics. ; Medical Toxicology.
    Description / Table of Contents: Introduction-.What is a DMC?-. Is a DMC required?-. Who is On the DMC?-. What are the Legal and Ethical Aspects of DMC?-. How does the DMC work with SDAC and Sponsor and External Groups ? -- What Does a DMC Meeting Look Like -- What data is used for DMC outputs and who programs? -- What is Included in DMC Outputs? -- What does the DMC final DMC outputs look like and how is it delivered? -- What Types of Safety Outputs Does the DMC Receive? -- What types of efficacy outputs does the DMC receive? -- What types of other outputs does the DMC receive? -- What About In-Between DMC Meetings -- What types of formal interim analyses does the DMC review? -- What does the paperwork from meetings look like? -- How does the DMC assess risk-benefit for their decision making? -- What are some examples? -- Conclusions.
    Abstract: This book provides an overview of Data Monitoring Committees - what was done in the past, what is currently being done, and thoughts on improvements for the future. Previous works focused primarily on large cardiovascular studies (where DMCs originated more than 30 years ago) but updated references are needed that discuss smaller, more flexible studies in areas such as oncology. The authors have attended ~800 DMC meetings from ~200 distinct studies across all areas of clinical studies (oncology, rheumatology, rare diseases, cardiology, immunology, etc.) This wide range of expertise will be used, as well as the expertise that comes from working with virtually every large biotech/pharma and CRO for DMC work. The reader of the book will know when DMCs are needed or helpful, how to form the DMC, how to work with external CROs and with sponsor teams and the DMC to create needed DMC outputs, how the DMC meetings are conducted, and - especially for DMC members - what are considerations within the Closed Session to review safety/efficacy outputs to assess risk/benefit to make appropriate recommendations that protect the patient safety and trial integrity. This is a practical hands-on book on how to decide if a DMC is necessary, how to form the DMC, how to smoothly create the necessary materials for the DMC and have smooth running DMC meetings. There is no specialized training in school about how DMCs work - frequently people may have been in industry for many years without ever needing to work with a DMC. This book is the helpful reference for those new to these DMCs. The DMC work is critical to be correctly implemented as the implications of it are so great. This book provides the following: Thorough instructions on the steps needed to form and implement a Data Monitoring Committee for clinical trial evaluation; Includes practical and hands-on information on DMC implementation; Discusses a wide range of clinical trial – by phase and therapeutic area.
    Type of Medium: Online Resource
    Pages: XII, 111 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031287602
    URL: https://doi.org/10.1007/978-3-031-28760-2
    DOI: 10.1007/978-3-031-28760-2
    DDC: 615
    Language: English
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  • 21
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    Macrophage Targeted Delivery Systems : Basic Concepts and Therapeutic Applications (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Cytology. ; Toxicology. ; Immunology. ; Pharmacology. ; Pharmaceutics. ; Cell Biology. ; Toxicology. ; Immunology.
    Description / Table of Contents: Part I Anatomy, Physiology and Pharmacology of Macrophages -- Introduction to Anatomy and Physiology of Macrophages from Drug Delivery Perspective -- Introduction to Pharmacology of Macrophages from Drug Delivery Perspective -- Mechanisms and Ways of Macrophage Delivery -- Macrophage Associated Disorders: Pathophysiology, Treatment Challenges and Possible Solutions -- Understanding Macrophage Associated Diseases and Applications of Nano Drug Delivery Systems -- Part II Polymeric Nanoparticles for Macrophage Targeting -- Targeting of Macrophages: Basic and therapeutic Role of Polymeric Nanoparticles -- Polymeric Nanoparticles Based Drug and Gene Delivery to Macrophages -- Surface Modification of Nanoparticles for Macrophage Targeting -- Part III Lipid Nanoparticles for Macrophage Targeting -- Liposomes as Delivery System for Macrophage Targeting -- Solid Lipid Nanoparticles Based Drug and Gene Delivery to Macrophages -- In vivo Fate of Colloidal Carriers Undergoing Macrophage Targeting -- Nanoparticle-based Theranostics for Macrophage-associated Diseases -- Part IV Targeting Macrophages for Treatment of Various Diseases -- Tumor Associated Macrophages as Therapeutic Target for Drug/immune Therapy of Cancer -- Macrophage Targeting for Therapy of Autoimmune Diseases -- Macrophage Targeting for Therapy of Cardiovascular Diseases (CVD) -- Macrophage targeting for therapy of intracellular infections -- Targeting Drugs and Nucleic Acids to Macrophages for Therapy of Inflammatory Diseases -- Macrophage Targeted Chemotherapy for Tuberculosis and other Respiratory Disease. -- Part V Specific Formulations and Clinical Trials on Macrophage Targeted Delivery -- Nano- and Microparticles Based Dry Powder Inhalers for Pulmonary Macrophage Drug Delivery -- Recent Trends in Clinical Studies on Macrophage Targeted Delivery -- Future Directions and Challenges in Macrophage Targeting. .
    Abstract: The proposed book is envisioned for the nascent and entry-level researchers who are interested to work in the field of drug delivery and its applications specifically for macrophage targeting. Macrophages have gained substantial attention as therapeutic targets for drug delivery considering their major role in health and regulation of diseases. Macrophage-targeted therapeutics have now added significant value to the lives and quality of life of patients, without undue adverse effects in multiple disease settings. We anticipate examining and integrating the role of macrophages in the instigation and advancement of various diseases. The major focus of the book is on recent advancements in various targeting strategies using delivery systems or nanocarriers followed by application of these nanocarriers for the treatment of macrophage associated disorders. Macrophage Targeted Delivery Systems is primarily targeted to Pharmaceutical Industry & Academia, Medical & Pharmaceutical Professionals, Undergraduate & Post graduate students and Research Scholars, Ph.D, post docs working in the field of medical and pharmaceutical sciences.
    Type of Medium: Online Resource
    Pages: XVIII, 556 p. 76 illus., 73 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030841645
    URL: https://doi.org/10.1007/978-3-030-84164-5
    DOI: 10.1007/978-3-030-84164-5
    DDC: 615
    Language: English
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  • 22
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    Online Resource
    Synbiotics for the Management of Cancer (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Cancer. ; Cancer Treatment. ; Pharmacology. ; Cancers. ; Cancer Therapy.
    Description / Table of Contents: Chapter 1_Introduction to Cancer -- Chapter 2_Effect of anticancer treatment approches on gut microbiota -- Chapter 3_Synbiotic: A promising approach for the treatment of cancer -- Chapter 4_Correlation between ROS and Synbiotics for effective treatment of cancer -- Chapter 5_Influence of synbiotics on inflammation and immune microenvironment for the treatment of cancer -- Chapter 6_Synbiotics in colorectal cancer -- Chapter 7_Synbiotics in cervical cancer -- Chapter 8_Synbiotics in prostate cancer -- Chapter 9_Synbiotics in gastric cancer -- Chapter 10_Synbiotics in lung cancer -- Chapter 11_Synbiotics in small cell pancretatic cancer -- Chapter 12_Synbiotics in breast cancer -- Chapter 13_Synbiotics in hepatocellular carcinoma -- Chapter 14_Synbiotics in ovarian cancer -- Chapter 15_Regulatory issues of synbiotics in cancer.
    Abstract: This book illustrates the significance of probiotics and prebiotics for the management of various types of cancers. The up-to-date chapters provide recent information about the effect of anticancer treatment approaches on gut microbiota, the correlation between ROS and synbiotics for effective cancer treatment, and the influence of synbiotics on inflammation and immune microenvironment for cancer treatment. It also describes the regulatory issues about synbiotics in the management of cancer. This book is an essential resource for scientists working in the field of cancer, pharmaceutical & clinical sciences, and cancer clinicians. This book is also very useful for undergraduate and postgraduate students of Pharmacy and Biotechnology and medical researchers, mainly working in microbiology, immunology, and cancer biology.
    Type of Medium: Online Resource
    Pages: XVII, 340 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811975509
    URL: https://doi.org/10.1007/978-981-19-7550-9
    DOI: 10.1007/978-981-19-7550-9
    DDC: 615
    Language: English
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  • 23
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    Online Resource
    Recent Advances in Pharmaceutical Innovation and Research (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Drug delivery systems. ; Nanobiotechnology. ; Pharmacology. ; Pharmaceutics. ; Drug Delivery. ; Nanobiotechnology.
    Description / Table of Contents: Part 1. Pharmaceutical Innovation and Research -- Chapter 1. Innovation in stabilization of biopharmaceuticals -- Chapter 2. Concepts in pharmacogenomics: tools and applications -- Chapter 3. Pharmacogenetics–a new approach for the selection of the right drug -- Chapter 4. Meeting the unmet challenges of pharmaceutical research using artificial intelligence -- Chapter 5. Pharmaceutical innovation and research in ayurved -- Chapter 6. Ayurveda intervention in perimenopausal syndrome -- Part 2. Drug Discovery and Development -- Chapter 7. Innovative strategies in drug discovery and pharmacoinformatics -- Chapter 8. Advances in peptide synthesis -- Chapter 9. Peptidomimetics in Medicinal Chemistry: The Art of Transforming Peptides to Drugs -- Chapter 10. Diverse Pharmacological Activities of 4-aminoquinoline and its Derivatives -- Chapter 11. Thiourea catalysts for synthesis of active pharmaceutical ingredients -- Chapter 12. The Chemistry and Pharmacology of Mandarin Orange -- Chapter 13. Recent progress in the pharmacology of phytoestrogens: emerging neuromodulators for treating anxiety and depression -- Chapter 14. Next-generation cell-based therapies to combat metastaticbrain tumor -- Chapter 15. Pharmacokinetics and Pharmacodynamics: Fundamentals and Role(s) in Drug Discovery and Development -- Chapter 16. An update on pharmacokinetic models -- Chapter 17. Pharmacodynamics: Basics and Applications in Drug Research -- Part 3. Drug Delivery and Nanotechnology -- Chapter 18. Technological innovations in pharmaceutical drug nanocrystals -- Chapter 19. Fixed Dose Combinations: Innovations and Research -- Chapter 20. Significance of Intranasal Drug Delivery Systems: Recent Trends and Clinical Investigations in Brain Disorders -- Chapter 21. Current challenges and nanotechnology-based pharmaceutical approaches for the treatment and control of visceral leishmaniasis -- Chapter 22. Polymeric Nanoparticles-based Drug Delivery Systems for Anticancer Therapy. Chapter 23. Carbon nanotubes: a review of toxicity and applicability in biomedical applications -- Chapter 24. Recent trends in topical herbal nanotherapeutics for psoriasis -- Part 4. Pharmaceutical Microbiology -- Chapter 25. Antibiotics: past, present, future, and clinical pipeline -- Chapter 26. Innovative strategies to tackle antimicrobial resistance -- Chapter 27. Molecular and mechanistic insights of yeast flocculation -- Chapter 28. Management of hepatitis virus C: current and future treatments -- Chapter 29. Tuberculosis: experimental models, innovations and challenges -- Chapter 30. Targeting outer membrane to tackle multi-drug resistant bacterial pathogens -- Chapter 31. Diphtheria-A Paradigmatic Vaccine Preventable Toxigenic Disease with Changing Epidemiology -- Chapter 32. Emerging and re-emerging infections: an overview.
    Abstract: This book covers several important aspects of pharmaceutical research and innovations. It presents important topics on drug delivery, novel microsponge, nanocrystals, polymeric nanoparticles, peptide synthesis, biopharmaceuticals, pharmacodynamics, yeast flocculation, neuromodulators, innovative drug discovery, pharmacoinformatics, aminoquinoline, thiourea crystals for API synthesis, FDCs and formulations research, ayurveda and natural products, and innovations to militate anti-microbial resistance (AMR). A chapter is devoted to the applications of Artificial Intelligence and Machine Learning in diverse sectors of the pharmaceutical industry, including drug discovery and development, drug repurposing, and improving pharmaceutical productivity. The book also reviews the role of pharmacogenomics and pharmacogenetics in drug development and precision medicine. Further, the book presents an updated summary of recent advances in the fields of nanomedicines and nano-based drug delivery systems. This book is useful to pharmaceutical sciences students, researchers, educators, and professionals in the pharmaceutical industry to understand the intricacies of new drug research and innovations.
    Type of Medium: Online Resource
    Pages: XXI, 770 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819923021
    URL: https://doi.org/10.1007/978-981-99-2302-1
    DOI: 10.1007/978-981-99-2302-1
    DDC: 615
    Language: English
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  • 24
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    Online Resource
    Block Co-polymeric Nanocarriers: Design, Concept, and Therapeutic Applications (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Nanobiotechnology. ; Drug delivery systems. ; Pharmacology. ; Nanobiotechnology. ; Drug Delivery.
    Description / Table of Contents: Ch 1 Introduction to block co-polymers -- Ch 2 Role of block co-polymers in drug delivery -- Ch 3 Role of block co-polymers in enhancement of poor solubility of drugs -- Ch 4 Synthesis and Self–assembly of block copolymers -- Ch 5 Role of block co-polymers in treatment of brain disorders -- Ch 6 Role of block co-polymers in treatment of neurodegenerative disorders -- Ch 7 Role of block co-polymers in colon cancer -- Ch 8 Role of block co-polymers in lung cancer -- Ch 9 Role of block co-polymers in IBD -- Ch 10 Role of block co-polymers in vaccine -- Ch 11 Role of block co-polymers in treatment of GIT disorders -- Ch 12 Role of block co-polymers in topical drug delivery -- Ch 13 Role of block co-polymers in targeted drug delivery -- Ch 14 Role of block co-polymers in ocular drug delivery -- Ch 15 Role of block co-polymeric micelles in drug delivery -- Ch 16 Applications of block co-polymers as Stimuli Responsive Copolymers -- Ch 17 Patented block co-polymers for various Therapeutics Applications.
    Abstract: This book focuses on current advancements in the field of block copolymers and covers design, concept, and various therapeutic applications in the drug delivery. It also reviews the use of block copolymers in drug delivery applications from the development of sustained release products to smart polymeric delivery systems such as stimuli-responsive polymeric systems, for example, thermosensitive, redox-sensitive, photo-sensitive, and enzyme-sensitive. The book further discusses the nano assemblies from amphiphilic block copolymers as nanomedicine platforms for diagnosis and therapy due to their relatively small size, high drug loading capacity, controlled drug release, in vivo stability, and prolonged blood circulation. The chapters also review the various patents and ongoing clinical trials on the applications, covering several important new concepts and findings in the field of block copolymers. The book is aimed at researchers, academicians, and industrial scientists involved in the development of drug-delivery systems based on polymers.
    Type of Medium: Online Resource
    Pages: XVII, 429 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819969173
    URL: https://doi.org/10.1007/978-981-99-6917-3
    DOI: 10.1007/978-981-99-6917-3
    DDC: 615
    Language: English
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  • 25
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    Online Resource
    Pharmacology of Immunotherapeutic Drugs (2020)
    Cham :Springer International Publishing :
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    Keywords: Pharmacology. ; Immunology. ; Pharmacology. ; Immunology.
    Description / Table of Contents: Preface Chapter 1: Overview of the Immune System and its Pharmacological Targets -- Chapter 2: Modulation of the Innate Immune System -- Chapter 3: Modulation of the Adaptive Immune System -- Chapter 4: Respiratory Disorders of the Immune System and their Pharmacological Treatment -- Chapter 5: Inflammation of the Skin and its therapeutic topics -- Chapter 6: Inflammatory Diseases of the Gastrointestinal Tract and Pharmacological Treatments -- Chapter 7: Mechanisms of Autoimmunity and Pharmacologic Treatments -- Chapter 8: Transplantation: Immunologic Principles and Pharmacologic Agents -- Chapter 9: Immunopathogenesis, Immunization, and Treatment of Infectious Diseases -- Chapter 10: Cancer Immunotherapy.
    Abstract: Medicine has entered a golden age in which therapeutic agents are becoming widely available due to advances in basic science and technology. As such, many drugs have been developed that target inflammatory processes and/or the immune system. This book is intended for health professionals examining the modulation of inflammation by immunotherapeutic drugs. The immune system fills the primordial role of host defense and resistance to infections with pathogenic microorganisms. Several hematopoietic-derived cells constituting the innate and adaptive immune systems cooperate to provide barriers for microbial colonization and/or promote pathogen destruction within the host. Conversely, many immune cells are also involved in the pathogenesis and propagation of chronic inflammatory diseases. The beginning of this book details various components of the immune system including the cell types, lymphoid tissues, soluble cytokines and surface molecules that are essential for host defense. Breakdowns in immune tolerance, or dysregulated immune responses to antigens derived from self tissues or innocuous sources, can lead to the development of autoimmunity or chronic inflammatory diseases. Pathophysiologic roles for the immune system are detailed in corresponding chapters on autoimmunity, epithelial surfaces (lungs, skin, intestine), and transplantation, with special emphasis placed on immunotherapeutic drug targets. The last section of the book focuses on treatments that stimulate our immune system to specifically target and fight infectious diseases and cancer. In each chapter, the medications used to treat various diseases/conditions in terms of their mechanism of action and other pharmacologic properties are discussed in detail. Chapters begin with a table showing drug names and classifications. The importance of basic science and clinical trials cannot be understated in the context of drug development. As such, the discovery of certain medications that had a lasting impact in medicine and pharmacy are highlighted in chapter subsections named “Bench to Bedside.” Several clinical applications of immunotherapeutic drugs are described within end-of -chapter case studies including practice questions. The Pharmacology of Immunotherapeutic Drugs is a reference for immunologists and clinicians (medical doctors, pharmacists, nurses) examining the modulation of inflammatory processes by a variety of medications targeting the cells and mediators of our immune system.
    Type of Medium: Online Resource
    Pages: XIX, 399 p. 118 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030199227
    URL: https://doi.org/10.1007/978-3-030-19922-7
    DOI: 10.1007/978-3-030-19922-7
    DDC: 615
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  • 26
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    Online Resource
    Biomedical Applications and Toxicity of Nanomaterials (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Nanobiotechnology. ; Nanomedicine. ; Pharmacology. ; Nanobiotechnology. ; Nanomedicine and Nanotoxicology.
    Description / Table of Contents: Chapter 1. Macroporous cryogel-based systems for water treatment applications and Safety: nanocomposite-based cryogels and bacteria-based bioreactors -- Chapter 2. One dimensional Semiconducting Nanomaterials: Toxicity and Clinical Applications -- Chapter 3. Prospects of Safe use of Nanomaterials in Biomedicalapplications -- Chapter 4. Hyaluronic acid-based nanotechnologies for delivery and treatment -- Chapter 5. Theranostics nanomaterials for safe cancer treatment -- Chapter 6. Cardiovascular safety assessment of new chemical entities: current perspective and emerging technologies -- Chapter 7. Toxicology of pharmaceutical products during drug development -- Chapter 8. Safety and Risk assessment of food items -- Chapter 9. Non toxic Natural products as regulators of tumour suppressor gene function -- Chapter 10. Advancements in the safety of Plant medicine: Back to nature -- Chapter 11. Chemicals and their interaction in the aquaculture system -- Chapter 12. Zebrafish as a biomedical model to define developmental origins of chemical toxicity -- Chapter 13. Green synthesis of non toxic nanoparticles -- Chapter 14. Synthesis, characterisation and safety of titanium oxide nanoparticles -- Chapter 15. Characterisation of non toxic nanomaterials for biological applications -- Chapter 16. Toxicity assessment of nanoparticle -- Chapter 17. Safety of nanoparticles: emphasis on antimicrobial properties -- Chapter 18. Quantum dots for imaging and its safety -- Chapter 19. Genotoxicity evaluation of nanosized materia -- Chapter 20. Scaffoldmaterials and toxicity -- Chapter 21 Biological Safety and Cellular interactions of nanoparticles -- Chapter 22. Role of artificial intelligence in the toxicity prediction of drugs -- Chapter 23. Chemicals and rodent models for the safety study of alzheimer’s disease -- Chapter 24. Mitochondria-targeted liposomal delivery in Parkinson's disease: safety concerns -- Chapter 25. Routes of Nano-drug Administration and Nano-based drug delivery system and toxicity -- Chapter 26. Green Synthesised silver nanoparticles phytotoxicity and applications in agriculture: An overview -- Chapter 27 status of safety concerns of microplastic detection strategies -- Chapter 28. Impact of insecticides on man and environment.
    Abstract: This book covers the recent trends on the biological applications of nanomaterials, methods for their preparation, and techniques for their characterization. Further, the book examines the fundamentals of nanotoxicity, methods to assess the toxicity of engineered nanomaterials, approaches to reduce toxicity during synthesis. It also provides an overview of the state of the art in the application of Artificial intelligence-based methodologies for evaluation of toxicity of drugs and nanoparticles. The book further discusses nanocarrier design, routes of various nanoparticle administration, nano based drug delivery systems, and the toxicity challenges associated with each drug delivery method. It presents the latest advances in the interaction of nanoparticles with the cellular environment and assess nanotoxicity of these engineered nanoparticles. The book also explores the comparative and mechanistic genotoxicity assessment of the nanomaterials. This book is useful source of information for industrial practitioners, policy makers, and other professionals in the fields of toxicology, medicine, pharmacology, food, and drugs.
    Type of Medium: Online Resource
    Pages: XVIII, 768 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811978340
    URL: https://doi.org/10.1007/978-981-19-7834-0
    DOI: 10.1007/978-981-19-7834-0
    DDC: 615
    Language: English
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  • 27
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    Online Resource
    Pharmacology of Drug Stereoisomers (2022)
    Singapore :Springer Nature Singapore :
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    Keywords: Pharmacology. ; Medicinal chemistry. ; Pharmaceutical chemistry. ; Biotechnology. ; Biochemical engineering. ; Pharmacology. ; Medicinal Chemistry. ; Pharmaceutics. ; Biotechnology. ; Bioprocess Engineering.
    Description / Table of Contents: Preface -- General principles of chirality -- Quantitative methods of analysing chirality drugs - Chirality and pharmacokinetics -- Drugs regulating the function of peripheral nervous system -- In silico search for chiral drug compounds.
    Abstract: The book is devoted to an important aspect of pharmacology and pharmaceutical chemistry, i.e. the significance of stereoisomerism of drugs for their biological effect from the point of view of their pharmacokinetics, pharmacodynamics and toxicology. The authors review the landmarks in the development of stereochemistry and stereopharmacology. Present-day IUPAC terminology is discussed; general issues of stereoisomerism are considered including separation of racemic mixtures and asymmetric synthesis of isomers, methods of quantifying the isomers of a drug in biological material. The authors put special emphasis on general problems of the influence of stereoisomerism on pharmacological and adverse effects of drugs. A classification of drugs based on stereochemical properties of their isomers is proposed. Possibilities of interaction of stereoisomers in racemic mixtures are discussed. A considerable portion of the book is devoted to pharmacological action of the main groups of drugs whose structure includes asymmetric atoms (that is, drugs with several isomers). Detailed attention is paid to advisability of developing single isomer drugs and to the specifics of their study at the stage of preclinical and clinical trials.
    Type of Medium: Online Resource
    Pages: XI, 207 p. 174 illus., 6 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811923203
    Series Statement: Progress in Drug Research, 76
    URL: https://doi.org/10.1007/978-981-19-2320-3
    DOI: 10.1007/978-981-19-2320-3
    DDC: 615
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  • 28
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    Online Resource
    Rabies and Rabies Vaccines (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Virology. ; Immunology. ; Pharmacology. ; Virology. ; Immunology.
    Description / Table of Contents: Rabies Life Cycle, Transmission and Pathogenesis -- History of Rabies and Rabies Vaccines -- Rabies vaccines for wildlife -- Human Rabies Vaccines -- Rabies vaccines, prophylactic, Peru -- Rabies Prevention in Asia: Institutionalizing Implementation Capacities -- Passive Immunity in Rabies Prophylaxis -- Rabies Little Virus Against Powerful Innate Immunity -- Novel Rabies Vaccines -- Assessing the potency of inactivated veterinary vaccines and oral live vaccines against rabies -- WHO Perspective on Rabies.
    Abstract: This book reviews the recent advances in rabies research and rabies vaccine development. The reader is introduced to biology and pathology of the virus, causing agents and the history of rabies vaccination. The book presents regional rabies prophylaxis programs and discusses vaccination strategies for wildlife and humans. Further, innate immune response as well as antibody response to rabies are examined. All chapters are written by renowned experts in rabies research, some of them part of the WHO Collaboration Centre for Rabies Surveillance and Research. The book targets researchers and health professionals working in Virology, Veterinary Medicine and Biomedicine. .
    Type of Medium: Online Resource
    Pages: VII, 205 p. 15 illus., 12 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030210847
    URL: https://doi.org/10.1007/978-3-030-21084-7
    DOI: 10.1007/978-3-030-21084-7
    DDC: 615
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  • 29
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    Online Resource
    Principles of Forensic Toxicology (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Forensic sciences. ; Medical jurisprudence. ; Pharmacology. ; Forensic Science. ; Forensic Medicine.
    Description / Table of Contents: Part 1: Introduction -- Post Mortem Forensic Toxicology -- Human Performance Toxicology -- Drug-Facilitated Sexual Assault -- Forensic Drug Testing -- Performance enhancing Drug Testing -- Drug Testing in Pain Management -- Pharmacokinetics and Pharmacodynamics -- Part II. Specimen Preparation -- Spectrophotometry -- Chromatography -- Derivatization -- Immunoassy -- Mass Spectrometry -- Quantitation -- Method Validation -- Measurement Uncertainty and Traceability -- Statistics in Forensic Toxicology -- Part III Analytes -- Alcohol -- Benzodiazapines -- Gammahydroxybutyric acid,- Miscellaneous Central Nervous System Depressants -- Opioids -- Cocanie -- Cannabis -- Amphetamines-Sympathomimetic Amines,- Hallucinogens and Psychedelics -- Antidepressants and Neuroleptics -- Miscellaneous Therapeutic Drugs -- Carbon Monoxide/Cyanide -- Inhalants -- Metals -- Part III Special Topics -- Stability of Drugs of Abuse in Biological Systems -- Postmortem Redistribution of Drugs -- Postmortem Clinical Testing -- Pharmacogenomics -- Hair Drug Testing -- Oral Fluid Testing -- Meconium Drug Testing -- Drugs in Embalmed Tissues.
    Abstract: The fifth edition of the best-selling Principles in Forensic Toxicology continues in the tradition of excellence in academic publishing. With over 10 years of classroom-tested and continually updated content, the new edition contains significant updates and 7 new chapters on new topics including drug-facilitated crimes, derivatization, quantitation, measurement uncertainty/traceability, statistics, oral fluid testing, and drugs in embalmed specimens. Part One covers the major sub-disciplines of forensic toxicology in addition to pharmacological concepts. Part Two addresses specimen preparation, laboratory testing and instrumental analysis, while Part Three discusses common analytes including cocaine, opioids, alcohol, and marijuana. Adopted for courses in many of the top universities for forensic science and used by respected medical examiner’s offices and crime laboratories worldwide, Principles of Forensic Toxicology prepares the next generation of forensic toxicologists and continues to be an important reference in professional practice.
    Type of Medium: Online Resource
    Pages: XIII, 691 p. 188 illus., 23 illus. in color. , online resource.
    Edition: 5th ed. 2020.
    ISBN: 9783030429171
    URL: https://doi.org/10.1007/978-3-030-42917-1
    DOI: 10.1007/978-3-030-42917-1
    DDC: 615
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  • 30
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    Online Resource
    Recent Advances in Therapeutic Drug Monitoring and Clinical Toxicology (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Toxicology. ; Pharmaceutical chemistry. ; Pharmacology. ; Toxicology. ; Pharmaceutics.
    Description / Table of Contents: Therapeutic and toxic concentration of drugs in biological matrices -- Analytical techniques for therapeutic drug monitoring and clinical toxicology -- Plasma therapeutic drug monitoring and clinical toxicology -- Dried blood spots in therapeutic drug monitoring and toxicology -- The role of artificial intelligence in therapeutic drug monitoring and clinical toxicity -- Therapeutic drug monitoring and optimal pharmacotherapy with medicines of narrow therapeutic index -- Therapeutic drug monitoring (TDM) and toxicological studies in alternative biological matrices -- Analyzing data from therapeutic drug monitoring, pharmacokinetics, and clinical toxicology studies -- Reducing toxicity in critically ill patients by using therapeutic drug monitoring -- Quality assurance of samples for therapeutic drug monitoring and clinical toxicology -- Therapeutic drug monitoring and toxicology of anticancer drugs -- Therapeutic drug monitoring and toxicology of immunosuppressant -- Therapeutic drug monitoring and toxicology: relevance of measuring metabolites -- Recent advances in nanosensors for Therapeutic Drug Monitoring (TDM) -- Organ toxicity by immunosuppressive drugs in solid organ transplantation -- Artificial intelligence-based techniques to assess drug toxicity in drug induced liver injury (DILI) disease -- Drug dose and therapy individualization -- Models for drug individualization: patient to population level -- Toxicity evaluation of nanomedicine -- Biochemical indices of drug toxicity -- Therapeutic drug monitoring and clinical toxicology: challenges and future directions.
    Abstract: This book gives an overview of therapeutic drug monitoring (TDM) and its clinical application. It also highlights recent advances in toxicological studies, as they relate to therapeutic drug monitoring. This is one of the few books available on the market that covers TDM. Therapeutic drug monitoring (TDM) is a clinical decision-making tool that enables dosage regimen adjustments based on clinical and laboratory measurements. TDM not only involves the measuring of drug concentrations but also interpretation of the results. There is a strong correlation between drug concentrations in body fluids and outcome than between dose and outcome. The chapters include coverage of analytical techniques, pharmacokinetics, therapeutic indices, artificial intelligence and recent advances in toxicological studies. The book fills a gap in published literature and provides reliable information on; Analytical techniques in TDM and clinical toxicology TDM and pharmacokinetic studies TDM of drugs with narrow therapeutic indices Artificial intelligence in TDM and clinical toxicology Future directions and challenges .
    Type of Medium: Online Resource
    Pages: XVIII, 381 p. 43 illus., 41 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031123986
    URL: https://doi.org/10.1007/978-3-031-12398-6
    DOI: 10.1007/978-3-031-12398-6
    DDC: 615
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  • 31
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    From PharmD to Industry : A Fellowship Guide (2023)
    Cham :Springer Nature Switzerland :
    Details
    Keywords: Pharmacology. ; Pharmacy. ; Career education. ; Pharmacology. ; Pharmacy. ; Career Skills.
    Description / Table of Contents: Fellowship 101 -- The First Professional Year (P1) -- The Second Professional Year (P2) -- The Third Professional Year (P3) -- The Fourth Professional Year (P4) -- Midyear Applications, Interviews, and Receptions -- Transitioning from Student to Fellow -- Navigating the Virtual Landscape.
    Abstract: For many Doctor of Pharmacy (PharmD) candidates, post-graduate training is a highly prestigious and sought after experience that can further one’s pre-existing education. Some of these post-graduate training opportunities include but are not limited to pharmacy residencies, pharmaceutical industry fellowships, and PhD/Masters programs. There is a large gap in the current Doctor of Pharmacy curriculum about pharmaceutical industry fellowship programs and potential pharmaceutical industry opportunities. Through the eyes of current industry fellows and professionals, this book serves as a resource to learn more about fellowship opportunities and their respective application processes. In addition, this manual aims to provide a clear and concise roadmap to achieving a career in industry through a fellowship program. Whether you are a current student pharmacist, post-graduate pharmacy trainee (pharmacy resident), or industry professional, this manual addresses the current landscape of industry fellowship programs, an overview of industry opportunities, and a glimpse into what being a fellow entails. Readers of this book can expect to gain: An overview of pharmaceutical industry fellowship programs and opportunities Helpful advice and insight from current fellows and industry professionals A streamlined pathway to navigating the fellowship application process An understanding of the journey from being a student, to achieving a fellowship, to becoming an industry professional This book bridges the gap in education surrounding pharmaceutical industry fellowships and pharmacy careers in industry and increases access to first-hand information and real-world perspectives of current professionals to provide a firm foundation for those interested in pursuing a career in industry or learning more about fellowship programs.
    Type of Medium: Online Resource
    Pages: XIX, 92 p. 4 illus., 3 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031357879
    Series Statement: SpringerBriefs in Pharmaceutical Science & Drug Development,
    URL: https://doi.org/10.1007/978-3-031-35787-9
    DOI: 10.1007/978-3-031-35787-9
    DDC: 615
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  • 32
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    Online Resource
    Contract Research and Development Organizations-Their History, Selection, and Utilization (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Pharmacy. ; Pharmacology. ; Pharmacy.
    Description / Table of Contents: Introduction -- History of CROs: Including CRO Snapshots and a CRO Genealogy Chart -- The Pharmaceutical Development Process & Testing Requirements -- The Medical Device Development Process & Testing Requirements -- Functions and Types of CROs -- Labs in China and India -- Selection of CROs -- Study Directors and PIs -- Nuts and Bolts of Study Performance SCG/CBS -- Electronic Reporting Requirements (SEND & eCTD) -- Study and Project Monitoring -- Contracting, Pricing, and Cost of Works Performed by CROs -- Consultants and their Role -- Building Relationships: Maximizing your return on Expectations with a CRO -- Common Problems and their Solutions -- Appendices: A Toxicology Labs B Medical Device Labs C Phase I Labs D Analytical Labs E GMP Contract Facilities F Formulation G Dosage Forms H Clinical Testing I Regulatory Services J Forms and Checklists -- K Specialized Services -- L Consultants Known to be In-Practice -- Index. .
    Abstract: This volume provides a complete update of all the materials in prior volumes on the subject (including current directories to testing labs and other support establishments worldwide), while adding substantial new material on the following topics: · The history of CROs, including snapshots of CROs and a genealogy chart making clear where they came from and where they went. · Study directors and principal investigators. · The nuts and bolts of study performance. · Electronic reporting requirements – SEND and eCTD (required for NDA, BLA, ANDA, and IND submissions). · Consultants and their roles. · An expanded examination of common problems and their solutions. This book boasts complete directories to the global universe of operating labs – where they are, how to contact them, and what they do (including special capabilities). Additionally, checklists for qualifying labs and manufacturing facilities – and for auditing studies and projects at such facilities – are included. It is directed at those in industry (specifically directed at those working for companies using CRO services) but will also be of interest to scientists or administrators working in research organizations themselves. In this case, the contents of this new work are essential to the target reader because the work, regulations, and actors (CROs) have evolved and changed at a rapid pace in the 10 years since the earlier volume that the author published. Likewise, the companies using these services have come to all be almost completely dependent on outsourcing. The earlier texts remain the only source of their kind (paper or electronic) on the field and the only noncommercial guide to the global industry and this volume provides a complete update.
    Type of Medium: Online Resource
    Pages: XIII, 519 p. 19 illus., 1 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030430733
    URL: https://doi.org/10.1007/978-3-030-43073-3
    DOI: 10.1007/978-3-030-43073-3
    DDC: 615
    Language: English
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    Toll-like Receptors in Health and Disease (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Immunology. ; Inflammation. ; Pharmacology. ; Immunology. ; Inflammation.
    Description / Table of Contents: Intracellular TLRs (TLR3, TLR7, and TRL9) in host defense or TLRs in mast cells -- Toll-like receptors as drug targets in the intestinal epithelium -- Innate immune memory-priming, tolerance and exhaustion-in health and disease -- TLRs in brain immunity -- TLRs in cerebrovascular diseases -- TLRs in stem cells or progenitor cells -- TLRs in adaptive immunity -- Overview on TLRs in immunity -- TLR10 and its role in immunity.
    Abstract: The current book is focussed on the Toll-like receptors (TLRs), which are the first pattern recognition receptors (PRRs) discovered in humans. For example, TLR4 was first recognized in humans in 1997 as a PRR recognizing the Gram-negative bacterial lipopolysaccharide (LPS). This discovery revolutionized the field of innate immunity and filled the long-standing gap in the pathogen recognition by the immune system. Now, it is well established that humans have 10 (TLR1-TLR10) and mice have 12 (TLR1-TLR13) functional TLRs, excluding TLR10 that is present as a defective pseudogene. TLRs are present as both membrane-bound extracellular (TLR1, TLR2, TLR4, TLR5, TLR6, and TLR10) and intracellular (TLR3, TLR7, TLR8, and TLR9) PRRs in humans, which identify different pathogen or microbe-associated molecular patterns (PAMPs or MAMPs) and death or damage-associated molecular patterns (DAMPs) released by the host cells. A lot of development in the TLR biology has occurred in last 24 years since there first discovery in humans. The book is intended to describe their role in the host defence, human reproduction, non-infectious sterile inflammatory conditions, including brain immunity and cerebrovascular diseases, signaling mechanisms, adaptive immunity, and their targeting for drug development.
    Type of Medium: Online Resource
    Pages: VIII, 314 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031065125
    Series Statement: Handbook of Experimental Pharmacology, 276
    URL: https://doi.org/10.1007/978-3-031-06512-5
    DOI: 10.1007/978-3-031-06512-5
    DDC: 615
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    Prebiotics, Probiotics and Nutraceuticals (2022)
    Singapore :Springer Nature Singapore :
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    Keywords: Pharmacology. ; Clinical medicine Research. ; Medicine Research. ; Biology Research. ; Pharmacology. ; Clinical Research. ; Biomedical Research.
    Description / Table of Contents: Chapter 1. Potentiality of Probiotics in Inactivation of Tetrodotoxin -- Chapter 2. Therapeutic Strategy for the Deterrence of COVID-19 with Relevance to Probiotics -- Chapter 3. Plant based Bioactive compounds in Cancer Therapeutics -- Chapter 4. Therapeutic Strategy for the Deterrence of COVID-19 with Relevance to Probiotics -- Chapter 5. Probiotics as efficacious therapeutic option for treating gut-related diseases: molecular and immunobiological perspectives -- Chapter 6. The progressive development of probiotics, prebiotics, synbiotics research, and its multipurpose use in the ornamental fishery -- Chapter 7. The commercial perspective of probiotics, and bioremediating components in aquaculture pond management: A Case Study -- Chapter 8. Prebiotics as promising therapeutics for treating gut-related disorders : Biochemical and Molecular Perspectives -- Chapter 9. Prebiotics and Probiotics as Functional Foods: Prospect and Promises in Metabolic Diseases. Chapter 10. Implications of probiotics and prebiotics on immune functions -- Chapter 11. Recent Trends in Natural Medicines and Nutraceuticals Research -- Chapter 12. Nutraceuticals-are alternative to modern medicines- Chapter 13. Socio-Economic Study of Prospective of probiotic, prebiotic and synbiotic for sustainable development of aquaculture in Indian Sunderban -- Chapter 14. Drosophila melanogaster as an in-vivo model for the investigation of host microbiota interaction -- Chapter 15. Prospectives of Prebiotics, Probiotics and Synbiotics for Sustainable Development of Aquaculture.
    Abstract: The book titled ‘Prebiotics, Probiotics and Nutraceuticals’ is expected to direct many emerging research pathwaysneed at local and global levels for nutrition and food supplements for developing immunity for healthy life. This volume incorporates sixteen seminal papers on issue based research and their practical applications covering latest information and progress on different area of nutritional supplement research fight against disease. The book highlights the frontier issues and applications in nutritional biotechnology with wide coverage of the themes like Potentiality of Probiotics in Inactivation of Tetrodotoxin, Therapeutic Strategy for the Deterrence of COVID-19 with Relevance to Probiotics and Prospectives of Prebiotics, Probiotics and Synbiotics for Sustainable Development in Aquaculture.Plant based Bioactive compounds in Cancer Therapeutics, Recent Trends in Natural Medicines and Nutraceuticals Research, Probiotics as efficacious therapeutic option for treating gut-related diseases: molecular and immune-biological perspectives, The progressive development of probiotics, prebiotics, synbiotics research, and its multipurpose use in the ornamental fishery, The commercial perspective of probiotics, and bioremediating components in aquaculture pond management: A Case Study andPrebiotics as promising therapeutics for treating gut-related disorders : Biochemical and Molecular Perspectives. Prebiotics and Probiotics as Functional Foods: Prospect and Promises in Metabolic Diseases, Implications of probiotics and prebiotics on immune functions. Recent Trends in Natural Medicines and Nutraceuticals Research, Nutraceuticals are alternative to modern medicines, Socio-Economic Study of Prospective of probiotic, prebiotic and synbiotic for sustainable development of aquaculture in Indian Sunderban. This book will be very useful for the scholars, biotechnologists, agricultural scientists, nutritionist, medical doctors, researchers, teachers and students in the emerging field of biotechnology.
    Type of Medium: Online Resource
    Pages: XVI, 340 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811689901
    URL: https://doi.org/10.1007/978-981-16-8990-1
    DOI: 10.1007/978-981-16-8990-1
    DDC: 615
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    Botulinum Toxin Treatment in Surgery, Dentistry, and Veterinary Medicine (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Surgery. ; Dentistry. ; Veterinary medicine. ; Neurology . ; Orthopedic surgery. ; Pharmacology. ; Surgery. ; Dentistry. ; Veterinary Science. ; Neurology. ; Surgical Orthopedics.
    Description / Table of Contents: 1. History of development of botulinum toxin therapy in medical and surgical fields -- 2. Molecular structure and mechanisms of action of botulinum toxins as it pertains to clinical symptoms -- 3. Types of toxins in commercial use, their similarities and differences -- 4. A review of current Botulinum toxin treatment indications in medical field. - 5. Mechanisms of Analgesic effects of botulinum neurotoxins -- 6. Botulinum toxin treatment in Head and neck surgery -- 7. Botulinum toxin treatment of thoracic and abdominal surgery -- 8. Botulinum Toxin A in Abdominal Wall Reconstruction -- 9. Use of Botulinum toxin A in post-mastectomy breast reconstruction -- 10. Botulinum Toxins for Treatment of Pain in Orthopedic Disorders -- 11. Botulinum toxin for pediatric patients, Who? For what? When? -- 12. Botulinum Toxin Treatment in Plastic Surgery -- 13. Botulinum Toxin Treatment in Ophthalmology and Ophthalmic surgery -- 14. Botulinum Toxin Treatment in Gastrointestinal Disorders -- 15. Botulinum Toxin Treatment in Urological Disorders -- 16. Botulinum Toxin Treatment in Dentistry -- 17. Botulinum toxin treatment in Veterinary Medicine - Clinical implications -- 18. Future Perspectives of Botulinum Toxin Application In Dentistry.
    Abstract: All books on the market which have been written on the subject of botulinum toxin therapy focus on treatment of hyperactive movement disorders, autonomic dysfunction (bladder, sweat and salivary glands) and some pain indications (migraine). Reference to pre-or post -surgical indications are brief and often out-dated. No book has information on dentistry or veterinary medicine. This book provides up-to-date information on botulinum toxin therapy in surgical fields. It is also the only book in the market that provides information on botulinum toxin therapy in dentistry and veterinary medicine and furnishes the latest information. Botulinum Toxin Treatment in Surgery, Dentistry, and Veterinary Medicine appeals to many disciplines including surgery, dentistry and veterinary medicines well as appealing to neurologists and internists.
    Type of Medium: Online Resource
    Pages: VIII, 398 p. 70 illus., 60 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030506919
    URL: https://doi.org/10.1007/978-3-030-50691-9
    DOI: 10.1007/978-3-030-50691-9
    DDC: 615
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    Metabolomics and Its Impact on Health and Diseases (2023)
    Cham :Springer International Publishing :
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    Keywords: Pharmacology. ; Biochemical markers. ; Cytology. ; Analytical biochemistry. ; Pharmacology. ; Biomarkers. ; Cell Biology. ; Analytical Biochemistry.
    Description / Table of Contents: Preface -- Practical Aspects of NMR-Based Metabolomics -- Compound Identification in Mass Spectrometry-Based Metabolomics -- METABOLOMICS USING NMR – Avoiding the ‘Black-Box’ -- Natural products drug discovery: on silica or in silico?- Quantitative NMR Methods in Metabolomics -- Advancements in pulsed stable isotope resolved metabolomics -- Metabolomics in Cell Biology -- NMR-based metabolomics to evaluate individual response to treatments -- Pharmacometabolomics of Asthma as a road map to Precision Medicine -- Prospective metabolomic studies in precision medicine -- Chemotherapy-induced Peripheral Neuropathy -- Metabolomics of Respiratory Diseases.
    Abstract: This volume of the Handbook of Experimental Pharmacology, which celebrated its 100th anniversary in 2019, addresses the rapidly growing and evolving field of metabolomics. It has been compiled and designed to broaden and enrich your understanding as well as simplify a complicated picture of the diverse field of metabolomics. This is accomplished by chapters from experts in the field on basic principles as well as reviews and updates of analytical techniques. The variety and different perspectives of the NMR approaches are described in the chapters By David Wishart, Daniel Raftery and Ryan McKay, while mass spectrometry advances are covered by Charles R. Evans and Stefan Kempa. This book also reflects the state of the art in the application of metabolomics to cell biology (Marta Cascante and Ulrich Guenther) and chapters that share insights into the application of metabolomics in various diseases (Paola Turano and Claudio Luchinat, Rachel S. Kelly and Jessica Lasky-Su, Paige Lacy, and Angela Rogers. Relationships of metabolomics with drugs are highlighted by Robert Verpoorte (natural products drug discovery), by Oscar Millet and by Turano and Luchinat (perspectives in precision medicine) and by Daniel L. Hertz (drug-induced peripheral neuropathy). From the above list of diverse topics, we believe this book has interdisciplinary appeal and scholars with an interest in the role of metabolomics in achieving precision medicine will find it of particular or special interest.
    Type of Medium: Online Resource
    Pages: VIII, 384 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031268595
    Series Statement: Handbook of Experimental Pharmacology, 277
    URL: https://doi.org/10.1007/978-3-031-26859-5
    DOI: 10.1007/978-3-031-26859-5
    DDC: 615
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    Structure and Health Effects of Natural Products on Diabetes Mellitus (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Botanical chemistry. ; Bioorganic chemistry. ; Pharmacology. ; Plant Biochemistry. ; Bioorganic Chemistry.
    Description / Table of Contents: Chapter 1. Introduction of diabetes melitus and future prospects of natural products on diabetes melitus -- Chapter 2. Anoverview of hypoglycemic modern drugs -- Chapter 3. An overview of hypoglycemic biological drugs -- Chapter 4. An overview of hypoglycemic traditionaldrugs -- Chapter 5. Glycosides from natural sources in the treatment of diabetes mellitus -- Chapter 6. Isolation and Structure Elucidation of Hypoglycemic Compounds -- Chapter 7. Structural Characterization and Health Effects of Polysaccharides from Momordica charantia on Diabetes Mellitus -- Chapter 8. Effects of polysaccharides on reducing blood glucose based on gut microbiota alteration -- Chapter 9. An Overview of Polysaccharides and the influencefactors of Hypoglycemic Activity -- Chapter 10. Plant Secondary Metabolites with α-Glucosidase Inhibitory Activity. - Chapter 11. Rhinacanthin-C and Its Potential to Control Diabetes Mellitus -- Chapter 12. Regeneration of beta cells by inhibition of pro-apoptotic proteins through phytocompound in STZ induced diabetic albino wistar rats-invivo and insilico approach. - Chapter 13. Nitrogenous Compounds from Plant Origin in Management of -- Chapter 14. Plant Alkaloids with Antidiabetic Potential -- Chapter 15. The role of Alkaloids in the Management of Diabetes Mellitus -- Chapter 16. Traditional Indian Herbs for the Management of Diabetes Mellitus and their Herb-Drug Interaction Potentials: An Evidence-Based Review -- Chapter 17. Role of Micronutrients and Trace elements in Diabetes mellitus: A Review.
    Abstract: The purpose of this book is to introduce the classified chemical components of hypoglycemic compounds in natural products, summarize the recent research progress of natural products with hypoglycemic activity in the past 20 years, and provide the original analysis and development opinions of relevant scholars. Hypoglycemic compounds are to target diabetes mellitus, an important public health problem, one of four priority noncommunicable diseases (NCDs) targeted for action by world leaders. Diabetes mellitus is a common endocrine and metabolic disease, which not only causes physiological damage to patients' kidneys, cardiovascular and cerebrovascular vessels, peripheral blood vessels, nerves and eyes, but also causes mental and psychological pressure to patients. Due to the evidence that traditional medicine and natural herbal formula have advantages in treating diabetes, natural products with hypoglycemic activity have been studied extensively in recent years and have been accepted by many scholars all over the world. This book focuses on the progress on the study of the structure, hypoglycemic activities, structure-activity relationships and mechanism of a wide range of polysaccharides, flavonoids, saponins, alkaloids, terpenoids, polyphenols and other constituents. It will help students and researchers to understand current approaches and progress in the treatment of diabetes with natural products, which may also be beneficial to develop new hypoglycemic drugs.
    Type of Medium: Online Resource
    Pages: VIII, 307 p. 85 illus., 16 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811587917
    URL: https://doi.org/10.1007/978-981-15-8791-7
    DOI: 10.1007/978-981-15-8791-7
    DDC: 615
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    Pharmacology of Immunosuppression (2022)
    Cham :Springer International Publishing :
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    Keywords: Pharmacology. ; Human physiology. ; Immunology. ; Surgery. ; Pharmacology. ; Human Physiology. ; Immunology. ; Surgery.
    Description / Table of Contents: Review of the Pathophysiology of the Alloimmune response -- A Comprehensive Review of Calcineurin Inhibitors Used for Immunosuppression in Cardiac Transplantation -- Anti-proliferative Agents -- Mechanistic Target of Rapamycin (mTOR) Inhibitors -- Corticosteroids -- Induction therapy and antibodies -- Immunosuppression and Heart Transplantation -- Immunosuppression and Lung Transplantation -- Immunosuppression and renal transplant recipients -- Immunosuppression in Rheumatologic and Auto-immune Disease -- Immunosuppression in Bone Marrow Transplantation -- Immunosuppression in Multiple Sclerosis and Other Neurologic Disorders -- Novel immunosuppressive agents for the treatment of organ transplants -- Adverse Effects of Immunosuppression: Infections -- Malignancy: An Adverse Effect of Immunosuppression -- Adverse Effects of Immunosuppression:Nephrotoxicity, Hypertension and Metabolic Disease.
    Abstract: The goal of this book is to provide a guide and detailed review of immunosuppression in terms of molecular mechanisms of action, side effects and clinical trials that validated their utility. This includes their use in solid organ transplantation, bone marrow transplantation and autoimmune diseases and inflammatory diseases. This book is a critical review of these topics and a vital resource.
    Type of Medium: Online Resource
    Pages: VIII, 348 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031051180
    Series Statement: Handbook of Experimental Pharmacology, 272
    URL: https://doi.org/10.1007/978-3-031-05118-0
    DOI: 10.1007/978-3-031-05118-0
    DDC: 615
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    Evidence Based Validation of Traditional Medicines : A comprehensive Approach (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Medical microbiology. ; Medicinal chemistry. ; Pharmacovigilance. ; Pharmacology. ; Medical Microbiology. ; Medicinal Chemistry. ; Drug Safety and Pharmacovigilance.
    Description / Table of Contents: Chapter 1. Global Approach for Drug Discovery and Development from Indian Traditional Medicine -- Chapter 2. Bioactive Natural Leads TargetingCancer Cell Metabolism -- Chapter 3. Omics Technologies and Development of Anti-diabetic Therapies from Prospective Natural Products -- Chapter 4. Amaryllidaceae Alkaloids as Anti-inflammatory Agents Targeting Cholinergic Anti-inflammatory Pathway: Mechanisms and Prospects -- Chapter 5. Neurodegenerative Diseases and Small Molecule Protein Chaperone Activator of Natural Origin -- Chapter 6. Role of Phytomolecules on the Basic Biology of Aging -- Chapter 7. Role of phytomedicine in alleviating oxidative stress mediated vascular complications in diabetes -- Chapter 8. Plant Based -Secretase (BACE-1) Inhibitors: A Mechanistic Approach to Encounter Alzheimer's Disorder -- Chapter 9. Bioactive Compounds of Mangroves as Potent Drug and in Nanoparticle Synthesis - Play a Pivotal Role in Combating Human Pathogens. Chapter 10. Medicinal Plants: A Rich Source of Bioactive Molecules Used in Drug Development -- Chapter 11. Cell-based Assays in Natural Product-based Drug Discovery -- Chapter 12. Allelochemicals: An Emerging Tool for Weed Management -- Chapter 13. Secondary Metabolites of Higher Plants as Green Preservatives of Herbal Raw Materials and Their Active Principles During Postharvest Processing -- Chapter 14. Importance of Chromatography Techniques in Phytomedicine Research -- Chapter 15. Reverse Pharmacology – A Tool for Drug Discovery From Traditional Medicine -- Chapter 16. Role of Modern Biological Techniques in Evidence-Based Validation of Ayurvedic Herbometallic Preparations -- Chapter 17. HPTLC Fingerprinting analysis of Phytoconstituents from Indigenous Medicinal Plants -- Chapter 18. Climate Change,Geographical Location and Other Allied Triggering Factors Modulate the Standardization and Characterization of Traditional Medicinal Plants: AChallenges and Prospect for Phyto-Drug Development -- Chapter 19. Molecular Docking Studies of Plant-Derived Bioactive Compounds: A Comprehensive in silico Standardization Approach -- Chapter 20. Standardization and Quality Evaluation of Botanicals with Special Reference to Marker Components -- Chapter 21. Analytical Standardization of Haridra Formulation by UV-VIS Spectrophotometry and RP-HPLC -- Chapter 22. Ethnobotanical survey: the foundation to evidence based validation of medicinal plants -- Chapter 23. Phytotherapeutics: The Rising Role of Drug Transporters in Herb-Drug Interactions with Botanical Supplements -- Chapter 24. An Insight into Herb Interactions: Clinical Evidence Based Overview -- Chapter 25. Pharmacovigilance of Herbal Medicines: An Overview -- Chapter 26. Herbal Drugs: Efficacy, Toxicity and Safety Issues -- Chapter 27. Herbal Drug Patenting -- Chapter 28. Safety and Regulatory Issues on Traditional Medicine Entrusted Drug Discovery -- Chapter 29. Pharmacovigilance of Herbal Medicine: An Evolving Discipline -- Chapter 30. Toxicity Studies Related to Medicinal Plants -- Chapter 31. Herb-Drug Interactions -- Chapter 32. Plant Based Traditional Herbal Contraceptive Use in India: Safety and Regulatory Issues -- Chapter 33. Traditional Medicine Stability and Pharmacokinetic Issue -- Chapter 34. Pharmacovigilance: Methods in developing the safety and acceptability of traditional medicines -- Chapter 35. Zoopharmacognosy (Plant-Animal Interaction) -- Chapter 36. Significance of Stability and Pharmacokinetic issues in Traditional Medicine -- Chapter 37. Pharmaceutical Formulations Development Based on the Polymers Obtained from Edible Plants: An Excellent Approach for the Betterment in Health Care Services -- Chapter 38. Evaluation of bioactivity of green nanoparticles synthesized from traditionally used medicinal plants: a review -- Chapter 39. Physicochemical, Micromeritics, Biomedical and Pharmaceutical Applications of Assam Bora Rice Starch -- Chapter 40. Natural Excipients in Pharmaceutical Formulations -- Chapter 41. A Wonder Plant Withania: Pharmacological and Chemical Perspectives -- Chapter 42. Immunomodulators and Phyto Drugs -- Chapter 43. Combined Effects of Plant Extracts on Ovarian Cell Functioning -- Chapter 44. Pterocarpussantalinus: A Wonder Gift of Nature -- Chapter 45. Phytochemicals And Investigations On Traditionally Used Medicinal Mushrooms -- Chapter 46. A Review On Investigational Studies Of Marine Macroalgae Spogomorpha Indica L -- Chapter 47. Validation of Traditional Claim of Oxalis debilis Kunth., An Ethnomedicinal Plant from North-eastern Region of India -- Chapter 48. Traditional Herbal Medicine Practiced in Plateau-Fringe and Rarh Districts of West Bengal, India -- Chapter 49. Pharmacology and Mechanisms of Natural Medicine in Treatment of Type 2 Diabetes Mellitus -- Chapter 50. Indian Traditional Herbs and Alzheimer’s Disease: Integrating Ethnobotany and Phytotherapy. .
    Abstract: The demand for traditional medicines, herbal health products, herbal pharmaceuticals, nutraceuticals, food supplements and herbal cosmetics etc. is increasing globally due to the growing recognition of these products as mainly non-toxic, having lesser side effects, better compatibility with physiological flora, and availability at affordable prices. In the last century, medical science has made incredible advances all over the globe. In spite of global reorganization and a very sound history of traditional uses, the promotion of traditional medicine faces a number of challenges around the globe, primarily in developed nations. Regulation and safety is the high concern for the promotion of traditional medicine. Quality issues and quality control, pharmacogivilane, scientific investigation and validation, intellectual property rights, and biopiracy are some key issues that restrain the advancement of traditional medicine around the globe. This book contains diverse and unique chapters, explaining in detail various subsections like phytomolecule, drug discovery and modern techniques, standardization and validation of traditional medicine, and medicinal plants, safety and regulatory issue of traditional medicine, pharmaceutical excipients from nature, plants for future. The contents of the book will be useful for the academicians, researchers and people working in the area of traditional medicine. .
    Type of Medium: Online Resource
    Pages: XII, 1151 p. 378 illus., 125 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811581274
    URL: https://doi.org/10.1007/978-981-15-8127-4
    DOI: 10.1007/978-981-15-8127-4
    DDC: 615
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    From Obesity to Diabetes (2022)
    Cham :Springer International Publishing :
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    Keywords: Pharmacology. ; Metabolism Disorders. ; Pharmacology. ; Metabolic Disease.
    Description / Table of Contents: Part I Obesity. Epidemiology of Obesity -- The Circadian Clock and Obesity -- Nutrition and Microbiome -- From Obesity to Diabetes: The Role of the Adipose Organ -- Targeting Epicardial Fat in Obesity and Diabetes Pharmacotherapy -- The Enteroendocrine System in Obesity -- Insights from Studies of White Adipose Tissue Using Single-Cell Approaches -- Obesity-Related Insulin Resistance: The Central Role of Adipose Tissue Dysfunction -- Obesity, Senescence, and Senolytics -- Obesity and Obstructive Sleep Apnea -- Part II Diabetes and Complications. Inter-Organ Crosstalk in the Development of Obesity-Associated Insulin Resistance -- Islet Inflammation and β Cell Dysfunction in Type 2 Diabetes -- NAFLD and NASH: The Metabolically Diseased Liver -- Diabetic Kidney Disease: From Pathogenesis to Novel Treatment Possibilities -- Diabetic Peripheral Neuropathy -- Part III Lifestyle Modifications and Future Treatments. Weight Loss Strategies -- Physical Activity, Obesity and Weight Loss Maintenance -- Bariatric/Metabolic Surgery -- Drugs for Treating Obesity -- Novel Drugs for Diabetes Therapy -- Novel Approaches to Restore Pancreatic Beta-Cell Mass and Function -- Precision Medicine and Obesity -- Targeting the Enteroendocrine System for Treatment of Obesity.
    Abstract: Obesity is a major risk factor for the development of type 2 diabetes and its associated complications, a major socio-economic burden for health care systems. The worldwide prevalence of obesity doubled since 1980 and as a consequence the number of patients with diabetes has been continuously rising with more than 450 Mio. people suffering from this disease at the present time. Substantial progress has been made in understanding the molecular pathways leading from excessive fat accumulation to metabolic perturbation and finally diabetes manifestation. This edition of the "Handbook of Experimental Pharmacology" aims to analyze new insight into the pathophysiology of obesity, to decipher the complex links to diabetes and its complications, and to collect most recent information on new strategies for prevention and treatment of obesity and diabetes.
    Type of Medium: Online Resource
    Pages: VIII, 513 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030999957
    Series Statement: Handbook of Experimental Pharmacology, 274
    URL: https://doi.org/10.1007/978-3-030-99995-7
    DOI: 10.1007/978-3-030-99995-7
    DDC: 615
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    Immunity Boosting Medicinal Plants of the Western Himalayas (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Natural products. ; Botany. ; Ethnology. ; Pharmacology. ; Natural Products. ; Plant Science. ; Ethnography.
    Description / Table of Contents: 1. Introduction to Western Himalayas -- 2. Achillea millefolium L., Common Yarrow -- 3. Arisaema jacquemontii Blume, Jacquemont's Cobra Lily -- 4. Species of Arnebia genus found in the western Himalayas -- 5. Species of the Berberis genus found in the western Himalayas -- 6. Dactylorhiza hatagirea (D.Don) Soo – Himalayan Marsh Orchid -- 7. Fritillaria roylei Hook.f.: Himalayan Fritillary -- 8. Gentiana kurroo Royle: Himalayan Gentian -- 9. Habenaria intermedia D.Don and Habenaria edgeworthii Hook., f. ex Collett.: The Western Himalayan medicinal Plants -- 10. Humulus lupulus L.: Beer plant -- 11. Inula racemosa Hook. f. – Puskarmool: Its ethnobotanical uses, phytochemicals and pharmacological activities -- 12. Juniperus recurva Buch.-Ham. ex D.Don and Juniperus squamata D. Don: Himalayan Juniper -- 13. Lancea tibetica Hook.f. & Thomson: Ethnobotany, phytochemistry and pharmacology -- 14. Malaxis muscifera (Lindley) O. Kuntze. and Malaxis acuminata D. Don.: Jeevak -- 15. Picrorhiza kurroa Royle ex Benth.: Kutki -- 16. Species of the genus Polygonatum found in the Western Himalayas -- 17. Species of the genus Rhodiola found in the Western Himalayas -- 18. Saussurea lappa C.B. Clarke: Kushta/Kut -- 19. Saussurea lappa C.B. Clarke: Kushta/Kut -- 20. Species of the genus Selinum found in the western Himalayas -- 21. Swertia chirayita (Roxb. ex Flem.): Chirayata/Chiretta -- 22. Taxus wallichiana Zucc.: The Himalayan yew -- 23. Tribulus terrestris L.: Gokshur /Gokharu -- 24. Species the Genus Viola found in Western Himalayas.
    Abstract: This book presents a comprehensive guide to traditional immunity-boosting medicinal plants of the Himalayas, their traditional uses, phytochemistry, pharmacology, diversity, conversation, biotechnology, toxicology, as well as future prospective. All the chapters cover the latest advances in ethnobotany, phytochemistry, biochemistry, and biotechnology. The book offers a valuable asset for researchers and graduate students of chemistry, botany, biotechnology, microbiology, and the pharmaceutical sciences. The main purpose of the present book is to draw on the rich culture, folklore, and biodiversity of immunity-boosting medicinal plants of the Western Himalayas, with particular emphasis on the Indian Trans-Himalayan and Western Himalayan region. All the plants included in the present book are extensively used by the local tribes and people for their health-promoting properties from ancient times. This book will be a substantial contribution to the knowledge of the region and the country. Also, the book will be very useful to scientists, graduates, and undergraduates, along with researchers in the fields of natural products, herbal medicines, ethnobotany, pharmacology, chemistry, and biology. Further, it is an equally significant resource for a person working in different traditional medicinal systems; doctors (especially those engaged in Ayurveda, Chinese traditional medicinal system, Amchi, and allopathy); the pharmaceutical industry (for drug design and synthesis); biochemistry and biotechnology sciences; and the agricultural sciences. .
    Type of Medium: Online Resource
    Pages: XIX, 609 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811995019
    URL: https://doi.org/10.1007/978-981-19-9501-9
    DOI: 10.1007/978-981-19-9501-9
    DDC: 615
    Language: English
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    Online Resource
    Nanoformulations in Human Health : Challenges and Approaches (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Therapeutics. ; Pharmacology. ; Therapeutics.
    Description / Table of Contents: Nano-technological Platforms and Manipulations for the Emerging Ocular Manifestations -- Phytonanomedicines as Topical Alternatives for the Treatment of Skin Cancer -- Nano-sized Labile and Particulate Ingredients in Topical Formulations: A Strategic Approach Against Photoageing and Photocarcinogenisis -- Application of Biocompatible Nanocarriers in Glaucoma: Challenges and Advances -- Nano-carriers for Natural Therapeutics in the Management of Neuropathic Pain -- Advances in the Delivery of Therapeutic Peptides -- Nanoformulations and Their Role in Colon Targeting -- Theranostic Nanoformulations: Merging Diagnostics and Therapeutics -- The Role of Nanoformulations in Nose-To-Brain Drug Delivery -- Cubic Lyotropic Liquid Crystalline Nanostructures: A Versatile Platform for Delivery -- Preformulation Challenges: The Concept Behind the Selection, Design, and Preparation of Nanoformulations -- Nanoethosomes for Topical Fungal Therapeutics -- Comparison of Therapeutic Efficiency of Nanoformulations of Curcumin vs. Tetrahydrocurcumin in Various Disorders -- Nanomedicinal Approaches of Phytotherapeutics to Treat Alzheimers Disease -- Nanoparticulate Approaches to Exploit the Pathophysiology of Rheumatoid and Osteoarthritis -- Emerging Nanotechnology in Chronic Respiratory Diseases -- Conventional and Non-conventional Approaches of Site-specific Targeting of Therapeutics in Some Infectious Diseases and Metabolic Disorders -- Nanoformulations in Human Health Conditions: The Paradigm Shift -- Magnetic Nanoparticles Nanoformulation for Alternative Therapy of Cancer by Super-paramagnetic Hyperthermia -- Nano-weapons Against Tuberculosis -- Drug-Excipient Interactions in Nanoformulations with Special Focus on Impurity Control per ICH guidelines.
    Abstract: This book is an amalgamation of knowledge, experience, and expertise in various aspects of nanotechnology, by experts who are proficient in designing novel nanoformulations that are used in the treatment of various challenging and prevalent diseases. It is an exhaustive compilation of the multi-faceted arena of nanoformulations and the healthcare system that caters to the needs of academicians, scholars, researchers, etc. The most important aspect of the book covers various types of nanoformulations and their applications in the treatment of communicable and non-communicable diseases. Each chapter focuses on a particular nanoformulation as well as a disease including the pathophysiology of the disease, the current treatment modalities of diseases, the role of nanoformulation in treatment and other future aspects and directions for further work. Coverage includes neuropathic pain, colon targeting, nose-to-brain drug delivery, cancer, arthritis and tuberculosis.
    Type of Medium: Online Resource
    Pages: XVIII, 548 p. 106 illus., 91 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030418588
    URL: https://doi.org/10.1007/978-3-030-41858-8
    DOI: 10.1007/978-3-030-41858-8
    DDC: 615
    Language: English
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    Online Resource
    Emerging Technologies for Nanoparticle Manufacturing (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Nanotechnology. ; Nanochemistry. ; Pharmacology. ; Nanotechnology. ; Nanochemistry.
    Description / Table of Contents: Part 1 Introduction and Biomedical Applications of Nanoparticles -- 1. Introduction to Nanomaterials and Nanotechnology -- 2. Biomedical Applications of Nanoparticles -- Part II-Polymeric Nanoparticles -- 3. Nanocrystallization and Nanoprecipitation Technologies -- 4. Microfluidics Technology for Nanoparticles and Equipment-. 5. Production of Nanocomposites via Extrusion Techniques -- 6. The Use of Supercritical Fluids Technologies for Nanoparticle Production -- 7. Salting out and Ionic Gelation Manufacturing Techniques for Nanoparticles -- 8. Nanogel Synthesis by Irradiation of Aqueous Polymer Solutions -- 9. Cellulose acetate based nanofibers: Synthesis, Manufacturing and Applications -- 10. Production of nanofibers, environmental challenges and solutions -- Part III-Lipid Nanoparticles -- 11. High Pressure Homogenization Techniques for Nanoparticles -- 12. Solvent emulsification evaporation and solvent emulsification diffusion techniques for nanoparticles -- 13. Ultrasound Activated Nanoemulsions -- 14. Multiple Emulsions: Emphasizing on industrial applications -- 15. Membrane techniques for the preparation of nanomaterials -- 16. Self-assembling Lipid Nanoparticles/Nanosystems (SLNN) using Hydrophilic Solvents: Overview and Industrial Uses -- 17. Nanoemulsions – An emerging technology in drug delivery -- Part IV- Metallic Nanoparticles -- 18. Manufacturing techniques for carbon nanotubes, gold nanoparticles and silver nanoparticles -- 19. Radio frequency (RF) plasma-based Synthesis of metallic Nano particles for Biomedical Application -- 20. Techniques for accurate sizing of nanoparticles -- 21. Silver nanoparticles synthesis from cyanobacteria: Environmental and biomedical applications -- 22. Selenium Nanoparticles: Green Synthesis and Exploitation -- Part V- Quality control for nanoparticles -- 23. Practical guidelines for the characterization and quality control of nanoparticlesin the pharmaceutical industry -- Part VI-Challenges in scale-up production of nanoparticles -- 24. Nanomedicine Scale-Up Technologies: Feasibilities and Challenges -- 25. Patent survey on recent technology for nanoparticles -- Part VII-Injectable Nanosystems -- 26. Injectable Nanosystems and Inherent Nano-Serum Interactions -- Part VIII- Future directions and challenges -- 27. Current Challenges and Future Directions in Nanomedicine.
    Abstract: This book provides an overview of nanoparticle production methods, scale-up issues drawing attention to industrial applicability, and addresses their successful applications for commercial use. There is a need for a reference book which will address various aspects of recent progress in the methods of development of nanoparticles with a focus on polymeric and lipid nanoparticles, their scale-up techniques, and challenges in their commercialization. There is no consolidated reference book that discusses the emerging technologies for nanoparticle manufacturing. This book focuses on the following major aspects of emerging technologies for nano particle manufacturing. I. Introduction and Biomedical Applications of Nanoparticles II. Polymeric Nanoparticles III. Lipid Nanoparticles IV. Metallic Nanoparticles V. Quality Control for Nanoparticles VI. Challenges in Scale-Up Production of Nanoparticles VII. Injectable Nanosystems VIII. Future Directions and Challenges Leading scientists are selected as chapter authors who have contributed significantly in this field and they focus more on emerging technologies for nanoparticle manufacturing, future directions, and challenges. .
    Type of Medium: Online Resource
    Pages: XV, 611 p. 155 illus., 117 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030507039
    URL: https://doi.org/10.1007/978-3-030-50703-9
    DOI: 10.1007/978-3-030-50703-9
    DDC: 615
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  • 44
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    Online Resource
    Antiviral Drug Discovery and Development (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Pharmacy. ; Biotechnology. ; Pharmacology. ; Pharmacy. ; Biotechnology.
    Description / Table of Contents: 1 Antiviral Drugs Against Herpesviruses -- 2 An Update on Antiretroviral Therapy -- 3 Structural Insights to Human Immunodeficiency Virus (HIV-1) Targets and their Inhibition -- 4 LEDGINs, Inhibitors of the Interaction between HIV-1 Integrase and LEDGF/p75, are Potent Antivirals with a Potential to Cure HIV Infection -- 5 Moving Fast Towards Hepatitis B Virus Elimination -- 6 Discovery and Development of Antiviral Therapies for Chronic Hepatitis C Virus Infection -- 7 Phytoconstituents as Lead Compounds for Anti-dengue Drug Discovery -- 8 Anti-influenza Drug Discovery and Development: Targeting the Virus and its Host by all -- 9 Search, Identification and Design of Effective Antiviral Drugs against Pandemic Human Coronaviruses -- 10 Peptide Based Antiviral Drugs -- 11 Covalent Antiviral Agents -- 12 Safe-in-Man Broad Spectrum Antiviral Agents -- 13 Exploiting Ubiquitin ligases for Induced Target Degradation as an Antiviral Strategy. .
    Abstract: This book summarizes state-of-the-art antiviral drug design and discovery approaches starting from natural products to de novo design, and provides a timely update on recently approved antiviral drugs and compounds in advanced clinical development. Special attention is paid to viral infections with a high impact on the world population or highly relevant from the public health perspective (HIV, hepatitis C, influenza virus, etc.). In these chapters, limitations associated with adverse effects and emergence of drug resistance are discussed in detail. In addition to classical antiviral strategies, chapters will be dedicated to discuss the non-classical drug development strategies to block viral infection, for instance, allosteric inhibitors, covalent antiviral agents, or antiviral compounds targeting protein–protein interactions. Finally, current prospects for producing broad-spectrum antiviral inhibitors will be also addressed. The book is distinctive in providing the most recent update in the rapidly evolving field of antiviral therapeutics. Authoritative reviews are written by international scientists well known for their contributions in their topics of research, which makes this book suitable for researchers not only within the antiviral research community but also attractive to a broad audience in the drug discovery field. This book covers molecular structures and biochemical mechanisms mediating the antiviral effects, while discussing various ligand design strategies, which include traditional medicinal chemistry, computational chemistry, and chemical biology approaches. The book provides a comprehensive review of antiviral drug discovery and development approaches, particularly focusing on current innovations and future trends.
    Type of Medium: Online Resource
    Pages: XI, 357 p. 142 illus., 64 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811602672
    Series Statement: Advances in Experimental Medicine and Biology, 1322
    URL: https://doi.org/10.1007/978-981-16-0267-2
    DOI: 10.1007/978-981-16-0267-2
    DDC: 615
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  • 45
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    Voltage-gated Ca2+ Channels: Pharmacology, Modulation and their Role in Human Disease (2023)
    Cham :Springer International Publishing :
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    Keywords: Pharmacology. ; Medical genetics. ; Human physiology. ; Pharmacology. ; Medical Genetics. ; Human Physiology.
    Description / Table of Contents: Preface -- Part 1 Modulation -- Cav1.1Calcium Channel Signaling Complexes in Excitation–Contraction Coupling: Insights from Channelopathies -- Mechanisms of Vascular CaV1.2 Channel Regulation During Diabetic Hyperglycemia -- Sympathetic Nervous System Regulation of Cardiac Calcium Channels -- Modulation of CaV1.2 Channel Function by Interacting Proteins and Post-Translational Modifications: Implications in Cardiovascular Diseases and COVID-19 -- Part 2 Pharmacological Approaches -- Pathophysiological Roles of Auxiliary Calcium Channel α2δ Subunits -- Design and Applications of Genetically-Encoded Voltage-Dependent Calcium Channel Inhibitors -- Part 3 Disease insight from channelopathies: consequences for pharmacology and therapeutic strategies -- CACNA1C-Related Channelopathies -- CACNA1D-Related Channelopathies: From Hypertension to Autism -- CACNA1A-Related Channelopathies: Clinical Manifestations and Treatment Options -- CaV3.2 (CACNA1H) in Primary Aldosteronism,- CaV3.3 Channelopathies -- Pathophysiological Roles of Auxiliary Calcium Channel α2δ Subunits.
    Abstract: The aim of this volume is to summarize novel findings on the function, pathophysiology, and regulation of voltage-gated Ca2+ channels and on novel concepts of their pharmacological modulation. Impressive insights into the role of channel function and regulation have come from Ca2+ channelopathies affecting the pore-forming as well as accessory subunits and channel-interacting proteins. Moreover, the long-sought molecular basis for key regulatory pathways have been discovered as well as exciting concepts of their subtype-selective pharmacological modulation.
    Type of Medium: Online Resource
    Pages: XII, 316 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031384370
    Series Statement: Handbook of Experimental Pharmacology, 279
    URL: https://doi.org/10.1007/978-3-031-38437-0
    DOI: 10.1007/978-3-031-38437-0
    DDC: 615
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  • 46
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    Edible Plants in Health and Diseases : Volume II : Phytochemical and Pharmacological Properties (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Food science. ; Medicinal chemistry. ; Pharmacology. ; Food Science. ; Medicinal Chemistry.
    Description / Table of Contents: 1 Zingiber officinale - Its Ethanobotanical Uses, Phytochemistry and Pharmacology -- 2 An Insight in to the Phytochemistry, Traditional uses and Pharmacology of Ziziphus spina-christi (L) Willd. (Sidr): An Edible wild plant of Arabian Peninsula -- 3 Traditional Uses, Phytochemistry and Pharmacological Profile of Salvadora persica Linn -- 4 Phytochemistry, Pharmacology and Applications of Ocimum sanctum (Tulsi) -- 5 Nigella sativa: Its Ethnobotany, Phytochemistry and Pharmacology -- 6 A Review on Ethnomedicinal, Phytochemistry and Pharmacological Activities of Rumex hastatus D. Don -- 7 Chemical Composition and Biological Uses of Crocus sativus L.(Saffron) -- 8 Positive Health Benefits of Saponins from Edible Legumes: Phytochemistry and Pharmacology -- 9 Taraxcum officinale: The Esculent Dandelion as Herbal Medicine -- 10 Arctium lappa: A Review on its Phytochemistry and Pharmacology -- 12 Cichorium intybus: A Comprehensive Review on its Pharmacological Activity and Phytochemistry -- 13 Phytochemical and Pharmacological Properties of Picrorhiza kurroa -- 14 Lady's Purse (Capsella bursa-pastoris L.)-Current perspective on its ethanopharmacological, therapeutic potential and phytochemistry -- 15 Ethnopharmaology, Phytochemistry and Biological Activities of Achillea millefolium: A Comprehensive Review -- 16 A Review on Traditional Uses, Phytochemistry and Pharmacological Activities of Verbascum thapsus -- 17 Acorus calamus - A Review on Its Phytochemical and Pharmacological Profile.
    Abstract: The book provides essential information on some of the promising edible medicinal plants and how these possess both nutritional as well as therapeutic value. The significance of the edible plants in traditional medicine and the importance of the distribution of their chemical constituents are discussed systematically concerning the role of these plants in ethnomedicine in different regions of the world. The current volume deals with the individual plants' phytochemical and pharmacological properties, emphasizing human health. The title would demonstrate the value of natural edible plants and introduce readers to state-of-the-art developments and trends in omics-driven research. This book is a single-source scientific reference to explore the specific factors that contribute to these potential health benefits and discuss how to maximize those potential benefits. Chemists, food technologists, pharmacologists, phytochemists, and all professionals involved with quality control and standardization will find in this book a valuable and updated basis for their work.
    Type of Medium: Online Resource
    Pages: IX, 522 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811649592
    URL: https://doi.org/10.1007/978-981-16-4959-2
    DOI: 10.1007/978-981-16-4959-2
    DDC: 615
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  • 47
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    The Kappa Opioid Receptor (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Pharmacology.
    Description / Table of Contents: From the contents. Preface.-Part I: Molecular aspects of KOR -- Part II: Preclinical research on pharmacology of KOR agonists and antagonists in animals -- Part III: KOR agonists and antagonists in clinical use and in past and present clinical trials.
    Abstract: This book covers the latest knowledge in structure, signaling, and biochemical pharmacology of KOR as well as preclinical research and clinical applications (including clinical phase studies and approved for human use) of KOR compounds. It is divided up into the three parts: Molecular aspects of KOR, Preclinical research on pharmacology of KOR agonists and antagonists in animals and KOR agonists and antagonists in clinical use and in past and present clinical trials. The chapters "Biosensors monitor ligand-selective effects at kappa opioid receptors" and "The role of dynorphin and the kappa opioid receptor in schizophrenia and major depressive disorder: a translational approach" of this book are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Type of Medium: Online Resource
    Pages: XI, 577 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030890742
    Series Statement: Handbook of Experimental Pharmacology, 271
    URL: https://doi.org/10.1007/978-3-030-89074-2
    DOI: 10.1007/978-3-030-89074-2
    DDC: 615
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  • 48
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    Behavioral Neurobiology of GABAB Receptor Function (2022)
    Cham :Springer International Publishing :
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    Keywords: Pharmacology. ; Neurosciences. ; Psychiatry. ; Pharmacology. ; Neuroscience. ; Psychiatry.
    Abstract: It has been almost forty years since Norman G. Bowery discovered and named this “non-GABAA” receptor the GABAB receptor. It has been almost ten years since the last comprehensive book presentation focused on GABAB receptors. The main goal of this book is to provide the field with a contemporary and comprehensive perspective on the GABAB receptor, its physiological relevance, and its therapeutic potential. The volume is organized into introductory and special interest sections presented by experts who study the GABAB receptor from structural, signaling, pharmacologic, physiological, pathophysiological, and therapeutic perspectives. The book aims to appeal to a broad spectrum of biomedical and clinical scientists - any scholars with an interest in GABAB receptor. The editors hope readers find this work to be thought-provoking, instructive, and informative.
    Type of Medium: Online Resource
    Pages: VII, 329 p. 70 illus., 15 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030913359
    Series Statement: Current Topics in Behavioral Neurosciences, 52
    URL: https://doi.org/10.1007/978-3-030-91335-9
    DOI: 10.1007/978-3-030-91335-9
    DDC: 615
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  • 49
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    Marine Biomaterials : Drug Delivery and Therapeutic Applications (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Medicine Research. ; Biology Research. ; Biomaterials. ; Pharmacy. ; Biomedical engineering. ; Pharmacology. ; Biomedical Research. ; Biomaterials. ; Pharmacy. ; Translational Research. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: Chapter 1. Marine biopolymers for oral delivery of drug -- Chapter 2. Marine polymer based nanocarriers for drug delivery application -- Chapter 3. Alginate: A promising biopolymer in drug delivery system -- Chapter 4. Chitosan Based Nanocomposite as Targeted drug delivery Carrier -- Chapter 5. Marine Biopolymer Based Oral In situ Gel: Drug Delivery Applications -- Chapter 6. Marine biopolymers for transdermal drug delivery -- Chapter 7. Marine polysaccharides for skin drug delivery: hydrogels and microneedles solutions -- Chapter 8. Marine collagen: promising biomaterial in delivery of therapeutics for cancer therapy -- Chapter 9. Chitosan based gel for ocular drug delivery. Chapter 10. Marine based biopolymers for central nervous system drug delivery -- Chapter 11. Marine Biopolymers Based Anticancer Drug Delivery Systems -- Chapter 12. Marine-Derived polysaccharides: prospects for future pharmaceuticals and drug delivery systems.
    Abstract: This book is focused on marine based biomedical carriers for delivery of therapeutics. Marine biomaterials and bio-based carriers show wide applications in pharmaceutical as well as biomedical fields for delivery of small and large molecules. Biomaterial-based composites, scaffolds or matrix systems are promising systems for controlled and prolonged release of drug in target site and control the premature release of drugs or bioactive compounds. This book discusses the targeted delivery of drugs and therapeutic applications. It also describes the use of marine biopolymers in cancer therapy. Different chapters describe the tissue engineering techniques to develop these carriers. The marine biomaterial-based systems are widely used for tissue engineering, and biomedical imaging. This book is meant for industry experts, students and researchers in the area of pharmaceutical sciences, biomedical engineering and material science and pharmacology.
    Type of Medium: Online Resource
    Pages: X, 453 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811647871
    URL: https://doi.org/10.1007/978-981-16-4787-1
    DOI: 10.1007/978-981-16-4787-1
    DDC: 615
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  • 50
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    Online Resource
    Parkinsonism and the Environment (2022)
    Cham :Springer International Publishing :
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    Keywords: Pharmacology. ; Neurosciences. ; Pharmacology. ; Neuroscience.
    Description / Table of Contents: Experimental evidence for pesticide contribution in the pathogenesis of Parkinsonism: an update -- Epidemiological evidence for pesticide involvement in the etiology of Parkinson’s Disease: current state of affairs?” -- Manganese induced Parkinsonism: cellular and molecular mechanisms -- Manganese overexposures in occupational and environmental settings and Parkinsonism: where do we stand -- Aberrant dopamine metabolism as a focal point in the mechanism of environmental contaminant-induced dopaminergic dysfunction -- Emerging contaminants as contributors to Parkinsonism: focus on PhiPs -- Emerging contaminants as contributors to Parkinsonism: focus on PhiPs -- Protein kinase C-delta (PKC-delta): a major molecular target for disparate dopaminergic toxicants -- Environmental contribution to redox dyshomeostasis in Parkinsonism.
    Abstract: “The book is comprised of individual reviews with the common goal of providing up-to-date state of the knowledge information on the role the environment plays in the pathogenesis of parkinsonism. The reviews focus on recent advances in the quest of deciphering the molecular and cellular mechanisms of parkinsonian dysfunction, highlight specific emerging dopaminergic toxicants and an alternative experimental model to study the link between environmental exposures and parkinsonism, and provide an update from epidemiological and experimental points of view related to the pesticide exposures and parkinsonism/Parkinson’s Disease association. Foremost experts in their respective fields are the senior authors on each chapter and the book fills a critical void that now exists as a book of similar nature has not been published in the last 15 years. Researchers and clinicians with an interest in Parkinson's Disease and related disorders, as well as toxicologists, graduate students, and the general public who are interested in the contribution of environmental factors to neurological dysfunction are among the readership for this book.”.
    Type of Medium: Online Resource
    Pages: V, 158 p. 14 illus., 8 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030874513
    Series Statement: Molecular and Integrative Toxicology,
    URL: https://doi.org/10.1007/978-3-030-87451-3
    DOI: 10.1007/978-3-030-87451-3
    DDC: 615
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  • 51
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    Ethnopharmacology and Drug Discovery for COVID-19: Anti-SARS-CoV-2 Agents from Herbal Medicines and Natural Products (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Natural products. ; Nanobiotechnology. ; Bioinformatics. ; Diseases Causes and theories of causation. ; Molecular biology. ; Pharmacology. ; Natural Products. ; Nanobiotechnology. ; Bioinformatics. ; Pathogenesis. ; Molecular Biology.
    Description / Table of Contents: 1. COVID-19: An overview of virology, mutations, pathology, epidemiology, diagnosis, preventions and treatments -- 2. The recent development of therapeutic strategies against COVID-19 -- 3. Plant immunoenhancers: Promising ethnopharmacological candidates for anti-SARS-CoV-2 activity -- 4. Herbal formulations in fighting against the SARS-CoV-2 infection -- 5. Rejuvenation of traditional medicine in the 21st century against SARS-CoV-2 -- 6. Traditional herbal medicines and their active constituents in combating SARS-CoV-2 infection -- 7. Antiviral phytocompounds against animal-to-human transmittable SARS-CoV-2 -- 8. Plants-derived bioactive compounds as potential ACE-2 inhibitors against SARS-CoV-2 infection -- 9. Insights into in silico methods to explore plant bioactive substances in combating SARS-CoV-2 -- 10. Dietary plants, spices and fruits in curbing SARS-CoV-2 virulence -- 11. Therapeutic potential of selected medicinal plants for neurological disorders after the infection of COVID-19 -- 12. Glycyrrhizae Radix et Rhizoma (Gan Cao) for the management of COVID-19 -- 13. COVID-19-induced kidney disease: Ethnopharmacological intervention to ameliorate kidney damage and improve kidney function -- 14. Phytochemicals and nutraceuticals targeting SARS-CoV-2: An in silico analysis -- 15. Therapeutic and prophylactic effects of plant derivatives against SARS-CoV-2 -- 16. Therapeutic potential of essential oils against SARS-CoV-2 infection -- 17. Antiviral properties of South Indian plants against SARS-CoV-2 -- 18. Immune-boosting plants used in Turkish folk medicine and their potential against COVID-19 -- 19. A comparison study of medicinal plants used against SARS-CoV-2 and those recommended against malaria in Africa -- 20. Exploring the potential antiviral properties of Nigella sativa L. against SARS-CoV-2: Mechanisms and prospects -- .
    Abstract: This book presents a complete overview of COVID-19 and provides a series of in-depth analyses of the literature and a comprehensive discussion and perspectives on promising anti-SARS-CoV-2 agents based on the system of ethnopharmacology, which covers Chinese medicine, traditional medicines of India and Africa, Turkish folk medicine, essential oils, and some well-known medicinal plants. In this book, the current status of therapeutic strategies against COVID-19 was summarized and a perspective of potential options for the future was proposed. Based on ethnopharmacology, some well-established traditional herbal formulations and bioactive compounds with anti-virus activity were repurposed for managing COVID-19 and post-illness, including neurological disorders and kidney illness. Using drug discovery tools, promising immune enhancers were explored from phytochemicals against SARS-CoV-2. Nutraceuticals from dietary plants, spices, and fruits with anti-virus and antioxidant activities were recommended to prevent infection or severe illness caused by emerging variants. With the aid of systems pharmacology, researchers have gained insights into possible molecular mechanisms of anti-SARS-CoV-2 activity and have predicted a range of candidate compounds from medicinal plants to combat COVID-19. This book explores the current knowledge of drug discovery and ethnopharmacology for managing coronavirus diseases. The content proved the anti-SARS-CoV-2 activity from natural products and traditional herbal medicines. It contributes to the management of global public health and fits the goal of establishing “Good Health and Well-Being,” which is one of “The Sustainable Development Goals (SDGs) 2030".
    Type of Medium: Online Resource
    Pages: IX, 590 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819936649
    URL: https://doi.org/10.1007/978-981-99-3664-9
    DOI: 10.1007/978-981-99-3664-9
    DDC: 615
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    Novel Drug Targets With Traditional Herbal Medicines : Scientific and Clinical Evidence (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Toxicology. ; Pharmaceutical chemistry. ; Medicinal chemistry. ; Natural products. ; Pharmacology. ; Toxicology. ; Pharmaceutics. ; Medicinal Chemistry. ; Natural Products.
    Description / Table of Contents: Chapter 1: Achillea biebersteinii Afan -- Chapter 2: Aesculus hippocastanum L. -- Chapter 3: Berberis crataegina DC. -- Chapter 4: Calendula officinalis L. -- Chapter 5: Camellia sinensis (L.) Kuntze -- Chapter 6: Capsella bursa-pastoris (L.) Medik. -- Chapter 7: Capsicum annuum L. -- Chapter 8: Cedrus libani A.Rich. -- Chapter 9: Chelidonium majus L. -- Chapter 10: Cichorium intybus L. -- Chapter 11: Cistus laurifolius L. -- Chapter 12: Coriandrum sativum L. -- Chapter 13: Cornus mas L. -- Chapter 14: Curcuma longa L..-Chapter 15: Cydonia oblonga Mill. -- Chapter 16: Cynara scolymus L. -- Chapter 17: Equisetum arvense L. -- Chapter 18: Foeniculum vulgare Mill. -- Chapter 19: Fraxiınus ornus L. -- Chapter 20: Fumaria officinalis L. -- Chapter 21: Helichrysum plicatum DC. -- Chapter 22: Hyoscyamus niger L. -- Chapter 23: Juglans regia L. -- Chapter 24: Laurus nobilis L. -- Chapter 25: Liquidambar orientalis Miller -- Chapter 26: Matricaria chamomilla L. -- Chapter 27: Melissa officinalis L. -- Chapter 28: Momordica charantia L. -- Chapter 29: Nigella sativa L. -- Chapter 30: Olea europaea L. -- Chapter 31: Papaver somniferum L. -- Chapter 32: Rheum ribes L. -- Chapter 33: Rosa canina L. -- Chapter 34: Rosmarinus officinalis L. -- Chapter 35: Silybum marianum L. Gaertn. -- Chapter 36: Urtica dioica L -- Chapter 37: Valeriana officinalis L. -- Chapter 38: Viburnum opulus L.
    Abstract: This book collects information about the most popular ethnomedicinal plants, which are common in Turkey and around the world. It presents the ethnopharmacological records, in vivo and in vitro studies, side effects, chemical compositions and clinical studies of these medicinal plants. Its special focus is on the novel drug targets for disease and their possible mechanisms of action. It covers botanical descriptions the status of the plants, and food or drug interactions including precautions and warnings about the plants and the available market products. It provides an explanation of recorded and known plant administration dosages. Also, the gap between the traditional practice and scientific/clinical evidences in the use of ethnomedicinal plant is acknowledged. It is well known that traditional knowledge of the use of the medicinal plants in therapy is an important resource for the discovery of novel treatment options and drug targets. The main purpose of this book is to draw attention to ethnomedicinal plant species. Data on the therapeutic potentials of these medicinal plants can now be accessed from a single source. It provides an important resource for future research opportunities for harnessing the full potential of these plants.
    Type of Medium: Online Resource
    Pages: XII, 588 p. 119 illus., 43 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031077531
    URL: https://doi.org/10.1007/978-3-031-07753-1
    DOI: 10.1007/978-3-031-07753-1
    DDC: 615
    Language: English
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    Herb-Drug Combinations : A New Complementary Therapeutic Strategy (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Pharmacology. ; Pharmacy. ; Alternative medicine. ; Pharmacovigilance. ; Medicinal chemistry. ; Pharmacology. ; Pharmacy. ; Complementary and Alternative Medicine. ; Drug Safety and Pharmacovigilance. ; Medicinal Chemistry.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. Measuring Herb-drug interaction and Synergy -- Chapter 3. Herb-Herb and Food-drug interactions -- Chapter 4. Pharmacokinetic interactions in synergistic herb-drug combinations -- Chapter 5. Antagonistic Herb-drug interactions -- Chapter 6. Synergistic Herb-drug interactions against bacteria -- Chapter 7. Synergistic herb-drug interactions against tuberculosis -- Chapter 8. Synergistic herb-drug interactions against viral diseases -- Chapter 9. Synergistic herb interactions with cardiovascular drugs -- Chapter 10. Synergistic herb interactions with anticancer drugs -- Chapter 11. Synergistic herb interactions with antidiabetic drugs -- Chapter 12. Synergistic herb-drug interactions against obesity -- Chapter 13. Synergistic Herb-Drug Interactions in Neurological Disorders -- Chapter 14. Synergistic Herb-drug interactions with antifungal and antiparasitic agents -- Chapter 15. Computational methods to study herb-drug interactions -- Chapter 16. Regulations and guidelines involving synergistic plant-drug interactions -- Chapter 17. Clinical trials on synergistic herb-drug interactions -- Chapter 18. QFuture prospects on synergistic herb-drug interactions -- Chapter 19. Conclusion.
    Abstract: Plant extracts or their pure natural constituents have been used traditionally for thousands of years for treating diseases with considerable success in India and other Asian countries. In addition, they have also been used as complements or supplements with conventional medicine. This book discusses the latest research in the application of combination therapy, namely herbs and drugs, in the treatment of a range of communicable and non-communicable diseases to achieve a synergistic effect. This synergy may help in reducing the amount of drug, its toxicity, side effects, and development of resistance as well as improve its efficacy. The book also discusses the pharmacodynamic and pharmacokinetic parameters, experimental tools to determine the impact of combination, computational approaches to identify synergy, statistical analysis of data, and clinical and regulatory issues. The book is useful for researchers in the fields of pharmacology, pharmacy and medicinal chemistry and those working in pharmaceutical and nutraceutical industries. This book could open up new strategies to focus on multiple targets to combat complex diseases unlike the single targeted drugs that are being currently marketed by the pharmaceuticals industries.
    Type of Medium: Online Resource
    Pages: XV, 276 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811951251
    URL: https://doi.org/10.1007/978-981-19-5125-1
    DOI: 10.1007/978-981-19-5125-1
    DDC: 615
    Language: English
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    Online Resource
    Sex and Gender Effects in Pharmacology (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Pharmacology. ; Immunology. ; Neurology . ; Endocrinology. ; Cardiology. ; Pharmacology. ; Immunology. ; Neurology. ; Endocrinology. ; Cardiology.
    Description / Table of Contents: Part 1 Pharmacological Basic Principles -- The impact of sex and gender in medicine and pharmacology -- Sex differences in pharmacokinetics -- Clinical pharmacological considerations in transgender medicine -- Sex and gender differences in the pharmacology of the overactive urinary bladder -- Part 2 Pathologies of the Brain -- Sex differences in the evaluation and treatment of stroke -- Sex differences in pain and its treatment -- Therapeutics For Substance-Using Women: The Need To Elucidate Sex-Specific Targets For Better-Tailored Treatments -- Intersection of sex and depression: pathogenesis, presentation and treatments -- Biological and clinical implications of sex-specific differences in Alzheimer’s disease -- Part 3 Diabetes, metabolic diseases & cardiovascular risk -- Gender Differences In Cardiovascular Health: Hormonal Effects on Cardiovscular Risk And Management. - Sex Differences in Glucose Homeostasis -- Sex-gender-based differences in metabolic diseases -- Hypothalamic pituitary gonadal axis disorders impacting fertility in both sexes and the potential of kisspeptin-based therapies to treat them.
    Abstract: Biological sex and gender have a tremendous impact on the efficacy and safety of pharmacological interventions in virtually every disease state. This book presents a comprehensive and up-to-date overview on how sex-specific information is guiding the diagnosis and treatment of diseases affecting men and women, as well as of disease states that disproportionally affects women. Experts in various fields discuss both preclinical and clinical research that is contributing to a better understanding of the impact of sex in the presentation, etiology, treatment, and disease outcomes. Also discussed are the challenges encountered in implementing this growing body of knowledge into practice, as well as possible avenues to recognize and reduce health disparities between men and women so that therapeutic interventions are tailored and improved.
    Type of Medium: Online Resource
    Pages: VIII, 288 p. 100 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031426483
    Series Statement: Handbook of Experimental Pharmacology, 282
    URL: https://doi.org/10.1007/978-3-031-42648-3
    DOI: 10.1007/978-3-031-42648-3
    DDC: 615
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    Online Resource
    Structural Geological Atlas (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Geology. ; Mineralogy. ; Geology. ; Mineralogy.
    Description / Table of Contents: Barmer basin -- Deccan Traps -- Lesser Himalaya -- Ladakh Himalaya -- Aravalli.
    Abstract: This book presents more than 600 eye-catching structural geological photographs and explanatory descriptions, from different Indian terrains. This book will enable easy identification of deformation features, one of the most important tasks in structural geology at the meso- and micro-scales. The book focuses on ductile and brittle shear sense indicators. This book suits for the undergraduate and graduate geoscience students. The book will be of considerable interest to tectonicians and structural geologists, given the enormous international importance of Indian terrains for exploration and other purposes.
    Type of Medium: Online Resource
    Pages: VII, 623 p. 609 illus., 608 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811398254
    URL: https://doi.org/10.1007/978-981-13-9825-4
    DOI: 10.1007/978-981-13-9825-4
    DDC: 551
    Language: English
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  • 56
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    Glaciers and Ice Sheets in the Climate System : The Karthaus Summer School Lecture Notes (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Geology. ; Climatology. ; Environment. ; Physical geography. ; Geology. ; Climate Sciences. ; Environmental Sciences. ; Physical Geography.
    Description / Table of Contents: Flow of ice -- Thermal structure -- Basal processes -- Tidewater glaciers -- Ice shelves D ocean interaction -- Polar meteorology -- Mass balance -- Numerical methods -- Inverse modeling -- Analytic ice sheet models and climate change -- Firn -- Ice cores -- Remote sensing -- Geophysics -- Geodynamics -- Paleo-ice sheets -- Geomorphology -- Glacier fluctuations -- Tropical glaciers -- Historical glaciology.
    Abstract: Our realisation of how profoundly glaciers and ice sheets respond to climate change and impact sea level and the environment has propelled their study to the forefront of Earth system science. Aspects of this multidisciplinary endeavour now constitute major areas of research. This book is named after the international summer school held annually in the beautiful alpine village of Karthaus, Northern Italy, and consists of twenty chapters based on lectures from the school. They cover theory, methods, and observations, and introduce readers to essential glaciological topics such as ice-flow dynamics, polar meteorology, mass balance, ice-core analysis, paleoclimatology, remote sensing and geophysical methods, glacial isostatic adjustment, modern and past glacial fluctuations, and ice sheet reconstruction. The chapters were written by thirty-four contributing authors who are leading international authorities in their fields. The book can be used as a graduate-level textbook for a university course, and as a valuable reference guide for practising glaciologists and climate scientists.
    Type of Medium: Online Resource
    Pages: XXVII, 530 p. 283 illus., 214 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030425845
    Series Statement: Springer Textbooks in Earth Sciences, Geography and Environment,
    URL: https://doi.org/10.1007/978-3-030-42584-5
    DOI: 10.1007/978-3-030-42584-5
    DDC: 551
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    Sustainable Groundwater Management : A Comparative Analysis of French and Australian Policies and Implications to Other Countries (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Geology. ; Environmental management. ; Power resources. ; Environment. ; Water. ; Hydrology. ; Geology. ; Environmental Management. ; Natural Resource and Energy Economics. ; Environmental Sciences. ; Water.
    Description / Table of Contents: Chapter 1. Sustainable Groundwater Management in France and Australia: Setting Extraction Limits, Allocating Rights and Reallocation -- Chapter 2. Groundwater in France: Resources, Use and Management Issues -- Chapter 3. Groundwater Policy in France: From Private to Collective Management -- Chapter 4. Groundwater Management Planning at the River Basin District Level: Comparative Analysis of the Adour-Garonne and Loire-Bretagne River Basins -- Chapter 5. Lessons from Twenty Years of Local Volumetric Groundwater Management: The case of the Beauce Aquifer, Central France -- Chapter 6. Groundwater in Australia: Occurrence and Management Issues -- Chapter 7. The Evolution of Groundwater Management Policy in the States of Australia -- Chapter 8. Developing a Coordinated Groundwater Management Plan for the Interstate Murray-Darling Basin -- Chapter 9. Information Systems for Sustainable Management of Groundwater Extraction in France and Australia -- Chapter 10. The Challenge of Making Ground-water Visible: A Review of Communication Approaches and Tools in France -- Chapter 11. Conceptual Approaches, Methods and Models used to Assess Abstraction Limits for Unconfined Aquifers in France -- Chapter 12. Setting Sustainable Abstraction Limits in Confined Aquifers: Example from Deep Confined Aquifers in the Bordeaux Region, France -- Chapter 13. A tool to Determine Annual Ground-Water Allocations in the Tarn-et-Garonne Alluvial Aquifer (France) -- Chapter 14. Conceptual Approaches, Methods and Models used to Assess Extraction Limits in Australia: From Sustainable to Acceptable Yield -- Chapter 15. Case Study: An Integrated Approach to Determining Sustainable Abstraction Limits in Perth’s North West Urban Growth Corridor -- Chapter 16. Using Resource Condition Limits to Define Groundwater Management Objectives in the Barossa Valley, South Australia -- Chapter 17. Reducing Entitlements when Groundwater has been Over-allocated: Policy Issues and Options -- Chapter 18. Developing Substitution Resources as Compensation for Reduced Groundwater Entitlements: The Case of the Poitou Marshes (France) -- Chapter 19. New Approaches for Allocation Reductions and Groundwater Salinity Management in South Australia -- Chpater 20. Reducing Groundwater Entitlements in the Lower Murrumbidgee Groundwater Management Area -- Chapter 21. Development of Groundwater Markets in Australia: Insights from Victoria in the Murray Darling Basin -- Chapter 22. Groundwater Regulation, Compliance and Enforcement: Insights on Regulators, Regulated Actors and Frameworks in New South Wales, Australia -- Chapter 23. Compliance and Enforcement: the Achilles Heel of French Water Policy -- Chapter 24. The Role of Sectoral Policies to Restore Groundwater Balance: The Impact of Agricultural Policies on Irrigation Water Demand in France -- Chapter 25. Groundwater Management Lessons from Chile -- Chapter 26. California’s 2014 Sustainable Groundwater Management Act – From the Back Seat to the Driver Seat in the (Inter)National Groundwater Sustainability Movement -- Chapter 27. Changing from Unrestricted access to Sustainable Abstraction Management Regimes: Lessons Learnt from France and Australia. .
    Abstract: This book describes and analyses the diversity of possible approaches and policy pathways to implement sustainable groundwater development, based on a comparative analysis of numerous quantitative management case studies from France and Australia. This unique book brings together water professionals and academics involved for several decades in groundwater policy making, planning or operational management to reflect on their experience with developing and implementing groundwater management policy. The data and analysis presented accordingly makes a significant contribution to the empirical water management literature by providing novel, real world insights unpublished elsewhere. The originality of the contributions also lies in the different disciplinary perspectives (hydrogeology, economics, planning and social sciences in particular) adopted in many chapters. The book offers a unique comparative analysis of France, Australia and experiences in countries such as Chile and the US to identify similarities, but also fundamental differences, which are analysed and presented as alternative policy options – these differences being mainly related to the role of the state, the community and market mechanisms in groundwater management.
    Type of Medium: Online Resource
    Pages: XVII, 562 p. 149 illus., 143 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030327668
    Series Statement: Global Issues in Water Policy, 24
    URL: https://doi.org/10.1007/978-3-030-32766-8
    DOI: 10.1007/978-3-030-32766-8
    DDC: 551
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    Mineral Micro-Geochemistry Constraints on Petrogenesis and Genesis of Gold Deposit (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Geology. ; Mineralogy. ; Geochemistry. ; Geology. ; Mineralogy. ; Geochemistry.
    Description / Table of Contents: Introduction -- Geological setting -- Micro-geochemistry of clinopyroxene of the mafic dykes in the Jiaodong peninsula: Implications for petrogenesis and geodynamic -- Micro-geochemistry of pyrite and gold mineral in Jiaodong gold deposits: Implications for genesis of gold deposit.
    Abstract: Minerals respond texturally and compositionally to changing magmatic environments and preserve a wealth of information regarding magmatic processes and compositions in their crystal-growth stratigraphy. This book reports the detailed petrography and in-situ geochemistry of the clinopyroxene phenocrysts of the mafic dykes in the Jiaodong Peninsula, southeastern North China Craton, including in-situ determinations of major elements, trace elements, Sr isotopic compositions, and H2O contents with further constraints on the petrogenesis and geodynamics of the mafic dykes. Systematic analyses of mineralogical, major, and trace elements, Sr–Nd isotopes, and in-situ S isotopes on the pyrite of the main gold-bearing mineral assemblages and visible gold were conducted, aiming to explore the source of ore-forming materials and the process of Au element migration and deposition. The geodynamic setting of mineralization in the studied region is also summarized.
    Type of Medium: Online Resource
    Pages: VIII, 203 p. 63 illus., 59 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811610226
    URL: https://doi.org/10.1007/978-981-16-1022-6
    DOI: 10.1007/978-981-16-1022-6
    DDC: 551
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    Geology of the Cayman Islands : Evolution of Complex Carbonate Successions on Isolated Oceanic Islands (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Geology. ; Water. ; Hydrology. ; Sedimentology. ; Earth sciences. ; Geography. ; Geology. ; Water. ; Sedimentology. ; Earth Sciences. ; Geography.
    Description / Table of Contents: Introduction -- Tectonic Setting of Cayman Islands -- Stratigraphic framework -- The Bluff Group -- The Ironshore Formation -- Modern marine sediments of the Cayman Islands -- Dolomitization of the Bluff Group -- Karst and caves -- Phosphates, terra rossa and mangrove peat -- Modern Hydrology -- Summary Information Database.
    Abstract: Grand Cayman, Little Cayman, and Cayman Brac are, in reality, the summits of independent fault blocks that rise from the depths of the Caribbean Sea. This book traces the geological evolution of these islands over the last 30 to 35 million years. The balance between deposition of carbonate sediments and karst development of the exposed land was dictated by the interaction between ever-changing sea levels and vertical tectonic movement of the fault blocks. Today, drinking water needed for the ever-increasing populations of the islands is supplied largely by desalinization plants that are located in accord with a detailed knowledge of the bedrock. This book is based on an extensive data base that has been assembled over the last 40 years of field work and laboratory analyses. Noteworthy aspects of this database include: Approximately 60 visits to the islands over last 40 years – sampling and documentation of virtually every accessible outcrop on the islands (including some that no longer exist). Most samples have been fully documented petrographically and geochemically. Data from 120 wells that have been drilled to depths up to 245 m (most less than 125 m). Wells have been cored and/or chip sampled. Full documentation of drilling histories, XRD analyses of samples, extensive geochemical analyses for major and minor elements, stable isotopes, 87Sr/86Sr ratios, and Rare Earth Elements from numerous samples. Mapping and sampling of modern sediments, including sediment cores, from most of the lagoons around Grand Cayman. Extensive thin section petrography, scanning electron microscope, and electron microprobe analyses of the dolostones and limestones that form the bedrock of the islands. Samples and data collected from numerous caves on Grand Cayman and Cayman Brac have been used to track their developmental history. Detailed analyses of phosphates collected from Little Cayman. Detailed analyses of terra rossa collected from each of the islands.
    Type of Medium: Online Resource
    Pages: XIII, 291 p. 247 illus., 232 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031082306
    URL: https://doi.org/10.1007/978-3-031-08230-6
    DOI: 10.1007/978-3-031-08230-6
    DDC: 551
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    Seasonal Flood Forecasts and Warning Response Opportunities : ENSO Applications in Bangladesh (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Natural disasters. ; Environment. ; Physical geography. ; Environmental management. ; Natural Hazards. ; Environmental Sciences. ; Earth System Sciences. ; Environmental Management.
    Description / Table of Contents: TABLE OF CONTENTS Preface: Why ENSO-based seasonal forecasts are important in Bangladesh Acknowledgements -- About the author -- Chapter 1: Introduction—Seasonal Flood Potential in Bangladesh -- Chapter 2: Basin-wide Hydro-Meteorological Variability and Opportunity for Seasonal -- Forecasts in Bangladesh -- Chapter 3: History of Flood Forecasts and Early Warning in Bangladesh -- Chapter 4: Overview of Weather, ENSO, and Climate Scale -- Chapter 5: The El Niño-Southern Oscillation (ENSO) and Seasonal Flooding in Bangladesh -- Chapter 6: Seasonal Flood Potential in Bangladesh -- Chapter 7: Overview of Eastern, Mixed, and Central Pacific El Niño -- Chapter 8: Seasonal Sea Level Information and Flood Forecast Potential in Bangladesh -- Chapter 9: Consensus Seasonal Flood Forecasts and Warning Response in Bangladesh -- Chapter 10: ENSO Impacts, Applications, and Conclusions.
    Abstract: This book explores the feasibility of using El Niño-Southern Oscillation (ENSO)-based forecasts and early warning systems to prevent losses from floods and droughts in Bangladesh. Despite advances in short-range flood forecasting and information dissemination systems in Bangladesh, the present system is less than satisfactory. This is due to short lead-time products, outdated dissemination networks, and lack of direct feedback from the end-user. One viable solution is to produce long-lead seasonal forecasts—the demand for which is significantly increasing in Bangladesh— and disseminate these products through appropriate channels. As observed in other regions, the success of seasonal forecasts, in contrast to short-term forecasts, depends on consensus among the participating institutions. Therefore, the primary objective of the book is to revisit and modify the framework of an ideal warning response system for issuance of consensus seasonal flood forecasts in Bangladesh. The book discusses issues related to the 5-stage Flood Forecasts, Warning, and Response System (FFWRS) and emphasizes the role of the seasonal ‘Climate Outlook Forum (COF)’ in Bangladesh. The book also identifies ways to improve forecasting and early warning systems by utilizing ENSO-based climate data and models, and discusses a comprehensive and participatory approach to seasonal flood hazard management in Bangladesh. Several successful case examples of ENSO-based seasonal forecasts and early warning systems from other ENSO-sensitive regions have been documented. The primary audience includes academics and students, government policymakers, engineers, and business leaders.
    Type of Medium: Online Resource
    Pages: XXX, 201 p. 84 illus., 56 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031178252
    Series Statement: Disaster Risk Reduction, Methods, Approaches and Practices,
    URL: https://doi.org/10.1007/978-3-031-17825-2
    DOI: 10.1007/978-3-031-17825-2
    DDC: 551
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    Marine Oil and Gas Exploration in China (2020)
    Berlin, Heidelberg :Springer Berlin Heidelberg :
    Details
    Keywords: Geology. ; Sedimentology. ; Oceanography. ; Cogeneration of electric power and heat. ; Fossil fuels. ; Geology. ; Sedimentology. ; Ocean Sciences. ; Fossil Fuel.
    Description / Table of Contents: Regional tectonic setting and prototype basin evolution -- Characteristics and evolution of Lithofacies Paleogeography -- Major source rocks and distribution -- Reservoir type and origin -- Regional cap rock and hydrocarbon preservation -- Reservoir type and spatial distribution.
    Abstract: This book systematically introduces the petroleum geological characteristics and exploration theory of marine strata in China. On the basis of four major basins, 14 typical cases have been studied in which 13 cases are from conventional oil and gas fields and 1 case is from shale gas field, along with their hydrocarbon generation, migration, accumulation, and distribution characteristics. The book provides a reference for geologists around the globe to understand the exploration history, methods and advances in marine strata oil and gas exploration in China.
    Type of Medium: Online Resource
    Pages: XXII, 570 p. 322 illus., 295 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783662611470
    URL: https://doi.org/10.1007/978-3-662-61147-0
    DOI: 10.1007/978-3-662-61147-0
    DDC: 551
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    Suriname Revisited: Economic Potential of its Mineral Resources (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Geology. ; Mineralogy. ; Power resources. ; Geology. ; Mineralogy. ; Natural Resource and Energy Economics.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. Geology of Suriname -- Chapter 3. A Brief History of Exploration Work -- Chapter 4. Modeling Potential: Minimal Economic Resource Parameters -- Chapter 5. Gold -- Chapter 6. Bauxite -- Chapter 7. Base metals -- Chapter 8. Other Metallic Minerals -- Chapter 9. Critical Raw Materials -- Chapter 10. Other Minerals -- Chapter 11. Looking ahead.
    Abstract: This book summarizes the exploration history and provides a framework for assessing the economic potential of the country’s minerals by defining minimal deposit parameters for the various commodities present. Suriname was explored extensively for mineral occurrences in the course of the previous century, indicating the presence of a range of commodities. The country mined and processed bauxite for a century (until 2016), and has an even longer history of small-scale alluvial gold mining; it is currently home to two major gold producers. However, exploration activities have been limited during the past 4 decades as most parts of Suriname’s interior are difficult to access, making geological fieldwork both difficult and expensive. Further, the markets and prices have changed in the interim, which calls for a fresh look at the historic data. .
    Type of Medium: Online Resource
    Pages: XV, 90 p. 33 illus., 29 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030402686
    Series Statement: SpringerBriefs in Earth Sciences,
    URL: https://doi.org/10.1007/978-3-030-40268-6
    DOI: 10.1007/978-3-030-40268-6
    DDC: 551
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    Slate as Dimension Stone : Origin, Standards, Properties, Mining and Deposits (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Geology. ; Mineralogy. ; Conservation biology. ; Ecology . ; Geotechnical engineering. ; Geology. ; Mineralogy. ; Conservation Biology. ; Geotechnical Engineering and Applied Earth Sciences.
    Description / Table of Contents: 1.Slate in architecture -- 2.The origin of slate -- 3.Methodology and standards -- 4.Properties of slate -- 5.Weathering of slate -- 6.Mining of slate and production -- 7.Slate deposits.
    Abstract: This book offers a comprehensive review devoted exclusively to slate as dimension stone. Beginning with a description of the slate as dimension stone, the book describes the origin of slate and related geological phenomena. It thoroughly explains key data acquisition methods and techniques, which are accompanied by extensive data. In turn, slate standards are introduced and compared with regard to their importance for product quality. The book covers in detail the specific petrographical, fabric, strength, physical properties and weathering behaviour of slates. The chapter on mining and production provides an overview of the different forms of exploitation and related geotechnical aspects, together with production and workflow design, from the beginning to the final product. The second part comprises a thorough description of worldwide slate deposits and their geology, properties and appearance as well as a brief introduction of the history. Given its scope and accessible format, the book represents an essential guide for scientists, engineers, and professionals in geology, conservation science, architecture, and mining, as well as readers who are active in the slate industry.
    Type of Medium: Online Resource
    Pages: XI, 492 p. 305 illus., 283 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030356675
    Series Statement: Springer Mineralogy,
    URL: https://doi.org/10.1007/978-3-030-35667-5
    DOI: 10.1007/978-3-030-35667-5
    DDC: 551
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    The Geology of Kuwait (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Geology. ; Sedimentology. ; Paleontology . ; Geophysics. ; Geology. ; Sedimentology. ; Paleontology. ; Geophysics.
    Description / Table of Contents: Chapter 1. Surface Geology of Kuwait -- Chapter 2. Subsurface stratigraphy of Kuwait -- Chapter 3. Sand dunes in Kuwait, morphometric and chemical characteristics -- Chapter 4. Marine Geology of Kuwait -- Chapter 5. Structures and Tectonics of Kuwait.
    Abstract: This open access book contains a set of chapters covering all aspects of geosciences related to Kuwait and adjactent regions, including Iran, Saudi Arabia and the Arab Gulf states. It covers basic information about the geology including a wide range of geoscientific disciplines such as marine geology, structural geology, hydrogeology and geophysics related to the region. This book is aimed at researchers and students, as well as professionals in the field of hazard mitigation and petroleum exploration.
    Type of Medium: Online Resource
    Pages: XII, 242 p. 211 illus., 177 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031167270
    Series Statement: Regional Geology Reviews,
    URL: https://doi.org/10.1007/978-3-031-16727-0
    DOI: 10.1007/978-3-031-16727-0
    DDC: 551
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    Introduction to GNSS Geodesy : Foundations of Precise Positioning Using Global Navigation Satellite Systems (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Geology. ; Measurement. ; Measuring instruments. ; Geographic information systems. ; Geotechnical engineering. ; Geology. ; Measurement Science and Instrumentation. ; Geographical Information System. ; Geotechnical Engineering and Applied Earth Sciences.
    Description / Table of Contents: Chapter 1-Introduction -- Chapter 2-Reference systems in GNSS geodesy -- Chapter 3-Estimating geodetic parameters from GNSS -- Chapter 4-GNSS satellite tracking and observation models -- Chapter 5-Geodetic CORS and tracking networks -- Chapter 6-Satellite orbit determination -- Chapter 7-GNSS data processing and biases -- Chapter 8-GNSS software and online tools -- Chapter 9-GNSS geodetic solution exchange formats -- Chapter 10-GNSS time series combinations and data products -- Chapter 11-Geospatial applications of GNSS geodesy -- Chapter 12-Scientific applications of GNSS geodesy.
    Abstract: Introduction to GNSS Geodesy is a concise reference for beginners and experts in GNSS-based satellite geodesy. It covers all of the important concepts in almost a third of the space of the other GNSS books. Th e book begins with a case study in Augmented Reality to set the stage for what is to come and then moves on to the key elements of GNSS geodesy that make accurate and precise geopositioning possible. For example, it is important to understand the geodetic reference systems and the associated GNSS data processing strategies that enable both accurate and high-precision geopositioning. Chapter 2 gives an overview of GNSS constellations and signals, highlighting important characteristics. Chapter 3 then introduces reference systems in geodesy, covering such topics as time systems, geodetic datums, coordinate systems, coordinate conversions and transformations, and International Terrestrial Reference Frame. Th is lays the framework for the rest of the book. Chapters 4 and 5 dig deep into mathematical formulation of GNSS parameter estimation and observation models. All the concepts are presented clearly and concisely, with diagrams to assist reader comprehension. Chapter 6 describes Continuously Operating Reference Station (CORS) networks and their role in geodesy and definition of reference frames. Various global and regional CORS networks are presented in this section. Th e chapter also covers GNSS data and common formats such as RINEX and RTCM. Chapter 7 introduces the whole cycle of GNSS data processing, including preprocessing, ambiguity fixing, and solution reprocessing methods as commonly used in both epoch solutions and time series data. Th e book concludes with appendices on orbit modelling, GNSS linear combinations, application examples, and an example linear model.
    Type of Medium: Online Resource
    Pages: XV, 166 p. 43 illus., 38 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030918217
    URL: https://doi.org/10.1007/978-3-030-91821-7
    DOI: 10.1007/978-3-030-91821-7
    DDC: 551
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    Structural Geology and Tectonics Field Guidebook—Volume 2 (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Geology. ; Sedimentology. ; Paleontology . ; Petrology. ; Geology. ; Sedimentology. ; Paleontology. ; Petrology.
    Description / Table of Contents: Chapter 1 - Field guide for a complete cross-section of the Central Andes along main roads (Carla Cristine Porcher, Márcia Elisa Boscato Gomes, Amós Martini, Giuseppe Betino De Toni, João Pacífico Machado) -- Chapter 2 – Structures associated with the dynamics of granitic rock emplacement (NW Portugal) (Jorge Pamplona, Benedito C. Rodrigues, Mark Peternell, Alex Lorenz, Alex Schimdt, Melissa Mengert, Thomas Altmeyer, Jonas Köpping) -- Chapter 3 - Tectonically significant fault zones in Central Europe (Germany, Czech Republic and Poland) and their surface and subsurface outcrops: Franconian Line, Hronov-Porici Fault, Sudetic Marginal Fault and Lusatian Fault (Lucie Novakova) -- Chapter 4 - Geological field observations along the Pandoh Syncline:the Mandi-Kataula-Bajura section of Himachal Pradesh, NW-India (Paramjeet Singh, Pratap Chandra Sethy, Hrithik Rastogi, M. Rajanikanta Singh, A. Krishnakanta Singh, Satyajit Singh Thakur, Saurabh Singhal) -- Chapter 5 - The rock outcrops at Raghunathdi, SE of Ghatsila (Jharkhand, India): A spectacular preservation of polyphase folding (Srinanda Ganguly, Arpita Samanta, Abhik Kundu) -- Chapter 6 - Spectacular soft-sediment deformation structures in sedimentary rock outcrops of Damodar Valley Basin, West Bengal, India: A field guide (Arpita Samanta, Abhik Kundu) -- Chapter 7 - Structural geological field guide: Bhuj area (Gujarat, India) (Nidhi Lohani, Soumyajit Mukherjee, Seema Singh, Aashu Pawar, Mohamedharoon Shaikh) -- Chapter 8 - Structural and sedimentary field studies in Angul District, Odisha, India (Subhajit Sinha, Ananya Ghosh, Somnath Mishra) -- Chapter 9 - New Structural geological input from the Barmer Basin, Rajasthan (India) (Mohit Kumar Puniya, Ashish Kumar Kaushik, Soumyajit Mukherjee, Swagato Dasgupta, Nihar Ranjan Kar, Mery Biswas, Ratna Choudhary) -- Chapter 10 - Structural geology and stability issue of the Giral lignite mine, Rajasthan, India (Mohit Kumar Puniya, Ashish Kumar Kaushik, Soumyajit Mukherjee, Nihar Ranjan Kar, Mery Biswas, Ratna Choudhary) -- Chapter 11 - Relationship between deformation structures and rock mass rating: A case study of underground power house, Andhra Pradesh- India (Mohit Kumar Puniya, Sohan Kumar, Ashish Kumar Kaushik, Nikhil Puniya) -- Chapter 12 - Macrostructures mimic Meso-structures (Harsh Bhu, Ritesh Purohit, Riya Dutta) -- Chapter 13 - Review on Role of multi-constellation Global Navigation Satellite System-Reflectometry (GNSS-R) for real-time sea-level measurements (Kutubuddin Ansari) -- Chapter 14 - Architecture and structures of Kiradu temple (Barmer region, Rajasthan, India) (Paramita Haldar,, Mohit Kumar Puniya, Mery Biswas, Soumyajit Mukherjee, Nihar Ranjan Kar, Ratna Choudhary).
    Abstract: This book is the second volume of an edited work aiming to help novice geologists to explore terrains independently. Geoscience fieldwork with focus on structural geology and tectonics has become more important in the last few years from both academic and industrial perspectives. This book also works as a resource material for batches of students or geological survey professionals undergoing training as parts of their course curriculum/training. Industry persons, on the other hand, can get a first-hand idea about what to expect in the field, in case no academic persons are available with the team. This book focuses on structural geology and tectonics and compiles terrains from several regions of the globe. This book also includes field guide chapters for primary sedimentary structures.
    Type of Medium: Online Resource
    Pages: XVI, 418 p. 323 illus., 304 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031195761
    Series Statement: Springer Geology Field Guides, FieldGuides,
    URL: https://doi.org/10.1007/978-3-031-19576-1
    DOI: 10.1007/978-3-031-19576-1
    DDC: 551
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    The Tectonics and Metallogenesis of Asia (2020)
    Singapore :Springer Nature Singapore :
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    Keywords: Geology. ; Geophysics. ; Mineralogy. ; Geology. ; Geophysics. ; Mineralogy.
    Description / Table of Contents: Introduction -- Tectonic Domains and Tectonic Units in Asian Continent -- The Tectonic Evolution of Asian Continental Lithosphere -- Tectono-Metallogenesis in Asian Continent.
    Abstract: The purpose of this book is to provide a review of tectonic outlines of the Asian continent, metallogenesis rules of 242 large deposits or fields in 67 tectonic units of 6 tectonic domains in the Asia, and guidelines for the mining companies to effectively prospect the large deposits in the Asia in future. The main contents include the tectonic evolution of every tectonic unit in Asia at different geological periods, the mechanism of growth and intraplate deformation of the Asian continental lithosphere, the lithospheric types of the Asian continent, and relationship between tectonic evolution and mineralization process in the Asian continent. .
    Type of Medium: Online Resource
    Pages: XI, 319 p. 201 illus., 190 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811530326
    URL: https://doi.org/10.1007/978-981-15-3032-6
    DOI: 10.1007/978-981-15-3032-6
    DDC: 551
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    Water Resources of Pakistan : Issues and Impacts (2021)
    Cham :Springer International Publishing :
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    Keywords: Geology. ; Water. ; Hydrology. ; Geology. ; Water.
    Description / Table of Contents: Chapter 1 Pakistan’s Water Resources: Overview and Challenges -- Chapter 2 Pakistan’s Water Resources: From Retrospect to Prospect -- Chapter 3 Pakistan’s Transboundary Water Challenge -- Chapter 4 Water Security in Pakistan: Availability, Accessibility and Utilisation -- Chapter 5 Climate Change in the Mountains of Pakistan and its Water Availability Implications -- Chapter 6 Pakistan’s Water Resources in the Era of Climate Change -- Chapter 7 Unlocking Economic Growth Under a Changing Climate: Agricultural Water Reforms in Pakistan -- Chapter 8 Sustainability Analysis of Irrigation Water Management in Punjab -- Chapter 9 Examining Irrigated Agriculture in Pakistan with a Water-Energy-Food Nexus Approach -- Chapter 10 Groundwater Crisis: a Crisis of Governance? -- Chapter 11 Spatial Variability of Groundwater Storage in Pakistan -- Chapter 12 Impacts of Water Quality on Human Health in Pakistan -- Chapter 13 Improving Water Management in Pakistan using Social-Ecological Systems Research -- Chapter 14 A Roadmap for a Comprehensive Water Resources Forecast System for Pakistan -- Chapter 15 Ways Forward to Improve Water Security in Pakistan.
    Abstract: This book presents the first comprehensive assessment of water resources in Pakistan including surface water resources and groundwater resources. It gives a detailed overview of issues and challenges related to water which have not been adequately addressed e.g. water resource vulnerability to climate change, groundwater depletion and contamination, and water governance etc. It includes a collection and compilation of unpublished and scattered data from the archives and repositories of various national institutions and organization. Given the literature dearth, this book will not only be a comprehensive assessment of water resources in Pakistan but can also can as outstanding textbook on water resource management in Pakistan. It will attract a great range of readership including water specialists, researchers, undergraduate and post graduate students and policy makers from Pakistan as well as from overseas.
    Type of Medium: Online Resource
    Pages: XVI, 318 p. 72 illus., 68 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030656799
    Series Statement: World Water Resources, 9
    URL: https://doi.org/10.1007/978-3-030-65679-9
    DOI: 10.1007/978-3-030-65679-9
    DDC: 551
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  • 69
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    Groundwater in Egypt’s Deserts (2021)
    Cham :Springer International Publishing :
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    Keywords: Geology. ; Sustainability. ; Energy policy. ; Energy and state. ; Geophysics. ; Geochemistry. ; Geology. ; Sustainability. ; Energy Policy, Economics and Management. ; Geophysics. ; Geochemistry.
    Description / Table of Contents: Overview of the Egyptian Deserts' Ground Water Resources and Their Qualities -- Fault zone hydrogeology and structural control on groundwater flow in the Egyptian aquifers -- Hydrogeology and Waterlogging problem in Egypt's Deserts, Case Study: Abu Meina Archaeological site , Burg Al-Arab -- Conceptual Models for Groundwater Management in Egypt's Deserts -- Characterizing ecosystem services to human well-being in groundwater dependent desert environments.
    Abstract: This book brings together contributions from groundwater researchers and scientists on underground water resources in Egypt's deserts. The aquifers' quantity and quality are evaluated in many regions of the Egyptian deserts using established methods that can be effectively employed to investigate the potential for sustainable development in Egypt and similarly arid countries. The water resources in Egypt's deserts are subject to deterioration, mainly by land salinization and water deficiency. This book presents the best management practices, water quantity and quality, and optimal and sustainable usage of available groundwater. The book offers a unique guide for all readers interested in groundwater, modeling, and assessment for sustainable development in Egypt and countries with similar weather and water conditions. .
    Type of Medium: Online Resource
    Pages: X, 442 p. 178 illus., 162 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030776220
    Series Statement: Springer Water,
    URL: https://doi.org/10.1007/978-3-030-77622-0
    DOI: 10.1007/978-3-030-77622-0
    DDC: 551
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    Heat-Mass Transfer and Geodynamics of the Lithosphere (2021)
    Cham :Springer International Publishing :
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    Keywords: Geology. ; Thermodynamics. ; Heat engineering. ; Heat transfer. ; Mass transfer. ; Natural disasters. ; Geotechnical engineering. ; Geology. ; Engineering Thermodynamics, Heat and Mass Transfer. ; Natural Hazards. ; Geotechnical Engineering and Applied Earth Sciences.
    Description / Table of Contents: Preface -- The processes of heat and mass transfer in the Earth's mantle -- Thermo-gravity model for sedimentary basins -- Prospects for identifying and applied use of hydro and petrothermal energy sources in geodynamically active structures of the eastern segment of the Central Caucasus -- Models of geothermal areas: new insights from electromagnetic geothermometry -- Explosive processes in permafrost areas - new type of geocryological hazard -- Borehole temperature measurements under free thermal convection -- Geothermal regime of groundwater in Moscow under anthropogenic impact -- Geothermy of the continental margins of Eastern Russia -- Geothermal evidence of cyclic back-arc spreading in the marginal seas of the North-West Pacific -- Heat flow asymmetry on the mid-oceanic ridges of northern and southern earth hemispheres -- The correlation between Earth heat flow and oil and gas potential – fundamental pattern of Western Siberia -- Influence of hydrodynamic conditions on the mass transfer of pollutants in the areas of liquidated mines -- Factor modeling of mass transfer of pollutants in the areas of hydrogeological windows -- Hydraulic fracture problem for poroelastic medium with double porosity -- Incompletely coupled equations of hydraulic fracturing in poroelastic medium -- Geomechanical model for large scale hydraulic fracture dynamics -- Thermodynamic properties of geothermal fluids from South Russiai Kayakent and Kizlyar hot sources -- Thermodynamic properties of geothermal fluids from South Russia: Izberbash and Thernair hot sources -- ROSA Database and GIS Project: accumulation of the world largest oil and gas deposits in geological history -- Lithosphere of the West Transbaikalian sector of the Central Asian fold belt according to electromagnetic studies -- Caucasian-Arabian segment of Alpine-Himalayan convergence: an example of continental collision above mantle plume -- Geothermics and seismicity of the Caucasus region and the inverse problem of geodynamics -- Geothermics and geodynamics of the back-arc basins of the Alpine and Pacific belts -- Structure and dynamics of the lithosphere for the Eurasia-Pacific transition zone -- Recognition of Strong Earthquake–Prone Areas with a Single Learning Class Caucasus, М ≥ -- Evaluation of the influence of soils resonant properties during seismic microzoning work -- Seismotectonic model of the western margin of the South American Plate -- Permeability of the Continental Crust –Possible High Values from Laboratory Measurements and Seismological Data -- Endogenous and exogenous manifestations of geodynamic activity in the Central Caucasus.
    Abstract: This volume is devoted to investigation of all aspects of heat-mass transfer processes at different scales and from various origins, as well as the formation and evolution of geological structures. These phenomena are linked to geophysical properties of rocks, geothermal resources, geothermics, fluid dynamics, stress-state of the lithosphere, deep geodynamics, plate tectonics, and seismicity, among others. The book consists of two main parts. The first concerns heat-mass transfer associated with natural and technogenic processes in the upper lithosphere. The second deals with geodynamics and seismicity. The collection of over 25 chapter from leading investigators in Russia is thus an important contribution to research on the lithosphere in connection with formation and evolution of geological structures; heat and mass transfer processes in the lithosphere and their connection with deep Earth geodynamics. Collects a range of research methodologies including application of modelling, seismic tomography, geological field works, geological-geophysical methods, and in situ measurements through instrumentation; Explains how a wide range of geological and geophysical phenomena arising in the Earth’s lithosphere can be investigated under the umbrella of a common approach to heat-mass transfer processes; Includes the latest research by more than 60 leading scientists from Russia.
    Type of Medium: Online Resource
    Pages: X, 549 p. 205 illus., 149 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030635718
    Series Statement: Innovation and Discovery in Russian Science and Engineering,
    URL: https://doi.org/10.1007/978-3-030-63571-8
    DOI: 10.1007/978-3-030-63571-8
    DDC: 551
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    Ecological Tourism in the Republic of Kazakhstan (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Geology. ; Cultural property. ; Archaeology. ; Conservation biology. ; Ecology . ; Geology. ; Heritage Management. ; Conservation Biology.
    Description / Table of Contents: 1. Scientific and Methodological Basis of the Ecological Tourism Development -- 2. The Natural and Recreational Potential of Kazakhstan for the Ecological Tourism Development -- 3. Social and Economic Tourism Potential of Kazakhstan -- 4. Potential Geoparks of Kazakhstan -- 5. Evaluation of Tourist-Resource Potential On Ecological Tourism At Scale Of Kazakhstan Regions -- 6. Current State and Prospects for The Ecological Tourism Development of Kazakhstan -- 7. Conclusion -- 8. References.
    Abstract: This book analyses the theoretical and methodological foundations of ecotourism and geotourism and examines the essence, content, factors, and models of ecotourism development. The authors conducted research to assess the tourist and recreational potential of ecotourism in Kazakhstan. The study analyses the current state and describes the problems of the long-term development of ecotourism. Besides, the authors also show the role of specially protected natural areas in ecotourism development, including a list of organizations that can create tourist products in the environmental direction. This book also defines the primary conditions necessary for ecotourism in protected natural and rural areas. The resulting cartographic material visualizes the geospatial potential of the regions of Kazakhstan, aiming a more targeted expenditure of financial resources allocated to tourism development. Thus, the presented book is relevant from a practical perspective to scientists and researchers and is of value to business structures and stakeholders.
    Type of Medium: Online Resource
    Pages: VIII, 281 p. 113 illus., 108 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030774622
    URL: https://doi.org/10.1007/978-3-030-77462-2
    DOI: 10.1007/978-3-030-77462-2
    DDC: 551
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    Disaster Risk Communication : A Challenge from a Social Psychological Perspective (2020)
    Singapore :Springer Nature Singapore :
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    Keywords: Natural disasters. ; Environmental sciences Social aspects. ; Climatology. ; Computer simulation. ; Natural Hazards. ; Environmental Social Sciences. ; Climate Sciences. ; Computer Modelling.
    Description / Table of Contents: Pitfall of Disaster Information: From the Perspective of Double-bind Theory -- Single-person Drill for Tsunami Evacuation and Disaster Education -- Using Computer Simulation for Effective Tsunami Risk Communication -- Gaming Approach to Disaster Risk Communication: Development and application of "Crossroad Game" -- Local Weather Information: Collaboration between Weather Forecasters and Information Users -- Disaster Education based on Legitimate Peripheral Participation Theory: A New Model of Disaster Science Communication -- Do Developed Countries Learn DRR from Developing Countries? -- Communicating Warnings in an Immanent Time Frame: Earthquake Early Warning and Short-Term Forecasting in Japan and the US.
    Abstract: This book provides a unique blend of integrated disaster risk communication research conducted by authors with diverse backgrounds, including social psychology, sociology, civil engineering, informatics, and meteorology. It reports on the latest advances in collaborative and participatory action research on community-based disaster management from the frontline in Japan, Nepal, China and the USA. In addition, it employs and integrate a broad range of methodologies, including mathematical analyses, computer simulations, questionnaire surveys, gaming approaches, and participatory observation. Each chapter deals with disaster risk communication initiatives to address various hazards, such as earthquakes, tsunamis, floods and landslides, which are uniquely integrated from a social psychological perspective.
    Type of Medium: Online Resource
    Pages: XXXV, 153 p. 35 illus., 21 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811323188
    Series Statement: Integrated Disaster Risk Management,
    URL: https://doi.org/10.1007/978-981-13-2318-8
    DOI: 10.1007/978-981-13-2318-8
    DDC: 551
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    Geodynamics of the Indian Plate : Evolutionary Perspectives (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Geology. ; Geomorphology. ; Physical geography. ; Geochemistry. ; Geography. ; Geology. ; Geomorphology. ; Earth System Sciences. ; Geochemistry. ; Regional Geography.
    Description / Table of Contents: Chapter1. Introduction -- Chapter2. Evolving Early Earth: Insights from Peninsular India -- Chapter3. Tracking India within Precambrian supercontinent cycles -- Chapter4. Proterozoic Sedimentary basins of India -- Chapter5. Oxygenation of early atmosphere and potential stratigraphic records from India -- Chapter6. Early life from the Proterozoic sedimentary basins of India -- Chapter7. Geodynamics of Gondwanaland -- Chapter8. Cretaceous Volcanism in Peninsular India: Rajmahal_Sylhet, Deccan Traps -- Chapter9. Phanerozoic Mass Extinctions and Indian Stratigraphic Records -- Chapter10. Geological Evolution of the Himalayan Mountains -- Chapter11. Cenozoic Himalayan foreland basin: an overview and regional perspective of the evolving sedimentary succession -- Chapter12. Active tectonics of Himalayan frontal fault zone in the Sub Himalaya -- Chapter13. Late Quaternary evolution and morphostratigraphic development of the Ganga Plains -- Chapter14. Evolution and development of the Indian Monsoon -- Chapter15. Climate Change over the Indian sub-continent.
    Abstract: This book provides insights on new geological, tectonic, and climatic developments in India through a time progression from the Archean to the Anthropocene that are captured via authoritative entries from experts in earth sciences. This volume aims to bring graduate students and researchers up to date on the geodynamic evolution of the Indian Plate; concepts that have so far resulted in a rather uneven treatment of the subject at different institutions. The book is divided into 4 sections and includes perspectives such as the formation and evolution of the Indian crust in comparison to its neighbors such as Antarctica, Africa and Australia; the evolution of Precambrian cratons and sedimentary basins of India; and a summary account of early life reported in the Indian stratigraphic record. Readers will also discover the key recent research into the neotectonics, tectonic geomorphology, and paleoseismology of the Himalayan Front. Researchers and students in geology, earth sciences, sedimentology, paleobiology and geography will find this book appealing.
    Type of Medium: Online Resource
    Pages: VIII, 574 p. 173 illus., 139 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030159894
    Series Statement: Springer Geology,
    URL: https://doi.org/10.1007/978-3-030-15989-4
    DOI: 10.1007/978-3-030-15989-4
    DDC: 551
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    Water Resources of Italy : Protection, Use and Control (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Geology. ; Water. ; Hydrology. ; Pollution. ; Environment. ; Sustainability. ; Geology. ; Water. ; Pollution. ; Environmental Sciences. ; Sustainability.
    Description / Table of Contents: 1. Preface -- 2. Part I - Evolution of water management in Italy -- 3. Chapter 1. Italy’s outline M. Benedini -- 4. Chapter 2. Paradigm changes in water resources development G. Rossi -- 5. Chapter 3. Water Legislation: main innovation principles on water resources uses, pollution control and flood risk mitigation, G. Rossi -- 6. Chapter 4. Institutional framework of water governance: planning, service management and soil defense) G. Rossi -- 7. Part II - Water resources and water demands -- 8. Chapter 5. Conventional water resources (Surface and ground water resources) G. Rossi, M. Benedini -- 9. Chapter 6. Unconventional water resources (desalinated waters and treated wastewater reuse) G. Rossi, G. Cirelli -- 10. Chapter 7. Assessment of water requirements (domestic and urban uses; agricultural uses; industrial uses, navigation…) M. Benedini, R. Drusiani -- 11. Part III - Problems -- 12. Chapter 8. Management of municipal water services M. Di Natale, G. Rossi -- 13. Chapter 9. Water pollution control M. Benedini -- 14. Chapter 10. Water and electric power G. Ruggeri, M. Benedini -- 15. Chapter 11. Ecological in-stream flows (or water and environment) S. Alecci, G Rossi -- 16. Part IV – Challenges -- 17. Chapter 12. Mitigation of flood risk G. Rossi -- 18. Chapter 13. Coping with droughts G. Rossi -- 19. Chapter 14. Virtual water F. Laio, S. Tamea, M. Tuminetti -- 20. Chapter 15. Adaptations strategies to climate change in water resources D. Peres -- 21. Part V – Conclusions -- 22. Chapter 16. The future of water management in Italy M. Benedini, G. Rossi. .
    Abstract: This book offers a comprehensive framework of the current state of water resources in Italy and of the main stages of the evolutionary way in the last decades for achieving an integrated, sustainable and equitable water resources management. The main paradigms of water resources development are identified as: i) engineering and economic approach to water resources exploitation, ii) focus on pollution control and water-excess management, iii) a comprehensive approach toward a sustainable and equitable distribution of resources and effective risk reduction of water-related disasters. After a section devoted to the analysis of some historic stages in the legislation framework and the governance of water and soil, with particular reference to planning, design, building and operation of water systems, two sections deal with the estimation of water resources availability on national territory and estimation of water demands in municipal, agricultural, industrial, ecosystem sectors. The complex problems that the Italian society has to solve in the water field and the main challenges of a changing world are discussed in the fourth section of the volume. The book will not only be useful for water professionals, but also for citizen who like to discern the key factors which delay the recognition of water as a resource for life. The description of the problems and adopted solutions could also serve as a guideline for similar situations encountered in other countries, improving the preparation of the responsible people.
    Type of Medium: Online Resource
    Pages: XVII, 365 p. 97 illus., 80 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030364601
    Series Statement: World Water Resources, 5
    URL: https://doi.org/10.1007/978-3-030-36460-1
    DOI: 10.1007/978-3-030-36460-1
    DDC: 551
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    The Geoheritage of Hot Springs (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Geology. ; Conservation biology. ; Ecology . ; Geophysics. ; Physical geography. ; Geology. ; Conservation Biology. ; Geophysics. ; Earth System Sciences.
    Description / Table of Contents: Hot springs: A general perspective -- The geology of hot springs -- The geochemistry of hot springs -- The conservation of hot springs -- Hot springs throughout history -- Hot springs and their cultural heritage.
    Abstract: The aim of this book is to provide an overview of topics related to the extensive geoheritage of hot springs, their natural environments, and their integration into commercial and industrial functions. The eleven chapters explore aspects of historical and cultural traditions, geology and geochemistry, research updates, conservation issues and of course health, wellness, and recreation throughout time. Because natural hot springs and active hydrothermal areas play a significant role in the tourism industry, visitor expectations are examined together with an assessment of common hazards and potential risks in active hydrothermal environments, along with recommendations how to stay safe. For the purpose of showcasing certain unique features, to share noteworthy events and developments or to identify concerns associated with the sustainability of natural water source, examples of particular hot spring areas are included in several chapters. One chapter is also dedicated entirely to the protection of natural hot springs and raises awareness for conservation, while another chapter reviews the history of hot springs in great detail to establish a realistic and justifiable timeline of their original use. Lastly, the significance of natural hot springs for various tourism sectors is analysed and the potential for sustainable future destination development in rural and remote regions is discussed. Many locations were considered and invite the reader to use the information as a reference point in the quest to further explore the remarkable natural and cultural geoheritage of hot springs worldwide.
    Type of Medium: Online Resource
    Pages: XL, 383 p. 289 illus., 248 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030604639
    Series Statement: Geoheritage, Geoparks and Geotourism, Conservation and Management Series,
    URL: https://doi.org/10.1007/978-3-030-60463-9
    DOI: 10.1007/978-3-030-60463-9
    DDC: 551
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    Geological Resources of Tierra del Fuego (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Geology. ; Physical geography. ; Mineralogy. ; Geology. ; Earth System Sciences. ; Mineralogy.
    Description / Table of Contents: Chapter 1. An introduction to the geology of Tierra del Fuego -- Chapter 2. Beatriz Mine: a Polymetallic Massive Occurrence in Tierra del Fuego -- Chapter 3. A review of the Arroyo Rojo VMS deposit, Tierra del Fuego -- Chapter 4. The Ornamental Rocks of Tierra del Fuego -- Chapter 5. Aggregates in Tierra del Fuego: Morphogenesis and Distributio -- Chapter 6. Didactic Tools in the Scope of Geography in the Provincia de Tierra del Fuego -- Chapter 7. Teaching Earth Sciences in the Provincial Educational System -- Chapter 8. History of Gold in Tierra del Fuego -- Chapter 9. Isla Grande de Tierra del Fuego and Isla de los Estados Peatlands -- Chapter 10. Lakes and Glaciers from Fuegian Andes. Morphology, Distribution and Origin -- Chapter 11. Geophysical Methods Applied to the Study of Lakes and Paleolakes in Tierra del Fuego -- Chapter 12. Geological and Geographic Resources among Hunter-gatherers of Tierra del Fuego: a View from Archaeological and Ethnographic Data -- Chapter 13. Geotourism – Interpretation – Ethnogeology: Extraordinary Geological Resources in Tierra del Fuego -- Chapter 14. Key features and Geosite proposal to tell the story of the Argentinian Andes in the Isla Grande de Tierra del Fuego -- Chapter 15. Differential Uplifting Rates Across the Magellan Fault: Interactions Between South American and Scotia Plates -- Chapter 16. Paleomagnetic and Magnetic Studies of Quaternary Units in Tierra del Fuego, the South Atlantic Islands and Southern Patagonia -- Chapter 17. Provenance of the Coastal Sands of the Western Scotia Plate: Tierra del Fuego and Antarctic Peninsula -- Chapter 18. An overview on the Mineral Resources of the Argentine Antarctic Sector -- Chapter 19. Meteorites found in the Argentine Antarctic Sector -- Chapter 20. Acidity and Alkalinity as Foundational Parameters in the Ordering of Eruptive Rocks and some Fuegian examples.
    Abstract: The CADIC’s Geological Resources Program will soon turn 40 years of fruitful development. During this period many projects were carried out and others remain to be implemented. In the course of time three generations of researchers have been formed. Mentioning names would be unfair to those that could be involuntarily omitted. There is still a long way to go. The eagerness for knowledge should not stop. This book is a tribute to all those people who have worked in the different projects of pure and applied science, and educational, and human resources training, granted to this founding program and associated laboratories of the regional center of CONICET in Ushuaia, Tierra del Fuego, Argentina. The twenty papers which constitute this book have a genuine Latin appeal, having been written by 50 authors based in Argentina and Spain. All this contributions are concerned with Fuegian geological resources. Everyone concerned with this work hopes that it will prove a fitting and lasting memorial to Nacho Subías, whose personal contribution to our knowledge of this geology was outstanding.
    Type of Medium: Online Resource
    Pages: XII, 371 p. 173 illus., 136 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030606831
    Series Statement: Springer Geology,
    URL: https://doi.org/10.1007/978-3-030-60683-1
    DOI: 10.1007/978-3-030-60683-1
    DDC: 551
    Language: English
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    Emerging Technologies for Disaster Resilience : Practical Cases and Theories (2021)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Natural disasters. ; Sociology. ; Image processing Digital techniques. ; Computer vision. ; Social media. ; Natural Hazards. ; Sociology. ; Computer Imaging, Vision, Pattern Recognition and Graphics. ; Social Media.
    Description / Table of Contents: Existing, new and emerging technologies for Disaster Resilience -- Developing the eXtended tangible user interface as an experimental platform for Geo CPS -- Innovation in earthquake early warning system: A case study of EQ Guard -- Drones for disaster risk reduction and crisis response -- VR/ AR and its application to disaster risk reduction -- Communication structure, protocol and data model towards resilient cities in Japan -- A conceptual framework for designing an effective community resilience management system -- Social media and disaster management -- Use of IT for situation awareness for DRR -- Emergency communication and use of ICT in disaster management -- Experimental command and control center for crisis and disaster management: A Living-Lab approach -- Real-time mapping system of shelter conditions for safe evacuation -- Decision support system and new technologies. .
    Abstract: Technological advances have helped to enhance disaster resilience through better risk reduction, response, mitigation, rehabilitation and reconstruction. In former times, it was local and traditional knowledge that was mainly relied upon for disaster risk reduction. Much of this local knowledge is still valid in today’s world, even though possibly in different forms and contexts, and local knowledge remains a shared part of life within the communities. In contrast, with the advent of science and technology, scientists and engineers have become owners of advanced technologies, which have contributed significantly to reducing disaster risks across the globe. This book analyses emerging technologies and their effects in enhancing disaster resilience. It also evaluates the gaps, challenges, capacities required and the way forward for future disaster management. A wide variety of technologies are addressed, focusing specifically on new technologies such as cyber physical systems, geotechnology, drone, and virtual reality (VR)/ augmented reality (AR). Other sets of emerging advanced technologies including an early warning system and a decision support system are also reported on. Moreover, the book provides a variety of discussions regarding information management, communication, and community resilience at the time of a disaster. This book’s coverage of different aspects of new technologies makes it a valuable resource for students, researchers, academics, policymakers, and development practitioners.
    Type of Medium: Online Resource
    Pages: XIII, 260 p. 89 illus., 77 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811603600
    Series Statement: Disaster Risk Reduction, Methods, Approaches and Practices,
    URL: https://doi.org/10.1007/978-981-16-0360-0
    DOI: 10.1007/978-981-16-0360-0
    DDC: 551
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    Disaster Risk Reduction in Mexico : Methodologies, Case Studies, and Prospective Views (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Natural disasters. ; Geotechnical engineering. ; Emergency medical services. ; Industrial Management. ; Political science. ; Natural Hazards. ; Geotechnical Engineering and Applied Earth Sciences. ; Emergency Services. ; Industrial Management. ; Governance and Government.
    Description / Table of Contents: Preface -- Before the Disaster -- During the Disaster -- After the Disaster -- Ways to Create Resilience in the Economic Activities.
    Abstract: This book recognizes Mexico's effects and challenges in a natural disaster and offers empirical risk-reduction methods in critical cases. The proposals considered here include real and detailed analysis, a set of models, frameworks, strategies, and findings in the three stages of the disaster (before–during–after). This book: describes the methodology to find secure locations for the Regional Humanitarian Response Depot; offers recommendations for the sites and creation of an Export Logistics Cluster; shows how to use available technology and information to locate volunteers in the right spots describes mathematical models to help to allocate procedure of resources for restoring the affected community and proposes actions to create resilience in the country's main economic sectors, including agriculture and industry. The processes applied at recent disasters such as the 19S earthquake and their results are used as case studies, identifying possibilities for further improvement. The book also describes new trends for Mexico due to climate change and makes suggestions for mitigating future disasters. The proposals are also replicable to other highly populated societies with similar socio-economic structures. Finally, this book is the basis for generating more innovative recommendations by researchers, graduate students, academics, professionals, and practitioners to obtain better planning and better collaboration between all the humanitarian chain actors. This book intends to be of interest as a fundamental tool for decision-makers, governments, non-governmental organizations, and enterprises.
    Type of Medium: Online Resource
    Pages: XII, 380 p. 108 illus., 66 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030672959
    URL: https://doi.org/10.1007/978-3-030-67295-9
    DOI: 10.1007/978-3-030-67295-9
    DDC: 551
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  • 79
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    The Geology of Iran: Tectonic, Magmatism and Metamorphism (2021)
    Cham :Springer International Publishing :
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    Keywords: Geology. ; Geomorphology. ; Sedimentology. ; Geology. ; Geomorphology. ; Sedimentology.
    Description / Table of Contents: Geological setting and crustal structure of Iran -- Structural units of Iran -- Faults and Tectonic Phases of Iran -- Magmatic Phases and their Distribution in Iran -- Intrusive Rocks of Iran -- Ophiolite Complexes in Iran -- Metamorphic Rocks of Iran.
    Abstract: This book describes the geological setting of Iran throughout geological history, referring to paleogeography and general geodynamics. Also, all structural units, faults, tectonic phases and orogeny occurred in the geology of Iran have been evaluated. Magmatic and metamorphic rocks along with ophiolitic complexes have extensive outcrops in Iran, and these rocks with Precambrian age constitute its basement. Study and identification of such rocks not only throws light on the geodynamic issues of Iran but also helps in recognition of the mode of formation and evolution of the sedimentary basins located within various structural divisions of the country. Moreover, the majority of metallic and non-metallic mineral deposits are associated either directly or indirectly with magmatic, and at time metamorphic, rocks. In the Magmatism and Metamorphism parts, it is tried to thoroughly consider the various aspects of the igneous rocks, whether intrusive, extrusive or young volcanoes, from the point of view of petrography, geochemistry and geodynamics. In addition, the major intrusive bodies of Iran have been presented along with their petrologic and chronologic specifications in tables, mentioning the bibliographic resources.
    Type of Medium: Online Resource
    Pages: XII, 441 p. 134 illus., 96 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030711092
    Series Statement: Earth and Environmental Sciences Library,
    URL: https://doi.org/10.1007/978-3-030-71109-2
    DOI: 10.1007/978-3-030-71109-2
    DDC: 551
    Language: English
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  • 80
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    Fire Science : From Chemistry to Landscape Management (2021)
    Cham :Springer Nature Switzerland :
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    Keywords: Natural disasters. ; Fire prevention. ; Buildings Protection. ; Environment. ; Forestry. ; Environmental health. ; Ecology . ; Natural Hazards. ; Fire Science, Hazard Control, Building Safety. ; Environmental Sciences. ; Forestry. ; Environmental Health. ; Ecology.
    Description / Table of Contents: Part I: Introduction -- Part II: Combustion and Heat transfer processes -- Chapter 1: Ignition: Chemical Conditions -- Chapter 2: Chemical Processes: From Fuel to Smoke -- Chapter 3: Heat Production.-Chapter 4: Heat for pre-ignition and flames.-Chapter 5: Heat transfer.-Part III: Vegetation fuels, fire behavior and effects.-Chapter 6: Fuels and fire behavior description.-Chapter 7: Fire Propagation.-Chapter 8: Extreme Fire Behavior -- Chapter 9: Fire Effects on Plants, Soils and Animals.-Chapter 10: Fire and people -- Part IV: Managing fuels, fires and landscapes -- Chapter 11: Fuel dynamics and management.-Chapter 12: Fire regimes, landscape dynamics and landscape management.-Chapter 13: Integrated Fire Management -- Chapter 14: Futuring: Trends in Fire Science and Management.
    Abstract: This textbook provides students and academics with a conceptual understanding of fire behavior and fire effects on people and ecosystems to support effective integrated fire management. Through case studies, interactive spreadsheets programmed with equations and graphics, and clear explanations, the book provides undergraduate, graduate, and professional readers with a straightforward learning path. The authors draw from years of experience in successfully teaching fundamental concepts and applications, synthesizing cutting-edge science, and applying lessons learned from fire practitioners. We discuss fire as part of environmental and human health. Our process-based, comprehensive, and quantitative approach encompasses combustion and heat transfer, and fire effects on people, plants, soils, and animals in forest, grassland, and woodland ecosystems from around the Earth. Case studies and examples link fundamental concepts to local, landscape, and global fire implications, including social-ecological systems. Globally, fire science and integrated fire management have made major strides in the last few decades. Society faces numerous fire-related challenges, including the increasing occurrence of large fires that threaten people and property, smoke that poses a health hazard, and lengthening fire seasons worldwide. Fires are useful to suppress fires, conserve wildlife and habitat, enhance livestock grazing, manage fuels, and in ecological restoration. Understanding fire science is critical to forecasting the implication of global change for fires and their effects. Increasing the positive effects of fire (fuels reduction, enhanced habitat for many plants and animals, ecosystem services increased) while reducing the negative impacts of fires (loss of human lives, smoke and carbon emissions that threaten health, etc.) is part of making fires good servants rather than bad masters.
    Type of Medium: Online Resource
    Pages: XXXVIII, 644 p. 326 illus., 243 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030698157
    Series Statement: Springer Textbooks in Earth Sciences, Geography and Environment,
    URL: https://doi.org/10.1007/978-3-030-69815-7
    DOI: 10.1007/978-3-030-69815-7
    DDC: 551
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    Ecosystem-Based Disaster and Climate Resilience : Integration of Blue-Green Infrastructure in Sustainable Development (2021)
    Singapore :Springer Nature Singapore :
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    Keywords: Natural disasters. ; Biotic communities. ; Environmental sciences Social aspects. ; Urban ecology (Biology). ; Environment. ; Water. ; Hydrology. ; Natural Hazards. ; Ecosystems. ; Environmental Social Sciences. ; Urban Ecology. ; Environmental Sciences. ; Water.
    Description / Table of Contents: Uncertainties in Urbanizing World and Nature-based resilience building -- Ecosystem-based Adaptation (EbA) in the Hindu Kush Himalayas: Status, progress and challenges -- Evaluation of Ecosystem based approaches for disaster and climate risk resilience and policy perspectives in Pakistan -- Ecosystem-based approaches and policy perspectives in Nepal -- Ecosystem-based approaches and policy perspective from India -- Ecosystem-based approaches and policy perspectives: Towards integrated blue-green solutions in Vietnam -- Turning blue, green and gray: opportunities for blue-green infrastructure in the Philippines -- Making resilience a reality: The contribution of Peri-urban ecosystem services (BGI) to Urban resilience -- Innovations to Reduce Disaster Risks of Water Challenges -- Future heat risk in South Asia and the need for ecosystem mitigation -- Urban Risk Assessment Tools and Techniques for Ecosystem-based Solutions, India -- Scaling-up Nature based Solutions for mainstreaming urban resilience in Indian cities -- Incorporation of BIM based modeling in sustainable development of green building from stakeholders’ perspective -- Planning for Climate Change Adaptation: Comprehensive Approach for Smart Urban Areas Management -- Path towards sustainable water management: A case study of Shimla, India -- Application of Remote Sensing Image in ECO-DRR for Dehradun City -- Ecosystem-based approaches for water stress management- lessons from Nagpur Metropolitan Area, India -- Challenges in decision-making for building resilience to climate risks -- A “Greener” alternative: The Sri Lankan experience of Eco-DRR -- the Watarase retarding basin—a historical example of ecosystem-based disaster risk reduction in Japan -- Self-efficacy for EbA and human health in a post-disaster recovery phase -- Freshwater biomonitoring: an ecosystem-based approach (EbA) for building climate resilience communities in Fiji -- Forward Looking Lens to Mainstream Blue-Green Infrastructure.
    Abstract: This book provides an introduction to the critical role of ecosystem-based disaster risk resilience (Eco-DRR) for building community resilience to multiple environmental risks such as rising heat, water stress, and pollution. Blue-green infrastructure (BGI) is an Eco-DRR tool that is an under-explored paradigm and can respond as one common strategy to targets set by the Sustainable Development Goals (UNDP), Climate Agreements (UNEP), the Sendai Framework (UNISDR), and the New Urban Agenda (UNCHS). Highlighted here in a systematic way is the importance of blue-green infrastructures in resilience building. The purpose is to introduce readers to the challenging context of development and opportunity creation for Eco-DRR. The roles of policy, scientific research, and implementation are presented cohesively. An attractive proposition of the book is a collection of case studies from different parts of the world where integration of BGI is experimented with at various levels of success. It envisages that shared tacit experiences from the realm of practice will further strengthen explicit knowledge. The focus in this book is on need and context building, policy and science (investigation, analysis, and design), case studies, and a road map for the future in four successive parts. Each part is self-sufficient yet linked to its predecessor, successor, or both, as the case may be.
    Type of Medium: Online Resource
    Pages: XVII, 512 p. 136 illus., 120 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811648151
    Series Statement: Disaster and Risk Research: GADRI Book Series,
    URL: https://doi.org/10.1007/978-981-16-4815-1
    DOI: 10.1007/978-981-16-4815-1
    DDC: 551
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    Surface Ruptures Associated with the 2016 Kumamoto Earthquake Sequence in Southwest Japan (2022)
    Singapore :Springer Nature Singapore :
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    Keywords: Geology. ; Natural disasters. ; Geomorphology. ; Sedimentology. ; Geology. ; Natural Hazards. ; Geomorphology. ; Sedimentology.
    Description / Table of Contents: Geomorphology and Geology -- Seismicity and Crustal Movement -- Active Faults and Paleoseismicity -- Seismological and Geodetic Observations of the 2016 Kumamoto Earthquake Sequence -- Field Mapping Methods and Data Compilation Procedures of the Surface Ruptures -- General Characteristics of the Surface Ruptures of the 2016 Kumamoto Earthquake Sequence -- Surface Ruptures of the Shirahata-Oike Section -- Surface Ruptures along the Kita-Amagi Fault Zone -- Surface Ruptures along the Southern Part of the Futagawa Fault -- Surface Ruptures along the Central-Northern Part of the Futagawa Fault -- Surface Ruptures in the Downtown of Kumamoto City -- Surface Ruptures and Tectonic Geomorphology along and around the Idenokuchi Fault -- Surface Ruptures in the Northwestern Part of the Inner Aso Caldera -- Surface Ruptures in the Northeastern Part of the Inner Aso Caldera -- Surface Ruptures in the Northwest of the Outer Aso Caldera -- Surface Ruptures along the Western Part of the Bungo-Kaido Road -- Surface Ruptures in Mashiki Town: Tectonic Significance and Building Damage -- Surface Ruptures Accompanied with the Largest Foreshock.
    Abstract: In April 2016, a series of earthquakes hit the Kumamoto area of Kyushu Island, southwest Japan. The Mj 7.3 (Mw 7.0) mainshock produced extensive and complex surface ruptures in and around the active Futagawa-Hinagu fault zone, including primary right-lateral faulting, slip-partitioned normal faulting, and distributed and triggered surface breaks, as well as minor surface ruptures associated with the foreshocks of up to Mj 6.5 (Mw 6.2). This book provides a complete record of those surface ruptures mapped by a team of more than 25 researchers from Japanese universities and research institutes. The locations, traces, morphology, and displacement are described in great detail along with over 300 on-site photographs, and the information is supplemented by the GIS data available online. The book is useful for a wide range of earthquake scientists and engineers who work on active faults and related seismic hazard assessment, including earthquake geologists, tectonic geomorphologists, seismologists, geodesists, civil engineers, and city planners.
    Type of Medium: Online Resource
    Pages: VIII, 241 p. 415 illus., 409 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811911507
    Series Statement: Advances in Geological Science,
    URL: https://doi.org/10.1007/978-981-19-1150-7
    DOI: 10.1007/978-981-19-1150-7
    DDC: 551
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    Wildland Fire Smoke in the United States : A Scientific Assessment (2022)
    Cham :Springer International Publishing :
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    Keywords: Natural disasters. ; Fire ecology. ; Forestry. ; Pollution. ; Biology. ; Earth sciences. ; Geography. ; Natural Hazards. ; Fire Ecology. ; Forestry. ; Pollution. ; Biological Sciences. ; Earth and Environmental Sciences.
    Description / Table of Contents: Chapter 1. Assessing the State of Smoke Science -- Chapter 2. Fuels and Consumption -- Chapter 3. Fire Behavior and Heat Release as Source Conditions for Smoke -- Chapter 4. Smoke Plume Dynamics -- Chapter 5. Emissions -- Chapter 6. Smoke Chemistry -- Chapter 7. Social, Economic, and Health Effects of Smoke -- Chapter 8. Resource Manager Perspectives on the Need for Smoke Science -- Appendix A: Regional Perspectives on Smoke Issues and Management -- Appendix B: Smoke Monitoring Networks, Models, and Mapping Tools.
    Abstract: This open access book synthesizes current information on wildland fire smoke in the United States, providing a scientific foundation for addressing the production of smoke from wildland fires. This will be increasingly critical as smoke exposure and degraded air quality are expected to increase in extent and severity in a warmer climate. Accurate smoke information is a foundation for helping individuals and communities to effectively mitigate potential smoke impacts from wildfires and prescribed fires. The book documents our current understanding of smoke science for (1) primary physical, chemical, and biological issues related to wildfire and prescribed fire, (2) key social issues, including human health and economic impacts, and (3) current and anticipated management and regulatory issues. Each chapter provides a summary of priorities for future research that provide a roadmap for developing scientific information that can improve smoke and fire management over the next decade.
    Type of Medium: Online Resource
    Pages: XVI, 341 p. 63 illus., 50 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030870454
    URL: https://doi.org/10.1007/978-3-030-87045-4
    DOI: 10.1007/978-3-030-87045-4
    DDC: 551
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    Mars: A Volcanic World (2021)
    Cham :Springer International Publishing :
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    Keywords: Geology. ; Astronomy. ; Earth sciences. ; Geochemistry. ; Geology. ; Astronomy, Cosmology and Space Sciences. ; Earth Sciences. ; Geochemistry.
    Description / Table of Contents: Chapter 1 - History of scientific studies and current views of Mars -- Chapter 2 - The formation of Mars and the origin of its volcanic provinces -- Chapter 3 - Petrologic evolution of Martian volcanism and clues from meteorites -- Chapter 4 - Volcanic eruptions on Mars, lava flow morphology, and thermodynamics -- Chapter 5 - Volcanic Channels and Volcanic Features on Mars -- Chapter 6 - General concepts on porous-media flow on Mars – thermal H2O-CO2-fers – -- Chapter 7 - Buried volcano-hydrothermal systems and minerals on Mars -- Chapter 8 - Explosive volcanism on Mars -- Chapter 9 - The origin and evolution of volcanism at Martian highland paterae: A review of the current state of knowledge -- Chapter 10 - Infrasound Propagation on Mars atmosphere -- Chapter 11 - Potential Futures in Human Habitation of Martian Lava Tubes -- Chapter 12 - Future perspectives of Mars after the latest studies.
    Abstract: This book is a comprehensive advancement about the understanding of the volcanology of Mars in all its aspects, from its primary formation to its evolution in time, from the smaller structures to the bigger structures. It discusses the implications of volcanism in the general environmental and geological context of Mars. The book is validating the Southern Giant Impact Hypothesis explaining the formation of Mars in an interdisciplinary approach, including mineralogical, geochemical, volcanological as well as geomorphological information. Implications for future explorations in terms of resources are provided. This book serves as a textbook for undergraduate and graduate level to foster new basic research in the field of planetary volcanology and is a new guide for future missions toward a volcanic world, including new detailed information for the general audience who is always keen to know more about the history of Mars and its large volcanoes. The book also presents an updated situation about the water resources of the planet.
    Type of Medium: Online Resource
    Pages: VIII, 327 p. 138 illus., 107 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030841034
    URL: https://doi.org/10.1007/978-3-030-84103-4
    DOI: 10.1007/978-3-030-84103-4
    DDC: 551
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    Himalayan Thick-Skin Basement Deformation of the Ladakh Batholith, Leh-Ladakh Region, NW India (2023)
    Cham :Springer Nature Switzerland :
    Details
    Keywords: Geology. ; Geodynamics. ; Geomorphology. ; Physical geography. ; Geology. ; Geodynamics. ; Geomorphology. ; Physical Geography.
    Description / Table of Contents: 1. Geo-tectonic and, topographic, and geographical setting of the Leh-Ladakh region: study scope and methodology -- 2. Overview of the Geology, Structure, and Tectonics of the Ladakh Batholith and Indus Suture Rocks -- 3. Geology and Lithological Variations of the Ladakh Batholith within the Leh-Ladakh Region -- 4. Structural Geology of the High Strain Zone: Ladakh Batholith, Leh Region, NW India -- 5. Structural Geology of the Northern and North-Eastern Zone (N-NE Zone), Leh-Ladakh Region.
    Abstract: This book presents the first report and interpretation of the deformation, structural style, and geo-tectonic evolution of a 600km2 area of the Ladakh batholith, NW India, centred on the city of Leh, Ladakh. The Ladakh (and westerly Kohistan ) batholith comprises a large component of the Jurassic-Oligocene Kohistan-Ladakh Arc-Terrane (KLA), with magmatism spanning island arc, continental margin, and post-Himalayan collision tectonic environments. The KLA is bounded to the north by the Shyok-Northern Suture and to the south by the Indus Suture. The batholith illustrates basement thick-skin tectonic deformation and is divided/partitioned into a series of crustal blocks separated by lateral accommodation structures which allow independent movement in horizontal and vertical space. Thin skinned deformation within the adjacent sedimentary molasse Indus Suture Rocks produced large thrust stacks that predominantly moved towards the N-NE. Whilst deformation within cover sequences influences the basement structures, and helps break up the basement into crustal blocks, there is a clear distinction in deformation between the basement and cover sequences. Basement batholith deformation is more complex and heterogeneous, reflecting the variable transmission of tectonic stress within crystalline crust and the presence of a wide range of precursory inherited weaknesses and anisotropies. Models of time-space deformation are presented using data derived from field and extensive photograph / photo-mosaic image interpretation. The batholith was deformed during at least Palaeocene-Pliocene times at crustal depths that correspond to the ductile-brittle transition zone and shallower.
    Type of Medium: Online Resource
    Pages: XLV, 149 p. 136 illus., 135 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031315664
    Series Statement: Springer Geology,
    URL: https://doi.org/10.1007/978-3-031-31566-4
    DOI: 10.1007/978-3-031-31566-4
    DDC: 551
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    Problems of Geocosmos–2020 : Proceedings of the XIII International Conference and School (2022)
    Cham :Springer International Publishing :
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    Keywords: Geology. ; Solar system. ; Astronomy. ; Environmental sciences. ; Physics. ; Geology. ; Space Physics. ; Astronomy, Cosmology and Space Sciences. ; Environmental Physics.
    Abstract: This book addresses the problems of Geocosmos and provides a snapshot of the current research in a broad area of Earth Sciences carried out in Russia and elsewhere. The themes covered include solar physics, physics of magnetosphere, ionosphere and atmosphere, solar-terrestrial coupling links, seismology, geoelectricity, paleomagnetism and rock magnetism, as well as cross-disciplinary studies. The proceedings are carefully edited, providing a panoramic outlook of a broad area of Earth Sciences. The readership includes colleague researchers, students and early career scientists. The proceedings will help the readers to look at their research fields from various points of view. Problems of Geocosmos conferences are held by Earth Physics Department, St. Petersburg University bi-annually since 1994. It is the largest forum of this kind in Russia/former Soviet Union attracting up to 200 researchers in Earth and magnetospheric physics.
    Type of Medium: Online Resource
    Pages: XII, 495 p. 235 illus., 188 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030914677
    Series Statement: Springer Proceedings in Earth and Environmental Sciences,
    URL: https://doi.org/10.1007/978-3-030-91467-7
    DOI: 10.1007/978-3-030-91467-7
    DDC: 551
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    Geology and Geochemistry of Molybdenum Deposits in the Qinling Orogen, P R China (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Geology. ; Geochemistry. ; Mineralogy. ; Petrology. ; Geology. ; Geochemistry. ; Mineralogy. ; Petrology.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. Mining and the nature of gold deposits -- Chapter 3. Data to processes, examples, and discovery -- Chapter 4. Provinciality of goldfields -- Chapter 5. Enrichment of gold above background -- Chapter 6. Segregation of gold from base metals -- Chapter 7. Timing of deposit formation -- Chapter 8. Ore fluid types as recorded in fluid inclusions -- Chapter 9. Commonality and diversity: both need explanation. Chapter 10. Magmatic processes that lead to gold-only deposits -- Chapter 11. Fluids in the earth’s crust -- Chapter 12. Alteration in gold-only deposits -- Chapter 13. Case study: the formation of a giant goldfield: Kalgoorlie, Western Australia -- Chapter 14. Hydrothermal transport of gold -- Chapter 15. Metamorphic processes leading to gold-only deposits -- Chapter 16. Modification of deposits at high temperature -- Chapter 17. Formation and modification of deposits at lower temperatures -- Chapter 18. Carlin, Witwatersrand and some other gold-only examples -- Chapter 19. Gold-plus Copper-Gold deposits -- Chapter 20. Discoveries and the role of science in the Yilgarn goldfields of Western Australia -- Chapter 21. Discovery of Fosterville Deeps, Victorian Gold Province: long term science. Chapter 22. Summary and conclusions.
    Abstract: This book is the first systematic treatise of available data and view-points obtained from geological and geochemical studies of the Mo deposits in Qinling Orogen, China. Qinling Orogen has a minimum reserve of 8.7 Mt Mo, ranking the largest molybdenum province both in China and the world. Incorporating all known Mo deposit types in the world, it presents extensive studies of Mo deposits of world-class and unusual types within tectonic settings. The Qinling Orogen was finally formed during continental collision between Yangtze and North China cratons, following the Triassic closure of the northernmost paleo-Tethys. It hosts 49 Mo deposits formed in seven mineralization events since 1850 Ma, with all the world-class deposits being formed during 160-105 Ma, coeval with collisional orogeny. These deposits are assigned to magmatic and metamorphic hydrothermal classes. The magmatic hydrothermal class includes porphyries, skarns, and intrusion-related veins (carbonatite, fluorite and quartz). The porphyry Mo systems in Qinling Orogen are predominated by Dabie-type formed in continental collision setting, followed by Endako- and Climax-types formed in continental arcs and rifts, respectively. The metamorphic hydrothermal Mo deposits are only reported in Qinling Orogen, and thus a new crustal continuum model for the orogenic class mineral systems is proposed. A scientific linkage between ore geology and fluid inclusions is introduced and verified both by theory and case studies. This is the first research book comprehensively displaying continental collision metallogeny. This literature will benefit both Western and Chinese mineral explorers and miners, as well as research scientists and students.
    Type of Medium: Online Resource
    Pages: XVIII, 842 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811648717
    Series Statement: Modern Approaches in Solid Earth Sciences, 22
    URL: https://doi.org/10.1007/978-981-16-4871-7
    DOI: 10.1007/978-981-16-4871-7
    DDC: 551
    Language: English
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    Climate, Environment and Disaster in Developing Countries (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Natural disasters. ; Climatology. ; Environmental geography. ; Human ecology Study and teaching. ; Sustainability. ; Geographic information systems. ; Natural Hazards. ; Climate Sciences. ; Integrated Geography. ; Environmental Studies. ; Sustainability. ; Geographical Information System.
    Description / Table of Contents: Challenges of Climate Resilient Livelihoods and an Inquiry of Mitigation Strategies in India -- Analysing LULC change on runoff and sediment yield in urbanizing agricultural watershed of monsoonal climate river basin in West Bengal, India -- Remote Sensing Based Analysis of Relationship between Urban Heat Island and Land Use/Cover Type in Bhubaneswar Metropolitan Area, India -- Statistical Downscaling method for Improving Global Model Rainfall forecasts of seasonal rainfall over West Bengal (WB), India -- Identification of Climate Change Vulnerable Zones in Bangladesh through Multivariate Geospatial Analysis -- Water Scarcity in Coastal Bangladesh: Search for Arsenic-safe Aquifer with Geostatistics -- Biodiversity Degradation of Southwestern Region in Saudi Arabia -- Causes and Effects of Water Logging in Dhaka City -- Water Resource Development and Sustainable Initiatives of India: Present and Future -- Mapping and Reclamation of Wastelands in Drought-prone Purulia District of West Bengal, India using Remote Sensing and GIS -- Soil, water salinization and its impact on household food insecurity in the Indian Sundarbans -- Impact of Water Reservoir and Irrigation Canals on Land Use and Land Cover Changes in Upper Kumari River Basin, West Bengal, India -- Spatial pattern of Arsenic contamination in floodplain aquifers, western bank of Bhagirathi River, Lower Ganges Delta, West Bengal, India -- Spatial Pattern of Groundwater Depletion, Its Access and Adaptive Agricultural Strategies in Barddhaman District, West Bengal, India -- Detection of Land Use/Land Cover Changes of Irga Watershed in the North-Eastern Fringe of Choto Nagpur Plateau, Jharkhand, India -- An Analytical Study on Interplay between Physiographic Condition and Land Use Land Cover Dynamicity -- Assessment of Land use and Land cover change dynamics using remote sensing and GIS techniques in most effected parts of Rajpur-Sonarpur municipality -- Disaster Risk Reduction in the Changing Scenario -- Exploring the Impacts of River Morphology Change Associated Natural Disasters on Teesta Riparian Environment of Bangladesh -- An Assessment on Effects of Coastal Erosion on Coastal Environment: A Case Study in Coastal Belt between Kalu River mouth and Bologoda River mouth, Sri Lanka -- Vulnerability and Exposures to Landslides in the Chittagong Hill Tracts, Bangladesh: A Case Study of Rangamati Town for Building Resilience -- Hydrometeorological Analysis of the 2015 Rarh Bengal Flood in the Lower Gangetic Plain of India: Exceptional, Fast and Furious -- Application of Remotely Sensed Data for Estimation of Indices to Assess Spatiotemporal Aspects of Droughts in Bankura District of West Bengal, India -- Temporal variability of discharge and suspended sediment transport in the Subarnarekha River Basin, eastern India: A geomorphic perspective -- Assessment of Jiadhal River Basin using Sedimentary Petrology and Geospatial Approach -- An Assessment of RUSLE Model and Erosion Vulnerability in the Slopes of Dwarka – Brahmani Lateritic Interfluve, Eastern India -- Urban Flooding Scenario and Human Response in Guwahati, India.
    Abstract: The world is currently experiencing changes in climate and environment that often lead to natural disasters. Nearly three million people worldwide may have been killed in the past 20 years by natural disasters. In total, 90% of the natural disasters and 95% of all disaster-related deaths occur in the developing countries. Recently such problems have accelerated due to LULC change, biodiversity degradation, increased tourism, urbanization and climate change. This book, consisting of 27 chapters, explores the topics of climate, environment and natural disasters in developing countries. It is essential to discuss these diverse issues in the field of geography as it encompasses interdisciplinary topics. The range of issues on national, regional and local dimensions is not only confined to geography but also concerned to other disciplines as well. Therefore, this book is a valuable source for scientists and researchers in allied fields such as climatology, disaster management, environmental science, hydrology, agriculture, and land use studies, among other areas. Furthermore, this book can be of immense help to the planners and decision-makers engaged in dealing with the problems of climate, environmental change and natural disasters in developing countries.
    Type of Medium: Online Resource
    Pages: XXX, 522 p. 220 illus., 211 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811669668
    Series Statement: Advances in Geographical and Environmental Sciences,
    URL: https://doi.org/10.1007/978-981-16-6966-8
    DOI: 10.1007/978-981-16-6966-8
    DDC: 551
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  • 89
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    Disaster Management in the Complex Himalayan Terrains : Natural Hazard Management, Methodologies and Policy Implications (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Natural disasters. ; Geomorphology. ; Geography. ; Physical geography. ; Geographic information systems. ; Natural Hazards. ; Geomorphology. ; Geography. ; Physical Geography. ; Geographical Information System.
    Description / Table of Contents: Part-A: Introduction to the Disasters and Hazards in the Himalayan Terrains -- 1. Disasters in the Complex Himalayan Terrains -- 2. Hazards in the perspective of Himalayan Terrain: A review -- Part-B: Landslides in the Himalayas – Causes and Consequences -- 3. Himalayan Landslides – Causes and Evolution -- 4. Landslides in the Himalayas: Causes, Evolution, and Mitigation – A Case Study of National Highway 44, India -- 5. Geo-environmental Impact of Road Widening Project along the National Highway- 44A, Jammu & Kashmir, India -- Part-C: Floods in the Himalayas – Causes and Consequences -- 6. September 2014 floods in Kashmir Himalaya - Impacts and Mitigation Strategy -- 7. A review on the estimation of Glacial Lake Outburst Floods (GLOFs) in the Himalayan region using remote sensing and geographic information system -- 8. Impact of Floods on the Green Energy Sector in the Himalayas using remote sensing and geographic information system (GIS) – A case study of Gagas Watershed, Uttarakhand, India -- Part-D: Earthquakes in the Himalayas – Assessment and Forecasting -- 9. Synthetic Aperture Radar Interferometry to Measure Earthquake Related Deformation: A Case Study from Nepal -- 10. Earthquake Forecasting in the Himalayas using Artificial Neural Networks -- Part-E: Hazard mitigation strategies in the Himalayas -- 11. Forest Fire Alert System of India with a Special Reference to Fire Vulnerability Assessment of the UT of Jammu and Kashmir -- 12. Hazard mitigation and climate change in the Himalayas – Policy and Decision making.
    Abstract: South Asia, harboring the complex Himalayan terrains, has over one-fifth of the world’s population and is recognized as the most hazard-prone region of the world. The exponential increase in population with the consequent pressure on natural resources and continued high rates of poverty and food insecurity also makes this region the most vulnerable region to hazards in the world as far as the impacts of climate change are concerned. Over the last century, the climatic trends in South-Asia have been observed to be characterized by increasing air temperatures and an increasing trend in the intensity and frequency of extreme events. IPCC (2014) has reported that the Himalayan highlands shall face significant warming over the next century. The increasing frequency of natural hazards due to the impacts of climate change in the Himalayas calls for efficient management and policymaking in these regions, which can only be implemented by the local governments through an established science-based robust action plan. This edited volume focuses on the management of natural hazards using innovative techniques of spatial information sciences and satellite remote sensing. It contains chapters from eminent researchers and experts in the field of hazard management, remote sensing, and GIS. The primary focus of this book is to replenish the gap in the available literature on the subject by bringing the concepts, theories, and practical experiences of the specialists and professionals in this field together in one volume to help students, researchers, and policymakers to address issues concerning management and policy implications of natural hazards in the complex Himalayan region.
    Type of Medium: Online Resource
    Pages: XI, 182 p. 76 illus., 65 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030893088
    Series Statement: Geography of the Physical Environment,
    URL: https://doi.org/10.1007/978-3-030-89308-8
    DOI: 10.1007/978-3-030-89308-8
    DDC: 551
    Language: English
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  • 90
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    Urban Design in Seismic-Prone Regions (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Natural disasters. ; Engineering design. ; Natural Hazards. ; Engineering Design.
    Description / Table of Contents: Urban design and natural disasters -- Definitions and concepts -- Manjil earthquake of June 20, 1990, lesson learned from experience -- Design at macro scale: Urban design in a seismic-prone city -- Urban design solutions to mitigate seismic risk at the small scale: Rasht city center -- Creating open spaces and modification of access networks--the case of the central area of the city of Rasht -- Urban design guidelines in the seismic-prone regions -- Conclusion -- Epilogue: Natural disasters, sustainability, resilience, cities and Covid 19.
    Abstract: This book presents practical guidelines and recommendations for the design in seismic-prone regions. It is based on extensive research and it includes original drawings and sketches at the macro and micro levels. It is the first time that an attempt has been made to publish a book on urban design in the seismic-prone regions, covering the needs of government officials, planners, economists, architects, engineers and scientists, with the purpose of planning for seismic risk reduction and the practical implementation of method­ologies and findings in earthquake affected regions. The guidelines presented are expected to be immensely beneficial to all countries in the earth­quake prone regions, particularly in the developing world.
    Type of Medium: Online Resource
    Pages: X, 338 p. 257 illus., 29 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031083211
    Series Statement: The Urban Book Series,
    URL: https://doi.org/10.1007/978-3-031-08321-1
    DOI: 10.1007/978-3-031-08321-1
    DDC: 551
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    Challenges of Disasters in Asia : Vulnerability, Adaptation and Resilience (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Natural disasters. ; Climatology. ; Natural Hazards. ; Climate Sciences.
    Description / Table of Contents: Probabilistic Seismic Hazard Assessment for the Frontal Part of the Mishmi Hills, India and Its Role in Disaster Management -- Assessment of Desertification and Land Degradation Vulnerability in Humid Tropics and Sub-Tropical Regions of India Using Remote Sensing & GIS Techniques -- Analysis of Diversified Impact of Covid-19 Pandemic Across the Indian States -- Spatio-Temporal Analysis of Seasonal Drought Pattern Using Vegetation Condition Index in Latur District -- Sea Level Rise and Impact on Moushuni Island of Sundarban Delta (West Bengal) – A Geospatial Based Approach -- Mapping of Affected Areas by Extreme Weather Events in Kanda Tehsil of Bageshwar District by GIS and RS Technique -- Household Based Approach to Assess the Impact of Riverbank Erosion on Socio-Economic Condition of People: A Case Study of Lower Ganga Plain -- Landslide Susceptibility Mapping of East Sikkim Employing AHP Method -- Socio-Environmental Vulnerability of Agriculture Communities to Climate Change in Western Himalaya – A Household Level Review -- Application of Mike 11 for One Dimensional GLOF Modeling of a Rapidly Expanding Dalung Proglacial Lake, Indus River Basin, Western Himalaya -- Hybrid Tree-based Wetland Vulnerability Modelling -- Spatio-temporal Analysis of Landuse Landcover Change Using STAR Method in Kolkata Urban Agglomeration -- Vulnerability Assessment of COVID Epidemic for Management and Strategic Plan– A Geospatial Based Solution -- Auto Generated Gravity Canal Routes for Flood Mitigation and Groundwater Rejuvenation: A study in Damodar - Barakar River Basin, India -- Assessing the Impact of Disasters and Adaptation Strategies in Sundarban Biosphere Reserve, India: A Household Level Analysis -- Forest Fires in Tropical Deciduous Forests – A Precursor to Anticipatory Adaptation Framework -- Understanding the Flood Early Warning System, A Case Study of Trans-boundary Water Governance in the Gandak River Basin -- Adaptation Policy and Community Discourse of Climate Change in the Mountainous Regions of India -- Analysis of Public Awareness, Health Risks and Coping Strategies against Heat waves in NCT of Delhi, India -- Community Based Flood Preparedness: A case study of Adayar watershed, Chennai city, Tamil Nadu, India -- Building Resilience and Management of Vulnerability: Solution for Reduction of Risk of Disasters -- Employability, A Key to Community’s Socio-economic Malady of Pandemic Proportions -- Living with Floods: Community Based Coping and Resilience mechanism of Mising/Mishing from Floods - A Study of Majuli District of Assam -- Assessment of Public Perception on Designing Colombo Municipal Council Area as a Green City -- Climate Change and Its Impacts assessment through Geospatial technology-A Theoretical Study from Extreme Weather Perspective for Disasters Resilient India -- Corporate Sector and Disaster Risk Management: A Critical Analysis with Reference to Corporate Social Responsibility Law in India -- Impact of Training and Awareness Programmes of Community Volunteers in Disaster Risk Reduction and Response- A Study of Srinagar City.
    Abstract: The book provides an understanding about the disaster impacts, vulnerability assessment, adaptation pathways and mitigation for strengthening the resilience of the society to various hazards. Multi- dimensionality of disasters is depicted by various approaches and effective modelling. The book is a synthesis of research papers presented at online International Conference on the theme organized by the Centre for Disaster management, Department of Geography, Jamia Millia Islamia in collaboration with National Institute of Disaster Management and Regional Remote Sensing Centre (North), Indian Space Research Organization (ISRO), New Delhi, India during 02-03 March, 2021. The book has been organized into four parts spreading over 28 chapters. Part I deals with the impact assessment of various disasters. Part II examined ecological and socio-economic vulnerability arising out of the disasters. Part III identifies possible solutions for lessening vulnerability to disasters and effective adaptation strategies. Finally, part IV provides an insight for making the societies resilient to the disasters. The main focus of each chapter was laid implicitly on policy concerns focusing on disaster reduction at spatial scales. The book will immensely be helpful for the researchers, academicians and scientific communities for discussing set of questions necessary for future research. It will attract the attention of functionaries, practitioners, policy makers, training institutes and stakeholders for making appropriate methods of communicating risks and adaptation strategies for disaster management.
    Type of Medium: Online Resource
    Pages: XX, 464 p. 140 illus., 123 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811935671
    Series Statement: Springer Natural Hazards,
    URL: https://doi.org/10.1007/978-981-19-3567-1
    DOI: 10.1007/978-981-19-3567-1
    DDC: 551
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    Financing Investment in Disaster Risk Reduction and Climate Change Adaptation : Asian Perspectives (2022)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Natural disasters. ; Valuation. ; Climatology. ; Natural Hazards. ; Investment Appraisal. ; Climate Sciences.
    Description / Table of Contents: Financing Investment in Disaster Risk Reduction and Climate Change Adaptation: Opportunities and Challenges -- Financing in Climate Change Adaptation -- Recent Trends in Disaster Risk Reduction Investments: A Literature Review -- Exploring people's perception of disaster risk reduction investment for flood management: the case of Jakarta floods in Indonesia -- Factors influencing climate change adaptation investment by local government units in the Philippines -- Financing Infrastructure of DRR: Possibility of integrating investments in maintenance and DRR -- Financing Climate-Resilient Coasts: Tracking Multilateral Aid for Ocean and Coastal Adaptation to Climate Change in Asia-Pacific -- Early Recovery in Humanitarian Response: In the Cases of Four Disasters in the Asia-Pacific Region -- Is the Post Disaster Needs Assessment Important to Investment in Disaster Risk Reduction and Climate Change Adaptation? Lessons from Indonesia and the Philippines Based on Literature Review -- Estimating the Benefits of Flood Protection-Reviewing the Transition of the Cost–Benefit Analysis Manual in Japan and the Implementation Status of the International Flood Protection Project -- Nature-based solutions for river restoration in Japan -- Future Perspectives of Financing Investment in Disaster Risk Reduction and Climate Change Adaptation. .
    Abstract: As the population is growing and urbanization is progressing, higher numbers of people are exposed to disaster risks, especially in the developing countries. Climate change is further worsening the impacts of existing risks and introducing new ones. It is imperative that countries need to invest more in disaster risk reduction (DRR) as well as climate change adaptation (CCA) not only to minimize their impacts but also to build resilience. To date, various international arenas have recommended increasing investment in DRR. The Sendai Framework for DRR, adopted by the UN member states in 2015 during the Third UN World Conference on DRR, emphasizes investment as a priority for decreasing disaster risks and losses. The Yangon Declaration set the goal of doubling investment to address water-related disasters. However, most countries are not able to proactively invest enough in DRR. Understanding the current scale and estimate of investment and its effects is crucial for promoting DRR investment, but such information and estimates are rarely available. This book examines the current investment trends and issues in DRR and CCA. Based on specific case studies, field data and evidence, the book identifies challenges in increasing investment and recommends various investment policies and innovative approaches to sustainable progress towards a resilient future. Chapter 12 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Type of Medium: Online Resource
    Pages: XII, 200 p. 40 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811929243
    Series Statement: Disaster Risk Reduction, Methods, Approaches and Practices,
    URL: https://doi.org/10.1007/978-981-19-2924-3
    DOI: 10.1007/978-981-19-2924-3
    DDC: 551
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    Intelligent Interpretation for Geological Disasters : From Space-Air-Ground Integration Perspective (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Natural disasters. ; Geographic information systems. ; Data mining. ; Geology. ; Natural Hazards. ; Geographical Information System. ; Data Mining and Knowledge Discovery. ; Geology.
    Description / Table of Contents: Chapter 1. Geological disaster: An overview -- Chapter 2. Research methods of geological disasters -- Chapter 3. Principles and methods of intelligent interpretation of geological disasters -- Chapter 4. Intelligent analysis of multi-source long-term landslide ground monitoring data -- Chapter 5. Intelligent monitoring of landslides based on high-resolution optical remote sensing data -- Chapter 6. Deep learning-based remote sensing monitoring of landslide -- Chapter 7. Deep learning-based landslide susceptibility assessment -- Chapter 8. Deep learning-based intelligent recognition of ground fissures -- Chapter 9. Machine learning-based remote sensing monitoring of land subsidence in mining areas -- Chapter 10. Concluding remarks.
    Abstract: This book comprehensively utilizes the new generation of artificial intelligence and remote sensing science and technology to systematically carry out researches on high-precision recognition, monitoring, analysis, and assessment of geological disasters by using different technologies of "ground, airspace, and space-based systems" and different scales of "target-semantic-region". The main contents include: 1) Intelligent interpretation theory and methods of geological disasters, 2) Intelligent analysis of landslide based on long-term ground monitoring data, 3) Deep learning-based remote sensing detection of landslide, 4) Intelligent analysis of landslide evolution based on optical satellite remote sensing data, 5) Intelligent assessment methods of landslide susceptibility, 6) Intelligent recognition of ground figure based on airspace-based remote sensing data, The book is of interest to graduate student, scientific, and technological personnel who work in the area of geological disasters, natural hazards, remote sensing, and artificial intelligence.
    Type of Medium: Online Resource
    Pages: XII, 233 p. 85 illus., 79 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819958221
    URL: https://doi.org/10.1007/978-981-99-5822-1
    DOI: 10.1007/978-981-99-5822-1
    DDC: 551
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    Recent Technologies for Disaster Management and Risk Reduction : Sustainable Community Resilience & Responses (2021)
    Cham :Springer International Publishing :
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    Keywords: Natural disasters. ; Environmental management. ; Environmental monitoring. ; Natural Hazards. ; Environmental Management. ; Environmental Monitoring.
    Description / Table of Contents: Glacial lake outflow hazard and risk probability in Sikkim -- Rockfall Hazard Assessment using RAMMS for the SE Facing Escarpment of Manikaran, Himachal Pradesh, India -- Investigation of Indian Summer Monsoon Rainfall relationship with the Bay of Bengal sea surface temperature and currents -- A comparative study of interpolation methods for mapping soil properties: a case study of eastern part of Madhya Pradesh, India -- Geo Spatial application for coastal morphology changes along the sand mining coast: a case study on Alappad, Kerala.
    Abstract: This book explains to governments, decision makers and disaster professionals the potential uses of recent technologies for disaster monitoring and risk reduction based on the knowledge and experience of prominent experts/researchers in the relevant fields. It discusses the application of recent technological developments for emerging disaster risks in today's societies and deliberates on the various aspects of disaster risk reduction strategies, especially through sustainable community resilience and responses. This book consists of selected invited papers on disaster management, which focus on community resilience and responses towards disaster risk reduction based on experiences, and closely examines the coordinated research activities involving all stakeholders, especially the communities at risk. Many regions of the world and aspects of disaster risk and its management are covered. It is described how recent technologies will support better understanding and action to reduce the number and impact of disasters in future. The principal audience for this book is researchers, urban planners, policy makers, as well as students.
    Type of Medium: Online Resource
    Pages: XV, 479 p. 187 illus., 157 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030761165
    Series Statement: Earth and Environmental Sciences Library,
    URL: https://doi.org/10.1007/978-3-030-76116-5
    DOI: 10.1007/978-3-030-76116-5
    DDC: 551
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    Disaster Resilience and Human Settlements : Emerging Perspectives in the Anthropocene (2023)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Natural disasters. ; Bioclimatology. ; Public health. ; Urban ecology (Biology). ; Architecture. ; Human geography. ; Natural Hazards. ; Climate Change Ecology. ; Public Health. ; Urban Ecology. ; Cities, Countries, Regions. ; Human Geography.
    Description / Table of Contents: Disaster Resilience and Human Settlements: Emerging Perspectives in the Anthropocene -- Leaving nothing to chance: reducing flood risk by evaluating simulation exercises in urban contexts -- Urban growth and increasing flood impact in the city of Palma: a loss of resilience capacity -- Addressing the Impacts of Inland Floods on Informal Housing in Honiara, Solomon Islands -- Adaptive Capacity Analysis of Flood Prone Regions in Bihar, India -- Cruise tourism, risk perception and public narratives in Syracuse, Italy -- Social media in risk perception and disaster management: a geographical perspective -- Environment as a Weapon: History, Gaia, and the Geohazards of War -- Living on Mount Etna between risk, beauty and need: a field survey on villages struck by 2018 earthquake -- Narratives of urban resilience and sustainability in southern Italy: the case studies of Matera (Basilicata) and Filadelfia (Calabria) -- Disaster resilience assessment for drainage network and urban landscape after heavy meteorological events: examples from the middle Adriatic coastal area (Abruzzo Region, Central Italy) -- Revitalizing the wounded territory: the “geo-hiking's” potential -- Sense of belonging and response to climate change: how the relation with local territories influences climate resilience -- From Disasters to the Pandemic: A Study on the EU Solidarity Fund.
    Abstract: This book presents emerging perspectives on disaster resilience and human settlements in the larger context of the Anthropocene. The chapters explore urban and rural perspectives focusing on the current and emerging perspectives on disaster resilience through a holistic approach, involving scientists, humanists, planners, policymakers, and professionals in the global debate.
    Type of Medium: Online Resource
    Pages: XXX, 312 p. 106 illus., 89 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819922482
    Series Statement: Advances in 21st Century Human Settlements,
    URL: https://doi.org/10.1007/978-981-99-2248-2
    DOI: 10.1007/978-981-99-2248-2
    DDC: 551
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    Disaster Risk Reduction for Resilience : Disaster Risk Management Strategies (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Natural disasters. ; Environmental sciences Social aspects. ; Industrial engineering. ; Production engineering. ; Geology. ; Emergency medical services. ; Natural Hazards. ; Environmental Social Sciences. ; Industrial and Production Engineering. ; Geology. ; Emergency Services.
    Description / Table of Contents: Chapter 1. Global Standards for Disaster Risk Reduction -- Chapter 2. Guidelines for Resilient Disaster Risk Reduction: International Law Perspective -- Chapter 3. Strengthening Institutional Resilience: Lessons Learned from COVID-19 Disaster -- Chapter 4. Resilient and Effective Disaster Risk Management Index -- Chapter 5. Mining Hazard Risk Reduction and Resilience -- Chapter 6. Implementing Urban Resilience Strategies with Local Authorities -- Chapter 7. Land Use Planning and Green Infrastructure: Tools for Natural Hazards Reduction -- Chapter 8. Disaster Risk Management: A Resilient Health System -- Chapter 9. Coastal Erosion, Displacement and Resettlement Strategies -- Chapter 10. Resilience and Adaptation Strategies for Urban Heat at Regional, City and Local Scales -- Chapter 11. Combining Disaster Risk Reduction and Climate Change Adaptation for Greater Effectiveness: Lessons from Community-Level Interventions -- Chapter 12. Human Security in Times of Climate Change: Climate Diplomacy for Integrated Action -- Chapter 13. Case-Based Reasoning for Disaster Management: Structure Design for Cascading Disasters Case Base -- Chapter 14. Building Metropolitan Manila’s Institutional Resilience in the Context of Disaster Risk Reduction and Management -- Chapter 15. Exploring Disaster Risk Reduction Strategies In The Sahel: A Multi-Country Study of Burkina Faso, Chad, Mauritania, Niger and Senegal -- Chapter 16. Nexus Between Flooding, Water Quality and Cholera in Nigeria: A Review of Possible Public Health Interventions -- Chapter 17. Sustainable Smart City Planning using Spatial Data and Risk Reduction: A Case Study Siliguri Municipal Corporation -- Chapter 18. Social Representations and Climate Change Teaching in Trainee Social Sciences Teachers -- Chapter 19. Urban Vulnerability to Extreme Heat Events and Climate Change -- Chapter 20. Flooding in Informal Communities Residents’ Response Strategies to Flooding.
    Abstract: This book is part of a six-volume series on Disaster Risk Reduction and Resilience. The series aims to fill in gaps in theory and practice in the Sendai Framework, and provides additional resources, methodologies and communication strategies to enhance the plan for action and targets proposed by the Sendai Framework. The series will appeal to a broad range of researchers, academics, students, policy makers and practitioners in engineering, environmental science and geography, geoscience, emergency management, finance, community adaptation, atmospheric science and information technology. This volume offers the international guidelines and global standards for resilient disaster risk reduction and lessons learned from disasters, particularly the COVID-19 and Cholera pandemics. A resilient health system and an effective disaster risk management Index are then suggested. The book further emphasizes urban resilience strategies with local authorities, adaptation strategies for urban heat at regional, city and local scales, and lessons from community-level interventions. Also addressed are coastal erosion, displacement and resettlement strategies. Land use planning and green infrastructure are suggested as tools for natural hazards reduction. Human security in times of climate change and urban heat at regional, city and local scales is discussed for an integrated action, with case studies based in Manila, Burkina Faso, Chad, Mauritania, Niger, Senegal, Nigeria, India, Spain, and Ghana. Structure design for cascading disasters resulting from mining and flooding is presented and sustainable smart city planning using spatial data is recommended.
    Type of Medium: Online Resource
    Pages: X, 473 p. 121 illus., 97 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030721961
    URL: https://doi.org/10.1007/978-3-030-72196-1
    DOI: 10.1007/978-3-030-72196-1
    DDC: 551
    Language: English
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    Disaster Risk Reduction for Resilience : Disaster and Social Aspects (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Natural disasters. ; Environmental sciences Social aspects. ; Industrial engineering. ; Production engineering. ; Geology. ; Emergency medical services. ; Natural Hazards. ; Environmental Social Sciences. ; Industrial and Production Engineering. ; Geology. ; Emergency Services.
    Description / Table of Contents: Chapter 1. Resilience Assessment at the State Level using the Sendai Framework -- Chapter 2. Disaster Recovery Reform and Resilience -- Chapter 3. Recovery, Development Programs and Place-Based Reconstruction Policy: A Flexible Framework -- Chapter 4. Recovery, Development Programs and Place-Based Reconstruction Policy: The Instrumental Role of Insurance -- Chapter 5. Development of Multi-Hazard Early Warning System in India -- Chapter 6. Cultural and Religious Aspects of Resilience: The Case of Typhoon Ketsana Victims in the Philippines -- Chapter 7. Building Socio-Ecological Resilience by Design for Flood-Prone Waterfront Cities: A Comparative Study of New Orleans of USA, Brisbane of Australia and Christchurch of New Zealand -- Chapter 8. Building Socio-Ecological Resilience against Drought: Case Study from Bhachau, Kachchh, Gujarat -- Chapter 9. Building Socio-Hydrological Resilience for Inclusion-Experience of Co-Operatives in Tanzania -- Chapter 10. Strengthening Climate Resilience and Disaster Risk Reduction: Case Study of the Sahel Adaptive Social Protection -- Chapter 11. Effect of Climate Change on Water Availability and Quality: An Assessment of Socio Resilience in Nigeria -- Chapter 12. A Risk Based Approach to Development Planning -- Chapter 13. Flood Risk Instruction Measures: Adaptation from the School -- Chapter 14. Flood Resilient Cities -- Chapter 15. Coastal Flood Prone Communities and Sustainability -- Chapter 16. Disaster Risk Reduction: Detecting Himalayan Glacial Lake Outburst Floods -- Chapter 17. Communities, Organizations and Partnerships for Climate Change Mitigation and Disaster Reduction -- Chapter 18. Coastal Wetland Hydrologic Resilience To Climatic Disturbances: Concept, Quantification, and Threshold Response -- Chapter 19. Perception of Vulnerable Ultra-Poor Women on Climate Change Impacts and Local Adaptation in a High Flood Prone Area of Bangladesh -- Chapter 20. Climate Change Adaptation and Resilience on Small-Scale Farmers.
    Abstract: This book is part of a six-volume series on Disaster Risk Reduction and Resilience. The series aims to fill in gaps in theory and practice in the Sendai Framework and provides additional resources, methodologies, and communication strategies to enhance the plan for action and targets proposed by the Sendai Framework. The series will appeal to a broad range of researchers, academics, students, policy makers, and practitioners in engineering, environmental science, geography, geoscience, emergency management, finance, community adaptation, atmospheric science and information technology. This volume provides a holistic approach to developing disaster risk reduction strategies and policies, exploring the most effective ways to integrate physical and social science aspects of hazard resilience to better inform local populations. This risk-based approach to community resilience development is used to craft a collaborative system for crisis management, and allows for the implementation of nationally determined contributions (NDCs) through social innovation and community engagement to enhance community emergency response support and preparedness. Readers will also learn about education of disaster risk reduction, human health risk assessment, gendered perspectives in disaster response, recovery, and disaster management legislation.
    Type of Medium: Online Resource
    Pages: XIII, 473 p. 108 illus., 92 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030990633
    URL: https://doi.org/10.1007/978-3-030-99063-3
    DOI: 10.1007/978-3-030-99063-3
    DDC: 551
    Language: English
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  • 98
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    The Phanerozoic Geology and Natural Resources of Egypt (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Geology. ; Petrology. ; Paleontology . ; Earth sciences. ; Geology. ; Petrology. ; Paleontology. ; Earth Sciences.
    Description / Table of Contents: Overall paleogeographic and geodynamic evolution -- Major Groundwater reservoirs in Egypt -- Western Desert Petroleum sources and reservoirs -- Nile Delta Petroleum sources and reservoirs -- Gulf of Suez and Red Sea Petroleum sources and reservoirs -- Off-shore Mediterranean discoveries -- Petroleum Source Rocks of Egypt – An Integrated Palynological and Organic Geochemical Approach: Spatio-temporal studies within the Phanerozoic of Egypt -- Carbonate platform deposits and hydrocarbon potentiality -- Hydrocarbon seepage during the Messinian salinity crisis -- Rare Earth Element in Egypt -- Phanerozoic Stratabound/Stratiform Ore Deposits of Egypt.
    Abstract: The Phanerozoic Geology and Natural Resources of Egypt includes a series of chapters written by highly qualified group of researchers whose expertise is recognized and appreciated not only in Egypt, but also in the world over. The chapters span a wide range of geological subdisciplines including tectonics, paleogeography, stratigraphy, sedimentology, paleontology, groundwater, and energy resources, just to name a few. In this regard, the book provides the reader with ample knowledge about the different facets of the fascinating and always intriguing geology of Egypt since the Precambrian time. For a junior researcher or a geoscience student, the book is a comprehensive, multidisciplinary one-stop resource that they will continue to reference and rely on for years to come. For a more experienced scientist, the book summarizes the current state of knowledge, highlights the magnitude of complexity of the geology of Egypt and northeast Africa, and reveals potential areas where future research should be directed. The book is written in simple, easy to understand English language and contains very useful high-quality illustrations. Last but not least, The Phanerozoic Geology and Natural Resources of Egypt has been reviewed and edited by world class, highly ranked geoscientists from Egypt, Europe, and USA.
    Type of Medium: Online Resource
    Pages: XIX, 742 p. 593 illus., 529 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783030956370
    Series Statement: Advances in Science, Technology & Innovation, IEREK Interdisciplinary Series for Sustainable Development,
    URL: https://doi.org/10.1007/978-3-030-95637-0
    DOI: 10.1007/978-3-030-95637-0
    DDC: 551
    Language: English
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  • 99
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    Disaster Risk Reduction for Resilience : Climate Change and Disaster Risk Adaptation (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Natural disasters. ; Physical geography. ; Environmental sciences Social aspects. ; Water. ; Hydrology. ; Emergency medical services. ; Natural Hazards. ; Earth System Sciences. ; Environmental Social Sciences. ; Water. ; Emergency Services.
    Description / Table of Contents: Chapter 1. Linkage Between Social and Hydrological Systems to Support Resilience: A Case of Freshwater Wetland in Bangladesh -- Chapter 2. Indigenous Approaches to Disaster Risk Reduction, Community Sustainability and Climate Change Resilience -- Chapter 3. The Adaptation to Climate Change in the Primary Education and Approach from the Social Sciences Textbooks -- Chapter 4. Building Climate Change Adaptation and Risk Knowledge In the Arctic Through Preparedness and Contingency Practices -- Chapter 5. Ecological Resilience for Transformative Climate Change Mitigation and Adaptation -- Chapter 6. Mitigating Disaster Risks and Vulnerabilities through Climate Finance and Sustainable Water Management: Policy Considerations for Sub-Saharan Africa and Malawi -- Chapter 7. Assessing Risks and Resilience to Hydro-meteorological Disasters -- Chapter 8. Flood Resilient Plan for Urban Area: A Case Study -- Chapter 9. Flood and Drought Risk Assessment, Climate Change and Resilience -- Chapter 10. Flood Risk Predictions in African Urban Settlements: A Review of Alexandra Township, South Africa -- Chapter 11. Anthropological Study of a Typical Drought Prone Village in India- Strategies for Sustainable Rural Habitat -- Chapter 12. Risk Management of Extreme Precipitation in Mexico: Building Resilience -- Chapter 13. Increasing Temperature Risk and Community Resilience: Urban Aspects -- Chapter 14. Climate Change Adaptation and Sustainable Development -- Chapter 15. Climate Change, Food Security and Resilience: Hydrologic Excess and Deficit Measurement -- Chapter 16. Climate Change and Agro Forestry Resilience Strategy In West Africa’S Cocoa Supply Chain Dynamics -- Chapter 17. Spatial-Temporal Changes of Water Resources: Associated Impact as a Natural Hazard -- Chapter 18. Vulnerability of Climate Change on Water and Sanitation Sectors and Coping Mechanisms by the Communities of Economically Poor Hard to Rich Areas of Bangladesh -- Chapter 19. Climate Governance, Resilience and Enterpreneurship In Nigeria: An Empirical Review.
    Abstract: This book is part of a six-volume series on Disaster Risk Reduction and Resilience. The series aims to fill in gaps in theory and practice in the Sendai Framework, and provides additional resources, methodologies, and communication strategies to enhance the plan for action and targets proposed by the Sendai Framework. The series will appeal to a broad range of researchers, academics, students, policy makers, and practitioners in engineering, environmental science and geography, geoscience, emergency management, finance, community adaptation, atmospheric science, and information technology. This volume offers indigenous approaches to disaster risk reduction, community sustainability and climate change resilience, as well as agro-ecological innovations for improving resilience to climate change. The focus is on adaptation strategies for sustainable terrestrial and marine ecosystems to reduce the impacts of anthropogenic factors that exacerbate disaster risk, including hydro-meteorological services for climate resilience, food security measures in agriculture and livestock, flood mitigation plans, and increased climate change education and awareness. The book concludes with three case studies in Africa detailing the impacts of strengthened climate change resilience measures, adaptive social protections, and improved water availability through hydro-electric technologies. .
    Type of Medium: Online Resource
    Pages: XVI, 457 p. 134 illus., 117 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031221125
    URL: https://doi.org/10.1007/978-3-031-22112-5
    DOI: 10.1007/978-3-031-22112-5
    DDC: 551
    Language: English
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  • 100
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    Theory and Practice of High Resolution Seismic HRS-Geo Technology Application : Optimizing Environment Model Selection (2023)
    Cham :Springer Nature Switzerland :
    Details
    Keywords: Geology. ; Geotechnical engineering. ; Mining engineering. ; Geology. ; Geotechnical Engineering and Applied Earth Sciences. ; Mining and Exploration.
    Description / Table of Contents: Chapter 1: Optimization of The Medium Model in Solving the Inverse Dynamic Problem of Seismics in the HRS-GEO Technology Based on the Spectral Characteristics of Seismic Data -- Chapter 2: Experimental Evaluation of Information Content Regarding the Resolution of the Wave Field and the Choice of Basic Parameters for Solving the Inverse Dynamic Problem of Seismics -- Chapter 3: Features of Integrated Dynamic Interpretation of High Resolution Acoustic Characteristics and Geological Indicators of the Real Environment -- Chapter 4: Wells Data Geophysical Research Interpretation Features -- Chapter 5: Detail Interpretation of High Resolution Seismic Data Timan-Pechora Province.
    Abstract: This book outlines the scientific, methodological and practical foundations for applying High Resolution Seismic HRS-Geo Technology in order to build detailed 2D and 3D seismic acoustic models in the form of acoustic impedances (AI) and reflection coefficients (RC) and the most important geological indicators. The monograph is a continuation of the book by the same authors "Oil and Gas Reservoir Prospecting and Exploration: High-Resolution Seismic HRS techniques and technology". Particular attention is paid to improving the process of searching for AI and RC models using the vector of objective functions, in which various types of residuals between real and model data are iteratively calculated. The well-known criteria for predicting the oil and gas potential of productive deposits from the standpoint of the system analysis principles and the set of geological indicators found from the HRS data are analyzed. The features of solving the main seismogeological problems using HRS-Geo Technology modules are shown, illustrated by numerous examples, and using a special (optimal) processing graph and a set of additional seismic record regularization procedures that provide maximum detail of high-resolution seismic data. The book is meant for scientists and specialists involved in in-depth complex geological interpretation of seismic data in the search and exploration of oil and gas deposits, as well as students of geophysical and geological specialties, graduate students of these specializations and developers.
    Type of Medium: Online Resource
    Pages: XXVIII, 382 p. 170 illus., 169 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031415906
    URL: https://doi.org/10.1007/978-3-031-41590-6
    DOI: 10.1007/978-3-031-41590-6
    DDC: 551
    Language: English
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