Publication Date:
1998-09-25
Description:
REVIEW Although fertilization has been studied for more than a century, the cell surface proteins mediating the process are only now becoming known. Gamete interaction in animals appears to be molecularly complex. Although it is difficult to generalize at present, diversity of structure may be a recurring theme in the evolution of fertilization proteins. Examples of rapid evolution of fertilization proteins by positive selection are known, and concerted evolution can influence the differentiation of gamete recognition proteins between closely related species.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Vacquier, V D -- HD 12986/HD/NICHD NIH HHS/ -- New York, N.Y. -- Science. 1998 Sep 25;281(5385):1995-8.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, CA 92093-0202, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/9748153" target="_blank"〉PubMed〈/a〉
Keywords:
Animals
;
Biological Evolution
;
Egg Proteins/chemistry/genetics/metabolism
;
*Evolution, Molecular
;
Female
;
*Fertilization
;
Male
;
*Membrane Proteins/chemistry/genetics/physiology
;
Mucoproteins/chemistry/genetics/metabolism
;
Receptors, Cell Surface/chemistry/genetics/metabolism
;
Selection, Genetic
;
Sperm-Ovum Interactions
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
