Publication Date:
1981-05-29
Description:
Intracellular recordings were obtained from the goldfish Mauthner cell soma and axon before and after intracellular iontophoresis of drugs that block voltage-sensitive potassium conductance. Analysis of the action potentials generated by the axon hillock-initial segment and by the axon suggest that axonal impulses lack this potassium conductance. Thus, impulse repolarization in the Mauthner axon, and perhaps in other vertebrate central axons, may not involve an active potassium current.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kaars, C -- Faber, D S -- NS 15335/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 1981 May 29;212(4498):1063-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7233201" target="_blank"〉PubMed〈/a〉
Keywords:
4-Aminopyridine
;
Action Potentials/drug effects
;
Aminopyridines/pharmacology
;
Animals
;
Axons/drug effects/*physiology
;
Electric Conductivity
;
Goldfish
;
Myelin Sheath/drug effects/*physiology
;
Potassium/*pharmacology
;
Tetraethylammonium Compounds/pharmacology
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
