Publication Date:
1982-10-29
Description:
Qualitatively distinct patterns of cardiovascular and neuroendocrine responses were observed in male college students during mental work and during sensory intake task performance. During mental work, Type A (coronary-prone) subjects showed greater muscle vasodilatation and more enhanced secretion of norepinephrine, epinephrine, and cortisol than Type B subjects. During sensory intake, Type A hyperresponsivity was found for testosterone and, among those subjects with a positive family history of hypertension, for cortisol. As a demonstration of combined cardiovascular, sympathetic nervous system, and neuroendocrine hyperresponsivity to specific cognitive tasks in Type A subjects, this study breaks ground in the search for mechanisms mediating the increased coronary disease risk among Type A persons.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Williams, R B Jr -- Lane, J D -- Kuhn, C M -- Melosh, W -- White, A D -- Schanberg, S M -- HL-22740/HL/NHLBI NIH HHS/ -- MH-6489/MH/NIMH NIH HHS/ -- MH-70482/MH/NIMH NIH HHS/ -- New York, N.Y. -- Science. 1982 Oct 29;218(4571):483-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7123248" target="_blank"〉PubMed〈/a〉
Keywords:
Behavior/*physiology
;
Blood Pressure
;
Cardiovascular Diseases/etiology
;
Cognition/*physiology
;
Hemodynamics
;
Hormones/blood
;
Humans
;
Hydrocortisone/blood
;
Risk
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
