Publication Date:
1981-01-16
Description:
A movable quartz micropipette, whose tip is sealed with a polymer plug, is used as a liquid-vacuum interface to a mass spectrometer. A light microscope allows observation of, and positioning of, the micropipette tip on the surface of a sample mounted in a perfusion chamber. This forms the basis of an instrument which enables one to study, in vitro, the localization of transepithelial transport of water and other molecules. Some preliminary results from the use of this instrument are presented.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Jarrell, J A -- King, J G -- Mills, J W -- HL-06664/HL/NHLBI NIH HHS/ -- New York, N.Y. -- Science. 1981 Jan 16;211(4479):277-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6969441" target="_blank"〉PubMed〈/a〉
Keywords:
Animals
;
Biological Transport/drug effects
;
Epithelium/metabolism
;
Mass Spectrometry/instrumentation
;
Rana pipiens
;
Skin/*metabolism
;
Urinary Bladder/*metabolism
;
Vasopressins/pharmacology
;
Water/*metabolism
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
