Publication Date:
1984-10-19
Description:
Techniques for on-line coupling of high-performance liquid chromatography with mass spectrometry are reviewed with particular emphasis on those suitable for application to nonvolatile samples. The present status of various techniques is summarized and the strengths and weaknesses of the various approaches are assessed. The potential for future application of recently developed techniques for combined liquid chromatography and mass spectrometry is discussed.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Vestal, M L -- GM24031/GM/NIGMS NIH HHS/ -- GM28291/GM/NIGMS NIH HHS/ -- GM29451/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 1984 Oct 19;226(4672):275-81.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6385251" target="_blank"〉PubMed〈/a〉
Keywords:
Amino Acid Sequence
;
*Chromatography, High Pressure Liquid/instrumentation/methods
;
Computers
;
Ions
;
Lasers
;
*Mass Spectrometry/instrumentation/methods
;
Peptides
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
