Publication Date:
1979-09-14
Description:
When pyramidal tract axons are cut in the adult hamster, fibers degenerate in both anterograde and retrograde directions from the lesion. If the same operation is performed on infant hamsters, however, there is massive regrowth of the severed axons via a new brainstem pathway to their appropriate terminal sites in the medulla and spinal cord. In contrast to previous studies, these results suggest that axons in the mammalian central nervous system damaged early in life may regenerate in a functionally useful way.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kalil, K -- Reh, T -- New York, N.Y. -- Science. 1979 Sep 14;205(4411):1158-61.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/472734" target="_blank"〉PubMed〈/a〉
Keywords:
Age Factors
;
Animals
;
Animals, Newborn/*physiology
;
Axons/physiology
;
Behavior, Animal/physiology
;
Brain Stem/growth & development
;
Cricetinae
;
Functional Laterality
;
*Nerve Regeneration
;
Neural Pathways/growth & development
;
Pyramidal Tracts/*growth & development
;
Spinal Cord/growth & development
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
