Publication Date:
1979-05-25
Description:
The absolute refractory period of neurons projecting from the corticomedial amygdala to the medial preoptic-anterior hypothalamic junction in rats was significantly increased by castration (from 1.01 to 1.61 milliseconds) and decreased again by testosterone (from 1.48 to 0.97 millisecond). Corticomedial amygdala neurons which projected to the capsule of the ventromedial nucleus of the hypothalamus were unaffected. These results demonstrate a specific, direct neuronal effect of testosterone.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kendrick, K M -- Drewett, R F -- New York, N.Y. -- Science. 1979 May 25;204(4395):877-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/220709" target="_blank"〉PubMed〈/a〉
Keywords:
Action Potentials/drug effects
;
Amygdala/drug effects
;
Animals
;
Brain/*drug effects
;
Castration
;
Electric Stimulation
;
Evoked Potentials/drug effects
;
Hypothalamus, Anterior/drug effects
;
Male
;
Preoptic Area/drug effects
;
Rats
;
Synaptic Transmission/drug effects
;
Testosterone/*pharmacology
;
Time Factors
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
