Publication Date:
1999-04-02
Description:
The regulation of members of the knotted1-like homeobox (knox) gene family is required for the normal initiation and development of lateral organs. The maize rough sheath2 (rs2) gene, which encodes a Myb-domain protein, is expressed in lateral organ primordia and their initials. Mutations in the rs2 gene permit ectopic expression of knox genes in leaf and floral primordia, causing a variety of developmental defects. Ectopic KNOX protein accumulation in rs2 mutants occurs in a subset of the normal rs2-expressing cells. This variegated accumulation of KNOX proteins in rs2 mutants suggests that rs2 represses knox expression through epigenetic means.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Timmermans, M C -- Hudson, A -- Becraft, P W -- Nelson, T -- New York, N.Y. -- Science. 1999 Apr 2;284(5411):151-3.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT 06511, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10102816" target="_blank"〉PubMed〈/a〉
Keywords:
Amino Acid Sequence
;
DNA-Binding Proteins/chemistry/genetics/physiology
;
Down-Regulation
;
*Gene Expression Regulation, Plant
;
*Genes, Homeobox
;
Genes, Plant
;
Homeodomain Proteins/*genetics/metabolism
;
Meristem/genetics/growth & development/metabolism
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Molecular Sequence Data
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Mutation
;
Plant Leaves/genetics/growth & development/metabolism
;
Plant Proteins/chemistry/genetics/physiology
;
*Proto-Oncogene Proteins c-myb
;
Repressor Proteins/chemistry/genetics/*physiology
;
Sequence Alignment
;
Zea mays/*genetics/growth & development/metabolism
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
