Publication Date:
2013-11-30
Description:
Production of anilines--key intermediates for the fine chemical, agrochemical, and pharmaceutical industries--relies on precious metal catalysts that selectively hydrogenate aryl nitro groups in the presence of other easily reducible functionalities. Herein, we report convenient and stable iron oxide (Fe2O3)-based catalysts as a more earth-abundant alternative for this transformation. Pyrolysis of iron-phenanthroline complexes on carbon furnishes a unique structure in which the active Fe2O3 particles are surrounded by a nitrogen-doped carbon layer. Highly selective hydrogenation of numerous structurally diverse nitroarenes (more than 80 examples) proceeded in good to excellent yield under industrially viable conditions.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Jagadeesh, Rajenahally V -- Surkus, Annette-Enrica -- Junge, Henrik -- Pohl, Marga-Martina -- Radnik, Jorg -- Rabeah, Jabor -- Huan, Heming -- Schunemann, Volker -- Bruckner, Angelika -- Beller, Matthias -- New York, N.Y. -- Science. 2013 Nov 29;342(6162):1073-6. doi: 10.1126/science.1242005.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Leibniz-Institut fur Katalyse e.V. an der Universitat Rostock, Albert-Einstein Strasse 29a, D-18059 Rostock, Germany.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/24288327" target="_blank"〉PubMed〈/a〉
Keywords:
Aniline Compounds/*chemical synthesis
;
Catalysis
;
Ferric Compounds/*chemistry
;
Hydrogenation
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
