Publication Date:
2007-10-27
Description:
Plant disease resistance (R) proteins recognize matching pathogen avirulence proteins. Alleles of the pepper R gene Bs3 mediate recognition of the Xanthomonas campestris pv. vesicatoria (Xcv) type III effector protein AvrBs3 and its deletion derivative AvrBs3Deltarep16. Pepper Bs3 and its allelic variant Bs3-E encode flavin monooxygenases with a previously unknown structure and are transcriptionally activated by the Xcv effector proteins AvrBs3 and AvrBs3Deltarep16, respectively. We found that recognition specificity resides in the Bs3 and Bs3-E promoters and is determined by binding of AvrBs3 or AvrBs3Deltarep16 to a defined promoter region. Our data suggest a recognition mechanism in which the Avr protein binds and activates the promoter of the cognate R gene.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Romer, Patrick -- Hahn, Simone -- Jordan, Tina -- Strauss, Tina -- Bonas, Ulla -- Lahaye, Thomas -- New York, N.Y. -- Science. 2007 Oct 26;318(5850):645-8.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Institute of Biology, Department of Genetics, Martin-Luther-University Halle-Wittenberg, D-06099 Halle (Saale), Germany.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17962564" target="_blank"〉PubMed〈/a〉
Keywords:
Alleles
;
Bacterial Proteins/genetics/*metabolism
;
Base Sequence
;
Capsicum/*genetics/*microbiology
;
Chromosomes, Artificial, Bacterial
;
Gene Expression Regulation, Plant
;
*Genes, Plant
;
Mixed Function Oxygenases/chemistry/*genetics
;
Molecular Sequence Data
;
Plant Diseases/immunology/microbiology
;
Plant Leaves/genetics/metabolism
;
Plant Proteins/chemistry/genetics
;
*Promoter Regions, Genetic
;
Tobacco/genetics
;
Transcription, Genetic
;
Transformation, Genetic
;
Xanthomonas campestris/genetics/metabolism/*pathogenicity
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
