Publication Date:
2004-06-05
Description:
〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Minna, John D -- Gazdar, Adi F -- Sprang, Stephen R -- Herz, Joachim -- P50CA70907/CA/NCI NIH HHS/ -- New York, N.Y. -- Science. 2004 Jun 4;304(5676):1458-61.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. john.minna@utsouthwestern.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/15178790" target="_blank"〉PubMed〈/a〉
Keywords:
Adenocarcinoma/drug therapy/genetics/metabolism
;
Amino Acid Substitution
;
Antineoplastic Agents/therapeutic use
;
Carcinoma, Non-Small-Cell Lung/drug therapy/*genetics/metabolism
;
Controlled Clinical Trials as Topic
;
Enzyme Inhibitors/therapeutic use
;
Epidermal Growth Factor/metabolism
;
*Genes, erbB-1
;
Humans
;
Japan
;
Ligands
;
Lung Neoplasms/*drug therapy/*genetics/metabolism
;
*Mutation
;
Phosphorylation
;
Protein Structure, Tertiary
;
Quinazolines/*therapeutic use
;
Receptor, Epidermal Growth Factor/*antagonists &
;
inhibitors/chemistry/genetics/metabolism
;
Sequence Deletion
;
Smoking
;
Treatment Outcome
;
United States
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
