Publication Date:
2018-10-17
Description:
Phenome-wide association studies across large population cohorts support drug target validation Phenome-wide association studies across large population cohorts support drug target validation, Published online: 16 October 2018; doi:10.1038/s41467-018-06540-3 Testing the association between genetic variants and a range of phenotypes can assist drug development. Here, in a phenome-wide association study in up to 697,815 individuals, Diogo et al. identify genotype–phenotype associations predicting efficacy, alternative indications or adverse drug effects.
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics