Publication Date:
2018-08-30
Description:
Nrf2 negatively regulates STING indicating a link between antiviral sensing and metabolic reprogramming Nrf2 negatively regulates STING indicating a link between antiviral sensing and metabolic reprogramming, Published online: 29 August 2018; doi:10.1038/s41467-018-05861-7 Understanding how regulators of inflammation affect nucleic acid sensing is important for targeting research against inflammatory diseases and conditions. Here, the authors identify Nrf2 as an important negative regulator of STING and suggest a link between metabolic reprogramming and antiviral cytosolic DNA sensing in human cells.
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics