Publication Date:
2016-09-17
Description:
Sequence element enrichment analysis to determine the genetic basis of bacterial phenotypes Nature Communications, Published online: 16 September 2016; doi:10.1038/ncomms12797 Plasticity and clonal population structure in bacterial genomes can hinder traditional SNP-based genetic association studies. Here, Corander and colleagues present a method to identify variable-length sequence elements enriched in a phenotype of interest, and demonstrate its use in human pathogens.
Electronic ISSN:
2041-1723
Topics:
Biology
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Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics