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Natural products from microbes associated with insects (2016)

Christine Beemelmanns, Huijuan Guo, Maja Rischer and Michael Poulsen

Beilstein-Institut

In: Beilstein Journal of Organic Chemistry

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Publication Date: 2016-02-20

Description: Here we review discoveries of secondary metabolites from microbes associated with insects. We mainly focus on natural products, where the ecological role has been at least partially elucidated, and/or the pharmaceutical properties evaluated, and on compounds with unique structural features. We demonstrate that the exploration of specific microbial–host interactions, in combination with multidisciplinary dereplication processes, has emerged as a successful strategy to identify novel chemical entities and to shed light on the ecology and evolution of defensive associations. Beilstein J. Org. Chem. 2016, 12, 314–327. doi:10.3762/bjoc.12.34

Keywords: biosynthesischemical ecologynatural productssecondary metabolismstructure elucidationsymbiosis

Electronic ISSN: 1860-5397

Topics: Chemistry and Pharmacology

Published by Beilstein-Institut

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