Publication Date:
2015-11-28
Description:
Article Alexander disease is a rare neurological disorder caused by mutations in GFAP, yet it is unclear how glial disruptions lead to neural death. Here, Wang et al . identify a mechanism by which glial-derived nitric oxide leads to neuronal degeneration in fly and mouse models of the disease. Nature Communications doi: 10.1038/ncomms9966 Authors: Liqun Wang, Tracy L. Hagemann, Hermann Kalwa, Thomas Michel, Albee Messing, Mel B. Feany
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics