Publication Date:
2014-07-11
Description:
Article The transcription factor orthodenticle 2 (Otx2) is implicated in head specification in bilaterian lineages, but it is unclear how. Yasuoka et al. now show that this is achieved by the interaction between Otx2 and the transcription factors Lim1 and goosecoid, which activate and repress target genes, respectively. Nature Communications doi: 10.1038/ncomms5322 Authors: Yuuri Yasuoka, Yutaka Suzuki, Shuji Takahashi, Haruka Someya, Norihiro Sudou, Yoshikazu Haramoto, Ken W. Cho, Makoto Asashima, Sumio Sugano, Masanori Taira
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics