Publication Date:
2020
Description:
〈p〉Publication date: 1 April 2020〈/p〉
〈p〉〈b〉Source:〈/b〉 Materials Letters, Volume 264〈/p〉
〈p〉Author(s): Hongyan Tang, Fan Wang, Dan Li, Xuenan Gu, Yubo Fan〈/p〉
〈div xml:lang="en"〉
〈h5〉Abstract〈/h5〉
〈div〉〈p〉This article describes the development of Mg-Sr-RE (RE = La, Nd, Gd) alloys based on a microalloying strategy for stent applications, which aims to control the biosafety and improve the degradation simultaneously. The results reveal that the designed Mg-Sr-RE alloys are close to a single-phase solid solution with the total alloying addition restricted to 0.5 wt%. Mg-Sr-RE alloy exhibits 0.5–2 times increment of ductility while 45–66% slower corrosion rates than binary Mg-Sr. Both the indirect and direct cell assays indicate that Mg-Sr-RE alloys reduce HAVSMCs proliferation, stimulate the HUVECs growth and endothelialization related gene expression, which may benefit in the healing of stent-assisted vascular injuries.〈/p〉〈/div〉
〈/div〉
Print ISSN:
0167-577X
Electronic ISSN:
1873-4979
Topics:
Chemistry and Pharmacology
,
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
