ISSN:
1661-9897
Source:
Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
Topics:
Physics
Notes:
Regular arrays of micro-pillars and nano-grooves structures on the silicon wafer arefabricated by using soft lithography, and the three dimension morphology of textured surface isobserved by using scanning electron microscopy (SEM) and atomic force microscope (AFM). Thestatic water contact angles are measured by using contact angle meter to characterize thewettabilities of these surfaces. To investigate how the presence of topography and the variations ofwettability affect the haemocompatibility of textured surface contacted with blood, differentpatterned surfaces are designed and fabricated, and blood platelet adhesion test is carried out onthese surfaces. The adhesion and coagulation of platelets are inspected by scanning electronmicroscopy (SEM). Experimental data presented in this paper indicate that different surfaceroughness and wettability are the important factors for blood platelet adhesion. The amount ofadsorbed blood platelet is low on textured surfaces, compared with that on the flat surface.Especially, there is no coagulation and activation on the surface with nanometer grooves. That is tosay, the superhydrophobic surface is apt to decrease blood platelet adhesion. The study suggests thatsurface with suitable wettabililty and textured structures exhibits superior blood compatibility
Type of Medium:
Electronic Resource
URL:
http://www.tib-hannover.de/fulltexts/2011/0528/01/43/transtech_doi~10.4028%252Fwww.scientific.net%252FJNanoR.2.129.pdf
