ISSN:
1013-9826
Source:
Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
Topics:
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
Notes:
The design and processing of 3D macroporous bioactive scaffolds is one of themilestones for the progress of bone tissue engineering and bone regeneration. Calcium phosphatebased ceramics are among the most suitable materials, due to their similarity to the bone mineral.Specifically, beta-tricalcium phosphate (β-TCP) is known to be a resorbable and bioactive material, withwell established applications as bone regeneration material. The aim of this work is to explore a newroute to obtain β-TCP macroporous scaffolds starting from calcium phosphate cements. To this endfoamed calcium phosphate cement, composed of alpha tricalcium phosphate as starting powder wasused as initial material. The set foamed structures, made of calcium deficient hydroxyapatite(CDHA) were sintered to obtain the final β-TCP macroporous architecture. The interconnectedmacroporosity was maintained, whereas the porosity in the nanometric range was strongly reducedby the sintering process. The sintering produced also an increase in the mechanical properties of thescaffold
Type of Medium:
Electronic Resource
URL:
http://www.tib-hannover.de/fulltexts/2011/0528/01/56/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.361-363.323.pdf
