ISSN:
1476-4687
Source:
Nature Archives 1869 - 2009
Topics:
Biology
,
Chemistry and Pharmacology
,
Medicine
,
Natural Sciences in General
,
Physics
Notes:
[Auszug] As human chromosomes are lost in mouse x human hybridomas3'4 it is difficult to obtain interspecies hybridomas that secrete human antibodies, because such hybrids must retain both of the two human chromosomes that carry the rearranged genes for the human light and heavy immunoglobulin chains3'4. ...
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1038/288488a0