ISSN:
1072-8368
Source:
Nature Archives 1869 - 2009
Topics:
Biology
,
Medicine
Notes:
[Auszug] Here we report the use of an objective computer algorithm in the design of a hyperstable variant of the Streptococcal protein G β1 domain (Gβ1). The designed seven-fold mutant, Gβ1-c3b4, has a melting temperature in excess of 100 °C and an enhancement in thermodynamic stability ...
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1038/nsb0698-470