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Novel instrument for measurement of multidimensional fluorescence detected circular dichroism (1986)

Thomas, Mark ; Patonay, Gabor ; Warner, Isiah

[S.l.] : American Institute of Physics (AIP)

Review of Scientific Instruments 57 (1986), S. 1308-1313

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ISSN: 1089-7623

Source: AIP Digital Archive

Topics: Physics , Electrical Engineering, Measurement and Control Technology

Notes: A new microprocessor-controlled multichannel spectrometer for the measurement of fluorescence detected circular dichroism (FDCD) is presented. Spectra of model steroid compounds are provided to demonstrate the analytical utility of multichannel FDCD over the classical circular dichroism measurement. A detection limit of 3.05×10−8 M was determined for a solution of estrone based on a signal/noise ratio of 2 as a lower limit. The optics and electronics for the rapid acquisition of multichannel FDCD data are described in detail.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1063/1.1138594

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