ISSN:
1432-2048
Keywords:
Carnitine palmitoyltransferase (location, function)
;
Cotyledon (β-oxidation)
;
Microbody
;
Mitochondrion
;
β-Oxidation
;
Pisum (β-oxidation)
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Abstract Two sites for β-oxidation of fatty acids in pea (Pisum sativum L.) cotyledons exist. One site is the microbody, the other the mitochondrion. Mitochondrial β-oxidation of fatty acids is carnitine-dependent. The fatty acid permeates the membrane as palmitoylcarnitine which is formed from cytosolic-side palmitoyl-CoA by a carnitine palmitoyltransferase located on the exterior face of the inner mitochondrial membrane as a peripheral protein. A single-gated pore integral membrane translocator is proposed to exchange the palmitoylcarnitine for carnitine or acetylcarnitine across the membrane. An internal (matrix side) carnitine palmitoyltransferase then reforms palmitoyl-CoA which enters β-oxidation and subsequently the tricarboxylic-acid cycle.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00402972
