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Relationship between ADH activity and behavioral response to environmental alcohol inDrosophila (1980)

Gelfand, Lewis J. ; McDonald, John F.

Springer

Behavior genetics 10 (1980), S. 237-249

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ISSN: 1573-3297

Keywords: Drosophila ; behavior ; ADH activity ; adaptation ; evolution ; alcohol avoidance ; Adh genotypes

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Psychology

Notes: Abstract Three alcohol dehydrogenase genotypes, homozygous for either the electrophoretically fast, slow, or null allele at theAdh locus inD. melanogaster, were tested for relative larval alcohol preference behavior (APB) over a range of ethanol concentrations. Differences in behavior between genotypes were not significant at concentrations below 10%. At concentrations greater than 10%, avoidance behavior was negatively correlated with the relative ADH activity levels of the genotypes tested. A model based on the differential buildup of toxic acetaldehyde is proposed to explain the avoidance response.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF01067770

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