ISSN:
1573-1111
Keywords:
Bipyridine
;
bipyridine ligand
;
complexation
;
complex chemistry
;
complex formation
;
cyclovoltammetry
;
electrochemical mediator
;
electrochemical reduction
;
electrochemistry
;
NAD+
;
NADH
;
Rh3+
;
Rh+
;
Rh complex
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract The tris-bipyridine ligand3a and its stoichiometric Rh3+ complex have been prepared. Cyclovoltammograms of the complex at pH 7.4 using a glassy carbon disk electrode reveal a strong reduction peak at −620 mV and two weak reduction peaks at more negative voltage. The reduction potential of the new complex is shifted by 300 mV to more positive values as compared to [Rh(bipy)3]3+. There is no reversible reoxidation peak of the Rh(I) complex formed due to the decomplexation of one of the three bipyridine units in the course of the transition Rh(III)→Rh(I). The Rh(III) complex of3a was also studied with respect to its function as a possible redox mediator for the electrochemical regeneration of NADH from NAD+. The preparative electrolysis of the Rh3+ complex of3a in the presence of NAD+ yields a selective formation of NADH, whereas NAD dimers were not detected. On the other hand, a significant acceleration of this reaction compared to [Rh(bipy)3]3+ was not observed.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00656589
