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Effect of cationic groups on the adhesivity of peritoneal macrophages to polymeric beads (1995)

Smetana, K. ; Jelínková, M. ; Vacík, J. ; [et al.]

Springer

Journal of materials science 6 (1995), S. 32-34

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ISSN: 1573-4838

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine , Technology

Notes: Abstract This study demonstrates the adhesion of macrophages to polymer beads from a copolymer of hydroxyethyl methacrylate and dimethyl aminoethyl methacrylate intraperitoneally injected into the rat. Dimethyl aminoethyl methacrylate exhibited a stimulatory effect on macrophage adhesion 5 h after injection of the beads. Electron microscopy demonstrated protein adsorption on the surface of the beads. Protein fibres between the cell surface and beads were observed. The experimental system used minimizes the influence of tissue damage at macrophage recognition of polymers. This method seems to be suitable for short-term investigation of macrophage-polymer interaction.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00121244

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