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Immunocytochemical demonstration of calmodulin in cells secreting by exocytosis (1985)

Egsmose, C. ; Bock, E. ; Møllgård, K. ; [et al.]

Springer

Cellular and molecular life sciences 41 (1985), S. 1340-1342

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ISSN: 1420-9071

Keywords: Immunocytochemistry ; calmodulin ; secretory granules

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Medicine

Notes: Summary Calmodulin is a regulator of several calcium-dependent cellular processes. It has been suggested that it plays a role in the mechanism of secretion. Employing an indirect immunoperoxidase technique at the light microscope level, this study demonstrates the presence of calmodulin in several exocytotic cells (mast cells, thyroid follicular cells, neurohypophyseal neurosecretory terminals, pancreaticβ-cells and pancreatic acinus cells) in rat and man. The positive staining reaction for calmodulin was granular and at least in the case of rat mast cells it appeared to be associated with the granule membrane.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF01952085

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