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Teratologische Prüfung einiger Thalidomid-Metabolite (1971)

Köhler, F. ; Meise, W. ; Ockenfels, H.

Springer

Cellular and molecular life sciences 27 (1971), S. 1149-1150

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ISSN: 1420-9071

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Medicine

Notes: Summary The teratogenicity of 3 hydrolysis products of thalidomide, 2-(o-carboxybenzamido)-glutaric acid, phthalic acid and glutamic acid, was determined by administering 25% Tween 20 i.p. to pregnant SWS-mice. Under these experimental conditions, the tested products were devoid of any teratogenic properties, whereas thel-isomer of phthaloyl-glutamic acid showed the well-known embryotoxic and teratogenic activity.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF02286890

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