ISSN:
1022-1344
Keywords:
Chemistry
;
Polymer and Materials Science
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
,
Physics
Notes:
We consider numerically, in the framework of the lakes-straits model, the mobility of a DNA chain under field-inversion gel-electrophoresis (FIGE). Here we investigate the role of the gel's structure on the mobility. We consider two situations: (i) a DNA chain fragment is bounded by two straits (narrow gateways) at a fixed distance, but is otherwise free, and (ii) the fragment is, in addition, confined with in a closed volume (pore). We calculate the tension on the DNA fragment in the two cases. For Gaussian chains we evaluate the corresponding statistical weights exactly, using a cellular automation algorithm. We find that the resulting tension differs drastically in the two models considered. Nonetheless this difference influences only weakly the overall FIGE mobility.
Additional Material:
4 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/mats.1995.040040110
