ISSN:
0170-2041
Keywords:
Alkaloids
;
Deplancheine
;
Indoles
;
β-Carbolines
;
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
A Short and Effective Synthesis of rac-DeplancheineTryptamine and dimethyl methoxyallylidenemalonate (1) react to give the divinylogous urethane 2, which yields by reaction with acroleine under acid catalysis the β-carboline 3a. Reductive decarboxylation gives the target compound deplancheine (4a) in excellent overall yield.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jlac.1992199201217