ISSN:
0170-2041
Keywords:
Pyridazine, derivatives
;
Pyrazolo-pyridazine, derivative
;
Pyrido-pyridazine, derivative
;
Isoxazolo-pyridazine, derivative
;
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The pyridazines 3, 4, 5, and 7 were obtained by reaction of the hydrazone derivatives 2 with several reagents. By treatment of 5 with acetic acid/hydrochloric acid, the pyrazolo[4,3-c]-pyridazine 6 was formed. The pyrido-pyridazine derivatives 8 and 9 were obtained by reaction of 2 and 3 with malononitrile and ethyl cyanoacetate, respectively, and the isoxazolo-pyridazines 11 by reaction of 3a, b with hydroxylamine hydrochloride in ethanolic sodium ethoxide solution. The intermediate 9 was separated by reaction of 3a, b with hydroxylamine hydrochloride in ethanolic sodium acetate solution.
Additional Material:
2 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jlac.199019900153
