ISSN:
1434-193X
Schlagwort(e):
Natural products
;
Antibiotics
;
Macrolides
;
Asymmetric synthesis
;
Chiral sulfoxide
;
Chemistry
;
General Chemistry
Quelle:
Wiley InterScience Backfile Collection 1832-2000
Thema:
Chemie und Pharmazie
Notizen:
This paper describes an efficient stereocontrolled and convergent approach towards the C1-C13 polyol fragment of amphotericin B. The strategy is based on the stereoselective reduction of a chiral β,γ-dioxo-ε-sulfinyl ester to obtain anti- or syn-1,3-diols.
Zusätzliches Material:
1 Ill.
Materialart:
Digitale Medien