ISSN:
0009-2940
Keywords:
Carbene complexes
;
Chromium
;
Cycloadditions
;
Cyclopropanecarboxylic and derivatives
;
Chemistry
;
Inorganic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The intermolecular Pauson-Khand reactions of ethyl trans-2-phenylethynylcyclopropanecarboxylate (1t) and [amino-(trans-2-phenylethynylcyclopropyt)methylidene]pentacarbonylchromium (9) with norbornane lead to ester and metal carbene functionalized exo-tricyclodecenones 3b-6 and 13-16, respectively, in moderate to high yields. The incorporation of the alkyne is moderately regioselective but less diastereoselective. Pairs of diastereomers are isolated after column chromatography, which can subsequently be separated by recrystallization. The minor diastereomer 3 and the major diastereomer 15 are characterized by X-ray structure analysis.
Additional Material:
2 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/cber.19971300410