ISSN:
0009-2940
Schlagwort(e):
Dipeptides
;
Cysteine
;
Histidine
;
Zinc complexes
;
Chemistry
;
Inorganic Chemistry
Quelle:
Wiley InterScience Backfile Collection 1832-2000
Thema:
Chemie und Pharmazie
Notizen:
The dipeptides Ac-Cys-Val-OH (1a) and Ac-His-Val-OH (1b), H-Gly-Cys-OEt (2a) and H-Val-His-OEt (2b) as well as Z-Asp-Cys-OH (3a) and Z-Asp-His-OH (3b) (Z = benzyloxycarbonyl) were prepared, and their zinc complexation was investigated by potentiometric methods. They have in common that in addition to the cysteine thiolate or the histidine imidazole the second amino acid offers one donor function. The complex stabilities are very close to those of the corresponding difunctional derivatives of the single amino acids cysteine or histidine. This indicates the presence of seven- to ten-membered chelate rings.
Zusätzliches Material:
3 Ill.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1002/cber.19961291016
