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Enzyme immobilization on heparin (1978)

Torchilin, V. P. ; Il'Ina, E. V. ; Streltsova, Z. A. ; [et al.]

Hoboken, NJ : Wiley-Blackwell

Journal of Biomedical Materials Research 12 (1978), S. 585-590

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ISSN: 0021-9304

Keywords: Chemistry ; Polymer and Materials Science

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Medicine , Technology

Notes: We describe the preparation and some of the properties of heparin-bound α-chymotrypsin that were obtained via activation of heparin with water-soluble carbodiimide. Immobilized enzyme has unchanged kinetic characteristics toward low-molecular-weight and macromolecular substrates. The heparin-bound enzymes could have a wide range of medical applications.

Additional Material: 2 Ill.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1002/jbm.820120502

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