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Diffusivity of oxygen into carriers entrapping whole cells (1989)

Sun, Yan ; Furusaki, Shintaro ; Yamauchi, Aizo ; [et al.]

New York, NY [u.a.] : Wiley-Blackwell

Biotechnology and Bioengineering 34 (1989), S. 55-58

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ISSN: 0006-3592

Keywords: Chemistry ; Biochemistry and Biotechnology

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology

Notes: The effective diffusivity of oxygen, De, in Ca-alginate and PVA-SbQ gels was measured using a two-chamber vessel with a membrane between the two chambers. The effect of cell density, Cc, on De in Ca-alginate gels was studied. The effective diffusivity of oxygen decreased with increasing cell density, to Cc = 170 kg dry cells/m3 gel. The dependency of De on cell density was discussed in terms of a random-pore model. The model correlated well with experimental data, i.e., kDe/D0 = 0.86(1 - 1.47 × 10-3 Cc)2. Here, k is the partition coefficient, and D0 is diffusivity in water.

Additional Material: 3 Ill.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1002/bit.260340107

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