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  • 1
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 21 (1979), S. 357-391 
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The existence of rapid and slow transients in the continuous culture of microorganisms when limited by one of the nutrients is revealed on the basis of a new method of mathematical analysis that separates these rapid and slow transients. The slow transient occurs along one and the same line of slow movement (LSM) independent of the initial state of the culture. This line is situated in the “substrate concentration S - biomass concentration X” coordinate system and rigidly connects these concentrations. When the initial values of S and X do not lie on this line, the rapid process occurring before the slow one leads the culture to LSM. Arrival to LSM occurs owing to alteration of S at almost constant X. The biomass concentration is always a slow variable but tne substrate concentration is both a rapid and a slow variable. A number of regularities of this time hierarchy are analyzed. A comprehensive description of the dynamics of continuous cultivation of microorganisms including different ways of supplying limiting nutrients is presented. Phaseplane plots of microbial cultures and the families of isochrones (lines making it possible to determine exactlythe transient duration) are given. The isochrone theory is described in the appendix.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
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