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Optimal control of an enzyme reaction subject to enzyme deactivation. I. Batch process (1970)

Ho, Lewis Y. ; Humphrey, Arthur E.

New York, NY [u.a.] : Wiley-Blackwell

Biotechnology and Bioengineering 12 (1970), S. 291-311

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ISSN: 0006-3592

Keywords: Chemistry ; Biochemistry and Biotechnology

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology

Notes: This paper is concerned with the study of an enzymatic system in a repeated batch process where the enzyme is subject to deactivation. The particular system studied was the enzymatic hydrolysis of Penicillin G to 6-aminopenicillanic acid. Utilizing standard optimization techniques, pH and temperature control policies were determined that would maximize the product yield.

Additional Material: 13 Ill.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1002/bit.260120209

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