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Extracellular calcium modulates proliferation of factor dependent hemopoietic cells (1993)

Martínez, Jorge ; Santibañez, Juan F.

New York, NY [u.a.] : Wiley-Blackwell

Cell Biochemistry and Function 11 (1993), S. 101-105

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ISSN: 0263-6484

Keywords: Calcium ; cell proliferation ; calcium blockers ; FDCP-1 cells ; Chemistry ; Biochemistry and Biotechnology

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Biology , Medicine

Notes: Blockade of the calcium channel inhibited, in a dose-dependent manner, the proliferation of the IL-3 dependent FDCP-1 cell line and normal murine bone marrow cells. Similar results were obtained by lowering the amount of extracellular calcium using specific chelators or a calcium-free medium. These results suggest that factor-dependent cell proliferation is highly sensitive to fluctuations in the concentration of extracellular calcium.

Additional Material: 4 Ill.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1002/cbf.290110205

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