ISSN:
0173-0835
Keywords:
Chemistry
;
Biochemistry and Biotechnology
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Biology
,
Chemistry and Pharmacology
Notes:
Murine Cu, Zn-superoxide dismutase (SOD) from erythrocytes has three isozymes, SOD-1A (pI 6.4), B (pI 5.7) and C (pI 5.0). It has been suggested that SOD-1A is formed epigenetically by asymmetric modification of SOD-1B where as SOD-1C is produced by treatment of superoxide dismutase with hydrogen peroxide. On two-dimensional gel electrophoretic analysis, each isozyme shows two forms, easily permuted into each other, and hence supposed to be in equilibrium. The zymogram patterns of murine liver, kidney, heart and brain are the same as those in erythrocytes although SOD activity levels are different in these tissues.
Additional Material:
5 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/elps.1150070907
