ISSN:
0030-493X
Keywords:
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Hydrogen/deuterium exchange and rearrangements in the molecular ion of o-(methyl-d3-thio)benzoic acid lead to fragment ions [M—OD]+ as well as [M—OH]+ and m/z 106 and 107, just as in the molecular ion of o-methoxybenzoic acid. However, the fragment ion m/z 108 has the composition C6H4S rather than C6H2D3CO as it does in the case of o-methoxy-d3-benzoic acid. By varing the repeller potential at 10 eV (and thus the residence time in the ion source), the corresponding fragments are seen to be formed more slowly from the methylthio acid than from the methoxy acid, which leads to the conclusion that H/D exchange between carboxyl and labelled methylthio is slower than it is between carboxyl and labelled methoxyl.
Additional Material:
2 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/oms.1210200903