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Liquid chromatography mass spectrometry of dexamethasone and betamethasone (1983)

Cairns, Thomas ; Siegmund, Emil G. ; Stamp, John J. ; [et al.]

Chichester : Wiley-Blackwell

Biological Mass Spectrometry 10 (1983), S. 203-208

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ISSN: 0306-042X

Keywords: Chemistry ; Analytical Chemistry and Spectroscopy

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Chemistry and Pharmacology

Notes: Chemical ionization mass spectra of dexamethasone and betamethasone have been obtained via liquid chromatography mass spectrometry using a moving belt interface. These results have confirmed a concentration-dependent competition between thermal degradation and vaporization. Caution should be exercized when dealing with molecules subject to thermal instability since sample introduction via the mechanical transport system does not guarantee evaporation without thermal decomposition.

Additional Material: 2 Ill.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1002/bms.1200100317

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