ISSN:
0306-042X
Keywords:
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The mass spectral fragmentations of 3-deazauracil, 3-deazauridine and selected derivatives are described. Fragmnetations give rise to ions diagnostic of specific positions in the base and/or sugar moieties. Ion structure are rationalized based on isotopic labeling, metastable ion analysis and high resolution data. The spectrum of 3-deazauracil resembles that of cytosine more closely than uracil. The spectrum of 3-deazauridine is almost identical to that of 1-β-D-arabinofuranosyl cytosine, closely resembles that of cytidine and differs significantly from uridine. The formation of a strong b+41 ion in the spectrum of 3-deazauridine raises questions on the utility of the b+41 ions in assigning a cytidine structure to an unknown nucleoside based solely on this ion.
Additional Material:
6 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/bms.1200100108
