ISSN:
0935-6304
Keywords:
Gas chromatography, GC
;
Glass capillary columns
;
Urine assay
;
Ibuprofen and metabolites
;
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
A selective and sensitive high resolution gas chromatography assay for simultaneous determination of Ibuprofen and its major metabolites in urine is described. Biological samples were collected from healthy volunteers after a single topical administration of the drug in gel form. The chromatographic system, developed on a WCOT OV-1 glass capillary column, ensured a clear separation of Ibuprofen and its metabolites and their quantitative evaluation.
Additional Material:
3 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jhrc.1240080822