ISSN:
0947-3440
Schlagwort(e):
Thiaoleic acids
;
Chlorella
;
Oleyl desaturase
;
Chemistry
;
Organic Chemistry
Quelle:
Wiley InterScience Backfile Collection 1832-2000
Thema:
Chemie und Pharmazie
Notizen:
New thiaoleic acid methyl esters 1 have been prepared as models for studies on Δ12-saturation, Convergent synthetic pathways to those acids from the 10-(tetrahydropyranyloxy)-dec-1-yne 2 are described. After saponification, their inhibitory effect on the in vivo desaturation of [1-14C] oleic acid into [1-14C] linoleic acid has been evaluated using green algae, Chlorella sorokiniana, as a biological model. This result may indicate that the oleyl-desaturase initiates dehydrogenation of a normal substrate by hydrogen atom abstraction at C-13.
Zusätzliches Material:
1 Tab.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1002/jlac.199719970108
